Works by Thrasher, Adrian J.

Results: 132
    1

    Intrinsic dendritic cell abnormalities in Wiskott-Aldrich syndrome.

    Published in:
    European Journal of Immunology, 1998, v. 28, n. 10, p. 3259, doi. 10.1002/(SICI)1521-4141(199810)28:10<3259::AID-IMMU3259>3.0.CO;2-B
    By:
    • Binks, Michael;
    • Jones, Gareth E.;
    • Brickell, Paul M.;
    • Kinnon, Christine;
    • Katz, David R.;
    • Thrasher, Adrian J.
    Publication type:
    Article
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    WASP-mediated regulation of anti-inflammatory macrophages is IL-10 dependent and is critical for intestinal homeostasis.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03670-6
    By:
    • Biswas, Amlan;
    • Shouval, Dror S.;
    • Griffith, Alexandra;
    • Goettel, Jeremy A.;
    • Field, Michael;
    • Yu Hui Kang;
    • Konnikova, Liza;
    • Janssen, Erin;
    • Redhu, Naresh Singh;
    • Thrasher, Adrian J.;
    • Chatila, Talal;
    • Kuchroo, Vijay K.;
    • Geha, Raif S.;
    • Notarangelo, Luigi D.;
    • Sung-Yun Pai;
    • Horwitz, Bruce H.;
    • Snapper, Scott B.
    Publication type:
    Article
    6

    Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells.

    Published in:
    Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01676-0
    By:
    • Lee, Pamela P.;
    • Lobato-Márquez, Damián;
    • Pramanik, Nayani;
    • Sirianni, Andrea;
    • Daza-Cajigal, Vanessa;
    • Rivers, Elizabeth;
    • Cavazza, Alessia;
    • Bouma, Gerben;
    • Moulding, Dale;
    • Hultenby, Kjell;
    • Westerberg, Lisa S.;
    • Hollinshead, Michael;
    • Lau, Yu-Lung;
    • Burns, Siobhan O.;
    • Mostowy, Serge;
    • Bajaj-Elliott, Mona;
    • Thrasher, Adrian J.
    Publication type:
    Article
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    Gene therapy for primary immunodeficiency.

    Published in:
    Human Molecular Genetics, 2019, v. 28, p. R15, doi. 10.1093/hmg/ddz170
    By:
    • Booth, Claire;
    • Romano, Rosa;
    • Roncarolo, Maria Grazia;
    • Thrasher, Adrian J
    Publication type:
    Article
    15

    Hematopoietic Stem Cell Gene Therapy for Adenosine Deaminase-Deficient Severe Combined Immunodeficiency Leads to Long-Term Immunological Recovery and Metabolic Correction.

    Published in:
    Science Translational Medicine, 2011, v. 3, n. 97, p. 1, doi. 10.1126/scitranslmed.3002716
    By:
    • Gaspar, H. Bobby;
    • Cooray, Samantha;
    • Gilmour, Kimberly C.;
    • Parsley, Kathryn L.;
    • Fang Zhang;
    • Adams, Stuart;
    • Bjorkegren, Emma;
    • Bayford, Jinhua;
    • Brown, Lucinda;
    • Davies, E. Graham;
    • Veys, Paul;
    • Fairbanks, Lynette;
    • Bordon, Victoria;
    • Petropolou, Theoni;
    • Kinnon, Christine;
    • Thrasher, Adrian J.
    Publication type:
    Article
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    Effective gene therapy with nonintegrating lentiviral vectors.

    Published in:
    Nature Medicine, 2006, v. 12, n. 3, p. 348, doi. 10.1038/nm1365
    By:
    • Yáñez-Muñoz, Rafael J.;
    • Balaggan, Kamaljit S.;
    • MacNeil, Angus;
    • Howe, Steven J.;
    • Schmidt, Manfred;
    • Smith, Alexander J.;
    • Buch, Prateek;
    • MacLaren, Robert E.;
    • Anderson, Patrick N.;
    • Barker, Susie E.;
    • Duran, Yanai;
    • Bartholomae, Cynthia;
    • von Kalle, Christof;
    • Heckenlively, John R.;
    • Kinnon, Christine;
    • Ali, Robin R.;
    • Thrasher, Adrian J.
    Publication type:
    Article
    21

    Publisher Correction: In Utero Gene Therapy (IUGT) Using GLOBE Lentiviral Vector Phenotypically Corrects the Heterozygous Humanised Mouse Model and Its Progress Can Be Monitored Using MRI Techniques.

    Published in:
    2019
    By:
    • Shangaris, Panicos;
    • Loukogeorgakis, Stavros P.;
    • Subramaniam, Sindhu;
    • Flouri, Christina;
    • Jackson, Laurence H.;
    • Wang, Wei;
    • Blundell, Michael P.;
    • Liu, Shanrun;
    • Eaton, Simon;
    • Bakhamis, Nahla;
    • Ramachandra, Durrgah Latchumi;
    • Maghsoudlou, Panayiotis;
    • Urbani, Luca;
    • Waddington, Simon N.;
    • Eddaoudi, Ayad;
    • Archer, Joy;
    • Antoniou, Michael N.;
    • Stuckey, Daniel J.;
    • Schmidt, Manfred;
    • Thrasher, Adrian J.
    Publication type:
    Correction Notice
    22

    In Utero Gene Therapy (IUGT) Using GLOBE Lentiviral Vector Phenotypically Corrects the Heterozygous Humanised Mouse Model and Its Progress Can Be Monitored Using MRI Techniques.

    Published in:
    Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-48078-4
    By:
    • Shangaris, Panicos;
    • Loukogeorgakis, Stavros P.;
    • Subramaniam, Sindhu;
    • Flouri, Christina;
    • Jackson, Laurence H.;
    • Wang, Wei;
    • Blundell, Michael P.;
    • Liu, Shanrun;
    • Eaton, Simon;
    • Bakhamis, Nahla;
    • Ramachandra, Durrgah Latchumi;
    • Maghsoudlou, Panayiotis;
    • Urbani, Luca;
    • Waddington, Simon N.;
    • Eddaoudi, Ayad;
    • Archer, Joy;
    • Antoniou, Michael N.;
    • Stuckey, Daniel J.;
    • Schmidt, Manfred;
    • Thrasher, Adrian J.
    Publication type:
    Article
    23

    Restoring the natural tropism of AAV2 vectors for human liver.

    Published in:
    Science Translational Medicine, 2020, v. 12, n. 560, p. 1, doi. 10.1126/scitranslmed.aba3312
    By:
    • Cabanes-Creus, Marti;
    • Hallwirth, Claus V.;
    • Westhaus, Adrian;
    • Ng, Boaz H.;
    • Liao, Sophia H.Y.;
    • Zhu, Erhua;
    • Navarro, Renina Gale;
    • Baltazar, Grober;
    • Drouyer, Matthieu;
    • Scott, Suzanne;
    • Logan, Grant J.;
    • Santilli, Giorgia;
    • Bennett, Antonette;
    • Ginn, Samantha L.;
    • McCaughan, Geoff;
    • Thrasher, Adrian J.;
    • Agbandje-McKenna, Mavis;
    • Alexander, Ian E.;
    • Lisowski, Leszek
    Publication type:
    Article
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    Patching up hematopoietic stem cells.

    Published in:
    Nature Biotechnology, 2015, v. 33, n. 12, p. 1236, doi. 10.1038/nbt.3425
    By:
    • Santilli, Giorgia;
    • Thrasher, Adrian J
    Publication type:
    Article
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    Gene therapy matures in the clinic.

    Published in:
    Nature Biotechnology, 2012, v. 30, n. 7, p. 588, doi. 10.1038/nbt.2290
    By:
    • Seymour, Leonard W;
    • Thrasher, Adrian J
    Publication type:
    Article
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    Gene therapy: great expectations?

    Published in:
    Medical Journal of Australia, 2005, v. 182, n. 9, p. 440, doi. 10.5694/j.1326-5377.2005.tb06780.x
    By:
    • Thrasher, Adrian J
    Publication type:
    Article
    41

    Biallelic JAK1 mutations in immunodeficient patient with mycobacterial infection.

    Published in:
    Nature Communications, 2016, v. 7, n. 12, p. 13992, doi. 10.1038/ncomms13992
    By:
    • Eletto, Davide;
    • Burns, Siobhan O.;
    • Angulo, Ivan;
    • Plagnol, Vincent;
    • Gilmour, Kimberly C.;
    • Henriquez, Frances;
    • Curtis, James;
    • Gaspar, Miguel;
    • Nowak, Karolin;
    • Daza-Cajigal, Vanessa;
    • Kumararatne, Dinakantha;
    • Doffinger, Rainer;
    • Thrasher, Adrian J.;
    • Nejentsev, Sergey
    Publication type:
    Article
    42

    Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells.

    Published in:
    Nature Communications, 2016, v. 7, n. 7, p. 12175, doi. 10.1038/ncomms12175
    By:
    • Baptista, Marisa A. P.;
    • Keszei, Marton;
    • Oliveira, Mariana;
    • Sunahara, Karen K. S.;
    • Andersson, John;
    • Dahlberg, Carin I. M.;
    • Worth, Austen J.;
    • Liedén, Agne;
    • Kuo, I-Chun;
    • Wallin, Robert P. A.;
    • Snapper, Scott B.;
    • Eidsmo, Liv;
    • Scheynius, Annika;
    • Karlsson, Mikael C. I.;
    • Bouma, Gerben;
    • Burns, Siobhan O.;
    • Forsell, Mattias N. E.;
    • Thrasher, Adrian J.;
    • Nylén, Susanne;
    • Westerberg, Lisa S.
    Publication type:
    Article
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    Gene therapy: Is IL2RG oncogenic in T-cell development?

    Published in:
    Nature, 2006, v. 443, n. 7109, p. E5, doi. 10.1038/nature05218
    By:
    • Pike-Overzet, Karin;
    • de Ridder, Dick;
    • Weerkamp, Floor;
    • Baert, Miranda R. M.;
    • Verstegen, Monique M.;
    • Brugman, Martijn H.;
    • Howe, Steven J.;
    • Reinders, Marcel J. T.;
    • Thrasher, Adrian J.;
    • Wagemaker, Gerard;
    • van Dongen, Jacques J. M.;
    • Staal, Frank J. T.
    Publication type:
    Article
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    Gene therapy: X-SCID transgene leukaemogenicity.

    Published in:
    Nature, 2006, v. 443, n. 7109, p. E5, doi. 10.1038/nature05219
    By:
    • Thrasher, Adrian J.;
    • Gaspar, H. Bobby;
    • Baum, Christopher;
    • Modlich, Ute;
    • Schambach, Axel;
    • Candotti, Fabio;
    • Otsu, Makoto;
    • Sorrentino, Brian;
    • Scobie, Linda;
    • Cameron, Ewan;
    • Blyth, Karen;
    • Neil, Jim;
    • Abina, Salima Hacein-Bey;
    • Cavazzana-Calvo, Marina;
    • Fischer, Alain
    Publication type:
    Article
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    Lentiviral vectors can be used for full-length dystrophin gene therapy.

    Published in:
    Scientific Reports, 2017, p. 44775, doi. 10.1038/srep44775
    By:
    • Counsell, John R.;
    • Asgarian, Zeinab;
    • Meng, Jinhong;
    • Ferrer, Veronica;
    • Vink, Conrad A.;
    • Howe, Steven J.;
    • Waddington, Simon N.;
    • Thrasher, Adrian J.;
    • Muntoni, Francesco;
    • Morgan, Jennifer E.;
    • Danos, Olivier
    Publication type:
    Article
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