Works by Thorsteinsdottir, Unnur

Results: 49

Transcriptome-wide association study of multiple myeloma identifies candidate susceptibility genes.

Published in:

Human Genomics, 2019, v. 13, n. 1, p. N.PAG, doi. 10.1186/s40246-019-0231-5

By:

Went, Molly;
Kinnersley, Ben;
Sud, Amit;
Johnson, David C.;
Weinhold, Niels;
Försti, Asta;
van Duin, Mark;
Orlando, Giulia;
Mitchell, Jonathan S.;
Kuiper, Rowan;
Walker, Brian A.;
Gregory, Walter M.;
Hoffmann, Per;
Jackson, Graham H.;
Nöthen, Markus M.;
da Silva Filho, Miguel Inacio;
Thomsen, Hauke;
Broyl, Annemiek;
Davies, Faith E.;
Thorsteinsdottir, Unnur

Publication type:

Article

NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice.

Published in:

EMBO Journal, 2001, v. 20, n. 3, p. 350, doi. 10.1093/emboj/20.3.350

By:

Kroon, Evert;
Thorsteinsdottir, Unnur;
Mayotte, Nadine;
Nakamura, Takuro;
Sauvageau, Guy

Publication type:

Article

Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b.

Published in:

EMBO Journal, 1998, v. 17, n. 13, p. 3714, doi. 10.1093/emboj/17.13.3714

By:

Kroon, Evert;
Krosl, Jana;
Thorsteinsdottir, Unnur;
Baban, Soheyl;
Buchberg, Arthur M.;
Sauvageau, Guy

Publication type:

Article

Predicting the probability of death using proteomics.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02289-6

By:

Eiriksdottir, Thjodbjorg;
Ardal, Steinthor;
Jonsson, Benedikt A.;
Lund, Sigrun H.;
Ivarsdottir, Erna V.;
Norland, Kristjan;
Ferkingstad, Egil;
Stefansson, Hreinn;
Jonsdottir, Ingileif;
Holm, Hilma;
Rafnar, Thorunn;
Saemundsdottir, Jona;
Norddahl, Gudmundur L.;
Thorgeirsson, Gudmundur;
Gudbjartsson, Daniel F.;
Sulem, Patrick;
Thorsteinsdottir, Unnur;
Stefansson, Kari;
Ulfarsson, Magnus O.

Publication type:

Article

Support for involvement of the AHI1 locus in schizophrenia.

Published in:

European Journal of Human Genetics, 2007, v. 15, n. 9, p. 988, doi. 10.1038/sj.ejhg.5201848

By:

Ingason, Andres;
Sigmundsson, Thordur;
Steinberg, Stacy;
Sigurdsson, Engilbert;
Haraldsson, Magnus;
Magnusdottir, Brynja B.;
Frigge, Michael L.;
Kong, Augustine;
Gulcher, Jeffrey;
Thorsteinsdottir, Unnur;
Stefansson, Kari;
Petursson, Hannes;
Stefansson, Hreinn

Publication type:

Article

Several common variants modulate heart rate, PR interval and QRS duration.

Published in:

Nature Genetics, 2010, v. 42, n. 2, p. 117, doi. 10.1038/ng.511

By:

Holm, Hilma;
Gudbjartsson, Daniel F.;
Arnar, David O.;
Thorleifsson, Gudmar;
Thorgeirsson, Gudmundur;
Stefansdottir, Hrafnhildur;
Gudjonsson, Sigurjon A.;
Jonasdottir, Aslaug;
Mathiesen, Ellisiv B.;
Njølstad, Inger;
Nyrnes, Audhild;
Wilsgaard, Tom;
Hald, Erin M.;
Hveem, Kristian;
Stoltenberg, Camilla;
Løchen, Maja-Lisa;
Kong, Augustine;
Thorsteinsdottir, Unnur;
Stefansson, Kari

Publication type:

Article

New sequence variants associated with bone mineral density.

Published in:

Nature Genetics, 2009, v. 41, n. 1, p. 15, doi. 10.1038/ng.284

By:

Styrkarsdottir, Unnur;
Halldorsson, Bjarni V.;
Gretarsdottir, Solveig;
Gudbjartsson, Daniel F.;
Walters, G. Bragi;
Ingvarsson, Thorvaldur;
Jonsdottir, Thorbjorg;
Saemundsdottir, Jona;
Snorradóttir, Steinunn;
Center, Jacqueline R.;
Nguyen, Tuan V.;
Alexandersen, Peter;
Gulcher, Jeffrey R.;
Eisman, John A.;
Christiansen, Claus;
Sigurdsson, Gunnar;
Kong, Augustine;
Thorsteinsdottir, Unnur;
Stefansson, Kari

Publication type:

Article

Male-pattern baldness susceptibility locus at 20p11.

Published in:

Nature Genetics, 2008, v. 40, n. 11, p. 1282, doi. 10.1038/ng.255

By:

Richards, J Brent;
Yuan, Xin;
Geller, Frank;
Waterworth, Dawn;
Bataille, Veronique;
Glass, Daniel;
Song, Kijoung;
Waeber, Gerard;
Vollenweider, Peter;
Aben, Katja K H;
Kiemeney, Lambertus A;
Walters, Bragi;
Soranzo, Nicole;
Thorsteinsdottir, Unnur;
Kong, Augustine;
Rafnar, Thorunn;
Deloukas, Panos;
Sulem, Patrick;
Stefansson, Hreinn;
Stefansson, Kari

Publication type:

Article

A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction.

Published in:

Nature Genetics, 2006, v. 38, n. 1, p. 68, doi. 10.1038/ng1692

By:

Helgadottir, Anna;
Manolescu, Andrei;
Helgason, Agnar;
Thorleifsson, Gudmar;
Thorsteinsdottir, Unnur;
Gudbjartsson, Daniel F;
Gretarsdottir, Solveig;
Magnusson, Kristinn P;
Gudmundsson, Gudmundur;
Hicks, Andrew;
Jonsson, Thorlakur;
Grant, Struan F A;
Sainz, Jesus;
O'Brien, Stephen J;
Sveinbjornsdottir, Sigurlaug;
Valdimarsson, Einar M;
Matthiasson, Stefan E;
Levey, Allan I;
Abramson, Jerome L;
Reilly, Murdach P

Publication type:

Article

The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke.

Published in:

Nature Genetics, 2004, v. 36, n. 3, p. 233, doi. 10.1038/ng1311

By:

Helgadottir, Anna;
Manolescu, Andrei;
Thorleifsson, Gudmar;
Gretarsdottir, Solveig;
Jonsdottir, Helga;
Thorsteinsdottir, Unnur;
Samani, Nilesh J.;
Gudmundsson, Gudmundur;
A. Grant, Struan F.;
Thorgeirsson, Gudmundur;
Sveinbjornsdottir, Sigurlaug;
Valdimarsson, Einar M.;
Matthiasson, Stefan E.;
Johannsson, Halldor;
Gudmundsdottir, Olof;
Gurney, Mark E.;
Sainz, Jesus;
Thorhallsdottir, Margret;
Andresdottir, Margret;
Frigge, Michael L.

Publication type:

Article

Association of Variants at UMOD with Chronic Kidney Disease and Kidney Stones-Role of Age and Comorbid Diseases.

Published in:

PLoS Genetics, 2010, v. 6, n. 7, p. 1, doi. 10.1371/journal.pgen.1001039

By:

Gudbjartsson, Daniel F.;
Holm, Hilma;
Indridason, Olafur S.;
Thorleifsson, Gudmar;
Edvardsson, Vidar;
Sulem, Patrick;
de Vegt, Femmie;
d'Ancona, Frank C. H.;
den Heijer, Martin;
Franzson, Leifur;
Rafnar, Thorunn;
Kristjansson, Kristleifur;
Bjornsdottir, Unnur S.;
Eyjolfsson, Gudmundur I.;
Kiemeney, Lambertus A.;
Kong, Augustine;
Palsson, Runolfur;
Thorsteinsdottir, Unnur;
Stefansson, Kari

Publication type:

Article

A Drastic Reduction in the Life Span of Cystatin C L68Q Carriers Due to Life-Style Changes during the Last Two Centuries.

Published in:

PLoS Genetics, 2008, v. 4, n. 6, p. 1, doi. 10.1371/journal.pgen.1000099

By:

Palsdottir, Astridur;
Helgason, Agnar;
Palsson, Snaebjorn;
Bjornsson, Hans Tomas;
Bragason, Birkir Thor;
Gretarsdottir, Solveig;
Thorsteinsdottir, Unnur;
Olafsson, Elias;
Stefansson, Kari

Publication type:

Article

The Association of a SNP Upstream of INSIG2 with Body Mass Index is Reproduced in Several but Not All Cohorts.

Published in:

PLoS Genetics, 2007, v. 3, n. 4, p. e61, doi. 10.1371/journal.pgen.0030061

By:

Lyon, Helen N.;
Emilsson, Valur;
Hinney, Anke;
Heid, Iris M.;
Lasky-Su, Jessica;
Xiaofeng Zhu;
Thorleifsson, Gudmar;
Gunnarsdottir, Steinunn;
Walters, G. Bragi;
Thorsteinsdottir, Unnur;
Kong, Augustine;
Gulcher, Jeffrey;
Thuy Trang Nguyen;
Scherag, André;
Pfeufer, Arne;
Meitinger, Thomas;
Brönner, Günter;
Rief, Winfried;
Soto-Quiros, Manuel E.;
Avila, Lydiana

Publication type:

Article

The BARD1 Cys557Ser variant and breast cancer risk in Iceland.

Published in:

2006

By:

Stacey, Simon N.;
Sulem, Patrick;
Johannsson, Oskar T.;
Helgason, Agnar;
Gudmundsson, Julius;
Kostic, Jelena P.;
Kristjansson, Kristleifur;
Jonsdottir, Thora;
Sigurdsson, Helgi;
Hrafnkelsson, Jon;
Johannsson, Jakob;
Sveinsson, Thorarinn;
Myrdal, Gardar;
Grimsson, Hlynur Niels;
Bergthorsson, Jon T.;
Amundadottir, Laufey T.;
Gulcher, Jeffrey R.;
Thorsteinsdottir, Unnur;
Kong, Augustine;
Stefansson, Kari

Publication type:

journal article

Familial Risk of Lung Carcinoma in the Icelandic Population.

Published in:

JAMA: Journal of the American Medical Association, 2004, v. 292, n. 24, p. 2977, doi. 10.1001/jama.292.24.2977

By:

Jonsson, Steinn;
Thorsteinsdottir, Unnur;
Gudbjartsson, Daniel F.;
Jonsson, Hjortur H.;
Kristjansson, Kristleifur;
Arnason, Sigurdur;
Gudnason, Vilmundur;
Isaksson, Helgi J.;
Hallgrimsson, Jonas;
Gulcher, Jeffrey R.;
Amundadottir, Laufey T.;
Kong, Augustine;
Stefansson, Kari

Publication type:

Article

Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans.

Published in:

Cardiovascular Research, 2011, v. 90, n. 1, p. 18

By:

Michel, Jean-Baptiste;
Martin-Ventura, José-Luis;
Egido, Jesus;
Sakalihasan, Natzi;
Treska, Vladislav;
Lindholt, Jes;
Allaire, Eric;
Thorsteinsdottir, Unnur;
Cockerill, Gillian;
Swedenborg, Jesper

Publication type:

Article

Identification of a large set of rare complete human knockouts.

Published in:

Nature Genetics, 2015, v. 47, n. 5, p. 448, doi. 10.1038/ng.3243

By:

Sulem, Patrick;
Oddson, Asmundur;
Stefansson, Hreinn;
Gudjonsson, Sigurjon A;
Zink, Florian;
Hjartarson, Eirikur;
Sigurdsson, Gunnar Th;
Jonasdottir, Adalbjorg;
Jonasdottir, Aslaug;
Sigurdsson, Asgeir;
Magnusson, Olafur Th;
Masson, Gisli;
Helgason, Hannes;
Kong, Augustine;
Gudbjartsson, Daniel F;
Helgason, Agnar;
Holm, Hilma;
Thorsteinsdottir, Unnur;
Stefansson, Kari

Publication type:

Article

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma.

Published in:

Nature Genetics, 2014, v. 46, n. 10, p. 1126, doi. 10.1038/ng.3087

By:

Hysi, Pirro G;
Hammond, Christopher J;
Höhn, René;
Mirshahi, Alireza;
Pfeiffer, Norbert;
Venturini, Cristina;
Ramdas, Wishal D;
Vingerling, Johannes R;
Klaver, Caroline C W;
Thorleifsson, Gudmar;
Thorsteinsdottir, Unnur;
Stefansson, Kari;
Vithana, Eranga;
Khor, Chiea-Chuen;
Stefansson, Arni B;
Liao, Jiemin;
Haines, Jonathan L;
Amin, Najaf;
Karssen, Lennart C;
Iglesias, Adriana I

Publication type:

Article

Common and low-frequency variants associated with genome-wide recombination rate.

Published in:

Nature Genetics, 2014, v. 46, n. 1, p. 11, doi. 10.1038/ng.2833

By:

Kong, Augustine;
Thorleifsson, Gudmar;
Frigge, Michael L;
Masson, Gisli;
Gudbjartsson, Daniel F;
Villemoes, Rasmus;
Magnusdottir, Erna;
Olafsdottir, Stefania B;
Thorsteinsdottir, Unnur;
Stefansson, Kari

Publication type:

Article

Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization.

Published in:

Nature Genetics, 2013, v. 45, n. 8, p. 902, doi. 10.1038/ng.2694

By:

Bønnelykke, Klaus;
Matheson, Melanie C;
Pers, Tune H;
Granell, Raquel;
Strachan, David P;
Alves, Alexessander Couto;
Linneberg, Allan;
Curtin, John A;
Warrington, Nicole M;
Standl, Marie;
Kerkhof, Marjan;
Jonsdottir, Ingileif;
Bukvic, Blazenka K;
Kaakinen, Marika;
Sleimann, Patrick;
Thorleifsson, Gudmar;
Thorsteinsdottir, Unnur;
Schramm, Katharina;
Baltic, Svetlana;
Kreiner-Møller, Eskil

Publication type:

Article

Cartilage Acidic Protein 1 in Plasma Associates With Prevalent Osteoarthritis and Predicts Future Risk as Well as Progression to Joint Replacements: Results From the UK Biobank Resource.

Published in:

Arthritis & Rheumatology, 2023, v. 75, n. 4, p. 544, doi. 10.1002/art.42376

By:

Styrkarsdottir, Unnur;
Lund, Sigrun H.;
Thorleifsson, Gudmar;
Saevarsdottir, Saedis;
Gudbjartsson, Daniel F.;
Thorsteinsdottir, Unnur;
Stefansson, Kari

Publication type:

Article

The CRTAC1 Protein in Plasma Is Associated With Osteoarthritis and Predicts Progression to Joint Replacement: A Large‐Scale Proteomics Scan in Iceland.

Published in:

Arthritis & Rheumatology, 2021, v. 73, n. 11, p. 2025, doi. 10.1002/art.41793

By:

Styrkarsdottir, Unnur;
Lund, Sigrun H.;
Saevarsdottir, Saedis;
Magnusson, Magnus I.;
Gunnarsdottir, Kristbjorg;
Norddahl, Gudmundur L.;
Frigge, Michael L.;
Ivarsdottir, Erna V.;
Bjornsdottir, Gyda;
Holm, Hilma;
Thorgeirsson, Gudmundur;
Rafnar, Thorunn;
Jonsdottir, Ingileif;
Ingvarsson, Thorvaldur;
Jonsson, Helgi;
Sulem, Patrick;
Thorsteinsdottir, Unnur;
Gudbjartsson, Daniel;
Stefansson, Kari

Publication type:

Article

Effect of booster vaccination against Delta and Omicron SARS-CoV-2 variants in Iceland.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33076-4

By:

Norddahl, Gudmundur L.;
Melsted, Pall;
Gunnarsdottir, Kristbjorg;
Halldorsson, Gisli H.;
Olafsdottir, Thorunn A.;
Gylfason, Arnaldur;
Kristjansson, Mar;
Magnusson, Olafur T.;
Sulem, Patrick;
Gudbjartsson, Daniel F.;
Thorsteinsdottir, Unnur;
Jonsdottir, Ingileif;
Stefansson, Kari

Publication type:

Article

Multi-nucleotide de novo Mutations in Humans.

Published in:

PLoS Genetics, 2016, v. 12, n. 11, p. 1, doi. 10.1371/journal.pgen.1006315

By:

Besenbacher, Søren;
Sulem, Patrick;
Helgason, Agnar;
Helgason, Hannes;
Kristjansson, Helgi;
Jonasdottir, Aslaug;
Jonasdottir, Adalbjorg;
Magnusson, Olafur Th.;
Thorsteinsdottir, Unnur;
Masson, Gisli;
Kong, Augustine;
Gudbjartsson, Daniel F.;
Stefansson, Kari

Publication type:

Article

Sequence variants affecting the genome-wide rate of germline microsatellite mutations.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39547-6

By:

Kristmundsdottir, Snaedis;
Jonsson, Hakon;
Hardarson, Marteinn T.;
Palsson, Gunnar;
Beyter, Doruk;
Eggertsson, Hannes P.;
Gylfason, Arnaldur;
Sveinbjornsson, Gardar;
Holley, Guillaume;
Stefansson, Olafur A.;
Halldorsson, Gisli H.;
Olafsson, Sigurgeir;
Arnadottir, Gudny. A.;
Olason, Pall I.;
Eiriksson, Ogmundur;
Masson, Gisli;
Thorsteinsdottir, Unnur;
Rafnar, Thorunn;
Sulem, Patrick;
Helgason, Agnar

Publication type:

Article

Interstitial deletions including chromosome 3 common eliminated region 1 (C3CER1) prevail in human solid tumors from 10 different tissues.

Published in:

Genes, Chromosomes & Cancer, 2004, v. 41, n. 3, p. 232

By:

Thorgunnur Eyfjord Petursdottir;
Unnur Thorsteinsdottir;
Jon Gunnlaugur Jonasson;
Pall Helgi Moller;
Chen Huiping;
Johannes Bjornsson;
Valgardur Egilsson;
Stefan Imreh;
Sigurdur Ingvarsson

Publication type:

Article

Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis.

Published in:

Nature Communications, 2017, v. 8, n. 6, p. 15789, doi. 10.1038/ncomms15789

By:

Sigurdsson, Snaevar;
Alexandersson, Kristjan F.;
Sulem, Patrick;
Feenstra, Bjarke;
Gudmundsdottir, Steinunn;
Halldorsson, Gisli H.;
Olafsson, Sigurgeir;
Sigurdsson, Asgeir;
Rafnar, Thorunn;
Thorgeirsson, Thorgeir;
Sørensen, Erik;
Nordholm-Carstensen, Andreas;
Burcharth, Jakob;
Andersen, Jens;
Jørgensen, Henrik Stig;
Possfelt-Møller, Emma;
Ullum, Henrik;
Thorleifsson, Gudmar;
Masson, Gisli;
Thorsteinsdottir, Unnur

Publication type:

Article

Erratum: A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.

Published in:

Nature Communications, 2016, v. 7, n. 9, p. 12869, doi. 10.1038/ncomms12869

By:

Rivas, Manuel A.;
Graham, Daniel;
Sulem, Patrick;
Stevens, Christine;
Desch, A. Nicole;
Goyette, Philippe;
Gudbjartsson, Daniel;
Jonsdottir, Ingileif;
Thorsteinsdottir, Unnur;
Degenhardt, Frauke;
Mucha, Sören;
Kurki, Mitja I.;
Li, Dalin;
D'Amato, Mauro;
Annese, Vito;
Vermeire, Severine;
Weersma, Rinse K.;
Halfvarson, Jonas;
Paavola-Sakki, Paulina;
Lappalainen, Maarit

Publication type:

Article

A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.

Published in:

Nature Communications, 2016, v. 7, n. 8, p. 12342, doi. 10.1038/ncomms12342

By:

Rivas, Manuel A.;
Graham, Daniel;
Sulem, Patrick;
Stevens, Christine;
Desch, A. Nicole;
Goyette, Philippe;
Gudbjartsson, Daniel;
Jonsdottir, Ingileif;
Thorsteinsdottir, Unnur;
Degenhardt, Frauke;
Mucha, Sören;
Kurki, Mitja I.;
Li, Dalin;
D'Amato, Mauro;
Annese, Vito;
Vermeire, Severine;
Weersma, Rinse K.;
Halfvarson, Jonas;
Paavola-Sakki, Paulina;
Lappalainen, Maarit

Publication type:

Article

Common variants upstream of KDR encoding VEGFR2 and in TTC39B associate with endometriosis.

Published in:

Nature Communications, 2016, v. 7, n. 7, p. 12350, doi. 10.1038/ncomms12350

By:

Steinthorsdottir, Valgerdur;
Thorleifsson, Gudmar;
Aradottir, Kristrun;
Feenstra, Bjarke;
Sigurdsson, Asgeir;
Stefansdottir, Lilja;
Kristinsdottir, Anna M.;
Zink, Florian;
Halldorsson, Gisli H.;
Munk Nielsen, Nete;
Geller, Frank;
Melbye, Mads;
Gudbjartsson, Daniel F.;
Geirsson, Reynir T.;
Thorsteinsdottir, Unnur;
Stefansson, Kari

Publication type:

Article

Common and rare variants associated with kidney stones and biochemical traits.

Published in:

Nature Communications, 2015, v. 6, n. 8, p. 7975, doi. 10.1038/ncomms8975

By:

Oddsson, Asmundur;
Sulem, Patrick;
Helgason, Hannes;
Edvardsson, Vidar O.;
Thorleifsson, Gudmar;
Sveinbjörnsson, Gardar;
Haraldsdottir, Eik;
Eyjolfsson, Gudmundur I.;
Sigurdardottir, Olof;
Olafsson, Isleifur;
Masson, Gisli;
Holm, Hilma;
Gudbjartsson, Daniel F.;
Thorsteinsdottir, Unnur;
Indridason, Olafur S.;
Palsson, Runolfur;
Stefansson, Kari

Publication type:

Article

Histopathology and levels of proteins in plasma associate with survival after colorectal cancer diagnosis.

Published in:

British Journal of Cancer, 2023, v. 129, n. 7, p. 1142, doi. 10.1038/s41416-023-02374-z

By:

Magnusson, Magnus I.;
Agnarsson, Bjarni A.;
Jonasson, Jon G.;
Tryggvason, Thordur;
Aeffner, Famke;
le Roux, Louise;
Magnusdottir, Droplaug N.;
Gunnarsdottir, Helga S.;
Alexíusdóttir, Kristín K.;
Gunnarsdottir, Kristbjorg;
Söebech, Emilia;
Runarsdottir, Hjaltey;
Jonsdottir, Erna M.;
Kristinsdottir, Bjarney S.;
Olafsson, Sigurgeir;
Knutsdottir, Hildur;
Thorsteinsdottir, Unnur;
Ulfarsson, Magnus O.;
Gudbjartsson, Daniel F.;
Saemundsdottir, Jona

Publication type:

Article

Cancer as a Complex Phenotype: Pattern of Cancer Distribution within and beyond the Nuclear Family.

Published in:

PLoS Medicine, 2004, v. 1, n. 3, p. 229, doi. 10.1371/journal.pmed.0010065

By:

Amundadottir, Laufey T.;
Thorvaldsson, Sverrir;
Gudbjartsson, Daniel F.;
Sulem, Patrick;
Kristjansson, Kristleifur;
Arnason, Sigurdur;
Gulcher, Jeffrey R.;
Bjornsson, Johannes;
Kong, Augustine;
Thorsteinsdottir, Unnur;
Stefansson, Kari

Publication type:

Article

Two Rare Mutations in the COL1A2 Gene Associate With Low Bone Mineral Density and Fractures in Iceland.

Published in:

Journal of Bone & Mineral Research, 2016, v. 31, n. 1, p. 173, doi. 10.1002/jbmr.2604

By:

Styrkarsdottir, Unnur;
Thorleifsson, Gudmar;
Eiriksdottir, Berglind;
Gudjonsson, Sigurjon A.;
Ingvarsson, Thorvaldur;
Center, Jacqueline R.;
Nguyen, Tuan V.;
Eisman, John A.;
Christiansen, Claus;
Thorsteinsdottir, Unnur;
Sigurdsson, Gunnar;
Stefansson, Kari

Publication type:

Article

Association Analysis of 29,956 Individuals Confirms That a Low-Frequency Variant at CCND2 Halves the Risk of Type 2 Diabetes by Enhancing Insulin Secretion.

Published in:

Diabetes, 2015, v. 64, n. 6, p. 2279, doi. 10.2337/db14-1456

By:

Yaghootkar, Hanieh;
Stancáková, Alena;
Freathy, Rachel M.;
Vangipurapu, Jagadish;
Weedon, Michael N.;
Weijia Xie;
Wood, Andrew R.;
Ferrannini, Ele;
Mari, Andrea;
Ring, Susan M.;
Lawlor, Debbie A.;
Smith, George Davey;
Jørgensen, Torben;
Hansen, Torben;
Pedersen, Oluf;
Steinthorsdottir, Valgerdur;
Guðbjartsson, Daniel F.;
Thorleifsson, Gudmar;
Thorsteinsdottir, Unnur;
Stefansson, Kari

Publication type:

Article

Rare Genomic Structural Variants in Complex Disease: Lessons from the Replication of Associations with Obesity.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058048

By:

Walters, Robin G.;
Coin, Lachlan J. M.;
Ruokonen, Aimo;
de Smith, Adam J.;
El-Sayed Moustafa, Julia S.;
Jacquemont, Sebastien;
Elliott, Paul;
Esko, Tõnu;
Hartikainen, Anna-Liisa;
Laitinen, Jaana;
Männik, Katrin;
Martinet, Danielle;
Meyre, David;
Nauck, Matthias;
Schurmann, Claudia;
Sladek, Rob;
Thorleifsson, Gudmar;
Thorsteinsdóttir, Unnur;
Valsesia, Armand;
Waeber, Gerard

Publication type:

Article

Rate of de novo mutations and the importance of father's age to disease risk.

Published in:

Nature, 2012, v. 488, n. 7412, p. 471, doi. 10.1038/nature11396

By:

Kong, Augustine;
Frigge, Michael L.;
Masson, Gisli;
Besenbacher, Soren;
Sulem, Patrick;
Magnusson, Gisli;
Gudjonsson, Sigurjon A.;
Sigurdsson, Asgeir;
Jonasdottir, Aslaug;
Jonasdottir, Adalbjorg;
Wong, Wendy S. W.;
Sigurdsson, Gunnar;
Walters, G. Bragi;
Steinberg, Stacy;
Helgason, Hannes;
Thorleifsson, Gudmar;
Gudbjartsson, Daniel F.;
Helgason, Agnar;
Magnusson, Olafur Th.;
Thorsteinsdottir, Unnur

Publication type:

Article

Fine-scale recombination rate differences between sexes, populations and individuals.

Published in:

Nature, 2010, v. 467, n. 7319, p. 1099, doi. 10.1038/nature09525

By:

Kong, Augustine;
Thorleifsson, Gudmar;
Gudbjartsson, Daniel F.;
Masson, Gisli;
Sigurdsson, Asgeir;
Jonasdottir, Aslaug;
Walters, G. Bragi;
Jonasdottir, Adalbjorg;
Gylfason, Arnaldur;
Kristinsson, Kari Th.;
Gudjonsson, Sigurjon A.;
Frigge, Michael L.;
Helgason, Agnar;
Thorsteinsdottir, Unnur;
Stefansson, Kari

Publication type:

Article

Comment on "Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics".

Published in:

Science Translational Medicine, 2021, v. 13, n. 622, p. 1, doi. 10.1126/scitranslmed.abe8497

By:

Hólm, Hilma;
Sulem, Patrick;
Tragante, Vinicius;
Thorsteinsdottir, Unnur;
Gudbjartsson, Daniel F.;
Stefansson, Kari

Publication type:

Article

Polygenic risk score for ACE-inhibitor-associated cough based on the discovery of new genetic loci.

Published in:

European Heart Journal, 2022, v. 43, n. 45, p. 4707, doi. 10.1093/eurheartj/ehac322

By:

Ghouse, Jonas;
Tragante, Vinicius;
Muhammad, Ayesha;
Ahlberg, Gustav;
Skov, Morten W;
Roden, Dan M;
Jonsdottir, Ingileif;
Andreasen, Laura;
Lundegaard, Pia Rengtved;
Trudsø, Linea C;
Banasik, Karina;
Brunak, Søren;
Ostrowski, Sisse R;
consortium, eMERGE;
Torp-Pedersen, Christian;
Pedersen, Ole V;
Sørensen, Erik;
Køber, Lars;
Iversen, Kasper;
Thorsteinsdottir, Unnur

Publication type:

Article

Protolichesterinic Acid, Isolated from the Lichen Cetraria islandica, Reduces LRRC8A Expression and Volume-Sensitive Release of Organic Osmolytes in Human Lung Epithelial Cancer Cells.

Published in:

2016

By:

Thorsteinsdottir, Unnur Arna;
Thorsteinsdottir, Margret;
Lambert, Ian Henry

Publication type:

journal article

Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locus.

Published in:

Human Molecular Genetics, 2017, v. 26, n. 19, p. 3850, doi. 10.1093/hmg/ddx285

By:

Hackinger, Sophie;
Trajanoska, Katerina;
Styrkarsdottir, Unnur;
Zengini, Eleni;
Steinberg, Julia;
Ritchie, Graham R. S.;
Hatzikotoulas, Konstantinos;
Gilly, Arthur;
Evangelou, Evangelos;
Kemp, John P.;
Evans, David;
Ingvarsson, Thorvaldur;
Jonsson, Helgi;
Thorsteinsdottir, Unnur;
Stefansson, Kari;
McCaskie, Andrew W.;
Brooks, Roger A.;
Wilkinson, Jeremy M.;
Rivadeneira, Fernando;
Zeggini, Eleftheria

Publication type:

Article

Rare mutations associating with serum creatinine and chronic kidney disease.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 25, p. 6935, doi. 10.1093/hmg/ddu399

By:

Sveinbjornsson, Gardar;
Mikaelsdottir, Evgenia;
Palsson, Runolfur;
Indridason, Olafur S.;
Holm, Hilma;
Jonasdottir, Aslaug;
Helgason, Agnar;
Sigurdsson, Snaevar;
Jonasdottir, Adalbjorg;
Sigurdsson, Asgeir;
Eyjolfsson, Gudmundur Ingi;
Sigurdardottir, Olof;
Magnusson, Olafur Th.;
Kong, Augustine;
Masson, Gisli;
Sulem, Patrick;
Olafsson, Isleifur;
Thorsteinsdottir, Unnur;
Gudbjartsson, Daniel F.;
Stefansson, Kari

Publication type:

Article

Rare mutations associating with serum creatinine and chronic kidney disease.

Published in:

Human Molecular Genetics, 2012, v. 21, n. 25, p. 1, doi. 10.1093/hmg/ddu399

By:

Sveinbjornsson, Gardar;
Mikaelsdottir, Evgenia;
Palsson, Runolfur;
Indridason, Olafur S.;
Holm, Hilma;
Jonasdottir, Aslaug;
Helgason, Agnar;
Sigurdsson, Snaevar;
Jonasdottir, Adalbjorg;
Sigurdsson, Asgeir;
Eyjolfsson, Gudmundur Ingi;
Sigurdardottir, Olof;
Magnusson, Olafur Th.;
Kong, Augustine;
Masson, Gisli;
Sulem, Patrick;
Olafsson, Isleifur;
Thorsteinsdottir, Unnur;
Gudbjartsson, Daniel F.;
Stefansson, Kari

Publication type:

Article

Sequence variants with large effects on cardiac electrophysiology and disease.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12682-9

By:

Norland, Kristjan;
Sveinbjornsson, Gardar;
Thorolfsdottir, Rosa B.;
Davidsson, Olafur B.;
Tragante, Vinicius;
Rajamani, Sridharan;
Helgadottir, Anna;
Gretarsdottir, Solveig;
van Setten, Jessica;
Asselbergs, Folkert W.;
Sverrisson, Jon Th.;
Stephensen, Sigurdur S.;
Oskarsson, Gylfi;
Sigurdsson, Emil L.;
Andersen, Karl;
Danielsen, Ragnar;
Thorgeirsson, Gudmundur;
Thorsteinsdottir, Unnur;
Arnar, David O.;
Sulem, Patrick

Publication type:

Article

Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-09304-9

By:

Ivarsdottir, Erna V.;
Benonisdottir, Stefania;
Thorleifsson, Gudmar;
Sulem, Patrick;
Oddsson, Asmundur;
Styrkarsdottir, Unnur;
Kristmundsdottir, Snaedis;
Arnadottir, Gudny A.;
Thorgeirsson, Gudmundur;
Jonsdottir, Ingileif;
Zoega, Gunnar M.;
Thorsteinsdottir, Unnur;
Gudbjartsson, Daniel F.;
Jonasson, Fridbert;
Holm, Hilma;
Stefansson, Kari

Publication type:

Article

Design of experiments for development and optimization of a liquid chromatography coupled to tandem mass spectrometry bioanalytical assay.

Published in:

Journal of Mass Spectrometry, 2021, v. 56, n. 9, p. 1, doi. 10.1002/jms.4566

By:

Thorsteinsdóttir, Unnur Arna;
Thorsteinsdóttir, Margrét

Publication type:

Article

Design of experiments for development and optimization of a liquid chromatography coupled to tandem mass spectrometry bioanalytical assay.

Published in:

Journal of Mass Spectrometry, 2021, v. 56, n. 9, p. 1, doi. 10.1002/jms.4566

By:

Thorsteinsdóttir, Unnur Arna;
Thorsteinsdóttir, Margrét

Publication type:

Article

Compound heterozygous mutations in UBA5 causing early-onset epileptic encephalopathy in two sisters.

Published in:

2017

By:

Arnadottir, Gudny A.;
Jensson, Brynjar O.;
Marelsson, Sigurdur E.;
Sulem, Gerald;
Oddsson, Asmundur;
Kristjansson, Ragnar P.;
Benonisdottir, Stefania;
Gudjonsson, Sigurjon A.;
Masson, Gisli;
Thorisson, Gudmundur A.;
Saemundsdottir, Jona;
Magnusson, Olafur Th.;
Jonasdottir, Adalbjorg;
Jonasdottir, Aslaug;
Sigurdsson, Asgeir;
Gudbjartsson, Daniel F.;
Thorsteinsdottir, Unnur;
Arngrimsson, Reynir;
Sulem, Patrick;
Stefansson, Kari

Publication type:

Case Study