Found: 49

Select item for more details and to access through your institution.

  • Histopathology and levels of proteins in plasma associate with survival after colorectal cancer diagnosis.

    Published in:
    British Journal of Cancer, 2023, v. 129, n. 7, p. 1142, doi. 10.1038/s41416-023-02374-z
    By:
    • Magnusson, Magnus I.;
    • Agnarsson, Bjarni A.;
    • Jonasson, Jon G.;
    • Tryggvason, Thordur;
    • Aeffner, Famke;
    • le Roux, Louise;
    • Magnusdottir, Droplaug N.;
    • Gunnarsdottir, Helga S.;
    • Alexíusdóttir, Kristín K.;
    • Gunnarsdottir, Kristbjorg;
    • Söebech, Emilia;
    • Runarsdottir, Hjaltey;
    • Jonsdottir, Erna M.;
    • Kristinsdottir, Bjarney S.;
    • Olafsson, Sigurgeir;
    • Knutsdottir, Hildur;
    • Thorsteinsdottir, Unnur;
    • Ulfarsson, Magnus O.;
    • Gudbjartsson, Daniel F.;
    • Saemundsdottir, Jona
    Publication type:
    Article

  • Sequence variants affecting the genome-wide rate of germline microsatellite mutations.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39547-6
    By:
    • Kristmundsdottir, Snaedis;
    • Jonsson, Hakon;
    • Hardarson, Marteinn T.;
    • Palsson, Gunnar;
    • Beyter, Doruk;
    • Eggertsson, Hannes P.;
    • Gylfason, Arnaldur;
    • Sveinbjornsson, Gardar;
    • Holley, Guillaume;
    • Stefansson, Olafur A.;
    • Halldorsson, Gisli H.;
    • Olafsson, Sigurgeir;
    • Arnadottir, Gudny. A.;
    • Olason, Pall I.;
    • Eiriksson, Ogmundur;
    • Masson, Gisli;
    • Thorsteinsdottir, Unnur;
    • Rafnar, Thorunn;
    • Sulem, Patrick;
    • Helgason, Agnar
    Publication type:
    Article

  • Cartilage Acidic Protein 1 in Plasma Associates With Prevalent Osteoarthritis and Predicts Future Risk as Well as Progression to Joint Replacements: Results From the UK Biobank Resource.

    Published in:
    Arthritis & Rheumatology, 2023, v. 75, n. 4, p. 544, doi. 10.1002/art.42376
    By:
    • Styrkarsdottir, Unnur;
    • Lund, Sigrun H.;
    • Thorleifsson, Gudmar;
    • Saevarsdottir, Saedis;
    • Gudbjartsson, Daniel F.;
    • Thorsteinsdottir, Unnur;
    • Stefansson, Kari
    Publication type:
    Article

  • Polygenic risk score for ACE-inhibitor-associated cough based on the discovery of new genetic loci.

    Published in:
    European Heart Journal, 2022, v. 43, n. 45, p. 4707, doi. 10.1093/eurheartj/ehac322
    By:
    • Ghouse, Jonas;
    • Tragante, Vinicius;
    • Muhammad, Ayesha;
    • Ahlberg, Gustav;
    • Skov, Morten W;
    • Roden, Dan M;
    • Jonsdottir, Ingileif;
    • Andreasen, Laura;
    • Lundegaard, Pia Rengtved;
    • Trudsø, Linea C;
    • Banasik, Karina;
    • Brunak, Søren;
    • Ostrowski, Sisse R;
    • consortium, eMERGE;
    • Torp-Pedersen, Christian;
    • Pedersen, Ole V;
    • Sørensen, Erik;
    • Køber, Lars;
    • Iversen, Kasper;
    • Thorsteinsdottir, Unnur
    Publication type:
    Article

  • Effect of booster vaccination against Delta and Omicron SARS-CoV-2 variants in Iceland.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33076-4
    By:
    • Norddahl, Gudmundur L.;
    • Melsted, Pall;
    • Gunnarsdottir, Kristbjorg;
    • Halldorsson, Gisli H.;
    • Olafsdottir, Thorunn A.;
    • Gylfason, Arnaldur;
    • Kristjansson, Mar;
    • Magnusson, Olafur T.;
    • Sulem, Patrick;
    • Gudbjartsson, Daniel F.;
    • Thorsteinsdottir, Unnur;
    • Jonsdottir, Ingileif;
    • Stefansson, Kari
    Publication type:
    Article

  • Comment on "Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics".

    Published in:
    Science Translational Medicine, 2021, v. 13, n. 622, p. 1, doi. 10.1126/scitranslmed.abe8497
    By:
    • Hólm, Hilma;
    • Sulem, Patrick;
    • Tragante, Vinicius;
    • Thorsteinsdottir, Unnur;
    • Gudbjartsson, Daniel F.;
    • Stefansson, Kari
    Publication type:
    Article

  • The CRTAC1 Protein in Plasma Is Associated With Osteoarthritis and Predicts Progression to Joint Replacement: A Large‐Scale Proteomics Scan in Iceland.

    Published in:
    Arthritis & Rheumatology, 2021, v. 73, n. 11, p. 2025, doi. 10.1002/art.41793
    By:
    • Styrkarsdottir, Unnur;
    • Lund, Sigrun H.;
    • Saevarsdottir, Saedis;
    • Magnusson, Magnus I.;
    • Gunnarsdottir, Kristbjorg;
    • Norddahl, Gudmundur L.;
    • Frigge, Michael L.;
    • Ivarsdottir, Erna V.;
    • Bjornsdottir, Gyda;
    • Holm, Hilma;
    • Thorgeirsson, Gudmundur;
    • Rafnar, Thorunn;
    • Jonsdottir, Ingileif;
    • Ingvarsson, Thorvaldur;
    • Jonsson, Helgi;
    • Sulem, Patrick;
    • Thorsteinsdottir, Unnur;
    • Gudbjartsson, Daniel;
    • Stefansson, Kari
    Publication type:
    Article

  • Design of experiments for development and optimization of a liquid chromatography coupled to tandem mass spectrometry bioanalytical assay.

    Published in:
    Journal of Mass Spectrometry, 2021, v. 56, n. 9, p. 1, doi. 10.1002/jms.4566
    By:
    • Thorsteinsdóttir, Unnur Arna;
    • Thorsteinsdóttir, Margrét
    Publication type:
    Article

  • Design of experiments for development and optimization of a liquid chromatography coupled to tandem mass spectrometry bioanalytical assay.

    Published in:
    Journal of Mass Spectrometry, 2021, v. 56, n. 9, p. 1, doi. 10.1002/jms.4566
    By:
    • Thorsteinsdóttir, Unnur Arna;
    • Thorsteinsdóttir, Margrét
    Publication type:
    Article

  • Predicting the probability of death using proteomics.

    Published in:
    Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02289-6
    By:
    • Eiriksdottir, Thjodbjorg;
    • Ardal, Steinthor;
    • Jonsson, Benedikt A.;
    • Lund, Sigrun H.;
    • Ivarsdottir, Erna V.;
    • Norland, Kristjan;
    • Ferkingstad, Egil;
    • Stefansson, Hreinn;
    • Jonsdottir, Ingileif;
    • Holm, Hilma;
    • Rafnar, Thorunn;
    • Saemundsdottir, Jona;
    • Norddahl, Gudmundur L.;
    • Thorgeirsson, Gudmundur;
    • Gudbjartsson, Daniel F.;
    • Sulem, Patrick;
    • Thorsteinsdottir, Unnur;
    • Stefansson, Kari;
    • Ulfarsson, Magnus O.
    Publication type:
    Article

  • Sequence variants with large effects on cardiac electrophysiology and disease.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12682-9
    By:
    • Norland, Kristjan;
    • Sveinbjornsson, Gardar;
    • Thorolfsdottir, Rosa B.;
    • Davidsson, Olafur B.;
    • Tragante, Vinicius;
    • Rajamani, Sridharan;
    • Helgadottir, Anna;
    • Gretarsdottir, Solveig;
    • van Setten, Jessica;
    • Asselbergs, Folkert W.;
    • Sverrisson, Jon Th.;
    • Stephensen, Sigurdur S.;
    • Oskarsson, Gylfi;
    • Sigurdsson, Emil L.;
    • Andersen, Karl;
    • Danielsen, Ragnar;
    • Thorgeirsson, Gudmundur;
    • Thorsteinsdottir, Unnur;
    • Arnar, David O.;
    • Sulem, Patrick
    Publication type:
    Article

  • Transcriptome-wide association study of multiple myeloma identifies candidate susceptibility genes.

    Published in:
    Human Genomics, 2019, v. 13, n. 1, p. N.PAG, doi. 10.1186/s40246-019-0231-5
    By:
    • Went, Molly;
    • Kinnersley, Ben;
    • Sud, Amit;
    • Johnson, David C.;
    • Weinhold, Niels;
    • Försti, Asta;
    • van Duin, Mark;
    • Orlando, Giulia;
    • Mitchell, Jonathan S.;
    • Kuiper, Rowan;
    • Walker, Brian A.;
    • Gregory, Walter M.;
    • Hoffmann, Per;
    • Jackson, Graham H.;
    • Nöthen, Markus M.;
    • da Silva Filho, Miguel Inacio;
    • Thomsen, Hauke;
    • Broyl, Annemiek;
    • Davies, Faith E.;
    • Thorsteinsdottir, Unnur
    Publication type:
    Article

  • Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-09304-9
    By:
    • Ivarsdottir, Erna V.;
    • Benonisdottir, Stefania;
    • Thorleifsson, Gudmar;
    • Sulem, Patrick;
    • Oddsson, Asmundur;
    • Styrkarsdottir, Unnur;
    • Kristmundsdottir, Snaedis;
    • Arnadottir, Gudny A.;
    • Thorgeirsson, Gudmundur;
    • Jonsdottir, Ingileif;
    • Zoega, Gunnar M.;
    • Thorsteinsdottir, Unnur;
    • Gudbjartsson, Daniel F.;
    • Jonasson, Fridbert;
    • Holm, Hilma;
    • Stefansson, Kari
    Publication type:
    Article

  • Compound heterozygous mutations in UBA5 causing early-onset epileptic encephalopathy in two sisters.

    Published in:
    2017
    By:
    • Arnadottir, Gudny A.;
    • Jensson, Brynjar O.;
    • Marelsson, Sigurdur E.;
    • Sulem, Gerald;
    • Oddsson, Asmundur;
    • Kristjansson, Ragnar P.;
    • Benonisdottir, Stefania;
    • Gudjonsson, Sigurjon A.;
    • Masson, Gisli;
    • Thorisson, Gudmundur A.;
    • Saemundsdottir, Jona;
    • Magnusson, Olafur Th.;
    • Jonasdottir, Adalbjorg;
    • Jonasdottir, Aslaug;
    • Sigurdsson, Asgeir;
    • Gudbjartsson, Daniel F.;
    • Thorsteinsdottir, Unnur;
    • Arngrimsson, Reynir;
    • Sulem, Patrick;
    • Stefansson, Kari
    Publication type:
    Case Study

  • Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locus.

    Published in:
    Human Molecular Genetics, 2017, v. 26, n. 19, p. 3850, doi. 10.1093/hmg/ddx285
    By:
    • Hackinger, Sophie;
    • Trajanoska, Katerina;
    • Styrkarsdottir, Unnur;
    • Zengini, Eleni;
    • Steinberg, Julia;
    • Ritchie, Graham R. S.;
    • Hatzikotoulas, Konstantinos;
    • Gilly, Arthur;
    • Evangelou, Evangelos;
    • Kemp, John P.;
    • Evans, David;
    • Ingvarsson, Thorvaldur;
    • Jonsson, Helgi;
    • Thorsteinsdottir, Unnur;
    • Stefansson, Kari;
    • McCaskie, Andrew W.;
    • Brooks, Roger A.;
    • Wilkinson, Jeremy M.;
    • Rivadeneira, Fernando;
    • Zeggini, Eleftheria
    Publication type:
    Article

  • Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis.

    Published in:
    Nature Communications, 2017, v. 8, n. 6, p. 15789, doi. 10.1038/ncomms15789
    By:
    • Sigurdsson, Snaevar;
    • Alexandersson, Kristjan F.;
    • Sulem, Patrick;
    • Feenstra, Bjarke;
    • Gudmundsdottir, Steinunn;
    • Halldorsson, Gisli H.;
    • Olafsson, Sigurgeir;
    • Sigurdsson, Asgeir;
    • Rafnar, Thorunn;
    • Thorgeirsson, Thorgeir;
    • Sørensen, Erik;
    • Nordholm-Carstensen, Andreas;
    • Burcharth, Jakob;
    • Andersen, Jens;
    • Jørgensen, Henrik Stig;
    • Possfelt-Møller, Emma;
    • Ullum, Henrik;
    • Thorleifsson, Gudmar;
    • Masson, Gisli;
    • Thorsteinsdottir, Unnur
    Publication type:
    Article

  • Multi-nucleotide de novo Mutations in Humans.

    Published in:
    PLoS Genetics, 2016, v. 12, n. 11, p. 1, doi. 10.1371/journal.pgen.1006315
    By:
    • Besenbacher, Søren;
    • Sulem, Patrick;
    • Helgason, Agnar;
    • Helgason, Hannes;
    • Kristjansson, Helgi;
    • Jonasdottir, Aslaug;
    • Jonasdottir, Adalbjorg;
    • Magnusson, Olafur Th.;
    • Thorsteinsdottir, Unnur;
    • Masson, Gisli;
    • Kong, Augustine;
    • Gudbjartsson, Daniel F.;
    • Stefansson, Kari
    Publication type:
    Article

  • Erratum: A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.

    Published in:
    Nature Communications, 2016, v. 7, n. 9, p. 12869, doi. 10.1038/ncomms12869
    By:
    • Rivas, Manuel A.;
    • Graham, Daniel;
    • Sulem, Patrick;
    • Stevens, Christine;
    • Desch, A. Nicole;
    • Goyette, Philippe;
    • Gudbjartsson, Daniel;
    • Jonsdottir, Ingileif;
    • Thorsteinsdottir, Unnur;
    • Degenhardt, Frauke;
    • Mucha, Sören;
    • Kurki, Mitja I.;
    • Li, Dalin;
    • D'Amato, Mauro;
    • Annese, Vito;
    • Vermeire, Severine;
    • Weersma, Rinse K.;
    • Halfvarson, Jonas;
    • Paavola-Sakki, Paulina;
    • Lappalainen, Maarit
    Publication type:
    Article

  • A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.

    Published in:
    Nature Communications, 2016, v. 7, n. 8, p. 12342, doi. 10.1038/ncomms12342
    By:
    • Rivas, Manuel A.;
    • Graham, Daniel;
    • Sulem, Patrick;
    • Stevens, Christine;
    • Desch, A. Nicole;
    • Goyette, Philippe;
    • Gudbjartsson, Daniel;
    • Jonsdottir, Ingileif;
    • Thorsteinsdottir, Unnur;
    • Degenhardt, Frauke;
    • Mucha, Sören;
    • Kurki, Mitja I.;
    • Li, Dalin;
    • D'Amato, Mauro;
    • Annese, Vito;
    • Vermeire, Severine;
    • Weersma, Rinse K.;
    • Halfvarson, Jonas;
    • Paavola-Sakki, Paulina;
    • Lappalainen, Maarit
    Publication type:
    Article

  • Common variants upstream of KDR encoding VEGFR2 and in TTC39B associate with endometriosis.

    Published in:
    Nature Communications, 2016, v. 7, n. 7, p. 12350, doi. 10.1038/ncomms12350
    By:
    • Steinthorsdottir, Valgerdur;
    • Thorleifsson, Gudmar;
    • Aradottir, Kristrun;
    • Feenstra, Bjarke;
    • Sigurdsson, Asgeir;
    • Stefansdottir, Lilja;
    • Kristinsdottir, Anna M.;
    • Zink, Florian;
    • Halldorsson, Gisli H.;
    • Munk Nielsen, Nete;
    • Geller, Frank;
    • Melbye, Mads;
    • Gudbjartsson, Daniel F.;
    • Geirsson, Reynir T.;
    • Thorsteinsdottir, Unnur;
    • Stefansson, Kari
    Publication type:
    Article

  • Two Rare Mutations in the COL1A2 Gene Associate With Low Bone Mineral Density and Fractures in Iceland.

    Published in:
    Journal of Bone & Mineral Research, 2016, v. 31, n. 1, p. 173, doi. 10.1002/jbmr.2604
    By:
    • Styrkarsdottir, Unnur;
    • Thorleifsson, Gudmar;
    • Eiriksdottir, Berglind;
    • Gudjonsson, Sigurjon A.;
    • Ingvarsson, Thorvaldur;
    • Center, Jacqueline R.;
    • Nguyen, Tuan V.;
    • Eisman, John A.;
    • Christiansen, Claus;
    • Thorsteinsdottir, Unnur;
    • Sigurdsson, Gunnar;
    • Stefansson, Kari
    Publication type:
    Article

  • Protolichesterinic Acid, Isolated from the Lichen Cetraria islandica, Reduces LRRC8A Expression and Volume-Sensitive Release of Organic Osmolytes in Human Lung Epithelial Cancer Cells.

    Published in:
    2016
    By:
    • Thorsteinsdottir, Unnur Arna;
    • Thorsteinsdottir, Margret;
    • Lambert, Ian Henry
    Publication type:
    journal article

  • Common and rare variants associated with kidney stones and biochemical traits.

    Published in:
    Nature Communications, 2015, v. 6, n. 8, p. 7975, doi. 10.1038/ncomms8975
    By:
    • Oddsson, Asmundur;
    • Sulem, Patrick;
    • Helgason, Hannes;
    • Edvardsson, Vidar O.;
    • Thorleifsson, Gudmar;
    • Sveinbjörnsson, Gardar;
    • Haraldsdottir, Eik;
    • Eyjolfsson, Gudmundur I.;
    • Sigurdardottir, Olof;
    • Olafsson, Isleifur;
    • Masson, Gisli;
    • Holm, Hilma;
    • Gudbjartsson, Daniel F.;
    • Thorsteinsdottir, Unnur;
    • Indridason, Olafur S.;
    • Palsson, Runolfur;
    • Stefansson, Kari
    Publication type:
    Article

  • Association Analysis of 29,956 Individuals Confirms That a Low-Frequency Variant at CCND2 Halves the Risk of Type 2 Diabetes by Enhancing Insulin Secretion.

    Published in:
    Diabetes, 2015, v. 64, n. 6, p. 2279, doi. 10.2337/db14-1456
    By:
    • Yaghootkar, Hanieh;
    • Stancáková, Alena;
    • Freathy, Rachel M.;
    • Vangipurapu, Jagadish;
    • Weedon, Michael N.;
    • Weijia Xie;
    • Wood, Andrew R.;
    • Ferrannini, Ele;
    • Mari, Andrea;
    • Ring, Susan M.;
    • Lawlor, Debbie A.;
    • Smith, George Davey;
    • Jørgensen, Torben;
    • Hansen, Torben;
    • Pedersen, Oluf;
    • Steinthorsdottir, Valgerdur;
    • Guðbjartsson, Daniel F.;
    • Thorleifsson, Gudmar;
    • Thorsteinsdottir, Unnur;
    • Stefansson, Kari
    Publication type:
    Article

  • Identification of a large set of rare complete human knockouts.

    Published in:
    Nature Genetics, 2015, v. 47, n. 5, p. 448, doi. 10.1038/ng.3243
    By:
    • Sulem, Patrick;
    • Oddson, Asmundur;
    • Stefansson, Hreinn;
    • Gudjonsson, Sigurjon A;
    • Zink, Florian;
    • Hjartarson, Eirikur;
    • Sigurdsson, Gunnar Th;
    • Jonasdottir, Adalbjorg;
    • Jonasdottir, Aslaug;
    • Sigurdsson, Asgeir;
    • Magnusson, Olafur Th;
    • Masson, Gisli;
    • Helgason, Hannes;
    • Kong, Augustine;
    • Gudbjartsson, Daniel F;
    • Helgason, Agnar;
    • Holm, Hilma;
    • Thorsteinsdottir, Unnur;
    • Stefansson, Kari
    Publication type:
    Article

  • Rare mutations associating with serum creatinine and chronic kidney disease.

    Published in:
    Human Molecular Genetics, 2014, v. 23, n. 25, p. 6935, doi. 10.1093/hmg/ddu399
    By:
    • Sveinbjornsson, Gardar;
    • Mikaelsdottir, Evgenia;
    • Palsson, Runolfur;
    • Indridason, Olafur S.;
    • Holm, Hilma;
    • Jonasdottir, Aslaug;
    • Helgason, Agnar;
    • Sigurdsson, Snaevar;
    • Jonasdottir, Adalbjorg;
    • Sigurdsson, Asgeir;
    • Eyjolfsson, Gudmundur Ingi;
    • Sigurdardottir, Olof;
    • Magnusson, Olafur Th.;
    • Kong, Augustine;
    • Masson, Gisli;
    • Sulem, Patrick;
    • Olafsson, Isleifur;
    • Thorsteinsdottir, Unnur;
    • Gudbjartsson, Daniel F.;
    • Stefansson, Kari
    Publication type:
    Article

  • Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma.

    Published in:
    Nature Genetics, 2014, v. 46, n. 10, p. 1126, doi. 10.1038/ng.3087
    By:
    • Hysi, Pirro G;
    • Hammond, Christopher J;
    • Höhn, René;
    • Mirshahi, Alireza;
    • Pfeiffer, Norbert;
    • Venturini, Cristina;
    • Ramdas, Wishal D;
    • Vingerling, Johannes R;
    • Klaver, Caroline C W;
    • Thorleifsson, Gudmar;
    • Thorsteinsdottir, Unnur;
    • Stefansson, Kari;
    • Vithana, Eranga;
    • Khor, Chiea-Chuen;
    • Stefansson, Arni B;
    • Liao, Jiemin;
    • Haines, Jonathan L;
    • Amin, Najaf;
    • Karssen, Lennart C;
    • Iglesias, Adriana I
    Publication type:
    Article

  • Common and low-frequency variants associated with genome-wide recombination rate.

    Published in:
    Nature Genetics, 2014, v. 46, n. 1, p. 11, doi. 10.1038/ng.2833
    By:
    • Kong, Augustine;
    • Thorleifsson, Gudmar;
    • Frigge, Michael L;
    • Masson, Gisli;
    • Gudbjartsson, Daniel F;
    • Villemoes, Rasmus;
    • Magnusdottir, Erna;
    • Olafsdottir, Stefania B;
    • Thorsteinsdottir, Unnur;
    • Stefansson, Kari
    Publication type:
    Article

  • Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization.

    Published in:
    Nature Genetics, 2013, v. 45, n. 8, p. 902, doi. 10.1038/ng.2694
    By:
    • Bønnelykke, Klaus;
    • Matheson, Melanie C;
    • Pers, Tune H;
    • Granell, Raquel;
    • Strachan, David P;
    • Alves, Alexessander Couto;
    • Linneberg, Allan;
    • Curtin, John A;
    • Warrington, Nicole M;
    • Standl, Marie;
    • Kerkhof, Marjan;
    • Jonsdottir, Ingileif;
    • Bukvic, Blazenka K;
    • Kaakinen, Marika;
    • Sleimann, Patrick;
    • Thorleifsson, Gudmar;
    • Thorsteinsdottir, Unnur;
    • Schramm, Katharina;
    • Baltic, Svetlana;
    • Kreiner-Møller, Eskil
    Publication type:
    Article

  • Rare Genomic Structural Variants in Complex Disease: Lessons from the Replication of Associations with Obesity.

    Published in:
    PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058048
    By:
    • Walters, Robin G.;
    • Coin, Lachlan J. M.;
    • Ruokonen, Aimo;
    • de Smith, Adam J.;
    • El-Sayed Moustafa, Julia S.;
    • Jacquemont, Sebastien;
    • Elliott, Paul;
    • Esko, Tõnu;
    • Hartikainen, Anna-Liisa;
    • Laitinen, Jaana;
    • Männik, Katrin;
    • Martinet, Danielle;
    • Meyre, David;
    • Nauck, Matthias;
    • Schurmann, Claudia;
    • Sladek, Rob;
    • Thorleifsson, Gudmar;
    • Thorsteinsdóttir, Unnur;
    • Valsesia, Armand;
    • Waeber, Gerard
    Publication type:
    Article

  • Rare mutations associating with serum creatinine and chronic kidney disease.

    Published in:
    Human Molecular Genetics, 2012, v. 21, n. 25, p. 1, doi. 10.1093/hmg/ddu399
    By:
    • Sveinbjornsson, Gardar;
    • Mikaelsdottir, Evgenia;
    • Palsson, Runolfur;
    • Indridason, Olafur S.;
    • Holm, Hilma;
    • Jonasdottir, Aslaug;
    • Helgason, Agnar;
    • Sigurdsson, Snaevar;
    • Jonasdottir, Adalbjorg;
    • Sigurdsson, Asgeir;
    • Eyjolfsson, Gudmundur Ingi;
    • Sigurdardottir, Olof;
    • Magnusson, Olafur Th.;
    • Kong, Augustine;
    • Masson, Gisli;
    • Sulem, Patrick;
    • Olafsson, Isleifur;
    • Thorsteinsdottir, Unnur;
    • Gudbjartsson, Daniel F.;
    • Stefansson, Kari
    Publication type:
    Article

  • Rate of de novo mutations and the importance of father's age to disease risk.

    Published in:
    Nature, 2012, v. 488, n. 7412, p. 471, doi. 10.1038/nature11396
    By:
    • Kong, Augustine;
    • Frigge, Michael L.;
    • Masson, Gisli;
    • Besenbacher, Soren;
    • Sulem, Patrick;
    • Magnusson, Gisli;
    • Gudjonsson, Sigurjon A.;
    • Sigurdsson, Asgeir;
    • Jonasdottir, Aslaug;
    • Jonasdottir, Adalbjorg;
    • Wong, Wendy S. W.;
    • Sigurdsson, Gunnar;
    • Walters, G. Bragi;
    • Steinberg, Stacy;
    • Helgason, Hannes;
    • Thorleifsson, Gudmar;
    • Gudbjartsson, Daniel F.;
    • Helgason, Agnar;
    • Magnusson, Olafur Th.;
    • Thorsteinsdottir, Unnur
    Publication type:
    Article

  • Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans.

    Published in:
    Cardiovascular Research, 2011, v. 90, n. 1, p. 18
    By:
    • Michel, Jean-Baptiste;
    • Martin-Ventura, José-Luis;
    • Egido, Jesus;
    • Sakalihasan, Natzi;
    • Treska, Vladislav;
    • Lindholt, Jes;
    • Allaire, Eric;
    • Thorsteinsdottir, Unnur;
    • Cockerill, Gillian;
    • Swedenborg, Jesper
    Publication type:
    Article

  • Fine-scale recombination rate differences between sexes, populations and individuals.

    Published in:
    Nature, 2010, v. 467, n. 7319, p. 1099, doi. 10.1038/nature09525
    By:
    • Kong, Augustine;
    • Thorleifsson, Gudmar;
    • Gudbjartsson, Daniel F.;
    • Masson, Gisli;
    • Sigurdsson, Asgeir;
    • Jonasdottir, Aslaug;
    • Walters, G. Bragi;
    • Jonasdottir, Adalbjorg;
    • Gylfason, Arnaldur;
    • Kristinsson, Kari Th.;
    • Gudjonsson, Sigurjon A.;
    • Frigge, Michael L.;
    • Helgason, Agnar;
    • Thorsteinsdottir, Unnur;
    • Stefansson, Kari
    Publication type:
    Article

  • Association of Variants at UMOD with Chronic Kidney Disease and Kidney Stones-Role of Age and Comorbid Diseases.

    Published in:
    PLoS Genetics, 2010, v. 6, n. 7, p. 1, doi. 10.1371/journal.pgen.1001039
    By:
    • Gudbjartsson, Daniel F.;
    • Holm, Hilma;
    • Indridason, Olafur S.;
    • Thorleifsson, Gudmar;
    • Edvardsson, Vidar;
    • Sulem, Patrick;
    • de Vegt, Femmie;
    • d'Ancona, Frank C. H.;
    • den Heijer, Martin;
    • Franzson, Leifur;
    • Rafnar, Thorunn;
    • Kristjansson, Kristleifur;
    • Bjornsdottir, Unnur S.;
    • Eyjolfsson, Gudmundur I.;
    • Kiemeney, Lambertus A.;
    • Kong, Augustine;
    • Palsson, Runolfur;
    • Thorsteinsdottir, Unnur;
    • Stefansson, Kari
    Publication type:
    Article

  • Several common variants modulate heart rate, PR interval and QRS duration.

    Published in:
    Nature Genetics, 2010, v. 42, n. 2, p. 117, doi. 10.1038/ng.511
    By:
    • Holm, Hilma;
    • Gudbjartsson, Daniel F.;
    • Arnar, David O.;
    • Thorleifsson, Gudmar;
    • Thorgeirsson, Gudmundur;
    • Stefansdottir, Hrafnhildur;
    • Gudjonsson, Sigurjon A.;
    • Jonasdottir, Aslaug;
    • Mathiesen, Ellisiv B.;
    • Njølstad, Inger;
    • Nyrnes, Audhild;
    • Wilsgaard, Tom;
    • Hald, Erin M.;
    • Hveem, Kristian;
    • Stoltenberg, Camilla;
    • Løchen, Maja-Lisa;
    • Kong, Augustine;
    • Thorsteinsdottir, Unnur;
    • Stefansson, Kari
    Publication type:
    Article

  • New sequence variants associated with bone mineral density.

    Published in:
    Nature Genetics, 2009, v. 41, n. 1, p. 15, doi. 10.1038/ng.284
    By:
    • Styrkarsdottir, Unnur;
    • Halldorsson, Bjarni V.;
    • Gretarsdottir, Solveig;
    • Gudbjartsson, Daniel F.;
    • Walters, G. Bragi;
    • Ingvarsson, Thorvaldur;
    • Jonsdottir, Thorbjorg;
    • Saemundsdottir, Jona;
    • Snorradóttir, Steinunn;
    • Center, Jacqueline R.;
    • Nguyen, Tuan V.;
    • Alexandersen, Peter;
    • Gulcher, Jeffrey R.;
    • Eisman, John A.;
    • Christiansen, Claus;
    • Sigurdsson, Gunnar;
    • Kong, Augustine;
    • Thorsteinsdottir, Unnur;
    • Stefansson, Kari
    Publication type:
    Article

  • Male-pattern baldness susceptibility locus at 20p11.

    Published in:
    Nature Genetics, 2008, v. 40, n. 11, p. 1282, doi. 10.1038/ng.255
    By:
    • Richards, J Brent;
    • Yuan, Xin;
    • Geller, Frank;
    • Waterworth, Dawn;
    • Bataille, Veronique;
    • Glass, Daniel;
    • Song, Kijoung;
    • Waeber, Gerard;
    • Vollenweider, Peter;
    • Aben, Katja K H;
    • Kiemeney, Lambertus A;
    • Walters, Bragi;
    • Soranzo, Nicole;
    • Thorsteinsdottir, Unnur;
    • Kong, Augustine;
    • Rafnar, Thorunn;
    • Deloukas, Panos;
    • Sulem, Patrick;
    • Stefansson, Hreinn;
    • Stefansson, Kari
    Publication type:
    Article

  • A Drastic Reduction in the Life Span of Cystatin C L68Q Carriers Due to Life-Style Changes during the Last Two Centuries.

    Published in:
    PLoS Genetics, 2008, v. 4, n. 6, p. 1, doi. 10.1371/journal.pgen.1000099
    By:
    • Palsdottir, Astridur;
    • Helgason, Agnar;
    • Palsson, Snaebjorn;
    • Bjornsson, Hans Tomas;
    • Bragason, Birkir Thor;
    • Gretarsdottir, Solveig;
    • Thorsteinsdottir, Unnur;
    • Olafsson, Elias;
    • Stefansson, Kari
    Publication type:
    Article

  • Support for involvement of the AHI1 locus in schizophrenia.

    Published in:
    European Journal of Human Genetics, 2007, v. 15, n. 9, p. 988, doi. 10.1038/sj.ejhg.5201848
    By:
    • Ingason, Andres;
    • Sigmundsson, Thordur;
    • Steinberg, Stacy;
    • Sigurdsson, Engilbert;
    • Haraldsson, Magnus;
    • Magnusdottir, Brynja B.;
    • Frigge, Michael L.;
    • Kong, Augustine;
    • Gulcher, Jeffrey;
    • Thorsteinsdottir, Unnur;
    • Stefansson, Kari;
    • Petursson, Hannes;
    • Stefansson, Hreinn
    Publication type:
    Article

  • The Association of a SNP Upstream of INSIG2 with Body Mass Index is Reproduced in Several but Not All Cohorts.

    Published in:
    PLoS Genetics, 2007, v. 3, n. 4, p. e61, doi. 10.1371/journal.pgen.0030061
    By:
    • Lyon, Helen N.;
    • Emilsson, Valur;
    • Hinney, Anke;
    • Heid, Iris M.;
    • Lasky-Su, Jessica;
    • Xiaofeng Zhu;
    • Thorleifsson, Gudmar;
    • Gunnarsdottir, Steinunn;
    • Walters, G. Bragi;
    • Thorsteinsdottir, Unnur;
    • Kong, Augustine;
    • Gulcher, Jeffrey;
    • Thuy Trang Nguyen;
    • Scherag, André;
    • Pfeufer, Arne;
    • Meitinger, Thomas;
    • Brönner, Günter;
    • Rief, Winfried;
    • Soto-Quiros, Manuel E.;
    • Avila, Lydiana
    Publication type:
    Article

  • The BARD1 Cys557Ser variant and breast cancer risk in Iceland.

    Published in:
    2006
    By:
    • Stacey, Simon N.;
    • Sulem, Patrick;
    • Johannsson, Oskar T.;
    • Helgason, Agnar;
    • Gudmundsson, Julius;
    • Kostic, Jelena P.;
    • Kristjansson, Kristleifur;
    • Jonsdottir, Thora;
    • Sigurdsson, Helgi;
    • Hrafnkelsson, Jon;
    • Johannsson, Jakob;
    • Sveinsson, Thorarinn;
    • Myrdal, Gardar;
    • Grimsson, Hlynur Niels;
    • Bergthorsson, Jon T.;
    • Amundadottir, Laufey T.;
    • Gulcher, Jeffrey R.;
    • Thorsteinsdottir, Unnur;
    • Kong, Augustine;
    • Stefansson, Kari
    Publication type:
    journal article

  • A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction.

    Published in:
    Nature Genetics, 2006, v. 38, n. 1, p. 68, doi. 10.1038/ng1692
    By:
    • Helgadottir, Anna;
    • Manolescu, Andrei;
    • Helgason, Agnar;
    • Thorleifsson, Gudmar;
    • Thorsteinsdottir, Unnur;
    • Gudbjartsson, Daniel F;
    • Gretarsdottir, Solveig;
    • Magnusson, Kristinn P;
    • Gudmundsson, Gudmundur;
    • Hicks, Andrew;
    • Jonsson, Thorlakur;
    • Grant, Struan F A;
    • Sainz, Jesus;
    • O'Brien, Stephen J;
    • Sveinbjornsdottir, Sigurlaug;
    • Valdimarsson, Einar M;
    • Matthiasson, Stefan E;
    • Levey, Allan I;
    • Abramson, Jerome L;
    • Reilly, Murdach P
    Publication type:
    Article

  • Familial Risk of Lung Carcinoma in the Icelandic Population.

    Published in:
    JAMA: Journal of the American Medical Association, 2004, v. 292, n. 24, p. 2977, doi. 10.1001/jama.292.24.2977
    By:
    • Jonsson, Steinn;
    • Thorsteinsdottir, Unnur;
    • Gudbjartsson, Daniel F.;
    • Jonsson, Hjortur H.;
    • Kristjansson, Kristleifur;
    • Arnason, Sigurdur;
    • Gudnason, Vilmundur;
    • Isaksson, Helgi J.;
    • Hallgrimsson, Jonas;
    • Gulcher, Jeffrey R.;
    • Amundadottir, Laufey T.;
    • Kong, Augustine;
    • Stefansson, Kari
    Publication type:
    Article

  • Cancer as a Complex Phenotype: Pattern of Cancer Distribution within and beyond the Nuclear Family.

    Published in:
    PLoS Medicine, 2004, v. 1, n. 3, p. 229, doi. 10.1371/journal.pmed.0010065
    By:
    • Amundadottir, Laufey T.;
    • Thorvaldsson, Sverrir;
    • Gudbjartsson, Daniel F.;
    • Sulem, Patrick;
    • Kristjansson, Kristleifur;
    • Arnason, Sigurdur;
    • Gulcher, Jeffrey R.;
    • Bjornsson, Johannes;
    • Kong, Augustine;
    • Thorsteinsdottir, Unnur;
    • Stefansson, Kari
    Publication type:
    Article

  • Interstitial deletions including chromosome 3 common eliminated region 1 (C3CER1) prevail in human solid tumors from 10 different tissues.

    Published in:
    Genes, Chromosomes & Cancer, 2004, v. 41, n. 3, p. 232
    By:
    • Thorgunnur Eyfjord Petursdottir;
    • Unnur Thorsteinsdottir;
    • Jon Gunnlaugur Jonasson;
    • Pall Helgi Moller;
    • Chen Huiping;
    • Johannes Bjornsson;
    • Valgardur Egilsson;
    • Stefan Imreh;
    • Sigurdur Ingvarsson
    Publication type:
    Article

  • The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke.

    Published in:
    Nature Genetics, 2004, v. 36, n. 3, p. 233, doi. 10.1038/ng1311
    By:
    • Helgadottir, Anna;
    • Manolescu, Andrei;
    • Thorleifsson, Gudmar;
    • Gretarsdottir, Solveig;
    • Jonsdottir, Helga;
    • Thorsteinsdottir, Unnur;
    • Samani, Nilesh J.;
    • Gudmundsson, Gudmundur;
    • A. Grant, Struan F.;
    • Thorgeirsson, Gudmundur;
    • Sveinbjornsdottir, Sigurlaug;
    • Valdimarsson, Einar M.;
    • Matthiasson, Stefan E.;
    • Johannsson, Halldor;
    • Gudmundsdottir, Olof;
    • Gurney, Mark E.;
    • Sainz, Jesus;
    • Thorhallsdottir, Margret;
    • Andresdottir, Margret;
    • Frigge, Michael L.
    Publication type:
    Article

  • NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice.

    Published in:
    EMBO Journal, 2001, v. 20, n. 3, p. 350, doi. 10.1093/emboj/20.3.350
    By:
    • Kroon, Evert;
    • Thorsteinsdottir, Unnur;
    • Mayotte, Nadine;
    • Nakamura, Takuro;
    • Sauvageau, Guy
    Publication type:
    Article

  • Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b.

    Published in:
    EMBO Journal, 1998, v. 17, n. 13, p. 3714, doi. 10.1093/emboj/17.13.3714
    By:
    • Kroon, Evert;
    • Krosl, Jana;
    • Thorsteinsdottir, Unnur;
    • Baban, Soheyl;
    • Buchberg, Arthur M.;
    • Sauvageau, Guy
    Publication type:
    Article