Works by Thorner, Michael O.

Results: 85

Statement by the Growth Hormone Research Society on the GH/IGF-I Axis in Extending Health Span.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2009, v. 64A, n. 10, p. 1039, doi. 10.1093/gerona/glp091

By:

Thorner, Michael O.

Publication type:

Article

The diagnosis of severe growth hormone deficiency in elderly patients with hypothalamic–pituitary disease.

Published in:

Clinical Endocrinology, 1998, v. 48, n. 5, p. 569, doi. 10.1046/j.1365-2265.1998.00440.x

By:

Toogood, Andrew A.;
Jones, Jenny;
O'Neill, Paul A.;
Thorner, Michael O.;
Shalet, Stephen M.

Publication type:

Article

Relationship between growth hormone (GH) status, serum leptin and body composition in healthy and GH deficient elderly subjects.

Published in:

Clinical Endocrinology, 1997, v. 47, n. 2, p. 161, doi. 10.1046/j.1365-2265.1997.2291056.x

By:

Gill, Matthew S.;
Toogood, Andrew A.;
O'Neill, Paul A.;
Adams, Judith E.;
Thorner, Michael O.;
Shalet, Stephen M.;
Clayton, Peter E.

Publication type:

Article

Pulsatile growth hormone release in normal women during the menstrual cycle.

Published in:

Clinical Endocrinology, 1992, v. 36, n. 6, p. 591, doi. 10.1111/j.1365-2265.1992.tb02270.x

By:

Faria, Amllton C. S.;
Bekenstein, Lori Waranch;
Booth, Robert A.;
Vaccaro, Veronica A.;
Asplin, Christopher M.;
Veldhuls, Johannes D.;
Thorner, Michael O.;
Evans, William S.

Publication type:

Article

Growth Hormone Response to Growth Hormone Releasing Factor in Alzheimer's Disease.

Published in:

Neuroendocrinology, 1989, v. 50, n. 6, p. 663, doi. 10.1159/000125296

By:

Nemeroff, Charles B.;
Krishnan, Ranga Rama;
Belkin, Beth M.;
Ritchie, James C.;
Clark, Christopher;
Vale, Wylie W.;
Rivier, Jean E.;
Thorner, Michael O.

Publication type:

Article

Gonadotropin-Releasing Hormone-Stimulated Phosphoinositide Hydrolysis in the Anterior Pituitary.

Published in:

Neuroendocrinology, 1988, v. 48, n. 5, p. 544, doi. 10.1159/000125061

By:

Sortino, Maria A.;
Evans, William S.;
Speciale, Carmela;
Thorner, Michael O.;
Scapagnini, Umberto;
MacLeod, Robert M.;
Canonico, Pier L.

Publication type:

Article

Spontaneous Sparsely-Granulated Prolactin-Producing Pituitary Adenomas in Aging Rats.

Published in:

Neuroendocrinology, 1985, v. 41, n. 3, p. 201, doi. 10.1159/000124179

By:

McComb, Donna J.;
Hellmann, Pattie;
Kovacs, Kalman;
Scott, Dorothy;
Evans, William S.;
Burdman, José A.;
Thorner, Michael O.

Publication type:

Article

Beta-Adrenergic Stimulation of Growth Hormone Release from Perifused Rat Anterior Pituitary Cells.

Published in:

Neuroendocrinology, 1983, v. 37, n. 6, p. 473, doi. 10.1159/000123597

By:

Perkins, Susan N.;
Evans, William S.;
Thorner, Michael O.;
Cronin, Michael.J.

Publication type:

Article

Zinc May Have a Physiological Role in Regulating Pituitary Prolactin Secretion.

Published in:

Neuroendocrinology, 1983, v. 37, n. 5, p. 317, doi. 10.1159/000123568

By:

Login, Ivan S.;
Thorner, Michael O.;
MacLeod, Robert M.

Publication type:

Article

Luteinizing Hormone Secretion Is Enhanced by Pertussis Toxin, Cholera Toxin, and Forskolin.

Published in:

Neuroendocrinology, 1983, v. 37, n. 2, p. 161, doi. 10.1159/000123535

By:

Cronin, Michael J;
Evans, William S.;
Hewlett, Erik L.;
Rogol, Alan D.;
Thorner, Michael O.

Publication type:

Article

Unremitting Suppression of the Postovariectomy Rise in Plasma LH by Tumor-Induced Hyperprolactinemia.

Published in:

Neuroendocrinology, 1982, v. 35, n. 5, p. 327, doi. 10.1159/000123402

By:

Login, Ivan S.;
Krieg, Richard J.;
Kaiser, Donald L.;
Thorner, Michael O.;
MacLeod, Robert M.

Publication type:

Article

Calcium Rather Than Cyclic AMP as the Physiological Intracellular Regulator of Prolactin Release.

Published in:

Neuroendocrinology, 1980, v. 31, n. 6, p. 390, doi. 10.1159/000123109

By:

Thorner, Michael O.;
Hackett, John T.;
Murad, Ferid;
MacLeod, Robert M.

Publication type:

Article

Oral ghrelin receptor agonist MK-0677 increases serum insulin-like growth factor 1 in hemodialysis patients: a randomized blinded study.

Published in:

Nephrology Dialysis Transplantation, 2018, v. 33, n. 3, p. 523, doi. 10.1093/ndt/gfw474

By:

Campbell, Garland A.;
Patrie, James T.;
Gaylinn, Bruce D.;
Thorner, Michael O.;
Bolton, Warren K.

Publication type:

Article

Hexarelin Modulates the Expression of Growth Hormone Secretagogue Receptor Type 1a mRNA at Hypothalamic and Pituitary Sites.

Published in:

Neuroendocrinology, 2004, v. 80, n. 1, p. 52, doi. 10.1159/000080793

By:

Bresciani, Elena;
Nass, Ralf;
Torsello, Antonio;
Gaylinn, Bruce;
Avallone, Roberta;
Locatelli, Vittorio;
Thorner, Michael O.;
Müller, Eugenio E.

Publication type:

Article

Recombinant Human Leptin Does Not Alter Gut Hormone Levels after Gastric Bypass but May Attenuate Sweet Cravings.

Published in:

International Journal of Endocrinology, 2014, p. 1, doi. 10.1155/2014/120286

By:

Conroy, Rushika;
Febres, Gerardo;
McMahon, Donald J.;
Thorner, Michael O.;
Gaylinn, Bruce D.;
Conwell, Irene;
Aronne, Louis;
Korner, Judith

Publication type:

Article

LEAP2 changes with body mass and food intake in humans and mice.

Published in:

2019

By:

Mani, Bharath K.;
Puzziferri, Nancy;
Zhenyan He;
Rodriguez, Juan A.;
Osborne-Lawrence, Sherri;
Metzger, Nathan P.;
Chhina, Navpreet;
Gaylinn, Bruce;
Thorner, Michael O.;
Thomas, E. Louise;
Bell, Jimmy D.;
Williams, Kevin W.;
Goldstone, Anthony P.;
Zigman, Jeffrey M.;
He, Zhenyan

Publication type:

journal article

Absence of ghrelin protects against early-onset obesity.

Published in:

Journal of Clinical Investigation, 2005, v. 115, n. 12, p. 3573, doi. 10.1172/JCI26003

By:

Wortley, Katherine E.;
del Rincon, Juan-Pablo;
Murray, Jane D.;
Garcia, Karen;
Iida, Keiji;
Thorner, Michael O.;
Sleeman, Mark W.

Publication type:

Article

Development of a Predictive Enrichment Marker for the Oral GH Secretagogue LUM-201 in Pediatric Growth Hormone Deficiency.

Published in:

Journal of the Endocrine Society, 2021, v. 5, n. 6, p. 1, doi. 10.1210/jendso/bvab030

By:

Bright, George M;
Do, Minh-Ha T;
McKew, John C;
Blum, Werner F;
Thorner, Michael O

Publication type:

Article

Corroboration of Height Velocity Prediction Markers for rhGH With an Oral GH Secretagogue Treatment in Children With GHD.

Published in:

Journal of the Endocrine Society, 2021, v. 5, n. 6, p. 1, doi. 10.1210/jendso/bvab029

By:

Blum, Werner F;
Bright, George M;
Do, Minh-Ha T;
McKew, John C;
Chen, Haiying;
Thorner, Michael O

Publication type:

Article

Dietary macronutrient regulation of acyl and desacyl ghrelin concentrations in children with Prader‐Willi syndrome (PWS).

Published in:

Clinical Endocrinology, 2020, v. 93, n. 5, p. 579, doi. 10.1111/cen.14279

By:

Alsaif, Maha;
Pakseresht, Mohammadreza;
Mackenzie, Michelle L.;
Gaylinn, Bruce;
Thorner, Michael O.;
Freemark, Michael;
Field, Catherine J.;
Prado, Carla M.;
Haqq, Andrea M.

Publication type:

Article

Cranially irradiated adult cancer survivors may have normal spontaneous GH secretion in the presence of discordant peak GH responses to stimulation tests (compensated GH deficiency).

Published in:

Clinical Endocrinology, 2009, v. 70, n. 2, p. 287, doi. 10.1111/j.1365-2265.2008.03359.x

By:

Darzy, Ken H.;
Thorner, Michael O.;
Shalet, Stephen M.

Publication type:

Article

Controversy: radiotherapy for acromegaly.

Published in:

Clinical Endocrinology, 2003, v. 58, n. 2, p. 136, doi. 10.1046/j.1365-2265.2003.01705.x

By:

Thorner, Michael O.

Publication type:

Article

Ghrelin, not just another growth hormone secretagogue.

Published in:

Clinical Endocrinology, 2001, v. 55, n. 5, p. 589, doi. 10.1046/j.1365-2265.2001.01392.x

By:

Toogood, Andy A.;
Thorner, Michael O.

Publication type:

Article

Circulating microRNA as a biomarker of human growth hormone administration to patients.

Published in:

Drug Testing & Analysis, 2014, v. 6, n. 3, p. 234, doi. 10.1002/dta.1469

By:

Kelly, Brian N.;
Haverstick, Doris M.;
Lee, Jae K.;
Thorner, Michael O.;
Vance, Mary Lee;
Xin, Wenjun;
Bruns, David E.

Publication type:

Article

A GH Secretagogue Receptor Agonist (LUM-201) Elicits Greater GH Responses than Standard GH Secretagogues in Subjects of a Pediatric GH Deficiency Trial.

Published in:

Hormone Research in Paediatrics, 2022, v. 95, n. 1, p. 76, doi. 10.1159/000524244

By:

Bright, George M.;
Thorner, Michael O.

Publication type:

Article

Muscle mechano growth factor is preferentially induced by growth hormone in growth hormone-deficient lit/lit mice.

Published in:

Journal of Physiology, 2004, v. 560, n. 2, p. 341, doi. 10.1113/jphysiol.2004.069500

By:

Iida, Keiji;
Itoh, Emina;
Dong-Sun Kim;
Del Rincon, Juan P.;
Coschigano, Karen T.;
Kopchick, John J.;
Thorner, Michael O.

Publication type:

Article

The Discovery of Growth Hormone-Releasing Hormone1: An Update.

Published in:

2008

By:

Thorner, Michael O.

Publication type:

Editorial

The Discovery of Growth Hormone-Releasing Hormone1: An Update.

Published in:

2008

By:

Thorner, Michael O.

Publication type:

Editorial

Cranial Irradiation and Growth Hormone Neurosecretory Dysfunction: A Critical Appraisal.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2007, v. 92, n. 5, p. 1666, doi. 10.1210/jc.2006-2599

By:

Darzy, Ken H.;
Pezzoli, Suzan S.;
Thorner, Michael O.;
Shalet, Stephen M.

Publication type:

Article

The Impact of Short-Term Fasting on the Dynamics of 24-Hour Growth Hormone (GH) Secretion in Patients with Severe Radiation-Induced GH Deficiency.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2006, v. 91, n. 3, p. 987, doi. 10.1210/jc.2005-2145

By:

Darzy, Ken H.;
Murray, Robert D.;
Gleeson, Helena K.;
Pezzoli, Suzan S.;
Thorner, Michael O.;
Shalet, Stephen M.

Publication type:

Article

The Dynamics of Growth Hormone (GH) Secretion in Adult Cancer Survivors with Severe GH Deficiency Acquired after Brain Irradiation in Childhood for Nonpituitary Brain Tumors: Evidence for Preserved Pulsatility and Diurnal Variation with Increased Secretory Disorderliness.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2005, v. 90, n. 5, p. 2794, doi. 10.1210/jc.2004-2002

By:

Darzy, Ken H.;
Pezzoli, Suzan S.;
Thorner, Michael O.;
Shalet, Stephen M.

Publication type:

Article

Growth Hormone (GH) Replacement Therapy in Adult- Onset GH Deficiency: Effects on Body Composition in Men and Women in a Double-Blind, Randomized, Placebo-Controlled Trial.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2004, v. 89, n. 5, p. 2048, doi. 10.1210/jc.2003-030346

By:

HOFFMAN, ANDREW R.;
KUNTZE, JOYCE E.;
BAPTISTA, JOYCE;
BAUM, HOWARD B. A.;
BAUMANN, GERHARD P.;
BILLER, BEVERLY M. K.;
CLARK, RICHARD V.;
COOK, DAVID;
INZUCCHI, SILVIO E.;
KLEINBERG, DAVID;
KLIBANSKI, ANNE;
PHILLIPS, LAWRENCE S.;
RIDGWAY, E. CHESTER;
ROBBINS, RICHARD J.;
SCHLECHTE, JANET;
SHARMA, MEETA;
THORNER, MICHAEL O.;
VANCE, MARY LEE

Publication type:

Article

Optimizing Control of Acromegaly: Integrating a Growth Hormone Receptor Antagonist into the Treatment Algorithm.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2003, v. 88, n. 10, p. 4759, doi. 10.1210/jc.2003-030518

By:

CLEMMONS, DAVID R.;
CHIHARA, KAZUO;
FREDA, PAMELA U.;
HO, KEN K. Y.;
KLIBANSKI, ANNE;
MELMED, SHLOMO;
SHALET, STEPHEN M.;
STRASBURGER, CHRISTIAN J.;
TRAINER, PETER J.;
THORNER, MICHAEL O.

Publication type:

Article

Optimizing control of acromegaly: integrating a growth hormone receptor antagonist into the treatment algorithm.

Published in:

2003

By:

Clemmons, David R;
Chihara, Kazuo;
Freda, Pamela U;
Ho, Ken K Y;
Klibanski, Anne;
Melmed, Shlomo;
Shalet, Stephen M;
Strasburger, Christian J;
Trainer, Peter J;
Thorner, Michael O

Publication type:

journal article

Abdominal Visceral Fat and Fasting Insulin Are Important Predictors of 24-Hour GH Release Independent of Age, Gender, and Other Physiological Factors.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2001, v. 86, n. 8, p. 3845, doi. 10.1210/jcem.86.8.7731

By:

CLASEY, JODY L.;
WELTMAN, ARTHUR;
PATRIE, JIM;
WELTMAN, JUDY Y.;
PEZZOLI, SUZAN;
BOUCHARD, CLAUDE;
THORNER, MICHAEL O.;
HARTMAN, MARK L.

Publication type:

Article

The Relationship between 24-Hour Growth Hormone Secretion and Insulin-Like Growth Factor I in Patients with Successfully Treated Acromegaly: Impact of Surgery or Radiotherapy.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2001, v. 86, n. 1, p. 259, doi. 10.1210/jcem.86.1.7154

By:

PEACEY, STEVEN R.;
TOOGOOD, ANDREW A.;
VELDHUIS, JOHANNES D.;
THORNER, MICHAEL O.;
SHALET, STEPHEN M.

Publication type:

Article

Growth hormone (GH) receptor blockade with a PEG-modified GH (B2036-PEG) lowers serum insulin-like growth factor-I but does not acutely stimulate serum GH.

Published in:

1999

By:

THORNER, MICHAEL O.;
STRASBURGER, CHRISTIAN J.;
ZIDA WU;
STRAUME, MARTIN;
BIDLINGMAIER, MARTIN;
PEZZOLI, SUZAN S.;
ZIB, KENNETH;
SCARLETT, JOHN C.;
BENNETT, WILLIAM F.

Publication type:

journal article

Growth Hormone Secretagogue Receptor Expression in Human Pituitary Tumors*.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1998, v. 83, n. 12, p. 4314, doi. 10.1210/jc.83.12.4314

By:

SKINNER, MONICA M.;
NASS, RALF;
LOPES, BEATRIZ;
LAWS, EDWARD R.;
THORNER, MICHAEL O.

Publication type:

Article

Preservation of Growth Hormone Pulsatility Despite Pituitary Pathology, Surgery, and Irradiation.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1997, v. 82, n. 7, p. 2215, doi. 10.1210/jcem.82.7.4103

By:

Toogood, Andrew A.;
Nass, Ralf M.;
Pezzoli, Suzan S.;
O’Neill, Paul A.;
Thorner, Michael O.;
Shalet, Stephen M.

Publication type:

Article

Effect of Obesity and Feeding on the Growth Hormone (GH) Response to the GH Secretagogue L-692,429 in Young Men.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1997, v. 82, n. 4, p. 1154, doi. 10.1210/jcem.82.4.3897

By:

KIRK, SUSAN E.;
GERTZ, BARRY J.;
SCHNEIDER, STEPHEN H.;
HARTMAN, MARK L.;
PEZZOLI, SUZAN S.;
WITTREICH, JOHANNA M.;
KRUPA, DAVID A.;
SEIBOLD, JAMES R.;
THORNER, MICHAEL O.

Publication type:

Article

Management of Prolactinomas.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1997, v. 82, n. 4, p. 996

By:

MOLITCH, MARK E.;
THORNER, MICHAEL O.;
WILSON, CHARLES

Publication type:

Article

Enhancement of Pulsatile Growth Hormone Secretion by Continuous Infusion of a Growth Hormone-Releasing Peptide Mimetic, L-692,429, in Older Adults - A Clinical Research Center Study.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1996, v. 81, n. 8, p. 2874, doi. 10.1210/jc.81.8.2874

By:

CHAPMAN, IAN M.;
HARTMAN, MARK L.;
PEZZOLI, SUZAN S.;
THORNER, MICHAEL O.

Publication type:

Article

Effects of a 7-Day Treatment with a Novel, Orally Active, Growth Hormone (GH) Secretagogue, MK-677, on 24-Hour GH Profiles, Insulin-Like Growth Factor I, and Adrenocortical Function in Normal Young Men.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1996, v. 81, n. 8, p. 2776, doi. 10.1210/jc.81.8.2776

By:

COPINSCHI, GEORGES;
VAN ONDERBERGEN, ANNE;
L’HERMITE-BALfiRIAUX, MIREILLE;
MENDEL, CARL M.;
CAUFRIEZ, ANNE;
LEPROULT, RACHEL;
BOLOGNESE, JAMES A.;
DE SMET, MARINA;
THORNER, MICHAEL O.;
VAN CAUTER, EVE

Publication type:

Article

Pituitary Adenomas Producing Growth Hormone, Prolactin, and One or More Glycoprotein Hormones: A Histologic, Immunohistochemical, and Ultrastructural Study of Four Surgically Removed Tumors.

Published in:

Ultrastructural Pathology, 1983, v. 5, n. 2/3, p. 171, doi. 10.3109/01913128309141837

By:

Horvath, Eva;
Kovacs, Kalman;
Scheithauer, Bernd W.;
Randall, Raymond V.;
Laws, Edward R.;
Thorner, Michael O.;
Tindall, George T.;
Barrow, Daniel L.

Publication type:

Article

Rejuvenation in Older Adults Receiving Oral Ghrelin.

Published in:

2009

By:

Rafael, Hernando;
Gaugg, Markus;
Webster, Jim;
Nass, Ralf M.;
Vance, Mary Lee;
Thorner, Michael O.

Publication type:

Letter

Reversible sellar enlargement due to growth hormone-releasing hormone production by pancreatic endocrine tumors in a acromegalic patient with multiple endocrine neoplasia type I syndrome.

Published in:

1988

By:

Ramsay, Jennifer A.;
Kovacs, Kalman;
Asa, Sylvia L.;
Pike, Malcolm J.;
Thorner, Michael O.;
Ramsay, J A;
Kovacs, K;
Asa, S L;
Pike, M J;
Thorner, M O

Publication type:

journal article

Bromocriptine Inhibits Growth Hormone Release from Rat Pituitary Cells in Primary Culture.

Published in:

Proceedings of the Society for Experimental Biology & Medicine, 1984, v. 175, n. 2, p. 191, doi. 10.3181/00379727-175-41787

By:

Cronin, Michael J.;
Thorner, Michael O.;
Hellmann, Pattie;
Rogol, Alan D.

Publication type:

Article

Reserpine Inhibits Rat Anterior Pituitary Hormone Secretion in Vitro: Effects on GH, TSH, and LH.

Published in:

Proceedings of the Society for Experimental Biology & Medicine, 1982, v. 171, n. 3, p. 247, doi. 10.3181/00379727-171-41506

By:

Login, Ivan S.;
Judd, Allan M.;
Thorner, Michael O.;
MacLeod, Robert M.

Publication type:

Article

A Model System for the Study of Luteinizing Hormone (LH) Secretion: Lack of Effect of Fetal Calf Serum on Gonadotropin-Releasing Hormone Stimulated LH Release1.

Published in:

Proceedings of the Society for Experimental Biology & Medicine, 1982, v. 170, n. 1, p. 82, doi. 10.3181/00379727-170-41402

By:

Borges, Joao L. C.;
Kaiser, Donald L.;
Evans, William S.;
Thorner, Michael O.

Publication type:

Article

A Case for Conservative Management: Characterizing the Natural History of Radiographically Diagnosed Rathke Cleft Cysts.

Published in:

2015

By:

Culver, Silas A;
Grober, Yuval;
Ornan, David A;
Patrie, James T;
Oldfield, Edward H;
Jane, John A Jr;
Thorner, Michael O

Publication type:

journal article