Works by Thomson, John P.

Results: 21

Divergent trajectories to structural diversity impact patient survival in high grade serous ovarian cancer.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60655-y

By:

Ewing, Ailith;
Meynert, Alison;
Silk, Ryan;
Aitken, Stuart;
Bendixsen, Devin P.;
Churchman, Michael;
Brown, Stuart L.;
Hamdan, Alhafidz;
Mattocks, Joanne;
Grimes, Graeme R.;
Ballinger, Tracy;
Hollis, Robert L.;
Simon Herrington, C.;
Thomson, John P.;
Sherwood, Kitty;
Parry, Thomas;
Esiri-Bloom, Edward;
Bartos, Clare;
Croy, Ian;
Ferguson, Michelle

Publication type:

Article

Scottish COVID Cancer Immunity Prevalence Study: A Longitudinal Study of SARS-CoV-2 Immune Response in Patients Receiving Anti–Cancer Treatment.

Published in:

Oncologist, 2023, v. 28, n. 3, p. e145, doi. 10.1093/oncolo/oyac257

By:

Purshouse, Karin;
Thomson, John P;
Vallet, Mahéva;
Alexander, Lorna;
Bonisteel, Isaac;
Brennan, Maree;
Cameron, David A;
Figueroa, Jonine D;
Furrie, Elizabeth;
Haig, Pamela;
Heck, Mattea;
McCaughan, Hugh;
Mitchell, Paul;
McVicars, Heather;
Primrose, Lorraine;
Silva, Ines;
Templeton, Kate;
Wilson, Natalie;
Hall, Peter S

Publication type:

Article

The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals.

Published in:

Archives of Toxicology, 2025, v. 99, n. 5, p. 2197, doi. 10.1007/s00204-025-03982-9

By:

Henderson, C. J.;
McLaren, A. W.;
MacLeod, A. K.;
Lin, D.;
Cameron, A. R.;
Chatham, L. R.;
Moggs, J.;
Inesta-Vaquera, F.;
Thomson, John P.;
Meehan, Richard R.;
Chakravarty, P.;
Schwarz, M.;
Wolf, C. Roland

Publication type:

Article

Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver.

Published in:

Nucleic Acids Research, 2013, v. 41, n. 11, p. 5639, doi. 10.1093/nar/gkt232

By:

Thomson, John P.;
Hunter, Jennifer M.;
Lempiäinen, Harri;
Müller, Arne;
Terranova, Rémi;
Moggs, Jonathan G.;
Meehan, Richard R.

Publication type:

Article

Investigation into the role of the germline epigenome in the transmission of glucocorticoid-programmed effects across generations.

Published in:

Genome Biology, 2018, v. 19, n. 1, p. N.PAG, doi. 10.1186/s13059-018-1422-4

By:

Cartier, Jessy;
Smith, Thomas;
Thomson, John P.;
Rose, Catherine M.;
Khulan, Batbayar;
Heger, Andreas;
Meehan, Richard R.;
Drake, Amanda J.

Publication type:

Article

Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions.

Published in:

Genome Biology, 2017, v. 18, p. 1, doi. 10.1186/s13059-017-1185-3

By:

Cole, John J.;
Robertson, Neil A.;
Rather, Mohammed Iqbal;
Thomson, John P.;
McBryan, Tony;
Sproul, Duncan;
Tina Wang;
Brock, Claire;
Clark, William;
Ideker, Trey;
Meehan, Richard R.;
Miller, Richard A.;
Brown-Borg, Holly M.;
Adams, Peter D.

Publication type:

Article

Distinct histopathological features are associated with molecular subtypes and outcome in low grade serous ovarian carcinoma.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-34627-5

By:

Hollis, Robert L.;
Thomson, John P.;
van Baal, Juliette;
Ilenkovan, Narthana;
Churchman, Michael;
van de Vijver, Koen;
Dijk, Frederike;
Meynert, Alison M.;
Bartos, Clare;
Rye, Tzyvia;
Croy, Ian;
Diana, Patricia;
van Gent, Mignon;
Creedon, Helen;
Nirsimloo, Rachel;
Lok, Christianne;
Gourley, Charlie;
Herrington, C. Simon

Publication type:

Article

Integrated molecular characterisation of endometrioid ovarian carcinoma identifies opportunities for stratification.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00187-y

By:

Hollis, Robert L.;
Stanley, Barbara;
Thomson, John P.;
Churchman, Michael;
Croy, Ian;
Rye, Tzyvia;
Bartos, Clare;
Nussey, Fiona;
Mackean, Melanie;
Meynert, Alison M.;
Semple, Colin A.;
Gourley, Charlie;
Herrington, C. Simon

Publication type:

Article

Phenobarbital Induces Cell Cycle Transcriptional Responses in Mouse Liver Humanized for Constitutive Androstane and Pregnane X Receptors.

Published in:

Toxicological Sciences, 2014, v. 139, n. 2, p. 501, doi. 10.1093/toxsci/kfu038

By:

Luisier, Raphaëlle;
Lempiäinen, Harri;
Scherbichler, Nina;
Braeuning, Albert;
Geissler, Miriam;
Dubost, Valerie;
Müller, Arne;
Scheer, Nico;
Chibout, Salah-Dine;
Hara, Hisanori;
Picard, Frank;
Theil, Diethilde;
Couttet, Philippe;
Vitobello, Antonio;
Grenet, Olivier;
Grasl-Kraupp, Bettina;
Ellinger-Ziegelbauer, Heidrun;
Thomson, John P.;
Meehan, Richard R.;
Elcombe, Clifford R.

Publication type:

Article

Identification of Dlk1-Dio3 Imprinted Gene Cluster Noncoding RNAs as Novel Candidate Biomarkers for Liver Tumor Promotion.

Published in:

Toxicological Sciences, 2013, v. 131, n. 2, p. 375

By:

Lempiäinen, Harri;
Couttet, Philippe;
Bolognani, Federico;
Müller, Arne;
Dubost, Valérie;
Luisier, Raphaëlle;
Del Rio Espinola, Alberto;
Vitry, Veronique;
Unterberger, Elif B.;
Thomson, John P.;
Treindl, Fridolin;
Metzger, Ute;
Wrzodek, Clemens;
Hahne, Florian;
Zollinger, Tulipan;
Brasa, Sarah;
Kalteis, Magdalena;
Marcellin, Magali;
Giudicelli, Fanny;
Braeuning, Albert

Publication type:

Article

Identifying and overcoming a mechanism of resistance to WEE1 kinase inhibitor AZD1775 in high grade serous ovarian cancer cells.

Published in:

European Journal of Gynaecological Oncology, 2022, v. 43, n. 2, p. 183, doi. 10.31083/j.ejgo4302024

By:

Gomez, Miriam K.;
Thomson, John P.;
Grimes, Graeme R.;
Wang, Anderson T.;
Churchman, Michael;
O'Connor, Mark J.;
Gourley, Charlie;
Melton, David W.

Publication type:

Article

Activation of transcription factor circuity in 2i-induced ground state pluripotency is independent of repressive global epigenetic landscapes.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 14, p. 7748, doi. 10.1093/nar/gkaa529

By:

Shukla, Ruchi;
Mjoseng, Heidi K;
Thomson, John P;
Kling, Simon;
Sproul, Duncan;
Dunican, Donncha S;
Ramsahoye, Bernard;
Wongtawan, Tuempong;
Treindl, Fridolin;
Templin, Markus F;
Adams, Ian R;
Pennings, Sari;
Meehan, Richard R

Publication type:

Article

Comparative analysis of affinity-based 5-hydroxymethylation enrichment techniques.

Published in:

Nucleic Acids Research, 2014, v. 42, n. 6, p. 4142, doi. 10.1093/nar/gku089

By:

Thomson, John P.;
Hunter, Jennifer M.;
Nestor, Colm E.;
Dunican, Donncha S.;
Terranova, Rémi;
Moggs, Jonathan G.;
Meehan, Richard R.

Publication type:

Article

Comparative analysis of affinity-based 5-hydroxymethylation enrichment techniques.

Published in:

Nucleic Acids Research, 2013, v. 41, n. 22, p. e206, doi. 10.1093/nar/gkt1080

By:

Thomson, John P.;
Hunter, Jennifer M.;
Nestor, Colm E.;
Dunican, Donncha S.;
Terranova, Rémi;
Moggs, Jonathan G.;
Meehan, Richard R.

Publication type:

Article

Rapid reprogramming of epigenetic and transcriptional profiles in mammalian culture systems.

Published in:

Genome Biology, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s13059-014-0576-y

By:

Nestor, Colm E.;
Ottaviano, Raffaele;
Reinhard, Diana;
Cruickshanks, Hazel A.;
Mjoseng, Heidi K.;
McPherson, Rhoanne C.;
Lentini, Antonio;
Thomson, John P.;
Dunican, Donncha S.;
Pennings, Sari;
Anderton, Stephen M.;
Benson, Mikael;
Meehan, Richard R.

Publication type:

Article

Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway.

Published in:

Genome Biology, 2013, v. 14, n. 5, p. 118, doi. 10.1186/gb-2013-14-5-118

By:

Thomson, John P;
Hunter, Jennifer M;
Meehan, Richard R

Publication type:

Article

Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome.

Published in:

Genome Biology, 2012, v. 13, n. 10, p. 1, doi. 10.1186/gb-2012-13-10-R93

By:

Thomson, John P.;
Lempiäinen, Harri;
Hackett, Jamie A.;
Nestor, Colm E.;
Müller, Arne;
Bolognani, Federico;
Oakeley, Edward J.;
Schübeler, Dirk;
Terranova, Rémi;
Reinhardt, Diana;
Moggs, Jonathan G.;
Meehan, Richard R.

Publication type:

Article

Hypoxia determines survival outcomes of bacterial infection through HIF-1α–dependent reprogramming of leukocyte metabolism.

Published in:

Science Immunology, 2017, v. 2, n. 8, p. 1, doi. 10.1126/sciimmunol.aal2861

By:

Thompson, A. A. Roger;
Dickinson, Rebecca S.;
Murphy, Fiona;
Thomson, John P.;
Marriott, Helen M.;
Tavares, Adriana;
Willson, Joseph;
Williams, Lynne;
Lewis, Amy;
Mirchandani, Ananda;
Dos Santos Coelho, Patricia;
Doherty, Catherine;
Ryan, Eilise;
Watts, Emily;
Morton, Nicholas M.;
Forbes, Shareen;
Stimson, Roland H.;
Hameed, Abdul G.;
Arnold, Nadine;
Preston, Julie A.

Publication type:

Article

Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18819-5

By:

Hollis, Robert L.;
Thomson, John P.;
Stanley, Barbara;
Churchman, Michael;
Meynert, Alison M.;
Rye, Tzyvia;
Bartos, Clare;
Iida, Yasushi;
Croy, Ian;
Mackean, Melanie;
Nussey, Fiona;
Okamoto, Aikou;
Semple, Colin A.;
Gourley, Charlie;
Herrington, C. Simon

Publication type:

Article

CpG islands influence chromatin structure via the CpG-binding protein Cfp1.

Published in:

Nature, 2010, v. 464, n. 7291, p. 1082, doi. 10.1038/nature08924

By:

Thomson, John P.;
Skene, Peter J.;
Selfridge, Jim;
Clouaire, Thomas;
Guy, Jacky;
Webb, Shaun;
Kerr, Alastair R. W.;
Deaton, Aimée;
Andrews, Rob;
James, Keith D.;
Turner, Daniel J.;
Illingworth, Robert;
Bird, Adrian

Publication type:

Article

Non-alcoholic fatty liver disease (NAFLD) is associated with dynamic changes in DNA hydroxymethylation.

Published in:

Epigenetics, 2020, v. 15, n. 1/2, p. 61, doi. 10.1080/15592294.2019.1649527

By:

Lyall, Marcus J.;
Thomson, John P.;
Cartier, Jessy;
Ottaviano, Raffaele;
Kendall, Timothy J.;
Meehan, Richard R.;
Drake, Amanda J.

Publication type:

Article