Works by Thomas, Christopher M.

Results: 48

Tackling antibiotic resistance.

Published in:

Nature Reviews Microbiology, 2011, v. 9, n. 12, p. 894, doi. 10.1038/nrmicro2693

By:

Bush, Karen;
Courvalin, Patrice;
Dantas, Gautam;
Davies, Julian;
Eisenstein, Barry;
Huovinen, Pentti;
Jacoby, George A.;
Kishony, Roy;
Kreiswirth, Barry N.;
Kutter, Elizabeth;
Lerner, Stephen A.;
Levy, Stuart;
Lewis, Kim;
Lomovskaya, Olga;
Miller, Jeffrey H.;
Mobashery, Shahriar;
Piddock, Laura J. V.;
Projan, Steven;
Thomas, Christopher M.;
Tomasz, Alexander

Publication type:

Article

Resistance to and synthesis of the antibiotic mupirocin.

Published in:

Nature Reviews Microbiology, 2010, v. 8, n. 4, p. 281, doi. 10.1038/nrmicro2278

By:

Thomas, Christopher M.;
Hothersall, Joanne;
Willis, Christine L.;
Simpson, Thomas J.

Publication type:

Article

Fine Tuning of Antibiotic Activity by a Tailoring Hydroxylase in a Trans‐AT Polyketide Synthase Pathway.

Published in:

ChemBioChem, 2018, v. 19, n. 8, p. 836, doi. 10.1002/cbic.201800036

By:

Mohammad, Hadi H.;
Connolly, Jack A.;
Song, Zhongshu;
Hothersall, Joanne;
Race, Paul R.;
Willis, Christine L.;
Simpson, Thomas J.;
Winn, Peter J.;
Thomas, Christopher M.

Publication type:

Article

Engineered Thiomarinol Antibiotics Active against MRSA Are Generated by Mutagenesis and Mutasynthesis of Pseudoalteromonas SANK73390.

Published in:

Angewandte Chemie, 2011, v. 123, n. 14, p. 3329, doi. 10.1002/ange.201007029

By:

Murphy, Annabel C.;
Fukuda, Daisuke;
Song, Zhongshu;
Hothersall, Joanne;
Cox, Russell J.;
Willis, Christine L.;
Thomas, Christopher M.;
Simpson, Thomas J.

Publication type:

Article

Manipulation of quorum sensing regulation in Pseudomonas fluorescens NCIMB 10586 to increase mupirocin production.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 90, n. 3, p. 1017, doi. 10.1007/s00253-011-3145-2

By:

Hothersall, Joanne;
Murphy, Annabel C.;
Iqbal, Zafar;
Campbell, Genevieve;
Stephens, Elton R.;
Ji'en Wu;
Cooper, Helen;
Atkinson, Steve;
Williams, Paul;
Crosby, John;
Willis, Christine L.;
Cox, Russell J.;
Simpson, Thomas J.;
Thomas, Christopher M.

Publication type:

Article

Mupirocin: biosynthesis, special features and applications of an antibiotic from a Gram-negative bacterium.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 90, n. 1, p. 11, doi. 10.1007/s00253-011-3128-3

By:

Gurney, Rachel;
Thomas, Christopher M.

Publication type:

Article

Maintenance of broad host range plasmid RK2 replicons in Pseudomonas aeruginosa.

Published in:

Nature, 1982, v. 298, n. 5875, p. 674, doi. 10.1038/298674a0

By:

Thomas, Christopher M.;
Hussain, Atta A. K.;
Smith, Christopher A.

Publication type:

Article

Life Cycles of Allocapnia recta and Leuctra spp. (Plecoptera: Capniidae and Leuctridae) Across a Flow Gradient in a Central Kentucky Karst Headwater Stream.

Published in:

Southeastern Naturalist, 2006, v. 5, n. 2, p. 321, doi. 10.1656/1528-7092(2006)5[321:LCOARA]2.0.CO;2

By:

Grubbs, Scott A.;
Thomas, Christopher M.;
Hutchins, Benjamin T.;
Taylor, Jason M.

Publication type:

Article

High quality genome annotation and expression visualisation of a mupirocin-producing bacterium.

Published in:

PLoS ONE, 2022, v. 17, n. 5, p. 1, doi. 10.1371/journal.pone.0268072

By:

Haines, Anthony S.;
Kendrew, Steve G.;
Crowhurst, Nicola;
Stephens, Elton R.;
Connolly, Jack;
Hothersall, Joanne;
Miller, Claire E.;
Collis, Andrew J.;
Huckle, Benjamin D.;
Thomas, Christopher M.

Publication type:

Article

Mechanisms of, and Barriers to, Horizontal Gene Transfer between Bacteria.

Published in:

Nature Reviews Microbiology, 2005, v. 3, n. 9, p. 711, doi. 10.1038/nrmicro1234

By:

Thomas, Christopher M.;
Nielsen, Kaare M.

Publication type:

Article

Complete sequence of the IncP-9 TOL plasmid pWW0 from Pseudomonas putida.

Published in:

Environmental Microbiology, 2002, v. 4, n. 12, p. 856, doi. 10.1046/j.1462-2920.2002.00305.x

By:

Greated, Alicia;
Lambertsen, Lotte;
Williams, Peter A.;
Thomas, Christopher M.

Publication type:

Article

Ability of IncP-9 plasmid pM3 to replicate in Escherichia coli is dependent on both rep and par functions.

Published in:

Molecular Microbiology, 2005, v. 57, n. 3, p. 819, doi. 10.1111/j.1365-2958.2005.04732.x

By:

Sevastsyanovich, Yanina R.;
Titok, Marina A.;
Krasowiak, Renata;
Bingle, Lewis E. H.;
Thomas, Christopher M.

Publication type:

Article

Co-operative interactions control conjugative transfer of broad host-range plasmid RK2: full effect of minor changes in TrbA operator depends on KorB.

Published in:

Molecular Microbiology, 2003, v. 49, n. 4, p. 1095, doi. 10.1046/j.1365-2958.2003.03620.x

By:

Bingle, Lewis E.H.;
Zatyka, Malgorzata;
Manzoor, Susan E.;
Thomas, Christopher M.

Publication type:

Article

Paradigms of plasmid organization.

Published in:

Molecular Microbiology, 2000, v. 37, n. 3, p. 485, doi. 10.1046/j.1365-2958.2000.02006.x

By:

Thomas, Christopher M.

Publication type:

Article

Effect of growth rate and incC mutation on symmetric plasmid distribution by the IncP-1 partitioning apparatus.

Published in:

Molecular Microbiology, 1999, v. 34, n. 2, p. 205, doi. 10.1046/j.1365-2958.1999.01565.x

By:

Bignell, Colin R;
Haines, Anthony S;
Khare, Dheeraj;
Thomas, Christopher M

Publication type:

Article

Repression at a distance by the global regulator KorB of promiscuous IncP plasmids.

Published in:

Molecular Microbiology, 1999, v. 32, n. 3, p. 519, doi. 10.1046/j.1365-2958.1999.01365.x

By:

Jagura-Burdzy, Grazyna;
Macartney, Donia P;
Zatyka, Malgorzata;
Cunliffe, Lesley;
Cooke, Dunstan;
Huggins, Cerys;
Westblade, Lars;
Khanim, Farhat;
Thomas, Christopher M

Publication type:

Article

Potentiation of curing by a broad-host-range self-transmissible vector for displacing resistance plasmids to tackle AMR.

Published in:

PLoS ONE, 2020, v. 15, n. 1, p. 1, doi. 10.1371/journal.pone.0225202

By:

Lazdins, Alessandro;
Maurya, Anand Prakash;
Miller, Claire E.;
Kamruzzaman, Muhammad;
Liu, Shuting;
Stephens, Elton R.;
Lloyd, Georgina S.;
Haratianfar, Mona;
Chamberlain, Melissa;
Haines, Anthony S.;
Kreft, Jan-Ulrich;
Webber, Mark. A.;
Iredell, Jonathan;
Thomas, Christopher M.

Publication type:

Article

Cystic Fibrosis Reprograms Airway Epithelial IL-33 Release and Licenses IL-33–Dependent Inflammation.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2023, v. 207, n. 11, p. 1486, doi. 10.1164/rccm.202211-2096OC

By:

Cook, Daniel P.;
Thomas, Christopher M.;
Wu, Ashley Y.;
Rusznak, Mark;
Jian Zhang;
Weisong Zhou;
Cephus, Jacqueline-Yvonne;
Gibson-Corley, Katherine N.;
Polosukhin, Vasiliy V.;
Norlander, Allison E.;
Newcomb, Dawn C.;
Stoltz, David A.;
Peebles Jr., R. Stokes

Publication type:

Article

Plasmid interference for curing antibiotic resistance plasmids in vivo.

Published in:

PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0172913

By:

Kamruzzaman, Muhammad;
Shoma, Shereen;
Thomas, Christopher M.;
Partridge, Sally R.;
Iredell, Jonathan R.

Publication type:

Article

Engineered Thiomarinol Antibiotics Active against MRSA Are Generated by Mutagenesis and Mutasynthesis of Pseudoalteromonas SANK73390.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 14, p. 3271, doi. 10.1002/anie.201007029

By:

Murphy, Annabel C.;
Fukuda, Daisuke;
Song, Zhongshu;
Hothersall, Joanne;
Cox, Russell J.;
Willis, Christine L.;
Thomas, Christopher M.;
Simpson, Thomas J.

Publication type:

Article

Type 2 inflammation in cystic fibrosis is a predictor of mortality and targeted with CFTR modulator therapy.

Published in:

Allergy, 2024, v. 79, n. 12, p. 3528, doi. 10.1111/all.16198

By:

Cook, Daniel P.;
Wu, Ashley Y.;
Thomas, Christopher M.;
Hamilton, Robert G.;
Stokes Peebles, Ray;
Kerchberger, Vern Eric

Publication type:

Article

Evolution of a Plasmid Regulatory Circuit Ameliorates Plasmid Fitness Cost.

Published in:

Molecular Biology & Evolution, 2025, v. 42, n. 4, p. 1, doi. 10.1093/molbev/msaf062

By:

Elg, Clinton A;
Mack, Erin;
Rolfsmeier, Michael;
McLean, Thomas C;
Sneddon, David;
Kosterlitz, Olivia;
Soderling, Elizabeth;
Narum, Solana;
Rowley, Paul A;
Sullivan, Jack;
Thomas, Christopher M;
Top, Eva M

Publication type:

Article

Sequence-based analysis of pQBR103; a representative of a unique, transfer-proficient mega plasmid resident in the microbial community of sugar beet.

Published in:

ISME Journal: Multidisciplinary Journal of Microbial Ecology, 2007, v. 1, n. 4, p. 331, doi. 10.1038/ismej.2007.47

By:

Tett, Adrian;
Spiers, Andrew J.;
Crossman, Lisa C.;
Ager, Duane;
Ciric, Lena;
Dow, J. Maxwell;
Fry, John C.;
Harris, David;
Lilley, Andrew;
Oliver, Anna;
Parkhill, Julian;
Quail, Michael A.;
Rainey, Paul B.;
Saunders, Nigel J.;
Seeger, Kathy;
Snyder, Lori A. S.;
Squares, Rob;
Thomas, Christopher M.;
Turner, Sarah L.;
Xue-Xian Zhang

Publication type:

Article

Phosphopantetheinylation and Specificity of Acyl Carrier Proteins in the Mupirocin Biosynthetic Cluster.

Published in:

ChemBioChem, 2010, v. 11, n. 2, p. 248, doi. 10.1002/cbic.200900565

By:

Shields, Jennifer A.;
Rahman, Ayesha S.;
Arthur, Christopher J.;
Crosby, John;
Hothersall, Joanne;
Simpson, Thomas J.;
Thomas, Christopher M.

Publication type:

Article

In vivo Mutational Analysis of the Mupirocin Gene Cluster Reveals Labile Points in the Biosynthetic Pathway: the 'Leaky Hosepipe' Mechanism.

Published in:

ChemBioChem, 2008, v. 9, n. 9, p. 1500, doi. 10.1002/cbic.200800085

By:

Wu, Ji'en;
Hothersall, Joanne;
Mazzetti, Carlo;
O'Connell, Yvonne;
Shields, Jennifer A.;
Rahman, Ayesha S.;
Cox, Russell J.;
Crosby, John;
Simpson, Thomas J.;
Thomas, Christopher M.;
Willis, Christine L.

Publication type:

Article

PREFACE.

Published in:

Harvard Journal of Law & Public Policy, 2009, v. 32, n. 3, p. 814

By:

Thomas, Christopher M.

Publication type:

Article

PREFACE.

Published in:

Harvard Journal of Law & Public Policy, 2009, v. 32, n. 2, p. 452

By:

Thomas, Christopher M.

Publication type:

Article

PREFACE.

Published in:

Harvard Journal of Law & Public Policy, 2009, v. 32, n. 1, p. 6

By:

Thomas, Christopher M.

Publication type:

Article

Defining the genes for the final steps in biosynthesis of the complex polyketide antibiotic mupirocin by Pseudomonas fluorescens NCIMB10586.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-38038-9

By:

Connolly, Jack A.;
Wilson, Amber;
Macioszek, Malgorzata;
Song, Zhongshu;
Wang, Luoyi;
Mohammad, Hadi H.;
Yadav, Mukul;
di Martino, Maura;
Miller, Claire E.;
Hothersall, Joanne;
Haines, Anthony S.;
Stephens, Elton R.;
Crump, Matthew P.;
Willis, Christine L.;
Simpson, Thomas J.;
Winn, Peter J.;
Thomas, Christopher M.

Publication type:

Article

A single aromatic residue in transcriptional repressor protein KorA is critical for cooperativity with its co-regulator KorB.

Published in:

Molecular Microbiology, 2008, v. 70, n. 6, p. 1502, doi. 10.1111/j.1365-2958.2008.06498.x

By:

Bingle, Lewis E. H.;
Rajasekar, Karthik V.;
Muntaha, Sidra tul;
Nadella, Vinod;
Hyde, Eva I.;
Thomas, Christopher M.

Publication type:

Article

Stigma in the Sunshine State: How the Eleventh Circuit Ignored Important Equal Protection Considerations and Contributed to the Panic Against the Transgender Community.

Published in:

North Carolina Law Review, 2024, v. 102, n. 2, p. 661

By:

THOMAS, CHRISTOPHER M.

Publication type:

Article

Rücktitelbild: Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics (Angew. Chem. 14/2017).

Published in:

Angewandte Chemie, 2017, v. 129, n. 14, p. 4126, doi. 10.1002/ange.201702123

By:

Gao, Shu ‐ Shan;
Wang, Luoyi;
Song, Zhongshu;
Hothersall, Joanne;
Stevens, Elton R.;
Connolly, Jack;
Winn, Peter J.;
Cox, Russell J.;
Crump, Matthew P.;
Race, Paul R.;
Thomas, Christopher M.;
Simpson, Thomas J.;
Willis, Christine L.

Publication type:

Article

Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics.

Published in:

Angewandte Chemie, 2017, v. 129, n. 14, p. 3988, doi. 10.1002/ange.201611590

By:

Gao, Shu ‐ Shan;
Wang, Luoyi;
Song, Zhongshu;
Hothersall, Joanne;
Stevens, Elton R.;
Connolly, Jack;
Winn, Peter J.;
Cox, Russell J.;
Crump, Matthew P.;
Race, Paul R.;
Thomas, Christopher M.;
Simpson, Thomas J.;
Willis, Christine L.

Publication type:

Article

Activation, incompatibility, and displacement of FIB replicons in E. coliOpen Access.

Published in:

Nucleic Acids Research, 2025, v. 53, n. 7, p. 1, doi. 10.1093/nar/gkaf275

By:

Lloyd, Georgina S;
Stephens, Elton R;
Di Maio, Alessandro;
Thomas, Christopher M

Publication type:

Article

Flexibility of KorA, a plasmid-encoded, global transcription regulator, in the presence and the absence of its operator.

Published in:

Nucleic Acids Research, 2016, v. 44, n. 10, p. 4947, doi. 10.1093/nar/gkw191

By:

Rajasekar, Karthik V.;
Lovering, Andrew L.;
Dancea, Felician;
Scott, David J.;
Harris, Sarah A.;
Bingle, Lewis E. H.;
Roessle, Manfred;
Thomas, Christopher M.;
Hyde, Eva I.;
White, Scott A.

Publication type:

Article

Intrinsic disorder in the partitioning protein KorB persists after co-operative complex formation with operator DNA and KorA.

Published in:

Biochemical Journal, 2017, v. 474, n. 18, p. 3121, doi. 10.1042/BCJ20170281

By:

Hyde, Eva I.;
Callow, Philip;
Rajasekar, Karthik V.;
Timmins, Peter;
Patel, Trushar R.;
Siligardi, Giuliano;
Hussain, Rohanah;
White, Scott A.;
Thomas, Christopher M.;
Scott, David J.

Publication type:

Article

The Biology of Plasmids (Book).

Published in:

1996

By:

Thomas, Christopher M.

Publication type:

Book Review

Conjugative transfer functions of broad-host-range plasmid RK2 are coregulated with vegetative replication.

Published in:

Molecular Microbiology, 1992, v. 6, n. 7, p. 907, doi. 10.1111/j.1365-2958.1992.tb01541.x

By:

Motallebi-Vesharceh, Mostafa;
Balzer, Dietmar;
Lanka, Erich;
Jagura-Burdzy, Grazyna;
Thomas, Christopher M.

Publication type:

Article

Adaptation for Protein Synthesis Efficiency in a Naturally Occurring Self-Regulating Operon.

Published in:

PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0049678

By:

Herman, Dorota;
Thomas, Christopher M.;
Stekel, Dov J.

Publication type:

Article

A Natural Plasmid Uniquely Encodes Two Biosynthetic Pathways Creating a Potent Anti-MRSA Antibiotic.

Published in:

PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0018031

By:

Fukuda, Daisuke;
Haines, Anthony S.;
Song, Zhongshu;
Murphy, Annabel C.;
Hothersall, Joanne;
Stephens, Elton R.;
Gurney, Rachel;
Cox, Russell J.;
Crosby, John;
Willis, Christine L.;
Simpson, Thomas J.;
Thomas, Christopher M.

Publication type:

Article

Complete Genome Sequence and Comparative Metabolic Profiling of the Prototypical Enteroaggregative Escherichia coli Strain 042.

Published in:

PLoS ONE, 2010, v. 5, n. 1, p. 1, doi. 10.1371/journal.pone.0008801

By:

Chaudhuri, Roy R.;
Sebaihia, Mohammed;
Hobman, Jon L.;
Webber, Mark A.;
Leyton, Denisse L.;
Goldberg, Martin D.;
Cunningham, Adam F.;
Scott-Tucker, Anthony;
Ferguson, Paul R.;
Thomas, Christopher M.;
Frankel, Gad;
Tang, Christoph M.;
Dudley, Edward G.;
Roberts, Ian S.;
Rasko, David A.;
Pallen, Mark J.;
Parkhill, Julian;
Nataro, James P.;
Thomson, Nicholas R.;
Henderson, Ian R.

Publication type:

Article

Back Cover: Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics (Angew. Chem. Int. Ed. 14/2017).

Published in:

Angewandte Chemie International Edition, 2017, v. 56, n. 14, p. 4066, doi. 10.1002/anie.201702123

By:

Gao, Shu-Shan;
Wang, Luoyi;
Song, Zhongshu;
Crump, Matthew P.;
Simpson, Thomas J.;
Willis, Christine L.;
Cox, Russell J.;
Hothersall, Joanne;
Stevens, Elton R.;
Connolly, Jack;
Winn, Peter J.;
Thomas, Christopher M.;
Race, Paul R.

Publication type:

Article

Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics.

Published in:

Angewandte Chemie International Edition, 2017, v. 56, n. 14, p. 3930, doi. 10.1002/anie.201611590

By:

Gao, Shu-Shan;
Wang, Luoyi;
Song, Zhongshu;
Crump, Matthew P.;
Simpson, Thomas J.;
Willis, Christine L.;
Cox, Russell J.;
Hothersall, Joanne;
Stevens, Elton R.;
Connolly, Jack;
Winn, Peter J.;
Thomas, Christopher M.;
Race, Paul R.

Publication type:

Article

Guidance on the use of PET for treatment planning in radiotherapy clinical trials.

Published in:

British Journal of Radiology, 2019, v. 92, n. 1103, p. 1, doi. 10.1259/bjr.20190180

By:

Pike, Lucy C;
Thomas, Christopher M;
Guerrero-Urbano, Teresa;
Michaelidou, Andriana;
Greener, Tony;
Miles, Elizabeth;
Eaton, David;
Barrington, Sally F

Publication type:

Article

A conserved motif flags acyl carrier proteins for β-branching in polyketide synthesis.

Published in:

Nature Chemical Biology, 2013, v. 9, n. 11, p. 685, doi. 10.1038/nchembio.1342

By:

Haines, Anthony S;
Dong, Xu;
Song, Zhongshu;
Farmer, Rohit;
Williams, Christopher;
Hothersall, Joanne;
Płoskoń, Eliza;
Wattana-amorn, Pakorn;
Stephens, Elton R;
Yamada, Erika;
Gurney, Rachel;
Takebayashi, Yuiko;
Masschelein, Joleen;
Cox, Russell J;
Lavigne, Rob;
Willis, Christine L;
Simpson, Thomas J;
Crosby, John;
Winn, Peter J;
Thomas, Christopher M

Publication type:

Article

Development and function of regulatory innate lymphoid cells.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1014774

By:

Thomas, Christopher M.;
Peebles Jr., R. Stokes

Publication type:

Article

Inverse Modeling of Global and Regional Energy and Water Cycle Fluxes using Earth Observation Data.

Published in:

Journal of Climate, 2020, v. 33, n. 5, p. 1707, doi. 10.1175/JCLI-D-19-0343.1

By:

Thomas, Christopher M.;
Dong, Bo;
Haines, Keith

Publication type:

Article

The cascading effects of elephant presence/absence on arthropods and an Afrotropical thrush in Arabuko-Sokoke Forest, Kenya John E. Banks et al. Ecological cascades in Arabuko-Sokoke Forest, Kenya.

Published in:

African Journal of Ecology, 2010, v. 48, n. 4, p. 1030, doi. 10.1111/j.1365-2028.2010.01211.x

By:

Banks, John E.;
Jackson, Colin;
Hannon, Lisa M.;
Thomas, Christopher M.;
Baya, Albert;
Njoroge, Laban

Publication type:

Article