Works by Thippeswamy, Thimmasettappa

Results: 36

Mitigating organophosphate nerve agent, soman (GD), induced long-term neurotoxicity: Saracatinib, a Src Tyrosine Kinase inhibitor, as a potential countermeasure.

Published in:

Journal of Neuroinflammation, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12974-025-03520-5

By:

Massey, Nyzil;
Vasanthi, Suraj S.;
Holtkamp, Claire;
Meyer, Christina;
Rao, Nikhil S.;
Gimenez-Lirola, Luis G.;
Wang, Chong;
Im, Hyunmook;
Bevoor, Avinash S.;
Kannurpatti, Sridhar;
Thippeswamy, Thimmasettappa

Publication type:

Article

Gut dysbiosis following organophosphate, diisopropylfluorophosphate (DFP), intoxication and saracatinib oral administration.

Published in:

Frontiers in Microbiomes, 2022, p. 1, doi. 10.3389/frmbi.2022.1006078

By:

Gage, Meghan;
Vinithakumari, Akhil A.;
Mooyottu, Shankumar;
Thippeswamy, Thimmasettappa

Publication type:

Article

Enhanced Fyn-tau and NR2B-PSD95 interactions in epileptic foci in experimental models and human epilepsy.

Published in:

Brain Communications, 2024, v. 6, n. 5, p. 1, doi. 10.1093/braincomms/fcae327

By:

Putra, Marson;
Rao, Nikhil S;
Gardner, Cara;
Liu, Guanghao;
Trommater, Jordan;
Bunney, Michael;
Gage, Meghan;
Bassuk, Alexander G;
Hefti, Marco;
Lee, Gloria;
Thippeswamy, Thimmasettappa

Publication type:

Article

1400W, a selective inducible nitric oxide synthase inhibitor, mitigates early neuroinflammation and nitrooxidative stress in diisopropylfluorophosphate-induced short-term neurotoxicity rat model.

Published in:

Frontiers in Molecular Neuroscience, 2023, v. 16, p. 1, doi. 10.3389/fnmol.2023.1125934

By:

Massey, Nyzil;
Vasanthi, Suraj Sundara;
Samidurai, Manikandan;
Gage, Meghan;
Rao, Nikhil;
Meyer, Christina;
Thippeswamy, Thimmasettappa

Publication type:

Article

Disease-modifying effects of a glial-targeted inducible nitric oxide synthase inhibitor (1400W) in mixed-sex cohorts of a rat soman (GD) model of epilepsy.

Published in:

Journal of Neuroinflammation, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12974-023-02847-1

By:

Vasanthi, Suraj S.;
Rao, Nikhil S.;
Samidurai, Manikandan;
Massey, Nyzil;
Meyer, Christina;
Gage, Meghan;
Kharate, Mihir;
Almanza, Aida;
Wachter, Logan;
Mafuta, Candide;
Trevino, Lily;
Carlo, Adriana M.;
Bryant, Elijah;
Corson, Brooke E.;
Wohlgemuth, Morgan;
Ostrander, Morgan;
Showman, Lucas;
Wang, Chong;
Thippeswamy, Thimmasettappa

Publication type:

Article

The Impacts of Surgery and Intracerebral Electrodes in C57BL/6J Mouse Kainate Model of Epileptogenesis: Seizure Threshold, Proteomics, and Cytokine Profiles.

Published in:

Frontiers in Neurology, 2021, v. 12, p. 1, doi. 10.3389/fneur.2021.625017

By:

Tse, Karen;
Beamer, Edward;
Simpson, Deborah;
Beynon, Robert J.;
Sills, Graeme J.;
Thippeswamy, Thimmasettappa

Publication type:

Article

The Roles of Nitric Oxide in Dorsal Root Ganglion Neurons.

Published in:

Annals of the New York Academy of Sciences, 2002, v. 962, n. 1, p. 103, doi. 10.1111/j.1749-6632.2002.tb04060.x

By:

THIPPESWAMY, THIMMASETTAPPA;
MORRIS, RICHARD

Publication type:

Article

Lithium Chloride Regulation of the Substance P Encoding Preprotachykinin A, Tac1 Gene in Rat Hippocampal Primary Cells.

Published in:

Journal of Molecular Neuroscience, 2011, v. 45, n. 2, p. 94, doi. 10.1007/s12031-010-9431-0

By:

Haddley, Kate;
Spencer, Eleanor;
Vasiliou, Sylvia;
Howard, Mark;
Thippeswamy, Thimmasettappa;
Bubb, Vivien;
Quinn, John

Publication type:

Article

Differential Regulation of Vasoactive Intestinal Peptide (VIP) in the Dentate Gyrus and Hippocampus via the NO-cGMP Pathway Following Kainic Acid-Induced Seizure in the Rat.

Published in:

Journal of Molecular Neuroscience, 2010, v. 42, n. 3, p. 359, doi. 10.1007/s12031-010-9353-x

By:

Cosgrave, Anna;
McKay, Jennifer;
Thippeswamy, Thimmasettappa

Publication type:

Article

Nitric Oxide Regulates Activity-Dependent Neuroprotective Protein (ADNP) in the Dentate Gyrus of the Rodent Model of Kainic Acid-Induced Seizure.

Published in:

Journal of Molecular Neuroscience, 2009, v. 39, n. 1/2, p. 9, doi. 10.1007/s12031-008-9169-0

By:

Cosgrave, Anna;
McKay, Jennifer;
Morris, Richard;
Quinn, John;
Thippeswamy, Thimmasettappa

Publication type:

Article

Nitric Oxide-NGF Mediated PPTA/SP, ADNP, and VIP Expression in the Peripheral Nervous System.

Published in:

Journal of Molecular Neuroscience, 2007, v. 33, n. 3, p. 268, doi. 10.1007/s12031-007-0066-8

By:

Thippeswamy, Thimmasettappa;
Howard, Mark;
Cosgrave, Anna;
Arora, Daleep;
McKay, Jennifer;
Quinn, John

Publication type:

Article

Evidence of Postnatal Neurogenesis in Dorsal Root Ganglion: Role of Nitric Oxide and Neuronal Restrictive Silencer Transcription Factor.

Published in:

Journal of Molecular Neuroscience, 2007, v. 32, n. 2, p. 97, doi. 10.1007/s12031-007-0014-7

By:

Arora, Daleep;
Cosgrave, Anna;
Howard, Mark;
Bubb, Vivien;
Quinn, John;
Thippeswamy, Thimmasettappa

Publication type:

Article

Seizure-Induced Oxidative Stress in Temporal Lobe Epilepsy.

Published in:

BioMed Research International, 2015, v. 2015, p. 1, doi. 10.1155/2015/745613

By:

Puttachary, Sreekanth;
Sharma, Shaunik;
Stark, Sara;
Thippeswamy, Thimmasettappa

Publication type:

Article

Status Epilepticus: Behavioral and Electroencephalography Seizure Correlates in Kainate Experimental Models.

Published in:

Frontiers in Neurology, 2018, p. 1, doi. 10.3389/fneur.2018.00007

By:

Sharma, Shaunik;
Puttachary, Sreekanth;
Thippeswamy, Achala;
Kanthasamy, Anumantha G.;
Thippeswamy, Thimmasettappa

Publication type:

Article

In Focus: Disease promoters during epileptogenesis.

Published in:

Journal of Neuroscience Research, 2019, v. 97, n. 11, p. 1333, doi. 10.1002/jnr.24518

By:

Thippeswamy, Thimmasettappa

Publication type:

Article

The impact of postsynaptic density 95 blocking peptide (Tat‐NR2B9c) and an iNOS inhibitor (1400W) on proteomic profile of the hippocampus in C57BL/6J mouse model of kainate‐induced epileptogenesis.

Published in:

Journal of Neuroscience Research, 2019, v. 97, n. 11, p. 1378, doi. 10.1002/jnr.24441

By:

Tse, Karen;
Hammond, Dean;
Simpson, Deborah;
Beynon, Robert J.;
Beamer, Edward;
Tymianski, Michael;
Salter, Michael W.;
Sills, Graeme J.;
Thippeswamy, Thimmasettappa

Publication type:

Article

Glial source of nitric oxide in epileptogenesis: A target for disease modification in epilepsy.

Published in:

Journal of Neuroscience Research, 2019, v. 97, n. 11, p. 1363, doi. 10.1002/jnr.24205

By:

Sharma, Shaunik;
Puttachary, Sreekanth;
Thippeswamy, Thimmasettappa

Publication type:

Article

The effects of Src tyrosine kinase inhibitor, saracatinib, on the markers of epileptogenesis in a mixed-sex cohort of adult rats in the kainic acid model of epilepsy.

Published in:

Frontiers in Molecular Neuroscience, 2023, p. 01, doi. 10.3389/fnmol.2023.1294514

By:

Rao, Nikhil S.;
Putra, Marson;
Meyer, Christina;
Almanza, Aida;
Thippeswamy, Thimmasettappa

Publication type:

Article

Glial‐mediated neuroprotection: Evidence for the protective role of the NO‐cGMP pathway via neuron–glial communication in the peripheral nervous system.

Published in:

Glia (0894-1491), 2005, v. 49, n. 2, p. 197

By:

Thimmasettappa Thippeswamy;
Jennifer S. Mckay;
Richard Morris;
John Quinn;
Liang‐Fong Wong;
David Murphy

Publication type:

Article

N <sup>w</sup>-Propyl- l-arginine (L-NPA) reduces status epilepticus and early epileptogenic events in a mouse model of epilepsy: behavioural, EEG and immunohistochemical analyses.

Published in:

European Journal of Neuroscience, 2012, v. 36, n. 9, p. 3194, doi. 10.1111/j.1460-9568.2012.08234.x

By:

Beamer, Edward;
Otahal, Jakub;
Sills, Graeme J.;
Thippeswamy, Thimmasettappa

Publication type:

Article

The NADPH Oxidase Inhibitor, Mitoapocynin, Mitigates DFP-Induced Reactive Astrogliosis in a Rat Model of Organophosphate Neurotoxicity.

Published in:

Antioxidants, 2023, v. 12, n. 12, p. 2061, doi. 10.3390/antiox12122061

By:

Meyer, Christina;
Grego, Elizabeth;
S. Vasanthi, Suraj;
Rao, Nikhil S.;
Massey, Nyzil;
Holtkamp, Claire;
Huss, Joselyn;
Showman, Lucas;
Narasimhan, Balaji;
Thippeswamy, Thimmasettappa

Publication type:

Article

Sex‐based structural and functional MRI outcomes in the rat brain after soman (GD) exposure‐induced status epilepticus.

Published in:

Epilepsia Open, 2023, v. 8, n. 2, p. 399, doi. 10.1002/epi4.12701

By:

Gage, Meghan;
Vasanthi, Suraj S;
Meyer, Christina M;
Rao, Nikhil S;
Thedens, Daniel R;
Kannurpatti, Sridhar S.;
Thippeswamy, Thimmasettappa

Publication type:

Article

Fyn-tau Ablation Modifies PTZ-Induced Seizures and Post-seizure Hallmarks of Early Epileptogenesis.

Published in:

Frontiers in Cellular Neuroscience, 2020, v. 14, p. N.PAG, doi. 10.3389/fncel.2020.592374

By:

Putra, Marson;
Puttachary, Sreekanth;
Liu, Guanghao;
Lee, Gloria;
Thippeswamy, Thimmasettappa

Publication type:

Article

Molecular isoforms of high-mobility group box 1 are mechanistic biomarkers for epilepsy.

Published in:

2019

By:

Walker, Lauren Elizabeth;
Frigerio, Federica;
Ravizza, Teresa;
Ricci, Emanuele;
Tse, Karen;
Jenkins, Rosalind E;
Sills, Graeme John;
Jorgensen, Andrea;
Porcu, Luca;
Thippeswamy, Thimmasettappa;
Alapirtti, Tiina;
Peltola, Jukka;
Brodie, Martin J;
Park, Brian Kevin;
Marson, Anthony Guy;
Antoine, Daniel James;
Vezzani, Annamaria;
Pirmohamed, Munir

Publication type:

journal article

Molecular isoforms of high-mobility group box 1 are mechanistic biomarkers for epilepsy.

Published in:

2017

By:

Walker, Lauren Elizabeth;
Frigerio, Federica;
Ravizza, Teresa;
Ricci, Emanuele;
Tse, Karen;
Jenkins, Rosalind E.;
Sills, Graeme John;
Jorgensen, Andrea;
Porcu, Luca;
Thippeswamy, Thimmasettappa;
Alapirtti, Tiina;
Peltola, Jukka;
Brodie, Martin J.;
Park, Brian Kevin;
Marson, Anthony Guy;
Antoine, Daniel James;
Vezzani, Annamaria;
Pirmohamed, Munir

Publication type:

journal article

Sex as a biological variable in the rat model of diisopropylfluorophosphate‐induced long‐term neurotoxicity.

Published in:

Annals of the New York Academy of Sciences, 2020, v. 1479, n. 1, p. 44, doi. 10.1111/nyas.14315

By:

Gage, Meghan;
Golden, Madison;
Putra, Marson;
Sharma, Shaunik;
Thippeswamy, Thimmasettappa

Publication type:

Article

Diapocynin, an NADPH oxidase inhibitor, counteracts diisopropylfluorophosphate‐induced long‐term neurotoxicity in the rat model.

Published in:

Annals of the New York Academy of Sciences, 2020, v. 1479, n. 1, p. 75, doi. 10.1111/nyas.14314

By:

Putra, Marson;
Gage, Meghan;
Sharma, Shaunik;
Gardner, Cara;
Gasser, Grace;
Anantharam, Vellareddy;
Thippeswamy, Thimmasettappa

Publication type:

Article

Inhibitors of Src Family Kinases, Inducible Nitric Oxide Synthase, and NADPH Oxidase as Potential CNS Drug Targets for Neurological Diseases.

Published in:

CNS Drugs, 2021, v. 35, n. 1, p. 1, doi. 10.1007/s40263-020-00787-5

By:

Gage, Meghan C.;
Thippeswamy, Thimmasettappa

Publication type:

Article

Soman (GD) Rat Model to Mimic Civilian Exposure to Nerve Agent: Mortality, Video-EEG Based Status Epilepticus Severity, Sex Differences, Spontaneously Recurring Seizures, and Brain Pathology.

Published in:

Frontiers in Cellular Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fncel.2021.798247

By:

Gage, Meghan;
Rao, Nikhil S.;
Samidurai, Manikandan;
Putra, Marson;
Vasanthi, Suraj S.;
Meyer, Christina;
Wang, Chong;
Thippeswamy, Thimmasettappa

Publication type:

Article

Differential Impact of Severity and Duration of Status Epilepticus , Medical Countermeasures, and a Disease-Modifier, Saracatinib, on Brain Regions in the Rat Diisopropylfluorophosphate Model.

Published in:

Frontiers in Cellular Neuroscience, 2021, v. 15, p. 1, doi. 10.3389/fncel.2021.772868

By:

Gage, Meghan;
Putra, Marson;
Gomez-Estrada, Crystal;
Golden, Madison;
Wachter, Logan;
Gard, Megan;
Thippeswamy, Thimmasettappa

Publication type:

Article

The male sex pheromone darcin stimulates hippocampal neurogenesis and cell proliferation in the subventricular zone in female mice.

Published in:

Frontiers in Behavioral Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fnbeh.2015.00106

By:

Hoffman, Emma;
Pickavance, Lucy;
Thippeswamy, Thimmasettappa;
Beynon, Robert. J.;
Hurst, Jane L.

Publication type:

Article

The Effects of Neuronal Fyn Knockdown in the Hippocampus in the Rat Kainate Model of Temporal Lobe Epilepsy.

Published in:

Cells (2073-4409), 2025, v. 14, n. 10, p. 743, doi. 10.3390/cells14100743

By:

Rao, Nikhil S.;
Putra, Marson;
Meyer, Christina;
Parameswaran, Sirisha;
Thippeswamy, Thimmasettappa

Publication type:

Article

Immediate Epileptogenesis after Kainate-Induced Status Epilepticus in C57BL/6J Mice: Evidence from Long Term Continuous Video-EEG Telemetry.

Published in:

PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0131705

By:

Puttachary, Sreekanth;
Sharma, Shaunik;
Tse, Karen;
Beamer, Edward;
Sexton, Abby;
Crutison, Joseph;
Thippeswamy, Thimmasettappa

Publication type:

Article

Advantages of Repeated Low Dose against Single High Dose of Kainate in C57BL/6J Mouse Model of Status Epilepticus: Behavioral and Electroencephalographic Studies.

Published in:

PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0096622

By:

Tse, Karen;
Puttachary, Sreekanth;
Beamer, Edward;
Sills, Graeme J.;
Thippeswamy, Thimmasettappa

Publication type:

Article

Peripheral and central effects of NADPH oxidase inhibitor, mitoapocynin, in a rat model of diisopropylfluorophosphate (DFP) toxicity.

Published in:

Frontiers in Cellular Neuroscience, 2023, p. 1, doi. 10.3389/fncel.2023.1195843

By:

Meyer, Christina;
Rao, Nikhil S.;
Vasanthi, Suraj S.;
Pereira, Beatriz;
Gage, Meghan;
Putra, Marson;
Holtkamp, Claire;
Huss, Joselyn;
Thippeswamy, Thimmasettappa

Publication type:

Article

NO-cGMP mediated galanin expression in NGF-deprived or axotomized sensory neurons.

Published in:

Journal of Neurochemistry, 2007, v. 100, n. 3, p. 790, doi. 10.1111/j.1471-4159.2006.04243.x

By:

Thippeswamy, Thimmasettappa;
Haddley, Kate;
Corness, Jacquie D.;
Howard, Mark R.;
McKay, Jennifer S.;
Beaucourt, Stephanie M.;
Pope, Marion D.;
Murphy, David;
Morris, Richard;
Hökfelt, Tomas;
Quinn, John P.

Publication type:

Article