Works matching AU Thibault, Olivier

Results: 37

Elevating Insulin Signaling Using a Constitutively Active Insulin Receptor Increases Glucose Metabolism and Expression of GLUT3 in Hippocampal Neurons.

Published in:

Frontiers in Neuroscience, 2020, v. 14, p. 1, doi. 10.3389/fnins.2020.00668

By:

Frazier, Hilaree N.;
Ghoweri, Adam O.;
Anderson, Katie L.;
Lin, Ruei-Lung;
Popa, Gabriel J.;
Mendenhall, Michael D.;
Reagan, Lawrence P.;
Craven, Rolf J.;
Thibault, Olivier

Publication type:

Article

FK506-Binding Protein 12.6/lb, a Negative Regulator of [Ca2+], Rescues Memory and Restores Genomic Regulation in the Hippocampus of Aging Rats.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 4, p. 1030, doi. 10.1523/JNEUROSCI.2234-17.2017

By:

Gant, John C.;
Blalock, Eric M.;
Kuey-Chu Chen;
Thibault, Olivier;
Porter, Nada M.;
Landfield, Philip W.;
Radish, Inga

Publication type:

Article

Reversal of Aging-Related Neuronal Ca2+ Dysregulation and Cognitive Impairment by Delivery of a Transgene Encoding FK506-Binding Protein 12.6/1b to the Hippocampus.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 30, p. 10878, doi. 10.1523/JNEUROSCI.1248-15.2015

By:

Gant, John C.;
Kuey-Chu Chen;
Kadish, Inga;
Blalock, Eric M.;
Thibault, Olivier;
Porter, Nada M.;
Landfield, Philip W.

Publication type:

Article

Deciphering the Relationship Between Astrocyte Calcium Signaling, Neurovascular Coupling, and Cerebrovascular Function in Alzheimer's Disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S8, p. 1, doi. 10.1002/alz.095554

By:

Weiss, Blaine E.;
Gant, John C;
Lin, Ruei‐Lung;
Kraner, Susan D;
Thibault, Olivier;
Sompol, Pradoldej;
Norris, Christopher M.

Publication type:

Article

Astrovascular coupling in the somatosensory cortex of an animal model of amyloidosis at rest and during ambulation.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S8, p. 1, doi. 10.1002/alz.095118

By:

Lin, Ruei‐Lung;
Sims, Sophiya L;
Wright, Nicholas A;
Galopin, Leopoldine B;
Thibault, Olivier

Publication type:

Article

Astrocyte selective insulin receptor knockout in the 5xFAD model of amyloidosis.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S8, p. 1, doi. 10.1002/alz.095027

By:

Wright, Nicholas A;
Galopin, Leopoldine B;
Sims, Sophiya L;
Lin, Ruei‐Lung;
Rucker, Edmund B;
Rogers, Colin B;
Kraner, Susan D;
Norris, Christopher M.;
Thibault, Olivier

Publication type:

Article

Astrocyte calcium dysregulation and cerebrovascular impairments in the 5XFAD mouse model of familial Alzheimer's disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083232

By:

Weiss, Blaine E.;
Gant, John C;
Sompol, Pradoldej;
Thibault, Olivier;
Kraner, Susan D.;
Norris, Christopher M.

Publication type:

Article

Low‐Frequency Oscillations During Resting and Task Differentially Associate with Working Memory Performance in Older Adults.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078984

By:

Venkatesan, Tharunika;
Fei, Ellen;
Hammond, Tyler C;
Zhao, Xiaopeng;
Thibault, Olivier;
Sompol, Pradoldej M;
Norris, Christopher M.;
Jicha, Gregory A;
Jiang, Yang

Publication type:

Article

Falling Short: The Contribution of Central Insulin Receptors to Gait Dysregulation in Brain Aging.

Published in:

Biomedicines, 2022, v. 10, n. 8, p. N.PAG, doi. 10.3390/biomedicines10081923

By:

Case, Sami L.;
Frazier, Hilaree N.;
Anderson, Katie L.;
Lin, Ruei-Lung;
Thibault, Olivier

Publication type:

Article

Hippocampal Expression Analyses Reveal Selective Association of Immediate-Early, Neuroenergetic, and Myelinogenic Pathways with Cognitive Impairment in Aged Rats.

Published in:

Journal of Neuroscience, 2007, v. 27, n. 12, p. 3098, doi. 10.1523/JNEUROSCI.4163-06.2007

By:

Rowe, Wayne B.;
Blalock, Eric M.;
Kuey-Chu Chen;
Kadish, Inga;
Daguang Wang;
Barrett, James E.;
Thibault, Olivier;
Porter, Nada M.;
Rose, Gregory M.;
Landfield, Philip W.

Publication type:

Article

Early and Simultaneous Emergence of Multiple Hippocampal Biomarkers of Aging Is Mediated by Ca2+-Induced Ca2+ Release.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 13, p. 3482, doi. 10.1523/JNEUROSCI.4171-05.2006

By:

Gant, John C.;
Sama, Michelle M.;
Landfield, Philip W.;
Thibault, Olivier

Publication type:

Article

Targeting Astrocyte Signaling Alleviates Cerebrovascular and Synaptic Function Deficits in a Diet-Based Mouse Model of Small Cerebral Vessel Disease.

Published in:

Journal of Neuroscience, 2023, v. 43, n. 10, p. 1797, doi. 10.1523/JNEUROSCI.1333-22.2023

By:

Sompol, Pradoldej;
Gollihue, Jenna L.;
Weiss, Blaine E.;
Ruei-Lung Lin;
Case, Sami L.;
Kraner, Susan D.;
Weekman, Erica M.;
Gant, John C.;
Rogers, Colin B.;
Niedowicz, Dana M.;
Sudduth, Tiffany L.;
Powell, David K.;
Ai-Ling Lin;
Thibault, Olivier;
Wilcock, Donna M.;
Norris, Christopher M.

Publication type:

Article

Disrupting Function of FK506-Binding Protein 1b/12.6 Induces the Ca2+-Dysregulation Aging Phenotype in Hippocampal Neurons.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 5, p. 1693, doi. 10.1523/JNEUROSCI.4805-10.2011

By:

Gant, John C.;
Kuey-Chu Chen;
Norris, Christopher M.;
Kadish, Inga;
Thibault, Olivier;
Blalock, Eric M.;
Porter, Nada M.;
Landfield, Philip W.

Publication type:

Article

Aging-Related Gene Expression in Hippocampus Proper Compared with Dentate Gyrus Is Selectively Associated with Metabolic Syndrome Variables in Rhesus Monkeys.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 17, p. 6058, doi. 10.1523/JNEUROSCI.3956-09.2010

By:

Blalock, Eric M.;
Grondin, Richard;
Kuey-Chu Chen;
Thibault, Olivier;
Thibault, Veronique;
Pandya, Jignesh D.;
Dowling, Amy;
Zhang, Zhiming;
Sullivan, Patrick;
Porter, Nada M.;
Landfield, Philip W.

Publication type:

Article

Hippocampal and Cognitive Aging across the Lifespan: A Bioenergetic Shift Precedes and Increased Cholesterol Trafficking Parallels Memory Impairment.

Published in:

Journal of Neuroscience, 2009, v. 29, n. 6, p. 1805, doi. 10.1523/JNEUROSCI.4599-08.2009

By:

Kadish, Inga;
Thibault, Olivier;
Blalock, Eric M.;
Chen, Kuey-C.;
Gant, John C.;
Porter, Nada M.;
Landfield, Philip W.

Publication type:

Article

Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store.

Published in:

Aging Cell, 2007, v. 6, n. 3, p. 307, doi. 10.1111/j.1474-9726.2007.00295.x

By:

Thibault, Olivier;
Gant, John C.;
Landfield, Philip W.

Publication type:

Article

BRD4 modulates vulnerability of triple-negative breast cancer to targeting of integrin-dependent signaling pathways.

Published in:

Cellular Oncology (2211-3428), 2020, v. 43, n. 6, p. 1049, doi. 10.1007/s13402-020-00537-1

By:

Zhang, Yang;
Xu, Bingwei;
Shi, Junfeng;
Li, Jieming;
Lu, Xinlan;
Xu, Li;
Yang, Helen;
Hamad, Nevean;
Wang, Chi;
Napier, Dana;
He, Shuixiang;
Liu, Chunming;
Liu, Zeyi;
Qian, Hai;
Chen, Li;
Wei, Xiaowei;
Zheng, Xucai;
Huang, Jian-An;
Thibault, Olivier;
Craven, Rolf

Publication type:

Article

Age‐ and sex‐dependent alterations in primary somatosensory cortex neuronal calcium network dynamics during locomotion.

Published in:

Aging Cell, 2023, v. 22, n. 8, p. 1, doi. 10.1111/acel.13898

By:

Case, Sami L.;
Lin, Ruei‐Lung;
Thibault, Olivier

Publication type:

Article

Sensitivity of the S1 neuronal calcium network to insulin and Bay‐K 8644 in vivo: Relationship to gait, motivation, and aging processes.

Published in:

Aging Cell, 2022, v. 21, n. 7, p. 1, doi. 10.1111/acel.13661

By:

Lin, Ruei‐Lung;
Frazier, Hilaree N.;
Anderson, Katie L.;
Case, Sami L.;
Ghoweri, Adam O.;
Thibault, Olivier

Publication type:

Article

Molecular elevation of insulin receptor signaling improves memory recall in aged Fischer 344 rats.

Published in:

Aging Cell, 2020, v. 19, n. 10, p. 1, doi. 10.1111/acel.13220

By:

Frazier, Hilaree N.;
Anderson, Katie L.;
Ghoweri, Adam O.;
Lin, Ruei-Lung;
Hawkinson, Tara R.;
Popa, Gabriel J.;
Sompol, Pradoldej;
Mendenhall, Michael D.;
Norris, Christopher M.;
Thibault, Olivier

Publication type:

Article

Aged rats are hypo-responsive to acute restraint: implications for psychosocial stress in aging.

Published in:

Frontiers in Aging Neuroscience, 2014, v. 6, p. 1, doi. 10.3389/fnagi.2014.00013

By:

Buechel, Heather M.;
Popovic, Jelena;
Staggs, Kendra;
Anderson, Katie L.;
Thibault, Olivier;
Blalock, Eric M.

Publication type:

Article

In vivo imaging of prodromal hippocampus CA1 subfield oxidative stress in models of Alzheimer disease and Angelman syndrome.

Published in:

FASEB Journal, 2017, v. 31, n. 9, p. 4179, doi. 10.1096/fj.201700229R

By:

Berkowitz, Bruce A.;
Lenning, Jacob;
Khetarpal, Nikita;
Tran, Catherine;
Wu, Johnny Y.;
Berri, Ali M.;
Dernay, Kristin;
Haacke, E. Mark;
Shafie-Khorassani, Fatema;
Podolsky, Robert H.;
Gant, John C.;
Maimaiti, Shaniya;
Thibault, Olivier;
Murphy, Geoffrey G.;
Bennett, Brian M.;
Roberts, Robin

Publication type:

Article

Distinct modulation of voltage-gated and ligand-gated Ca2+ currents by PPAR-γ agonists in cultured hippocampal neurons.

Published in:

Journal of Neurochemistry, 2009, v. 109, n. 6, p. 1800, doi. 10.1111/j.1471-4159.2009.06107.x

By:

Pancani, Tristano;
Phelps, Jeremiah T.;
Searcy, James L.;
Kilgore, Michael W.;
Kuey-Chu Chen;
Porter, Nada M.;
Thibault, Olivier

Publication type:

Article

Nicotinic modulation of glutamate receptor function at nerve terminal level: a fine-tuning of synaptic signals.

Published in:

Frontiers in Pharmacology, 2015, v. 6, p. 1, doi. 10.3389/fphar.2015.00089

By:

Marchi, Mario;
Grilli, Massimo;
Pittaluga, Anna M.;
Bodhinathan, Karthik;
Thibault, Olivier

Publication type:

Article

Reversal of Glial and Neurovascular Markers of Unhealthy Brain Aging by Exercise in Middle-Aged Female Mice.

Published in:

PLoS ONE, 2011, v. 6, n. 10, p. 1, doi. 10.1371/journal.pone.0026812

By:

Latimer, Caitlin S.;
Searcy, James L.;
Bridges, Michael T.;
Brewer, Lawrence D.;
Popović, Jelena;
Blalock, Eric M.;
Landfield, Philip W.;
Thibault, Olivier;
Porter, Nada M.

Publication type:

Article

Deep Sleep and Parietal Cortex Gene Expression Changes Are Related to Cognitive Deficits with Age.

Published in:

PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0018387

By:

Buechel, Heather M.;
Popovic, Jelena;
Searcy, James L.;
Porter, Nada M.;
Thibault, Olivier;
Blalock, Eric M.

Publication type:

Article

Effects of Long-Term Pioglitazone Treatment on Peripheral and Central Markers of Aging.

Published in:

PLoS ONE, 2010, v. 5, n. 4, p. 1, doi. 10.1371/journal.pone.0010405

By:

Blalock, Eric M.;
Phelps, Jeremiah T.;
Pancani, Tristano;
Searcy, James L.;
Anderson, Katie L.;
Gant, John C.;
Popovic, Jelena;
Avdiushko, Margarita G.;
Cohen, Don A.;
Kuey-Chu Chen;
Porter, Nada M.;
Thibault, Olivier

Publication type:

Article

Astrocyte Ca2+ dysregulation and neurovascular coupling deficits in a diet‐based mouse model of small cerebral vessel disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080450

By:

Weiss, Blaine E.;
Sompol, Pradoldej M;
Gant, John C;
Lin, Ruei‐Lung;
Nelson, Peter T;
Thibault, Olivier;
Wilcock, Donna M.;
Norris, Christopher M.

Publication type:

Article

Perturbed astrocyte Ca2+ signaling in a diet‐based mouse model of small cerebral vessel disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.069404

By:

Norris, Christopher M;
Sompol, Pradoldej M;
Weiss, Blaine E.;
Gant, Christopher C;
Wilcock, Donna M;
Lin, Ruei‐Lung;
Thibault, Olivier

Publication type:

Article

Astrocyte activation and neurovascular function in a diet‐based model of vascular contributions to cognitive impairment and dementia (VCID): Molecular and cell biology/vascular factors.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043618

By:

Sompol, Pradoldej;
Edelmann, Stephanie E.;
Lin, Ruei‐Lung;
Gant, Christopher C.;
Kraner, Susan D.;
Weiss, Blaine E.;
Farr, N. Drew;
Gollihue, Jenna L.;
Thibault, Olivier;
Wilcock, Donna M.;
Norris, Christopher M.

Publication type:

Article

F1‐07‐02: ASTROCYTE ACTIVATION AND HIPPOCAMPAL SYNAPTIC IMPAIRMENTS IN MOUSE MODELS OF AMYLOID PATHOLOGY AND CEREBROVASCULAR DYSFUNCTION.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P188, doi. 10.1016/j.jalz.2019.06.4394

By:

Sompol, Pradoldej;
Kraner, Susan D.;
Gollihue, Jenna L.;
Thibault, Olivier;
Wilcock, Donna M.;
Norris, Chris M.

Publication type:

Article

Long-term effects of simvastatin and atorvastatin on a rat model of normal brain aging

Published in:

2009

By:

Searcy, James L.;
Latimer, Caitlin S.;
Thibault, Olivier;
Blalock, Eric M.;
Chen, Kuey-Chu;
Kadish, Inga;
Landfeild, Philip W.;
Porter, Nada M.

Publication type:

Abstract

P2-463: LXR agonist treatment of a transgenic mouse model of Alzheimer's disease: Effects on behavioral, electrophysiological and immunohistochemical markers

Published in:

2008

By:

Searcy, James L.;
Phelps, Jeremiah T.;
Blalock, Eric M.;
Dowling, Amy L.S.;
Chen, Kuey-Chu C.;
Landfield, Philip W.;
Thibault, Olivier;
Kadish, Inga;
Porter, Nada M.

Publication type:

Abstract

P2-457: Effect of chronic treatment with the PPAR-G agonist, pioglitazone, in a triple transgenic model of Alzheimer's disease

Published in:

2008

By:

Phelps, Jeremiah T.;
Searcy, James L.;
Pancani, Tristano;
Blalock, Eric M.;
Chen, Kuey-Chu;
Porter, Nada M.;
Thibault, Olivier

Publication type:

Abstract

Long-Term Intranasal Insulin Aspart: A Profile of Gene Expression, Memory, and Insulin Receptors in Aged F344 Rats.

Published in:

2020

By:

Frazier, Hilaree N;
Ghoweri, Adam O;
Sudkamp, Emily;
Johnson, Eleanor S;
Anderson, Katie L;
Fox, Grant;
Vatthanaphone, Keomany;
Xia, Mengfan;
Lin, Ruei-Lung;
Hargis-Staggs, Kendra E;
Porter, Nada M;
Pauly, James R;
Blalock, Eric M;
Thibault, Olivier

Publication type:

journal article

Impact of Single or Repeated Dose Intranasal Zinc-free Insulin in Young and Aged F344 Rats on Cognition, Signaling, and Brain Metabolism.

Published in:

2017

By:

Anderson, Katie L.;
Frazier, Hilaree N.;
Maimaiti, Shaniya;
Bakshi, Vikas V.;
Majeed, Zana R.;
Brewer, Lawrence D.;
Porter, Nada M.;
Ai-Ling Lin;
Thibault, Olivier;
Lin, Ai-Ling

Publication type:

journal article

Intranasal Insulin Improves Age-Related Cognitive Deficits and Reverses Electrophysiological Correlates of Brain Aging.

Published in:

2016

By:

Maimaiti, Shaniya;
Anderson, Katie L.;
DeMoll, Chris;
Brewer, Lawrence D.;
Rauh, Benjamin A.;
Gant, John C.;
Blalock, Eric M.;
Porter, Nada M.;
Thibault, Olivier

Publication type:

journal article

Works matching AU Thibault, Olivier

Elevating Insulin Signaling Using a Constitutively Active Insulin Receptor Increases Glucose Metabolism and Expression of GLUT3 in Hippocampal Neurons.

FK506-Binding Protein 12.6/lb, a Negative Regulator of [Ca<sup>2+</sup>], Rescues Memory and Restores Genomic Regulation in the Hippocampus of Aging Rats.

Reversal of Aging-Related Neuronal Ca<sup>2+</sup> Dysregulation and Cognitive Impairment by Delivery of a Transgene Encoding FK506-Binding Protein 12.6/1b to the Hippocampus.

Deciphering the Relationship Between Astrocyte Calcium Signaling, Neurovascular Coupling, and Cerebrovascular Function in Alzheimer's Disease.

Astrovascular coupling in the somatosensory cortex of an animal model of amyloidosis at rest and during ambulation.

Astrocyte selective insulin receptor knockout in the 5xFAD model of amyloidosis.

Astrocyte calcium dysregulation and cerebrovascular impairments in the 5XFAD mouse model of familial Alzheimer's disease.

Low‐Frequency Oscillations During Resting and Task Differentially Associate with Working Memory Performance in Older Adults.

Falling Short: The Contribution of Central Insulin Receptors to Gait Dysregulation in Brain Aging.

Hippocampal Expression Analyses Reveal Selective Association of Immediate-Early, Neuroenergetic, and Myelinogenic Pathways with Cognitive Impairment in Aged Rats.

Early and Simultaneous Emergence of Multiple Hippocampal Biomarkers of Aging Is Mediated by Ca<sup>2+</sup>-Induced Ca<sup>2+</sup> Release.

Targeting Astrocyte Signaling Alleviates Cerebrovascular and Synaptic Function Deficits in a Diet-Based Mouse Model of Small Cerebral Vessel Disease.

Disrupting Function of FK506-Binding Protein 1b/12.6 Induces the Ca<sup>2+</sup>-Dysregulation Aging Phenotype in Hippocampal Neurons.

Aging-Related Gene Expression in Hippocampus Proper Compared with Dentate Gyrus Is Selectively Associated with Metabolic Syndrome Variables in Rhesus Monkeys.

Hippocampal and Cognitive Aging across the Lifespan: A Bioenergetic Shift Precedes and Increased Cholesterol Trafficking Parallels Memory Impairment.

Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store.

BRD4 modulates vulnerability of triple-negative breast cancer to targeting of integrin-dependent signaling pathways.

Age‐ and sex‐dependent alterations in primary somatosensory cortex neuronal calcium network dynamics during locomotion.

Sensitivity of the S1 neuronal calcium network to insulin and Bay‐K 8644 in vivo: Relationship to gait, motivation, and aging processes.

Molecular elevation of insulin receptor signaling improves memory recall in aged Fischer 344 rats.

Aged rats are hypo-responsive to acute restraint: implications for psychosocial stress in aging.

In vivo imaging of prodromal hippocampus CA1 subfield oxidative stress in models of Alzheimer disease and Angelman syndrome.

Distinct modulation of voltage-gated and ligand-gated Ca<sup>2+</sup> currents by PPAR-γ agonists in cultured hippocampal neurons.

Nicotinic modulation of glutamate receptor function at nerve terminal level: a fine-tuning of synaptic signals.

Reversal of Glial and Neurovascular Markers of Unhealthy Brain Aging by Exercise in Middle-Aged Female Mice.

Deep Sleep and Parietal Cortex Gene Expression Changes Are Related to Cognitive Deficits with Age.

Effects of Long-Term Pioglitazone Treatment on Peripheral and Central Markers of Aging.

Astrocyte Ca2+ dysregulation and neurovascular coupling deficits in a diet‐based mouse model of small cerebral vessel disease.

Perturbed astrocyte Ca2+ signaling in a diet‐based mouse model of small cerebral vessel disease.

Astrocyte activation and neurovascular function in a diet‐based model of vascular contributions to cognitive impairment and dementia (VCID): Molecular and cell biology/vascular factors.

F1‐07‐02: ASTROCYTE ACTIVATION AND HIPPOCAMPAL SYNAPTIC IMPAIRMENTS IN MOUSE MODELS OF AMYLOID PATHOLOGY AND CEREBROVASCULAR DYSFUNCTION.

Long-term effects of simvastatin and atorvastatin on a rat model of normal brain aging

P2-463: LXR agonist treatment of a transgenic mouse model of Alzheimer's disease: Effects on behavioral, electrophysiological and immunohistochemical markers

P2-457: Effect of chronic treatment with the PPAR-G agonist, pioglitazone, in a triple transgenic model of Alzheimer's disease

Long-Term Intranasal Insulin Aspart: A Profile of Gene Expression, Memory, and Insulin Receptors in Aged F344 Rats.

Impact of Single or Repeated Dose Intranasal Zinc-free Insulin in Young and Aged F344 Rats on Cognition, Signaling, and Brain Metabolism.

Intranasal Insulin Improves Age-Related Cognitive Deficits and Reverses Electrophysiological Correlates of Brain Aging.