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Estradiol improves behavior in FAD transgenic mice that express APOE3 but not APOE4 after ovariectomy.
- Published in:
- Frontiers in Endocrinology, 2024, p. 1, doi. 10.3389/fendo.2024.1374825
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- Article
Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39444-y
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- Publication type:
- Article
Structure–Activity Relationships and Transcriptomic Analysis of Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors.
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- Antioxidants, 2022, v. 11, n. 2, p. 220, doi. 10.3390/antiox11020220
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- Publication type:
- Article
Systemic Candesartan Treatment Modulates Behavior, Synaptic Protein Levels, and Neuroinflammation in Female Mice That Express Human APOE4.
- Published in:
- Frontiers in Neuroscience, 2021, v. 14, p. N.PAG, doi. 10.3389/fnins.2021.628403
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- Article
Evidence for distinct mechanisms of small molecule inhibitors of filoviral entry.
- Published in:
- PLoS Pathogens, 2021, v. 17, n. 2, p. 1, doi. 10.1371/journal.ppat.1009312
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- Article
Synthesis of α‐Ketoamide‐Based Stereoselective Calpain‐1 Inhibitors as Neuroprotective Agents.
- Published in:
- ChemMedChem, 2020, v. 15, n. 23, p. 2280, doi. 10.1002/cmdc.202000385
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- Article
Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons.
- Published in:
- 2020
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- Publication type:
- journal article
Phase 1 study of TTC-352 in patients with metastatic breast cancer progressing on endocrine and CDK4/6 inhibitor therapy.
- Published in:
- Breast Cancer Research & Treatment, 2020, v. 183, n. 3, p. 617, doi. 10.1007/s10549-020-05787-z
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- Publication type:
- Article
G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer.
- Published in:
- Breast Cancer Research & Treatment, 2020, v. 180, n. 3, p. 635, doi. 10.1007/s10549-020-05575-9
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- Article
Soluble guanylyl cyclase is a critical regulator of migraine-associated pain.
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- 2018
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- Publication type:
- journal article
Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Amine-based Histone Deacetylase Inhibitors.
- Published in:
- ChemMedChem, 2017, v. 12, n. 24, p. 2030, doi. 10.1002/cmdc.201700449
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- Publication type:
- Article
Time-Gated Detection of Cystathionine γ-Lyase Activity and Inhibition with a Selective, Luminogenic Hydrogen Sulfide Sensor.
- Published in:
- Chemistry - A European Journal, 2017, v. 23, n. 4, p. 752, doi. 10.1002/chem.201604786
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- Publication type:
- Article
Frontispiece: Time-Gated Detection of Cystathionine γ-Lyase Activity and Inhibition with a Selective, Luminogenic Hydrogen Sulfide Sensor.
- Published in:
- Chemistry - A European Journal, 2017, v. 23, n. 4, p. n/a, doi. 10.1002/chem.201780462
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- Publication type:
- Article
A multifunctional therapeutic approach to disease modification in multiple familial mouse models and a novel sporadic model of Alzheimer's disease.
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- Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0103-6
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- Publication type:
- Article
Correction: The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development.
- Published in:
- 2016
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- Correction Notice
The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development.
- Published in:
- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 12, p. 1, doi. 10.1371/journal.pntd.0004279
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- Article
A novel aspirin prodrug inhibits NFκB activity and breast cancer stem cell properties.
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- 2015
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- Publication type:
- journal article
Re-engineering a neuroprotective, clinical drug as a procognitive agent with high in vivo potency and with GABAA potentiating activity for use in dementia.
- Published in:
- 2015
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- Publication type:
- journal article
Cover Picture: A Chimeric SERM-Histone Deacetylase Inhibitor Approach to Breast Cancer Therapy (ChemMedChem 3/2014).
- Published in:
- ChemMedChem, 2014, v. 9, n. 3, p. 413, doi. 10.1002/cmdc.201490005
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- Publication type:
- Article
A Chimeric SERM-Histone Deacetylase Inhibitor Approach to Breast Cancer Therapy.
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- ChemMedChem, 2014, v. 9, n. 3, p. 602, doi. 10.1002/cmdc.201300270
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- Publication type:
- Article
Discovery of neuroprotective soluble guanylate cyclase modulators (GCMs) aciting via NO/GC/ cGMP/CREB pathway.
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- 2013
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- Publication type:
- Abstract
NO/cGMP/pCREB re-activation reverses cognition deficits and attenuates amyloid-β neuropathology in transgenic models of Alzheimer's disease.
- Published in:
- 2013
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- Publication type:
- Abstract
An NO Donor Approach to Neuroprotective and Procognitive Estrogen Therapy Overcomes Loss of NO Synthase Function and Potentially Thrombotic Risk.
- Published in:
- PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0070740
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- Publication type:
- Article
Raloxifene and Desmethylarzoxifene Block Estrogen-Induced Malignant Transformation of Human Breast Epithelial Cells.
- Published in:
- PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0027876
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- Publication type:
- Article
Selective modulation of amyloid-β peptide degradation by flurbiprofen, fenofibrate, and related compounds regulates Aβ levels.
- Published in:
- Journal of Neurochemistry, 2009, v. 111, n. 3, p. 683, doi. 10.1111/j.1471-4159.2009.06355.x
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- Publication type:
- Article
NO-flurbiprofen reduces amyloid-β, is neuroprotective in cell culture, and enhances cognition in response to cholinergic blockade.
- Published in:
- Journal of Neurochemistry, 2009, v. 111, n. 3, p. 766, doi. 10.1111/j.1471-4159.2009.06353.x
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- Publication type:
- Article
Structure-Activity Relationships for a Family of Benzothiophene Selective Estrogen Receptor Modulators Including Raloxifene and Arzoxifene.
- Published in:
- ChemMedChem, 2007, v. 2, n. 10, p. 1520, doi. 10.1002/cmdc.200700104
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- Publication type:
- Article
Cognitive Deficits in Rats after Forebrain Cholinergic Depletion are Reversed by a Novel NO Mimetic Nitrate Ester.
- Published in:
- Neuropsychopharmacology, 2007, v. 32, n. 3, p. 505, doi. 10.1038/sj.npp.1301054
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- Publication type:
- Article
Photochemical reactions of thiols with organic nitrates Oxygen atom transfer via a thionitrate.
- Published in:
- Canadian Journal of Chemistry, 2006, v. 84, n. 4, p. 709, doi. 10.1139/v06-056
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- Publication type:
- Article
Novel nitrates as NO mimetics directed at Alzheimer's disease.
- Published in:
- Journal of Alzheimer's Disease, 2004, v. 6, p. S75
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- Publication type:
- Article
Alkali metal ion catalysis in nucleophilic displacement by ethoxide ion on p-nitrophenyl phenylphosphonate: Evidence for multiple metal ion catalysis¹.
- Published in:
- Canadian Journal of Chemistry, 2003, v. 81, n. 1, p. 53, doi. 10.1139/v02-202
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- Publication type:
- Article
Inhibition of phosphatidylinositol-specific phospholipase C: Studies on synthetic substrates, inhibitors and a synthetic enzyme.
- Published in:
- Journal of Molecular Recognition, 1996, v. 9, n. 2, p. 197, doi. 10.1002/(SICI)1099-1352(199603)9:2<197::AID-JMR263>3.0.CO;2-X
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- Publication type:
- Article