Works by Thangavel, Saravanabhavan

Results: 17

Homology-directed gene-editing approaches for hematopoietic stem and progenitor cell gene therapy.
Published in:
Stem Cell Research & Therapy, 2021, v. 12, n. 1, p. 1, doi. 10.1186/s13287-021-02565-6
By:
- Azhagiri, Manoj Kumar K.;
- Babu, Prathibha;
- Venkatesan, Vigneshwaran;
- Thangavel, Saravanabhavan
Publication type:
Article
Identification of RECQ1-regulated transcriptome uncovers a role of RECQ1 in regulation of cancer cell migration and invasion.
Published in:
Cell Cycle, 2014, v. 13, n. 15, p. 2431, doi. 10.4161/cc.29419
By:
- Xiao Ling Li;
- Xing Lu;
- Parvathaneni, Swetha;
- Bilke, Sven;
- Hongen Zhang;
- Thangavel, Saravanabhavan;
- Vindigni, Alessandro;
- Hara, Toshifumi;
- Yuelin Zhu;
- Meltzer, Paul S.;
- Lal, Ashish;
- Sharma, Sudha
Publication type:
Article
XLF and H2AX function in series to promote replication fork stability.
Published in:
Journal of Cell Biology, 2019, v. 218, n. 7, p. 2113, doi. 10.1083/jcb.201808134
By:
- Bo-Ruei Chen;
- Quinet, Annabel;
- Byrum, Andrea K.;
- Jackson, Jessica;
- Berti, Matteo;
- Thangavel, Saravanabhavan;
- Bredemeyer, Andrea L.;
- Hindi, Issa;
- Mosammaparast, Nima;
- Tyler, Jessica K.;
- Vindigni, Alessandro;
- Sleckman, Barry P.
Publication type:
Article
DNA2 drives processing and restart of reversed replication forks in human cells.
Published in:
Journal of Cell Biology, 2015, v. 208, n. 5, p. 545, doi. 10.1083/jcb.201406100
By:
- Thangavel, Saravanabhavan;
- Berti, Matteo;
- Levikova, Maryna;
- Pinto, Cosimo;
- Gomathinayagam, Shivasankari;
- Vujanovic, Marko;
- Zellweger, Ralph;
- Moore, Hayley;
- Eu Han Lee;
- Hendrickson, Eric A.;
- Cejka, Petr;
- Stewart, Sheila;
- Lopes, Massimo;
- Vindigni, Alessandro
Publication type:
Article
Correlating the differences in the receptor binding domain of SARS-CoV-2 spike variants on their interactions with human ACE2 receptor.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-35070-2
By:
- Mahalingam, Gokulnath;
- Arjunan, Porkizhi;
- Periyasami, Yogapriya;
- Dhyani, Ajay Kumar;
- Devaraju, Nivedita;
- Rajendiran, Vignesh;
- Christopher, Abisha Crystal;
- KT, Ramya Devi;
- Dhanasingh, Immanuel;
- Thangavel, Saravanabhavan;
- Murugesan, Mohankumar;
- Moorthy, Mahesh;
- Srivastava, Alok;
- Marepally, Srujan
Publication type:
Article
Direct Generation of Immortalized Erythroid Progenitor Cell Lines from Peripheral Blood Mononuclear Cells.
Published in:
Cells (2073-4409), 2021, v. 10, n. 3, p. 523, doi. 10.3390/cells10030523
By:
- Bagchi, Abhirup;
- Nath, Aneesha;
- Thamodaran, Vasanth;
- Ijee, Smitha;
- Palani, Dhavapriya;
- Rajendiran, Vignesh;
- Venkatesan, Vigneshwaran;
- Datari, Phaneendra;
- Pai, Aswin Anand;
- Janet, Nancy Beryl;
- Balasubramanian, Poonkuzhali;
- Nakamura, Yukio;
- Srivastava, Alok;
- Mohankumar, Kumarasamypet Murugesan;
- Thangavel, Saravanabhavan;
- Velayudhan, Shaji R.;
- Kalyuzhny, Alexander E.
Publication type:
Article
The CCR5 Gene Edited CD34<sup>+</sup>CD90<sup>+</sup> Hematopoietic Stem Cell Population Serves as an Optimal Graft Source for HIV Gene Therapy.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.792684
By:
- Karuppusamy, Karthik V.;
- Demosthenes, John Paul;
- Venkatesan, Vigneshwaran;
- Christopher, Abisha Crystal;
- Babu, Prathibha;
- Azhagiri, Manojkumar K.;
- Jacob, Annlin;
- Ramalingam, Veena Vadhini;
- Rangaraj, Sumathi;
- Murugesan, Mohankumar Kumarasamypet;
- Marepally, Srujan Kumar;
- Varghese, George M.;
- Srivastava, Alok;
- Kannangai, Rajesh;
- Thangavel, Saravanabhavan
Publication type:
Article
Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replication.
Published in:
EMBO Journal, 2010, v. 29, n. 18, p. 3140, doi. 10.1038/emboj.2010.186
By:
- Dongyi Xu;
- Muniandy, Parameswary;
- Leo, Elisabetta;
- Jinhu Yin;
- Thangavel, Saravanabhavan;
- Xi Shen;
- Ii, Miki;
- Agama, Keli;
- Rong Guo;
- Fox, III, David;
- Meetei, Amom Ruhikanta;
- Wilson, Lauren;
- Nguyen, Huy;
- Weng, Nan-ping;
- Brill, Steven J.;
- Lei Li;
- Vindigni, Alessandro;
- Pommier, Yves;
- Seidman, Michael;
- Weidong Wang
Publication type:
Article
Enhanced fetal hemoglobin production via dual-beneficial mutation editing of the HBG promoter in hematopoietic stem and progenitor cells for β-hemoglobinopathies.
Published in:
Stem Cell Research & Therapy, 2024, v. 15, n. 1, p. 1, doi. 10.1186/s13287-024-04117-0
By:
- Chandraprabha, Prathibha Babu;
- Azhagiri, Manoj Kumar K.;
- Venkatesan, Vigneshwaran;
- Magis, Wendy;
- Prasad, Kirti;
- Suresh, Sevanthy;
- Pai, Aswin Anand;
- Marepally, Srujan;
- Srivastava, Alok;
- Mohankumar, Kumarasamypet Murugesan;
- Martin, David I. K.;
- Thangavel, Saravanabhavan
Publication type:
Article
Manipulation of Developmental Gamma-Globin Gene Expression: an Approach for Healing Hemoglobinopathies.
Published in:
Molecular & Cellular Biology, 2021, v. 41, n. 1, p. 1, doi. 10.1128/MCB.00253-20
By:
- Venkatesan, Vigneshwaran;
- Srinivasan, Saranya;
- Babu, Prathibha;
- Thangavel, Saravanabhavan
Publication type:
Article
CRISPR-Cas9 Probing of Infectious Diseases and Genetic Disorders.
Published in:
2019
By:
- Ramalingam, Sivaprakash;
- Thangavel, Saravanabhavan
Publication type:
journal article
Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin.
Published in:
eLife, 2022, p. 1, doi. 10.7554/eLife.65421
By:
- Ravi, Nithin Sam;
- Wienert, Beeke;
- Wyman, Stacia K.;
- Bell, Henry William;
- George, Anila;
- Mahalingam, Gokulnath;
- Vu, Jonathan T.;
- Prasad, Kirti;
- Bandlamudi, Bhanu Prasad;
- Devaraju, Nivedhitha;
- Rajendiran, Vignesh;
- Syedbasha, Nazar;
- Pai, Aswin Anand;
- Yukio Nakamura;
- Kurita, Ryo;
- Narayanasamy, Muthuraman;
- Balasubramanian, Poonkuzhali;
- Thangavel, Saravanabhavan;
- Marepally, Srujan;
- Velayudhan, Shaji R.
Publication type:
Article
Endocytosis as a critical regulator of hematopoietic stem cell fate —implications for hematopoietic stem cell and gene therapy.
Published in:
Stem Cell Research & Therapy, 2024, v. 15, n. 1, p. 1, doi. 10.1186/s13287-024-03927-6
By:
- Babu Chandraprabha, Prathibha;
- Thangavel, Saravanabhavan
Publication type:
Article
Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition.
Published in:
Nature Structural & Molecular Biology, 2013, v. 20, n. 3, p. 347, doi. 10.1038/nsmb.2501
By:
- Berti, Matteo;
- Chaudhuri, Arnab Ray;
- Thangavel, Saravanabhavan;
- Gomathinayagam, Shivasankari;
- Kenig, Sasa;
- Vujanovic, Marko;
- Odreman, Federico;
- Glatter, Timo;
- Graziano, Simona;
- Mendoza-Maldonado, Ramiro;
- Marino, Francesca;
- Lucic, Bojana;
- Biasin, Valentina;
- Gstaiger, Matthias;
- Aebersold, Ruedi;
- Sidorova, Julia M;
- Monnat, Raymond J;
- Lopes, Massimo;
- Vindigni, Alessandro
Publication type:
Article
Erythroid lineage-specific lentiviral RNAi vectors suitable for molecular functional studies and therapeutic applications.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-13783-0
By:
- Bagchi, Abhirup;
- Devaraju, Nivedhitha;
- Chambayil, Karthik;
- Rajendiran, Vignesh;
- Venkatesan, Vigneshwaran;
- Sayed, Nilofer;
- Pai, Aswin Anand;
- Nath, Aneesha;
- David, Ernest;
- Nakamura, Yukio;
- Balasubramanian, Poonkuzhali;
- Srivastava, Alok;
- Thangavel, Saravanabhavan;
- Mohankumar, Kumarasamypet M.;
- Velayudhan, Shaji R.
Publication type:
Article
Optimization of SARS-CoV-2 Pseudovirion Production in Lentivirus Backbone With a Novel Liposomal System.
Published in:
Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.840727
By:
- Mahalingam, Gokulnath;
- Rachamalla, Hari Krishnareddy;
- Arjunan, Porkizhi;
- Periyasami, Yogapriya;
- M, Salma;
- Thangavel, Saravanabhavan;
- Mohankumar, Kumarasamypet M.;
- Moorthy, Mahesh;
- Velayudhan, Shaji R.;
- Srivastava, Alok;
- Marepally, Srujan
Publication type:
Article
Human RECQ1 and RECQ4 Helicases Play Distinct Roles in DNA Replication Initiation.
Published in:
Molecular & Cellular Biology, 2010, v. 30, n. 6, p. 7, doi. 10.1128/MCB.01290-09
By:
- Thangavel, Saravanabhavan;
- Mendoza-Maldonado, Ramiro;
- Tissino, Erika;
- Sidorova, Julia M.;
- Jinhu Yin;
- Weidong Wang;
- Monnat Jr., Raymond J.;
- Falaschi, Arturo;
- Vindigni, Alessandro
Publication type:
Article