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Inhibition of an Alzheimer's disease--associated form of necroptosis rescues neuronal death in mouse models.
Published in:
Science Translational Medicine, 2024, v. 16, n. 771, p. 1, doi. 10.1126/scitranslmed.adf5128
By:
- Koper, Marta J.;
- Moonen, Sebastiaan;
- Ronisz, Alicja;
- Ospitalieri, Simona;
- Callaerts-Vegh, Zsuzsanna;
- T'Syen, Dries;
- Rabe, Sabine;
- Staufenbiel, Matthias;
- De Strooper, Bart;
- Balusu, Sriram;
- Thal, Dietmar Rudolf
Publication type:
Article
Posterior Reversible Encephalopathy Syndrome in a Patient With Multiple System Atrophy.
Published in:
Movement Disorders Clinical Practice, 2017, v. 4, n. 5, p. 789, doi. 10.1002/mdc3.12495
By:
- Debray, Sarah;
- Van de Vondel, Saartje;
- Tousseyn, Thomas;
- Thal, Dietmar Rudolf;
- Dewil, Maarten
Publication type:
Article
Correction to: Different aspects of Alzheimer's disease-related amyloid β-peptide pathology and their relationship to amyloid positron emission tomography imaging and dementia.
Published in:
2020
By:
- Thal, Dietmar Rudolf;
- Ronisz, Alicja;
- Tousseyn, Thomas;
- Upadhaya, Ajeet Rijal;
- Balakrishnan, Karthikeyan;
- Vandenberghe, Rik;
- Vandenbulcke, Mathieu;
- von Arnim, Christine A. F.;
- Otto, Markus;
- Beach, Thomas G.;
- Lilja, Johan;
- Heurling, Kerstin;
- Chakrabarty, Aruna;
- Ismail, Azzam;
- Buckley, Christopher;
- Smith, Adrian P. L.;
- Kumar, Sathish;
- Farrar, Gill;
- Walter, Jochen
Publication type:
Correction Notice
Distinct molecular patterns of TDP-43 pathology in Alzheimer's disease: relationship with clinical phenotypes.
Published in:
Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-00934-5
By:
- Tomé, Sandra O.;
- Vandenberghe, Rik;
- Ospitalieri, Simona;
- Van Schoor, Evelien;
- Tousseyn, Thomas;
- Otto, Markus;
- von Arnim, Christine A. F.;
- Thal, Dietmar Rudolf
Publication type:
Article
Seeding, maturation and propagation of amyloid β-peptide aggregates in Alzheimer's disease.
Published in:
2022
By:
- Li, Xiaohang;
- Ospitalieri, Simona;
- Robberechts, Tessa;
- Hofmann, Linda;
- Schmid, Christina;
- Upadhaya, Ajeet Rijal;
- Koper, Marta J;
- Arnim, Christine A F von;
- Kumar, Sathish;
- Willem, Michael;
- Gnoth, Kathrin;
- Ramakers, Meine;
- Schymkowitz, Joost;
- Rousseau, Frederic;
- Walter, Jochen;
- Ronisz, Alicja;
- Balakrishnan, Karthikeyan;
- Thal, Dietmar Rudolf;
- Rijal Upadhaya, Ajeet;
- von Arnim, Christine A F
Publication type:
journal article
Co-pathologies in Alzheimer's disease: just multiple pathologies or partners in crime?
Published in:
2021
By:
- Tomé, Sandra O;
- Thal, Dietmar Rudolf
Publication type:
journal article
Monitoring the progression of Alzheimer's disease with τ-PET.
Published in:
2016
By:
- Thal, Dietmar Rudolf;
- Vandenberghe, Rik
Publication type:
journal article
Retina pathology as a target for biomarkers for Alzheimer's disease: Current status, ophthalmopathological background, challenges, and future directions.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 1, p. 728, doi. 10.1002/alz.13529
By:
- Alber, Jessica;
- Bouwman, Femke;
- den Haan, Jurre;
- Rissman, Robert A.;
- De Groef, Lies;
- Koronyo‐Hamaoui, Maya;
- Lengyel, Imre;
- Thal, Dietmar Rudolf
Publication type:
Article
Primary retinal tauopathy: A tauopathy with a distinct molecular pattern.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 1, p. 330, doi. 10.1002/alz.13424
By:
- Walkiewicz, Grzegorz;
- Ronisz, Alicja;
- Van Ginderdeuren, Rita;
- Lemmens, Sophie;
- Bouwman, Femke H.;
- Hoozemans, Jeroen J. M.;
- Morrema, Tjado H. J.;
- Rozemuller, Annemieke J.;
- Hart de Ruyter, Frederique J.;
- De Groef, Lies;
- Stalmans, Ingeborg;
- Thal, Dietmar Rudolf
Publication type:
Article
Ponatinib and dabrafenib reduce the accumulation of necroptosis‐related proteins and neuronal loss in APP23xTAU58 mice.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.077757
By:
- Koper, Marta J;
- Moonen, Sebastiaan;
- Ronisz, Alicja;
- Ospitalieri, Simona;
- Rabe, Sabine;
- Staufenbiel, Matthias;
- De Strooper, Bart;
- Balusu, Sriram;
- Thal, Dietmar Rudolf
Publication type:
Article
A retinal tauopathy with a characteristic molecular pattern points to the existence of a "Primary retinal tauopathy".
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076166
By:
- Walkiewicz, Grzegorz;
- Ronisz, Alicja;
- Van Ginderdeuren, Rita;
- Lemmens, Sophie;
- Bouwman, Femke H.;
- Hoozemans, Jeroen;
- Morrema, Tjado;
- Rozemuller, Annemieke J.M.;
- de Ruyter, Frederique J. Hart;
- De Groef, Lies;
- Stalmans, Ingeborg;
- Thal, Dietmar Rudolf
Publication type:
Article
Single nucleotide polymorphisms linked to Alzheimer's disease are associated with distinct neuropathological phenotypes.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078165
By:
- Laureyssen, Celeste;
- Gawor, Klara;
- Van Dongen, Jasper;
- Kucukali, Fahri;
- Koper, Marta J;
- Ronisz, Alicja;
- Otto, Markus;
- von Arnim, Christine;
- Van Damme, Philip;
- Vandenberghe, Rik;
- Thal, Dietmar Rudolf;
- Sleegers, Kristel
Publication type:
Article
Association of hippocampal neuron loss, pTDP‐43, and Alzheimer's disease pathology with the presence of cerebral Lewy bodies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077833
By:
- Gawor, Klara;
- Tomé, Sandra O.;
- Ronisz, Alicja;
- Ospitalieri, Simona;
- Vandenberghe, Rik;
- von Arnim, Christina;
- Otto, Markus;
- Thal, Dietmar Rudolf
Publication type:
Article
The impact of co‐morbid LATE‐NC pathology in Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.073996
By:
- Tomé, Sandra O.;
- Tsaka, Grigoria;
- Ronisz, Alicja;
- Ospitalieri, Simona;
- Gawor, Klara;
- von Arnim, Christina;
- Otto, Markus;
- Vandenberghe, Rik;
- Schymkowitz, Joost;
- Rousseau, Frederic;
- Thal, Dietmar Rudolf
Publication type:
Article
Single nucleotide polymorphisms linked to Alzheimer's disease are associated with distinct neuropathological phenotypes.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078165
By:
- Laureyssen, Celeste;
- Gawor, Klara;
- Van Dongen, Jasper;
- Kucukali, Fahri;
- Koper, Marta J;
- Ronisz, Alicja;
- Otto, Markus;
- von Arnim, Christine;
- Van Damme, Philip;
- Vandenberghe, Rik;
- Thal, Dietmar Rudolf;
- Sleegers, Kristel
Publication type:
Article
Association of hippocampal neuron loss, pTDP‐43, and Alzheimer's disease pathology with the presence of cerebral Lewy bodies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077833
By:
- Gawor, Klara;
- Tomé, Sandra O.;
- Ronisz, Alicja;
- Ospitalieri, Simona;
- Vandenberghe, Rik;
- von Arnim, Christina;
- Otto, Markus;
- Thal, Dietmar Rudolf
Publication type:
Article
The impact of co‐morbid LATE‐NC pathology in Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.073996
By:
- Tomé, Sandra O.;
- Tsaka, Grigoria;
- Ronisz, Alicja;
- Ospitalieri, Simona;
- Gawor, Klara;
- von Arnim, Christina;
- Otto, Markus;
- Vandenberghe, Rik;
- Schymkowitz, Joost;
- Rousseau, Frederic;
- Thal, Dietmar Rudolf
Publication type:
Article
Stages of retinal tauopathy and its relation to age and non‐AD retinal pathologies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.064086
By:
- Thal, Dietmar Rudolf;
- Ronisz, Alicja;
- Van Ginderdeuren, Rita;
- Lemmens, Sophie;
- Stalmans, Ingeborg;
- De Groef, Lies;
- Walkiewicz, Grzegorz
Publication type:
Article
Neuronal loss of the nucleus basalis of Meynert in primary progressive aphasia is associated with Alzheimer's disease neuropathological changes.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 4, p. 1440, doi. 10.1002/alz.12794
By:
- Schaeverbeke, Jolien;
- Tomé, Sandra O.;
- Ronisz, Alicja;
- Ospitalieri, Simona;
- von Arnim, Christine A. F.;
- Otto, Markus;
- Vandenberghe, Rik;
- Thal, Dietmar Rudolf
Publication type:
Article
Astrocytes mediate neuronal network hyperactivity in early AD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.068629
By:
- Shah, Disha;
- Gsell, Willy;
- Wahis, Jérôme;
- Luckett, Emma S.;
- Jamoulle, Tarik;
- Preman, Pranav;
- Moechars, Daan;
- Craessaerts, Katleen;
- Horré, Katrien;
- Hendrickx, Véronique;
- Jaspers, Tom;
- Wolfs, Leen;
- Vermaercke, Ben;
- Fiers, Mark;
- Holt, Matthew;
- Vegh, Zsuzsanna;
- Thal, Dietmar Rudolf;
- D'Hooge, Rudi;
- Vandenberghe, Rik;
- Himmelreich, Uwe
Publication type:
Article
Sequence of proteome profiles in preclinical and symptomatic Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 6, p. 946, doi. 10.1002/alz.12345
By:
- Li, Xiaohang;
- Tsolis, Konstantinos C.;
- Koper, Marta J.;
- Ronisz, Alicja;
- Ospitalieri, Simona;
- von Arnim, Christine A.F.;
- Vandenberghe, Rik;
- Tousseyn, Thomas;
- Scheuerle, Angelika;
- Economou, Anastassios;
- Carpentier, Sebastien;
- Otto, Markus;
- Thal, Dietmar Rudolf
Publication type:
Article
Hierarchical involvement of molecular players in human neocortex in the course of preclinical and symptomatic Alzheimer's disease: Developing topics.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.047351
By:
- Li, Xiaohang;
- Tsolis, Konstantinos C;
- Koper, Marta J;
- Ronisz, Alicja;
- Ospitalieri, Simona;
- von Arnim, Christine;
- Otto, Markus;
- Vandenberghe, Rik;
- Tousseyn, Thomas;
- Scheuerle, Angelika;
- Economou, Tassos;
- Carpentier, Sebastien;
- Thal, Dietmar Rudolf
Publication type:
Article
Classification of 18F‐flutemetamol scans using machine learning with neuropathology as standard of truth: Neuroimaging / Optimal neuroimaging measures for tracking disease progression.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044550
By:
- Reinartz, Mariska;
- Farrar, Gill;
- Buckley, Christopher;
- Smith, Adrian;
- Thal, Dietmar Rudolf;
- Dupont, Patrick;
- Vandenberghe, Rik
Publication type:
Article
Two distinct molecular patterns of TDP‐43 pathology in cases with Alzheimer's disease pathology: Human neuropathology/proteinopathies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043074
By:
- Tomé, Sandra;
- Vandenberghe, Rik;
- Ospitalieri, Simona;
- Van Schoor, Evelien;
- Tousseyn, Thomas;
- Otto, Markus;
- von Arnim, Christine;
- Thal, Dietmar Rudolf
Publication type:
Article
Chimeric models to analyze human neuron and astroglia responses in Alzheimer's disease: Molecular and cell biology/stem cells, iPS cells.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042678
By:
- Arranz, Amaia M.;
- Preman, Pranav;
- T.C.W., Julia;
- Snellinx, An;
- Calafate, Sara;
- Thal, Dietmar Rudolf;
- Goate, Alison M.;
- De Strooper, Bart
Publication type:
Article
Alzheimer's disease‐related necroptotic pathology: An exclusive presence of the necrosome in granulovacuolar degeneration inclusions in human and transgenic mouse brains: Molecular and cell biology/neuronal cell death mechanisms (i.e. apoptosis).
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042460
By:
- Koper, Marta J.;
- Van Schoor, Evelien;
- Ospitalieri, Simona;
- Vandenberghe, Rik;
- Vandenbulcke, Mathieu;
- von Arnim, Christine;
- Tousseyn, Thomas;
- Reichwald, Julia;
- Rabe, Sabine;
- Staufenbiel, Matthias;
- Balusu, Sriram;
- De Strooper, Bart;
- Thal, Dietmar Rudolf
Publication type:
Article
Impact of the presence of AβN3pE and AβpSer8 in Aβ aggregates on the induction of Aβ seeding and spreading in the brains of APP23 mice: Human neuropathology/amyloid.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.038224
By:
- Robberechts, Tessa;
- Ronisz, Alicja;
- Ospitalieri, Simona;
- Koper, Marta J.;
- Kumar, Sathish;
- Walter, Jochen;
- Willem, Michael;
- Li, Xiaohang;
- Thal, Dietmar Rudolf
Publication type:
Article
Mapping the sequence specificity of heterotypic amyloid interactions enables the identification of aggregation modifiers.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28955-9
By:
- Louros, Nikolaos;
- Ramakers, Meine;
- Michiels, Emiel;
- Konstantoulea, Katerina;
- Morelli, Chiara;
- Garcia, Teresa;
- Moonen, Nele;
- D'Haeyer, Sam;
- Goossens, Vera;
- Thal, Dietmar Rudolf;
- Audenaert, Dominique;
- Rousseau, Frederic;
- Schymkowitz, Joost
Publication type:
Article
Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21972-0
By:
- Wettstein, Lukas;
- Weil, Tatjana;
- Conzelmann, Carina;
- Müller, Janis A.;
- Groß, Rüdiger;
- Hirschenberger, Maximilian;
- Seidel, Alina;
- Klute, Susanne;
- Zech, Fabian;
- Prelli Bozzo, Caterina;
- Preising, Nico;
- Fois, Giorgio;
- Lochbaum, Robin;
- Knaff, Philip Maximilian;
- Mailänder, Volker;
- Ständker, Ludger;
- Thal, Dietmar Rudolf;
- Schumann, Christian;
- Stenger, Steffen;
- Kleger, Alexander
Publication type:
Article
[18F]flutemetamol amyloid positron emission tomography in preclinical and symptomatic Alzheimer's disease: Specific detection of advanced phases of amyloid-β pathology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 8, p. 975, doi. 10.1016/j.jalz.2015.05.018
By:
- Thal, Dietmar Rudolf;
- Beach, Thomas G.;
- Zanette, Michelle;
- Heurling, Kerstin;
- Chakrabarty, Aruna;
- Ismail, Azzam;
- Smith, Adrian P.L.;
- Buckley, Christopher
Publication type:
Article
Role of free and exosomal tdp-43 as a diagnostic tool in neurodegenerative diseases.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2014, v. 10, p. P147, doi. 10.1016/j.jalz.2014.04.107
By:
- Feneberg, Emily;
- Otto, Markus;
- Steinacker, Petra;
- Lehnert, Stefan;
- Schneider, Anja;
- Linsenmeier, Miriam;
- Walther, Paul;
- Thal, Dietmar Rudolf;
- Ludolph, Albert
Publication type:
Article
National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2012, v. 8, n. 1, p. 1, doi. 10.1016/j.jalz.2011.10.007
By:
- Hyman, Bradley T.;
- Phelps, Creighton H.;
- Beach, Thomas G.;
- Bigio, Eileen H.;
- Cairns, Nigel J.;
- Carrillo, Maria C.;
- Dickson, Dennis W.;
- Duyckaerts, Charles;
- Frosch, Matthew P.;
- Masliah, Eliezer;
- Mirra, Suzanne S.;
- Nelson, Peter T.;
- Schneider, Julie A.;
- Thal, Dietmar Rudolf;
- Thies, Bill;
- Trojanowski, John Q.;
- Vinters, Harry V.;
- Montine, Thomas J.
Publication type:
Article
Impact of amyloid α aggregate maturation on antibody treatment in APP23 mice.
Published in:
Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 1, doi. 10.1186/s40478-015-0217-z
By:
- Balakrishnan, Karthikeyan;
- Upadhaya, Ajeet Rijal;
- Steinmetz, Julia;
- Reichwald, Julia;
- Abramowski, Dorothee;
- Fändrich, Marcus;
- Kumar, Sathish;
- Yamaguchi, Haruyasu;
- Walter, Jochen;
- Staufenbiel, Matthias;
- Thal, Dietmar Rudolf
Publication type:
Article
Local structural preferences in shaping tau amyloid polymorphism.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45429-2
By:
- Louros, Nikolaos;
- Wilkinson, Martin;
- Tsaka, Grigoria;
- Ramakers, Meine;
- Morelli, Chiara;
- Garcia, Teresa;
- Gallardo, Rodrigo;
- D'Haeyer, Sam;
- Goossens, Vera;
- Audenaert, Dominique;
- Thal, Dietmar Rudolf;
- Mackenzie, Ian R.;
- Rademakers, Rosa;
- Ranson, Neil A.;
- Radford, Sheena E.;
- Rousseau, Frederic;
- Schymkowitz, Joost
Publication type:
Article
Large- and Small-Fiber Neuropathy in Patients with Tarlov Cysts.
Published in:
Journal of Pain Research, 2022, v. 15, p. 193, doi. 10.2147/JPR.S342759
By:
- Hulens, Mieke;
- Bruyninckx, Frans;
- Thal, Dietmar Rudolf;
- Rasschaert, Ricky;
- Bervoets, Chris;
- Dankaerts, Wim
Publication type:
Article
Telomere Shortening Impairs Regeneration of the Olfactory Epithelium in Response to Injury but Not Under Homeostatic Conditions.
Published in:
PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0027801
By:
- Watabe-Rudolph, Masami;
- Begus-Nahrmann, Yvonne;
- Lechel, André;
- Rolyan, Harshvardhan;
- Scheithauer, Marc-Oliver;
- Rettinger, Gerhard;
- Thal, Dietmar Rudolf;
- Rudolph, Karl Lenhard
Publication type:
Article
Circadian sleep/wake-associated cells show dipeptide repeat protein aggregates in C9orf72-related ALS and FTLD cases.
Published in:
Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. 1, doi. 10.1186/s40478-019-0845-9
By:
- Dedeene, Lieselot;
- Van Schoor, Evelien;
- Vandenberghe, Rik;
- Van Damme, Philip;
- Poesen, Koen;
- Thal, Dietmar Rudolf
Publication type:
Article
Circadian sleep/wake-associated cells show dipeptide repeat protein aggregates in C9orf72-related ALS and FTLD cases.
Published in:
Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0845-9
By:
- Dedeene, Lieselot;
- Van Schoor, Evelien;
- Vandenberghe, Rik;
- Van Damme, Philip;
- Poesen, Koen;
- Thal, Dietmar Rudolf
Publication type:
Article
Different aspects of Alzheimer's disease-related amyloid β-peptide pathology and their relationship to amyloid positron emission tomography imaging and dementia.
Published in:
Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0837-9
By:
- Thal, Dietmar Rudolf;
- Ronisz, Alicja;
- Tousseyn, Thomas;
- Rijal Upadhaya, Ajeet;
- Balakrishnan, Karthikeyan;
- Vandenberghe, Rik;
- Vandenbulcke, Mathieu;
- von Arnim, Christine A. F.;
- Otto, Markus;
- Beach, Thomas G.;
- Lilja, Johan;
- Heurling, Kerstin;
- Chakrabarty, Aruna;
- Ismail, Azzam;
- Buckley, Christopher;
- Smith, Adrian P. L.;
- Kumar, Sathish;
- Farrar, Gill;
- Walter, Jochen
Publication type:
Article
Frontotemporal Lobar Degeneration Case with an N-Terminal TUBA4A Mutation Exhibits Reduced TUBA4A Levels in the Brain and TDP-43 Pathology.
Published in:
Biomolecules (2218-273X), 2022, v. 12, n. 3, p. 440, doi. 10.3390/biom12030440
By:
- Van Schoor, Evelien;
- Vandenbulcke, Mathieu;
- Bercier, Valérie;
- Vandenberghe, Rik;
- van der Zee, Julie;
- Van Broeckhoven, Christine;
- Otto, Markus;
- Hanseeuw, Bernard;
- Van Damme, Philip;
- Van Den Bosch, Ludo;
- Thal, Dietmar Rudolf
Publication type:
Article
A toxic gain-of-function mechanism in C9orf72 ALS impairs the autophagy-lysosome pathway in neurons.
Published in:
Acta Neuropathologica Communications, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40478-023-01648-0
By:
- Beckers, Jimmy;
- Tharkeshwar, Arun Kumar;
- Fumagalli, Laura;
- Contardo, Matilde;
- Van Schoor, Evelien;
- Fazal, Raheem;
- Thal, Dietmar Rudolf;
- Chandran, Siddharthan;
- Mancuso, Renzo;
- Van Den Bosch, Ludo;
- Van Damme, Philip
Publication type:
Article
Senescence-related impairment of autophagy induces toxic intraneuronal amyloid-β accumulation in a mouse model of amyloid pathology.
Published in:
Acta Neuropathologica Communications, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40478-023-01578-x
By:
- Suelves, Nuria;
- Saleki, Shirine;
- Ibrahim, Tasha;
- Palomares, Debora;
- Moonen, Sebastiaan;
- Koper, Marta J.;
- Vrancx, Céline;
- Vadukul, Devkee M.;
- Papadopoulos, Nicolas;
- Viceconte, Nikenza;
- Claude, Eloïse;
- Vandenberghe, Rik;
- von Arnim, Christine A. F.;
- Constantinescu, Stefan N.;
- Thal, Dietmar Rudolf;
- Decottignies, Anabelle;
- Kienlen-Campard, Pascal
Publication type:
Article
LATE-NC aggravates GVD-mediated necroptosis in Alzheimer's disease.
Published in:
Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01432-6
By:
- Koper, Marta J.;
- Tomé, Sandra O.;
- Gawor, Klara;
- Belet, Annelies;
- Van Schoor, Evelien;
- Schaeverbeke, Jolien;
- Vandenberghe, Rik;
- Vandenbulcke, Mathieu;
- Ghebremedhin, Estifanos;
- Otto, Markus;
- von Arnim, Christine A. F.;
- Balusu, Sriram;
- Blaschko, Matthew B.;
- De Strooper, Bart;
- Thal, Dietmar Rudolf
Publication type:
Article
Biopsy findings of symptomatic cerebral X-linked adrenoleucodystrophy and histological differentiation from multiple sclerosis.
Published in:
Neuropathology & Applied Neurobiology, 2014, v. 40, n. 5, p. 658, doi. 10.1111/nan.12089
By:
- Pfeifenbring, Sabine;
- Baumgarten, Louisa;
- Schüller, Ulrich;
- Rosewich, Hendrik;
- Thal, Dietmar Rudolf;
- Wirtz, Christian Rainer;
- Hecht, Martin;
- Terpolilli, Nicole Angela;
- Brück, Wolfgang
Publication type:
Article
Protein kinase D2 is a novel regulator of glioblastoma growth and tumor formation.
Published in:
Neuro-Oncology, 2011, v. 13, n. 7, p. 710, doi. 10.1093/neuonc/nor084
By:
- Azoitei, Ninel;
- Kleger, Alexander;
- Schoo, Nina;
- Thal, Dietmar Rudolf;
- Brunner, Cornelia;
- Pusapati, Ganesh Varma;
- Filatova, Alina;
- Genze, Felicitas;
- Möller, Peter;
- Acker, Til;
- Kuefer, Rainer;
- Van Lint, Johan;
- Baust, Heinrich;
- Adler, Guido;
- Seufferlein, Thomas
Publication type:
Article
High-molecular weight Aβ oligomers and protofibrils are the predominant Aβ species in the native soluble protein fraction of the AD brain.
Published in:
Journal of Cellular & Molecular Medicine, 2012, v. 16, n. 2, p. 287, doi. 10.1111/j.1582-4934.2011.01306.x
By:
- Upadhaya, Ajeet Rijal;
- Lungrin, Irina;
- Yamaguchi, Haruyasu;
- Fändrich, Marcus;
- Thal, Dietmar Rudolf
Publication type:
Article
Parenchymal and vascular Aβ-deposition and its effects on the degeneration of neurons and cognition in Alzheimer's disease.
Published in:
Journal of Cellular & Molecular Medicine, 2008, v. 12, n. 5b, p. 1848, doi. 10.1111/j.1582-4934.2008.00411.x
By:
- Thal, Dietmar Rudolf;
- Griffin, W. Sue T.;
- Braak, Heiko
Publication type:
Article
Biochemical stages of amyloid-β peptide aggregation and accumulation in the human brain and their association with symptomatic and pathologically preclinical Alzheimer’s disease.
Published in:
Brain: A Journal of Neurology, 2014, v. 137, n. 3, p. 887, doi. 10.1093/brain/awt362
By:
- Rijal Upadhaya, Ajeet;
- Kosterin, Irina;
- Kumar, Sathish;
- von Arnim, Christine A. F.;
- Yamaguchi, Haruyasu;
- Fändrich, Marcus;
- Walter, Jochen;
- Thal, Dietmar Rudolf
Publication type:
Article
Telomere shortening reduces Alzheimer’s disease amyloid pathology in mice.
Published in:
Brain: A Journal of Neurology, 2011, v. 134, n. 7, p. 2044, doi. 10.1093/brain/awr133
By:
- Rolyan, Harshvardhan;
- Scheffold, Annika;
- Heinrich, Annette;
- Begus-Nahrmann, Yvonne;
- Langkopf, Britta Heike;
- Hölter, Sabine M.;
- Vogt-Weisenhorn, Daniela M.;
- Liss, Birgit;
- Wurst, Wolfgang;
- Lie, Dieter Chichung;
- Thal, Dietmar Rudolf;
- Biber, Knut;
- Rudolph, Karl Lenhard
Publication type:
Article
Selective vulnerability of different types of commissural neurons for amyloid β-protein-induced neurodegeneration in APP23 mice correlates with dendritic tree morphology.
Published in:
Brain: A Journal of Neurology, 2006, v. 129, n. 11, p. 2992, doi. 10.1093/brain/awl176
By:
- Estibaliz Capetillo-Zarate;
- Matthias Staufenbiel;
- Dorothee Abramowski;
- Christian Haass;
- Angelika Escher;
- Christine Stadelmann;
- Haruyasu Yamaguchi;
- Otmar D. Wiestler;
- Dietmar Rudolf Thal
Publication type:
Article

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