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Inhibition of an Alzheimer's disease--associated form of necroptosis rescues neuronal death in mouse models.
Published in:
Science Translational Medicine, 2024, v. 16, n. 771, p. 1, doi. 10.1126/scitranslmed.adf5128
By:
- Koper, Marta J.;
- Moonen, Sebastiaan;
- Ronisz, Alicja;
- Ospitalieri, Simona;
- Callaerts-Vegh, Zsuzsanna;
- T'Syen, Dries;
- Rabe, Sabine;
- Staufenbiel, Matthias;
- De Strooper, Bart;
- Balusu, Sriram;
- Thal, Dietmar Rudolf
Publication type:
Article
Posterior Reversible Encephalopathy Syndrome in a Patient With Multiple System Atrophy.
Published in:
Movement Disorders Clinical Practice, 2017, v. 4, n. 5, p. 789, doi. 10.1002/mdc3.12495
By:
- Debray, Sarah;
- Van de Vondel, Saartje;
- Tousseyn, Thomas;
- Thal, Dietmar Rudolf;
- Dewil, Maarten
Publication type:
Article
Correction to: Different aspects of Alzheimer's disease-related amyloid β-peptide pathology and their relationship to amyloid positron emission tomography imaging and dementia.
Published in:
2020
By:
- Thal, Dietmar Rudolf;
- Ronisz, Alicja;
- Tousseyn, Thomas;
- Upadhaya, Ajeet Rijal;
- Balakrishnan, Karthikeyan;
- Vandenberghe, Rik;
- Vandenbulcke, Mathieu;
- von Arnim, Christine A. F.;
- Otto, Markus;
- Beach, Thomas G.;
- Lilja, Johan;
- Heurling, Kerstin;
- Chakrabarty, Aruna;
- Ismail, Azzam;
- Buckley, Christopher;
- Smith, Adrian P. L.;
- Kumar, Sathish;
- Farrar, Gill;
- Walter, Jochen
Publication type:
Correction Notice
Distinct molecular patterns of TDP-43 pathology in Alzheimer's disease: relationship with clinical phenotypes.
Published in:
Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-00934-5
By:
- Tomé, Sandra O.;
- Vandenberghe, Rik;
- Ospitalieri, Simona;
- Van Schoor, Evelien;
- Tousseyn, Thomas;
- Otto, Markus;
- von Arnim, Christine A. F.;
- Thal, Dietmar Rudolf
Publication type:
Article
Sporadic late-onset nemaline myopathy: clinico-pathological characteristics and review of 76 cases.
Published in:
2017
By:
- Schnitzler, Lukas J.;
- Schreckenbach, Tobias;
- Nadaj-Pakleza, Aleksandra;
- Stenzel, Werner;
- Rushing, Elisabeth J.;
- Van Damme, Philip;
- Ferbert, Andreas;
- Petri, Susanne;
- Hartmann, Christian;
- Bornemann, Antje;
- Meisel, Andreas;
- Petersen, Jens A.;
- Tousseyn, Thomas;
- Thal, Dietmar R.;
- Reimann, Jens;
- De Jonghe, Peter;
- Martin, Jean-Jacques;
- Van den Bergh, Peter Y.;
- Schulz, Jörg B.;
- Weis, Joachim
Publication type:
journal article
Clinical and diagnostic implications of Alzheimer's disease copathology in Lewy body disease.
Published in:
Brain: A Journal of Neurology, 2024, v. 147, n. 10, p. 3325, doi. 10.1093/brain/awae203
By:
- Barba, Lorenzo;
- Abu-Rumeileh, Samir;
- Barthel, Henryk;
- Massa, Federico;
- Foschi, Matteo;
- Bellomo, Giovanni;
- Gaetani, Lorenzo;
- Thal, Dietmar R;
- Parnetti, Lucilla;
- Otto, Markus
Publication type:
Article
Seeding, maturation and propagation of amyloid β-peptide aggregates in Alzheimer's disease.
Published in:
2022
By:
- Li, Xiaohang;
- Ospitalieri, Simona;
- Robberechts, Tessa;
- Hofmann, Linda;
- Schmid, Christina;
- Upadhaya, Ajeet Rijal;
- Koper, Marta J;
- Arnim, Christine A F von;
- Kumar, Sathish;
- Willem, Michael;
- Gnoth, Kathrin;
- Ramakers, Meine;
- Schymkowitz, Joost;
- Rousseau, Frederic;
- Walter, Jochen;
- Ronisz, Alicja;
- Balakrishnan, Karthikeyan;
- Thal, Dietmar Rudolf;
- Rijal Upadhaya, Ajeet;
- von Arnim, Christine A F
Publication type:
journal article
Co-pathologies in Alzheimer's disease: just multiple pathologies or partners in crime?
Published in:
2021
By:
- Tomé, Sandra O;
- Thal, Dietmar Rudolf
Publication type:
journal article
Monitoring the progression of Alzheimer's disease with τ-PET.
Published in:
2016
By:
- Thal, Dietmar Rudolf;
- Vandenberghe, Rik
Publication type:
journal article
Retina pathology as a target for biomarkers for Alzheimer's disease: Current status, ophthalmopathological background, challenges, and future directions.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 1, p. 728, doi. 10.1002/alz.13529
By:
- Alber, Jessica;
- Bouwman, Femke;
- den Haan, Jurre;
- Rissman, Robert A.;
- De Groef, Lies;
- Koronyo‐Hamaoui, Maya;
- Lengyel, Imre;
- Thal, Dietmar Rudolf
Publication type:
Article
Primary retinal tauopathy: A tauopathy with a distinct molecular pattern.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 1, p. 330, doi. 10.1002/alz.13424
By:
- Walkiewicz, Grzegorz;
- Ronisz, Alicja;
- Van Ginderdeuren, Rita;
- Lemmens, Sophie;
- Bouwman, Femke H.;
- Hoozemans, Jeroen J. M.;
- Morrema, Tjado H. J.;
- Rozemuller, Annemieke J.;
- Hart de Ruyter, Frederique J.;
- De Groef, Lies;
- Stalmans, Ingeborg;
- Thal, Dietmar Rudolf
Publication type:
Article
Ponatinib and dabrafenib reduce the accumulation of necroptosis‐related proteins and neuronal loss in APP23xTAU58 mice.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.077757
By:
- Koper, Marta J;
- Moonen, Sebastiaan;
- Ronisz, Alicja;
- Ospitalieri, Simona;
- Rabe, Sabine;
- Staufenbiel, Matthias;
- De Strooper, Bart;
- Balusu, Sriram;
- Thal, Dietmar Rudolf
Publication type:
Article
A retinal tauopathy with a characteristic molecular pattern points to the existence of a "Primary retinal tauopathy".
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076166
By:
- Walkiewicz, Grzegorz;
- Ronisz, Alicja;
- Van Ginderdeuren, Rita;
- Lemmens, Sophie;
- Bouwman, Femke H.;
- Hoozemans, Jeroen;
- Morrema, Tjado;
- Rozemuller, Annemieke J.M.;
- de Ruyter, Frederique J. Hart;
- De Groef, Lies;
- Stalmans, Ingeborg;
- Thal, Dietmar Rudolf
Publication type:
Article
Single nucleotide polymorphisms linked to Alzheimer's disease are associated with distinct neuropathological phenotypes.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078165
By:
- Laureyssen, Celeste;
- Gawor, Klara;
- Van Dongen, Jasper;
- Kucukali, Fahri;
- Koper, Marta J;
- Ronisz, Alicja;
- Otto, Markus;
- von Arnim, Christine;
- Van Damme, Philip;
- Vandenberghe, Rik;
- Thal, Dietmar Rudolf;
- Sleegers, Kristel
Publication type:
Article
Association of hippocampal neuron loss, pTDP‐43, and Alzheimer's disease pathology with the presence of cerebral Lewy bodies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077833
By:
- Gawor, Klara;
- Tomé, Sandra O.;
- Ronisz, Alicja;
- Ospitalieri, Simona;
- Vandenberghe, Rik;
- von Arnim, Christina;
- Otto, Markus;
- Thal, Dietmar Rudolf
Publication type:
Article
The impact of co‐morbid LATE‐NC pathology in Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.073996
By:
- Tomé, Sandra O.;
- Tsaka, Grigoria;
- Ronisz, Alicja;
- Ospitalieri, Simona;
- Gawor, Klara;
- von Arnim, Christina;
- Otto, Markus;
- Vandenberghe, Rik;
- Schymkowitz, Joost;
- Rousseau, Frederic;
- Thal, Dietmar Rudolf
Publication type:
Article
Single nucleotide polymorphisms linked to Alzheimer's disease are associated with distinct neuropathological phenotypes.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078165
By:
- Laureyssen, Celeste;
- Gawor, Klara;
- Van Dongen, Jasper;
- Kucukali, Fahri;
- Koper, Marta J;
- Ronisz, Alicja;
- Otto, Markus;
- von Arnim, Christine;
- Van Damme, Philip;
- Vandenberghe, Rik;
- Thal, Dietmar Rudolf;
- Sleegers, Kristel
Publication type:
Article
Association of hippocampal neuron loss, pTDP‐43, and Alzheimer's disease pathology with the presence of cerebral Lewy bodies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077833
By:
- Gawor, Klara;
- Tomé, Sandra O.;
- Ronisz, Alicja;
- Ospitalieri, Simona;
- Vandenberghe, Rik;
- von Arnim, Christina;
- Otto, Markus;
- Thal, Dietmar Rudolf
Publication type:
Article
The impact of co‐morbid LATE‐NC pathology in Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.073996
By:
- Tomé, Sandra O.;
- Tsaka, Grigoria;
- Ronisz, Alicja;
- Ospitalieri, Simona;
- Gawor, Klara;
- von Arnim, Christina;
- Otto, Markus;
- Vandenberghe, Rik;
- Schymkowitz, Joost;
- Rousseau, Frederic;
- Thal, Dietmar Rudolf
Publication type:
Article
Stages of retinal tauopathy and its relation to age and non‐AD retinal pathologies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.064086
By:
- Thal, Dietmar Rudolf;
- Ronisz, Alicja;
- Van Ginderdeuren, Rita;
- Lemmens, Sophie;
- Stalmans, Ingeborg;
- De Groef, Lies;
- Walkiewicz, Grzegorz
Publication type:
Article
Neuronal loss of the nucleus basalis of Meynert in primary progressive aphasia is associated with Alzheimer's disease neuropathological changes.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 4, p. 1440, doi. 10.1002/alz.12794
By:
- Schaeverbeke, Jolien;
- Tomé, Sandra O.;
- Ronisz, Alicja;
- Ospitalieri, Simona;
- von Arnim, Christine A. F.;
- Otto, Markus;
- Vandenberghe, Rik;
- Thal, Dietmar Rudolf
Publication type:
Article
Astrocytes mediate neuronal network hyperactivity in early AD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.068629
By:
- Shah, Disha;
- Gsell, Willy;
- Wahis, Jérôme;
- Luckett, Emma S.;
- Jamoulle, Tarik;
- Preman, Pranav;
- Moechars, Daan;
- Craessaerts, Katleen;
- Horré, Katrien;
- Hendrickx, Véronique;
- Jaspers, Tom;
- Wolfs, Leen;
- Vermaercke, Ben;
- Fiers, Mark;
- Holt, Matthew;
- Vegh, Zsuzsanna;
- Thal, Dietmar Rudolf;
- D'Hooge, Rudi;
- Vandenberghe, Rik;
- Himmelreich, Uwe
Publication type:
Article
Sequence of proteome profiles in preclinical and symptomatic Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 6, p. 946, doi. 10.1002/alz.12345
By:
- Li, Xiaohang;
- Tsolis, Konstantinos C.;
- Koper, Marta J.;
- Ronisz, Alicja;
- Ospitalieri, Simona;
- von Arnim, Christine A.F.;
- Vandenberghe, Rik;
- Tousseyn, Thomas;
- Scheuerle, Angelika;
- Economou, Anastassios;
- Carpentier, Sebastien;
- Otto, Markus;
- Thal, Dietmar Rudolf
Publication type:
Article
Hierarchical involvement of molecular players in human neocortex in the course of preclinical and symptomatic Alzheimer's disease: Developing topics.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.047351
By:
- Li, Xiaohang;
- Tsolis, Konstantinos C;
- Koper, Marta J;
- Ronisz, Alicja;
- Ospitalieri, Simona;
- von Arnim, Christine;
- Otto, Markus;
- Vandenberghe, Rik;
- Tousseyn, Thomas;
- Scheuerle, Angelika;
- Economou, Tassos;
- Carpentier, Sebastien;
- Thal, Dietmar Rudolf
Publication type:
Article
Classification of 18F‐flutemetamol scans using machine learning with neuropathology as standard of truth: Neuroimaging / Optimal neuroimaging measures for tracking disease progression.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044550
By:
- Reinartz, Mariska;
- Farrar, Gill;
- Buckley, Christopher;
- Smith, Adrian;
- Thal, Dietmar Rudolf;
- Dupont, Patrick;
- Vandenberghe, Rik
Publication type:
Article
Two distinct molecular patterns of TDP‐43 pathology in cases with Alzheimer's disease pathology: Human neuropathology/proteinopathies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043074
By:
- Tomé, Sandra;
- Vandenberghe, Rik;
- Ospitalieri, Simona;
- Van Schoor, Evelien;
- Tousseyn, Thomas;
- Otto, Markus;
- von Arnim, Christine;
- Thal, Dietmar Rudolf
Publication type:
Article
Chimeric models to analyze human neuron and astroglia responses in Alzheimer's disease: Molecular and cell biology/stem cells, iPS cells.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042678
By:
- Arranz, Amaia M.;
- Preman, Pranav;
- T.C.W., Julia;
- Snellinx, An;
- Calafate, Sara;
- Thal, Dietmar Rudolf;
- Goate, Alison M.;
- De Strooper, Bart
Publication type:
Article
Alzheimer's disease‐related necroptotic pathology: An exclusive presence of the necrosome in granulovacuolar degeneration inclusions in human and transgenic mouse brains: Molecular and cell biology/neuronal cell death mechanisms (i.e. apoptosis).
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042460
By:
- Koper, Marta J.;
- Van Schoor, Evelien;
- Ospitalieri, Simona;
- Vandenberghe, Rik;
- Vandenbulcke, Mathieu;
- von Arnim, Christine;
- Tousseyn, Thomas;
- Reichwald, Julia;
- Rabe, Sabine;
- Staufenbiel, Matthias;
- Balusu, Sriram;
- De Strooper, Bart;
- Thal, Dietmar Rudolf
Publication type:
Article
Impact of the presence of AβN3pE and AβpSer8 in Aβ aggregates on the induction of Aβ seeding and spreading in the brains of APP23 mice: Human neuropathology/amyloid.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.038224
By:
- Robberechts, Tessa;
- Ronisz, Alicja;
- Ospitalieri, Simona;
- Koper, Marta J.;
- Kumar, Sathish;
- Walter, Jochen;
- Willem, Michael;
- Li, Xiaohang;
- Thal, Dietmar Rudolf
Publication type:
Article
P3‐404: STRIATAL AMYLOID VIA [18F]FLUTEMETAMOL PREDICTS CONVERSION FROM AMCI TO PAD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1108, doi. 10.1016/j.jalz.2019.06.3438
By:
- Pillay, Lovena Chedumbarum;
- Buckley, Chris J.;
- Smith, Adrian;
- Battle, Mark R.;
- Jenkinson, Mark;
- Beach, Thomas G.;
- Thal, Dietmar;
- Wolk, David A.
Publication type:
Article
P2‐350: POSTMORTEM BINDING STUDY OF [18F]‐AV1451 AND [18F]‐THK5351 IN SEMANTIC VARIANT PRIMARY PROGRESSIVE APHASIA.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P729, doi. 10.1016/j.jalz.2019.06.2757
By:
- Schaeverbeke, Jolien;
- Celen, Sofie;
- Ronisz, Alicja;
- Serdons, Kim;
- Thal, Dietmar;
- Bormans, Guy;
- Vandenberghe, Rik
Publication type:
Article
Abnormal Paraplegin Expression in Swollen Neurites, τ- and α-Synuclein Pathology in a Case of Hereditary Spastic Paraplegia SPG7 with an Ala510Val Mutation.
Published in:
International Journal of Molecular Sciences, 2015, v. 16, n. 10, p. 25050, doi. 10.3390/ijms161025050
By:
- Thal, Dietmar R.;
- Züchner, Stephan;
- Gierer, Stephan;
- Schulte, Claudia;
- Schöls, Ludger;
- Schüle, Rebecca;
- Synofzik, Matthis
Publication type:
Article
The role of PTB domain containing adaptor proteins on PICALM-mediated APP endocytosis and localization.
Published in:
Biochemical Journal, 2019, v. 476, n. 14, p. 2093, doi. 10.1042/BCJ20180840
By:
- Merthan, Lisa;
- Haller, Amelie;
- Thal, Dietmar R.;
- von Einem, Bjoern;
- von Arnim, Christine A. F.
Publication type:
Article
Mapping the sequence specificity of heterotypic amyloid interactions enables the identification of aggregation modifiers.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28955-9
By:
- Louros, Nikolaos;
- Ramakers, Meine;
- Michiels, Emiel;
- Konstantoulea, Katerina;
- Morelli, Chiara;
- Garcia, Teresa;
- Moonen, Nele;
- D'Haeyer, Sam;
- Goossens, Vera;
- Thal, Dietmar Rudolf;
- Audenaert, Dominique;
- Rousseau, Frederic;
- Schymkowitz, Joost
Publication type:
Article
Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21972-0
By:
- Wettstein, Lukas;
- Weil, Tatjana;
- Conzelmann, Carina;
- Müller, Janis A.;
- Groß, Rüdiger;
- Hirschenberger, Maximilian;
- Seidel, Alina;
- Klute, Susanne;
- Zech, Fabian;
- Prelli Bozzo, Caterina;
- Preising, Nico;
- Fois, Giorgio;
- Lochbaum, Robin;
- Knaff, Philip Maximilian;
- Mailänder, Volker;
- Ständker, Ludger;
- Thal, Dietmar Rudolf;
- Schumann, Christian;
- Stenger, Steffen;
- Kleger, Alexander
Publication type:
Article
Clearance of amyloid β-protein and its role in the spreading of Alzheimer's disease pathology.
Published in:
Frontiers in Aging Neuroscience, 2015, v. 7, p. 1, doi. 10.3389/fnagi.2015.00025
By:
- Thal, Dietmar R.
Publication type:
Article
PERFORMANCE OF [18F]FLUTEMETAMOL AMYLOID IMAGING AGAINST THE CURRENT (2012) NIA-AA RECOMMENDATIONS FOR THE NEUROPATHOLOGICAL DIAGNOSIS OF ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P926, doi. 10.1016/j.jalz.2016.06.1916
By:
- Ikonomovic, Milos D.;
- Salloway, Stephen;
- Thal, Dietmar R.;
- Sherwin, Paul;
- Farrar, Gill;
- Zanette, Michelle;
- Buckley, Chris J.;
- Smith, Adrian
Publication type:
Article
[18F]flutemetamol amyloid positron emission tomography in preclinical and symptomatic Alzheimer's disease: Specific detection of advanced phases of amyloid-β pathology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 8, p. 975, doi. 10.1016/j.jalz.2015.05.018
By:
- Thal, Dietmar Rudolf;
- Beach, Thomas G.;
- Zanette, Michelle;
- Heurling, Kerstin;
- Chakrabarty, Aruna;
- Ismail, Azzam;
- Smith, Adrian P.L.;
- Buckley, Christopher
Publication type:
Article
Role of free and exosomal tdp-43 as a diagnostic tool in neurodegenerative diseases.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2014, v. 10, p. P147, doi. 10.1016/j.jalz.2014.04.107
By:
- Feneberg, Emily;
- Otto, Markus;
- Steinacker, Petra;
- Lehnert, Stefan;
- Schneider, Anja;
- Linsenmeier, Miriam;
- Walther, Paul;
- Thal, Dietmar Rudolf;
- Ludolph, Albert
Publication type:
Article
National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2012, v. 8, n. 1, p. 1, doi. 10.1016/j.jalz.2011.10.007
By:
- Hyman, Bradley T.;
- Phelps, Creighton H.;
- Beach, Thomas G.;
- Bigio, Eileen H.;
- Cairns, Nigel J.;
- Carrillo, Maria C.;
- Dickson, Dennis W.;
- Duyckaerts, Charles;
- Frosch, Matthew P.;
- Masliah, Eliezer;
- Mirra, Suzanne S.;
- Nelson, Peter T.;
- Schneider, Julie A.;
- Thal, Dietmar Rudolf;
- Thies, Bill;
- Trojanowski, John Q.;
- Vinters, Harry V.;
- Montine, Thomas J.
Publication type:
Article
Elevated levels of soluble, high molecular weight SDS-denaturable Aβ-aggregates are associated with dendritic degeneration in APP-transgenic mouse models
Published in:
2011
By:
- Upadhaya, Ajeet Rijal;
- Capetillo-Zarate, Estibaliz;
- Lungrin, Irina;
- Abramowski, Dorothee;
- Kumar, Sathish;
- Yamaguchi, Haruyasu;
- Haass, Christian;
- Walter, Jochen;
- Staufenbiel, Matthias;
- Fändrich, Marcus;
- Thal, Dietmar
Publication type:
Abstract
tau pathology in Young people and its progression Before Abeta Deposition
Published in:
2011
By:
- Thal, Dietmar;
- Upadhaya, Ajeet Rijal;
- Fändrich, Marcus;
- Del Tredici, Kelly;
- Braak, Heiko
Publication type:
Abstract
Stages of granulovacuolar degeneration and its relation to Alzheimer's disease
Published in:
2011
By:
- Thal, Dietmar;
- Braak, Heiko;
- Del Tredici, Kelly;
- Knippschild, Uwe
Publication type:
Abstract
Chitinase Enzyme Activity in Cerebral Spinal Fluid is Strongly Associated with Alzheimer’s Disease
Published in:
2011
By:
- von Arnim, Christine;
- Watabe-Rudolph, Masami;
- Song, Zhangfa;
- Schnack, Cathrin;
- Begus-Nahrmann, Yvonne;
- Rolyan, Harshvardhan;
- Otto, Markus;
- Tumani, Hayrettin;
- Thal, Dietmar;
- Attems, Johannes;
- Jellinger, Kurt;
- Kestler, Hans;
- Rudolph, Karl
Publication type:
Abstract
Site-Specific Effect of Amyloid B-Peptide (Aβ) Phosphorylation on Its Conformation and Aggregation
Published in:
2011
By:
- Kumar, Sathish;
- Rezaei-Ghaleh, Nasrollah;
- Zweckstetter, Markus;
- Terwel, Dick;
- Thal, Dietmar;
- Heneka, Michael;
- Walter, Jochen
Publication type:
Abstract
Genetic variants in presenilins and correlation to amyloid-beta 42 levels in cerebrospinal fluid and diagnosis of Alzheimer's disease
Published in:
2009
By:
- von Arnim, Christine A.F.;
- Lebedeva, Elena;
- Thal, Dietmar;
- Ghebremedhin, Estifanos;
- Strauss, Joachim;
- Özer, Esra;
- von Einem, Björn;
- Tumani, Hayrettin;
- Otto, Markus;
- Riepe, Matthias W.;
- Ludolph, Albert C.;
- Kirchheiner, Julia
Publication type:
Abstract
Phenotypic and genetic subclassification of Alzheimer's disease
Published in:
2009
By:
- Thal, Dietmar R.;
- Koelsch, Heike;
- Papassotiropoulos, Andreas;
- Saido, Takaomi C.;
- Griffin, Sue T.;
- van Dooren, Tom;
- van Leuven, Fred;
- Ghebremedhin, Estifanos
Publication type:
Abstract
P4-295: Small vessel disease–induced microvascular protein leakage provides a possible pathogenetic link to Alzheimer's disease
Published in:
2008
By:
- Thal, Dietmar R.;
- Tamboli, Irfan Y.;
- Walter, Jochen;
- Birkenmeier, Gerd;
- Pietrzik, Claus U.;
- Utter, Sabrina
Publication type:
Abstract
P4-190: Role of gamma-secretase in lipoprotein endocytosis
Published in:
2008
By:
- Walter, Jochen;
- Thelen, Karin;
- Lütjohann, Dieter;
- DeWachter, Ilse;
- van Leuven, Fred;
- Sisodia, Sangram S.;
- St. George-Hyslop, Peter;
- Thal, Dietmar;
- Tamboli, Irfan
Publication type:
Abstract
P3-274: Major genetic risk factors for age-related macular degeneration are not associated with Alzheimer's disease
Published in:
2008
By:
- Wollmer, M. Axel;
- Maruszak, Aleksandra;
- Tsolaki, Magdalini;
- Kapaki, Elisabeth;
- Thal, Dietmar R.;
- Michikawa, Makoto;
- Barcikowska, Maria;
- Zekanowski, Cezary
Publication type:
Abstract

Found: 166