Works by Teschendorff, Andrew E.

Results: 92

Epigenetic clocks and inflammaging: pitfalls caused by ignoring cell-type heterogeneity.

Published in:

GeroScience, 2025, v. 47, n. 3, p. 2707, doi. 10.1007/s11357-025-01677-8

By:

Guo, Xiaolong;
Teschendorff, Andrew E.

Publication type:

Article

Tumor origin detection with tissue-specific miRNA and DNA methylation markers.

Published in:

Bioinformatics, 2018, v. 34, n. 3, p. 398, doi. 10.1093/bioinformatics/btx622

By:

Tang, Wei;
Wan, Shixiang;
Yang, Zhen;
Teschendorff, Andrew E;
Zou, Quan

Publication type:

Article

ChAMP: updated methylation analysis pipeline for Illumina BeadChips.

Published in:

Bioinformatics, 2017, v. 33, n. 24, p. 3982, doi. 10.1093/bioinformatics/btx513

By:

Yuan Tian;
Morris, Tiffany J.;
Webster, Amy P.;
Zhen Yang;
Beck, Stephan;
Feber, Andrew;
Teschendorff, Andrew E.

Publication type:

Article

A systems-level integrative framework for genome-wide DNA methylation and gene expression data identifies differential gene expression modules under epigenetic control.

Published in:

Bioinformatics, 2014, v. 30, n. 16, p. 2360, doi. 10.1093/bioinformatics/btu316

By:

Jiao, Yinming;
Widschwendter, Martin;
Teschendorff, Andrew E.

Publication type:

Article

ChAMP: 450k Chip Analysis Methylation Pipeline.

Published in:

Bioinformatics, 2014, v. 30, n. 3, p. 428, doi. 10.1093/bioinformatics/btt684

By:

Morris, Tiffany J.;
Butcher, Lee M.;
Feber, Andrew;
Teschendorff, Andrew E.;
Chakravarthy, Ankur R.;
Wojdacz, Tomasz K.;
Beck, Stephan

Publication type:

Article

A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data.

Published in:

Bioinformatics, 2013, v. 29, n. 2, p. 189, doi. 10.1093/bioinformatics/bts680

By:

Teschendorff, Andrew E.;
Marabita, Francesco;
Lechner, Matthias;
Bartlett, Thomas;
Tegner, Jesper;
Gomez-Cabrero, David;
Beck, Stephan

Publication type:

Article

Differential variability improves the identification of cancer risk markers in DNA methylation studies profiling precursor cancer lesions.

Published in:

Bioinformatics, 2012, v. 28, n. 11, p. 1487, doi. 10.1093/bioinformatics/bts170

By:

Teschendorff, Andrew E.;
Widschwendter, Martin

Publication type:

Article

Independent surrogate variable analysis to deconvolve confounding factors in large-scale microarray profiling studies.

Published in:

Bioinformatics, 2011, v. 27, n. 11, p. 1496, doi. 10.1093/bioinformatics/btr171

By:

Teschendorff, Andrew E.;
Zhuang, Joanna;
Widschwendter, Martin

Publication type:

Article

PACK: Profile Analysis using Clustering and Kurtosis to find molecular classifiers in cancer.

Published in:

Bioinformatics, 2006, v. 22, n. 18, p. 2269, doi. 10.1093/bioinformatics/btl174

By:

Andrew E. Teschendorff;
Ali Naderi;
Nuno L. Barbosa-Morais;
Carlos Caldas

Publication type:

Article

Longitudinal analysis of epigenome-wide DNA methylation reveals novel loci associated with BMI change in East Asians.

Published in:

Clinical Epigenetics, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13148-024-01679-x

By:

Li, Wenran;
Xia, Mingfeng;
Zeng, Hailuan;
Lin, Huandong;
Teschendorff, Andrew E.;
Gao, Xin;
Wang, Sijia

Publication type:

Article

EPISCORE: cell type deconvolution of bulk tissue DNA methylomes from single-cell RNA-Seq data.

Published in:

Genome Biology, 2020, v. 21, n. 1, p. N.PAG, doi. 10.1186/s13059-020-02126-9

By:

Teschendorff, Andrew E.;
Zhu, Tianyu;
Breeze, Charles E.;
Beck, Stephan

Publication type:

Article

Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus.

Published in:

BMC Medical Genomics, 2010, v. 3, p. 33, doi. 10.1186/1755-8794-3-33

By:

Bell, Christopher G.;
Teschendorff, Andrew E.;
Rakyan, Vardhman K.;
Maxwell, Alexander P.;
Beck, Stephan;
Savage, David A.

Publication type:

Article

ESR1 gene amplification in breast cancer: a common phenomenon?

Published in:

2008

By:

Brown, Lindsay A.;
Hoog, Jeremy;
Suet-Feung Chin;
Yu Tao;
Zayed, Abd Alnaser;
Koei Chin;
Teschendorff, Andrew E.;
Quackenbush, John F.;
Marioni, John C.;
Leung, Samuel;
Perou, Charles M.;
Neilsen, Torsten O.;
Ellis, Matthew;
Gray, Joe W.;
Bernard, Philip S.;
Huntsman, David G.;
Caldas, Carlos

Publication type:

Letter

Improved prognostic classification of breast cancer defined by antagonistic activation patterns of immune response pathway modules.

Published in:

BMC Cancer, 2010, v. 10, p. 604, doi. 10.1186/1471-2407-10-604

By:

Teschendorff, Andrew E.;
Gomez, Sergio;
Arenas, Alex;
El-Ashry, Dorraya;
Schmidt, Marcus;
Gehrmann, Mathias;
Caldas, Carlos

Publication type:

Article

Co-amplification of 8p12 and 11q13 in breast cancers is not the result of a single genomic event.

Published in:

Genes, Chromosomes & Cancer, 2007, v. 46, n. 5, p. 427, doi. 10.1002/gcc.20424

By:

Paterson, Anna L.;
Pole, Jessica C. M.;
Blood, Katherine A.;
Garcia, Maria J.;
Cooke, Susanna L.;
Teschendorff, Andrew E.;
Wang, Yanzhong;
Chin, Suet-Feung;
Ylstra, Bauke;
Caldas, Carlos;
Edwards, Paul A. W.

Publication type:

Article

A variational Bayesian mixture modelling framework for cluster analysis of gene-expression data.

Published in:

Bioinformatics, 2005, v. 21, n. 13, p. 3025

By:

Andrew E. Teschendorff

Publication type:

Article

Single-cell landscape in mammary epithelium reveals bipotent-like cells associated with breast cancer risk and outcome.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0554-8

By:

Chen, Weiyan;
Morabito, Samuel J.;
Kessenbrock, Kai;
Enver, Tariq;
Meyer, Kerstin B.;
Teschendorff, Andrew E.

Publication type:

Article

Tissue-independent and tissue-specific patterns of DNA methylation alteration in cancer.

Published in:

Epigenetics & Chromatin, 2016, v. 9, p. 1, doi. 10.1186/s13072-016-0058-4

By:

Yuting Chen;
Breeze, Charles E.;
Shao Zhen;
Beck, Stephan;
Teschendorff, Andrew E.

Publication type:

Article

JAK2-Centered Interactome Hotspot Identified by an Integrative Network Algorithm in Acute Stanford Type A Aortic Dissection.

Published in:

PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0089406

By:

Pan, Sun;
Wu, Duojiao;
Teschendorff, Andrew E.;
Hong, Tao;
Wang, Linyan;
Qian, Mengjia;
Wang, Chunsheng;
Wang, Xiangdong

Publication type:

Article

Corruption of the Intra-Gene DNA Methylation Architecture Is a Hallmark of Cancer.

Published in:

PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0068285

By:

Bartlett, Thomas E.;
Zaikin, Alexey;
Olhede, Sofia C.;
West, James;
Teschendorff, Andrew E.;
Widschwendter, Martin

Publication type:

Article

Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus.

Published in:

PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0014040

By:

Bell, Christopher G.;
Finer, Sarah;
Lindgren, Cecilia M.;
Wilson, Gareth A.;
Rakyan, Vardhman K.;
Teschendorff, Andrew E.;
Akan, Pelin;
Stupka, Elia;
Down, Thomas A.;
Prokopenko, Inga;
Morison, Ian M.;
Mill, Jonathan;
Pidsley, Ruth;
Deloukas, Panos;
Frayling, Timothy M.;
Hattersley, Andrew T.;
McCarthy, Mark I.;
Beck, Stephan;
Hitman, Graham A.

Publication type:

Article

An Epigenetic Signature in Peripheral Blood Predicts Active Ovarian Cancer.

Published in:

PLoS ONE, 2009, v. 4, n. 12, p. 1, doi. 10.1371/journal.pone.0008274

By:

Teschendorff, Andrew E.;
Menon, Usha;
Gentry-Maharaj, Aleksandra;
Ramus, Susan J.;
Gayther, Simon A.;
Apostolidou, Sophia;
Jones, Allison;
Lechner, Matthias;
Beck, Stephan;
Jacobs, Ian J.;
Widschwendter, Martin

Publication type:

Article

FastQTLmapping: an ultra-fast and memory efficient package for mQTL-like analysis.

Published in:

BMC Bioinformatics, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12859-025-06130-3

By:

Gao, Xingjian;
Li, Jiarui;
Liu, Xinxuan;
Peng, Qianqian;
Jing, Han;
Hadi, Sibte;
Teschendorff, Andrew E.;
Wang, Sijia;
Liu, Fan

Publication type:

Article

Role of DNA methylation and epigenetic silencing of HAND2 in endometrial cancer development.

Published in:

2013

By:

Jones, Allison;
Teschendorff, Andrew E;
Li, Quanxi;
Hayward, Jane D;
Kannan, Athilakshmi;
Mould, Tim;
West, James;
Zikan, Michal;
Cibula, David;
Fiegl, Heidi;
Lee, Shih-Han;
Wik, Elisabeth;
Hadwin, Richard;
Arora, Rupali;
Lemech, Charlotte;
Turunen, Henna;
Pakarinen, Päivi;
Jacobs, Ian J;
Salvesen, Helga B;
Bagchi, Milan K

Publication type:

journal article

Role of DNA Methylation and Epigenetic Silencing of <i>HAND2</i> in Endometrial Cancer Development.

Published in:

PLoS Medicine, 2013, v. 10, n. 11, p. 1, doi. 10.1371/journal.pmed.1001551

By:

Jones, Allison;
Teschendorff, Andrew E.;
Li, Quanxi;
Hayward, Jane D.;
Kannan, Athilakshmi;
Mould, Tim;
West, James;
Zikan, Michal;
Cibula, David;
Fiegl, Heidi;
Lee, Shih-Han;
Wik, Elisabeth;
Hadwin, Richard;
Arora, Rupali;
Lemech, Charlotte;
Turunen, Henna;
Pakarinen, Päivi;
Jacobs, Ian J.;
Salvesen, Helga B.;
Bagchi, Milan K.

Publication type:

Article

Universal penalized regression (Elastic-net) model with differentially methylated promoters for oral cancer prediction.

Published in:

European Journal of Medical Research, 2024, v. 29, n. 1, p. 1, doi. 10.1186/s40001-024-02047-4

By:

Das, Shantanab;
Karuri, Saikat;
Chakraborty, Joyeeta;
Basu, Baidehi;
Chandra, Aditi;
Aravindan, S.;
Chakraborty, Anirvan;
Paul, Debashis;
Ray, Jay Gopal;
Lechner, Matt;
Beck, Stephan;
Teschendorff, E. Andrew;
Chatterjee, Raghunath

Publication type:

Article

Psychosocial adversity and socioeconomic position during childhood and epigenetic age: analysis of two prospective cohort studies.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 7, p. 1301, doi. 10.1093/hmg/ddy036

By:

Lawn, Rebecca B.;
Anderson, Emma L.;
Suderman, Matthew;
Simpkin, Andrew J.;
Gaunt, Tom R.;
Teschendorff, Andrew E.;
Widschwendter, Martin;
Hardy, Rebecca;
Kuh, Diana;
Relton, Caroline L.;
Howe, Laura D.

Publication type:

Article

Age-associated epigenetic drift: implications, and a case of epigenetic thrift?

Published in:

Human Molecular Genetics, 2013, v. 22, n. R1, p. R7, doi. 10.1093/hmg/ddt375

By:

Teschendorff, Andrew E.;
West, James;
Beck, Stephan

Publication type:

Article

Cell-attribute aware community detection improves differential abundance testing from single-cell RNA-Seq data.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39017-z

By:

Maity, Alok K.;
Teschendorff, Andrew E.

Publication type:

Article

A comparison of epigenetic mitotic-like clocks for cancer risk prediction.

Published in:

Genome Medicine, 2020, v. 12, n. 1, p. 1, doi. 10.1186/s13073-020-00752-3

By:

Teschendorff, Andrew E.

Publication type:

Article

Stochastic epigenetic outliers can define field defects in cancer.

Published in:

BMC Bioinformatics, 2016, v. 17, p. 1, doi. 10.1186/s12859-016-1056-z

By:

Teschendorff, Andrew E.;
Jones, Allison;
Widschwendter, Martin

Publication type:

Article

Elucidating the Altered Transcriptional Programs in Breast Cancer using Independent Component Analysis.

Published in:

PLoS Computational Biology, 2007, v. 3, n. 8, p. 1539, doi. 10.1371/journal.pcbi.0030161

By:

Teschendorff, Andrew E.;
Journée, Michel;
Absil, Pierre A.;
Sepulchre, Rodolphe;
Caldas, Carlos

Publication type:

Article

Integrative analysis of genomic and epigenomic regulation reveals miRNA mediated tumor heterogeneity and immune evasion in lower grade glioma.

Published in:

Communications Biology, 2024, v. 7, n. 7, p. 1, doi. 10.1038/s42003-024-06488-9

By:

Yang, Zhen;
Liu, Xiaocen;
Xu, Hao;
Teschendorff, Andrew E.;
Xu, Lingjie;
Li, Jingyi;
Fu, Minjie;
Liu, Jun;
Zhou, Hanyu;
Wang, Yingying;
Zhang, Licheng;
He, Yungang;
Lv, Kun;
Yang, Hui

Publication type:

Article

Increased signaling entropy in cancer requires the scale-free property of protein interaction networks.

Published in:

Scientific Reports, 2015, p. 9646, doi. 10.1038/srep09646

By:

Teschendorff, Andrew E.;
Banerji, Christopher R. S.;
Severini, Simone;
Kuehn, Reimer;
Sollich, Peter

Publication type:

Article

Roadmap for investigating epigenome deregulation and environmental origins of cancer.

Published in:

International Journal of Cancer, 2018, v. 142, n. 5, p. 874, doi. 10.1002/ijc.31014

By:

Herceg, Zdenko;
Ghantous, Akram;
Wild, Christopher P.;
Sklias, Athena;
Casati, Lavinia;
Duthie, Susan J.;
Fry, Rebecca;
Issa, Jean‐Pierre;
Kellermayer, Richard;
Koturbash, Igor;
Kondo, Yukata;
Lepeule, Johanna;
Lima, Sheila C. S.;
Marsit, Carmen J.;
Rakyan, Vardhman;
Saffery, Richard;
Taylor, Jack A.;
Teschendorff, Andrew E.;
Ushijima, Toshikazu;
Vineis, Paolo

Publication type:

Article

Common germline polymorphisms in COMT, CYP19A1, ESR1, PGR, SULT1E1 and STS and survival after a diagnosis of breast cancer.

Published in:

International Journal of Cancer, 2009, v. 125, n. 11, p. 2687, doi. 10.1002/ijc.24678

By:

Udler, Miriam S.;
Azzato, Elizabeth M.;
Healey, Catherine S.;
Ahmed, Shahana;
Pooley, Karen A.;
Greenberg, David;
Shah, Mitul;
Teschendorff, Andrew E.;
Caldas, Carlos;
Dunning, Alison M.;
Ostrander, Elaine A.;
Caporaso, Neil E.;
Easton, Douglas;
Pharoah, Paul D.

Publication type:

Article

Increased entropy of signal transduction in the cancer metastasis phenotype.

Published in:

BMC Systems Biology, 2010, v. 4, p. 104, doi. 10.1186/1752-0509-4-104

By:

Teschendorff, Andrew E.;
Severini, Simone

Publication type:

Article

Allele-Specific Up-Regulation of FGFR2 Increases Susceptibility to Breast Cancer.

Published in:

PLoS Biology, 2008, v. 6, n. 5, p. e108, doi. 10.1371/journal.pbio.0060108

By:

Meyer, Kerstin B.;
Maia, Ana-Teresa;
O'Reilly, Martin;
Teschendorff, Andrew E.;
Suet-Feung Chin;
Caldas, Carlos;
Ponder, Bruce A. J.

Publication type:

Article

Improved detection of tumor suppressor events in single-cell RNA-Seq data.

Published in:

NPJ Genomic Medicine, 2020, v. 5, n. 1, p. N.PAG, doi. 10.1038/s41525-020-00151-y

By:

Teschendorff, Andrew E.;
Wang, Ning

Publication type:

Article

Quantifying Waddington's epigenetic landscape: a comparison of single-cell potency measures.

Published in:

Briefings in Bioinformatics, 2020, v. 21, n. 1, p. 248, doi. 10.1093/bib/bby093

By:

Shi, Jifan;
Teschendorff, Andrew E;
Chen, Weiyan;
Chen, Luonan;
Li, Tiejun

Publication type:

Article

Accounting for differential variability in detecting differentially methylated regions.

Published in:

Briefings in Bioinformatics, 2019, v. 20, n. 1, p. 47, doi. 10.1093/bib/bbx097

By:

Wang, Ya;
Teschendorff, Andrew E;
Widschwendter, Martin;
Wang, Shuang

Publication type:

Article

Appraising the causal relevance of DNA methylation for risk of lung cancer.

Published in:

2019

By:

Battram, Thomas;
Richmond, Rebecca C;
Baglietto, Laura;
Haycock, Philip C;
Perduca, Vittorio;
Bojesen, Stig E;
Gaunt, Tom R;
Hemani, Gibran;
Guida, Florence;
Carreras-Torres, Robert;
Hung, Rayjean;
Amos, Christopher I;
Freeman, Joshua R;
Sandanger, Torkjel M;
Nøst, Therese H;
Nordestgaard, Børge G;
Teschendorff, Andrew E;
Polidoro, Silvia;
Vineis, Paolo;
Severi, Gianluca

Publication type:

journal article

A cell-type deconvolution meta-analysis of whole blood EWAS reveals lineage-specific smoking-associated DNA methylation changes.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18618-y

By:

You, Chenglong;
Wu, Sijie;
Zheng, Shijie C.;
Zhu, Tianyu;
Jing, Han;
Flagg, Ken;
Wang, Guangyu;
Jin, Li;
Wang, Sijia;
Teschendorff, Andrew E.

Publication type:

Article

The integrative epigenomic-transcriptomic landscape of ER positive breast cancer.

Published in:

Clinical Epigenetics, 2015, v. 7, p. 1, doi. 10.1186/s13148-015-0159-0

By:

Yang Gao;
Jones, Allison;
Fasching, Peter A.;
Ruebner, Matthias;
Beckmann, Matthias W.;
Widschwendter, Martin;
Teschendorff, Andrew E.

Publication type:

Article

A comparison of reference-based algorithms for correcting cell-type heterogeneity in Epigenome-Wide Association Studies.

Published in:

BMC Bioinformatics, 2017, v. 18, p. 1, doi. 10.1186/s12859-017-1511-5

By:

Teschendorff, Andrew E.;
Breeze, Charles E.;
Zheng, Shijie C.;
Beck, Stephan

Publication type:

Article

Intra-Tumour Signalling Entropy Determines Clinical Outcome in Breast and Lung Cancer.

Published in:

PLoS Computational Biology, 2015, v. 11, n. 3, p. 1, doi. 10.1371/journal.pcbi.1004115

By:

Banerji, Christopher R. S.;
Severini, Simone;
Caldas, Carlos;
Teschendorff, Andrew E.

Publication type:

Article

The Dynamics of DNA Methylation Covariation Patterns in Carcinogenesis.

Published in:

PLoS Computational Biology, 2014, v. 10, n. 7, p. 1, doi. 10.1371/journal.pcbi.1003709

By:

Teschendorff, Andrew E.;
Liu, Xiaoping;
Caren, Helena;
Pollard, Steve M.;
Beck, Stephan;
Widschwendter, Martin;
Chen, Luonan

Publication type:

Article

Cell-type heterogeneity: Why we should adjust for it in epigenome and biomarker studies.

Published in:

Clinical Epigenetics, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13148-022-01253-3

By:

Qi, Luo;
Teschendorff, Andrew E.

Publication type:

Article

Novel epigenetic network biomarkers for early detection of esophageal cancer.

Published in:

Clinical Epigenetics, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13148-022-01243-5

By:

Maity, Alok K.;
Stone, Timothy C.;
Ward, Vanessa;
Webster, Amy P.;
Yang, Zhen;
Hogan, Aine;
McBain, Hazel;
Duku, Margaraet;
Ho, Kai Man Alexander;
Wolfson, Paul;
Graham, David G.;
Beck, Stephan;
Teschendorff, Andrew E.;
Lovat, Laurence B.

Publication type:

Article

DNA methylation aging clocks: challenges and recommendations.

Published in:

Genome Biology, 2019, v. 20, n. 1, p. N.PAG, doi. 10.1186/s13059-019-1824-y

By:

Bell, Christopher G.;
Lowe, Robert;
Adams, Peter D.;
Baccarelli, Andrea A.;
Beck, Stephan;
Bell, Jordana T.;
Christensen, Brock C.;
Gladyshev, Vadim N.;
Heijmans, Bastiaan T.;
Horvath, Steve;
Ideker, Trey;
Issa, Jean-Pierre J.;
Kelsey, Karl T.;
Marioni, Riccardo E.;
Reik, Wolf;
Relton, Caroline L.;
Schalkwyk, Leonard C.;
Teschendorff, Andrew E.;
Wagner, Wolfgang;
Zhang, Kang

Publication type:

Article