Works by Terstappen, Leon W. M. M.

Results: 63

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients.

Published in:

Molecular Oncology, 2025, v. 19, n. 7, p. 2074, doi. 10.1002/1878-0261.13653

By:

Booijink, Richell;
Terstappen, Leon W. M. M.;
Dathathri, Eshwari;
Isebia, Khrystany;
Kraan, Jaco;
Martens, John;
Bansal, Ruchi

Publication type:

Article

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product.

Published in:

Molecular Oncology, 2025, v. 19, n. 7, p. 2133, doi. 10.1002/1878-0261.13565

By:

Stevens, Michiel;
Mentink, Anouk;
Coumans, Frank A. W.;
Dathathri, Eshwari;
Isebia, Khrystany T.;
Kraan, Jaco;
de Wit, Ronald;
Martens, John W. M.;
Terstappen, Leon W. M. M.

Publication type:

Article

Platelet removal by single-step centrifugation.

Published in:

Platelets, 2021, v. 32, n. 4, p. 440, doi. 10.1080/09537104.2020.1779924

By:

Rikkert, Linda G.;
Coumans, Frank A. W.;
Hau, Chi M.;
Terstappen, Leon W. M. M.;
Nieuwland, Rienk

Publication type:

Article

Defining the dimensions of circulating tumor cells in a large series of breast, prostate, colon, and bladder cancer patients.

Published in:

Molecular Oncology, 2021, v. 15, n. 1, p. 116, doi. 10.1002/1878-0261.12802

By:

Mendelaar, Pauline A. J.;
Kraan, Jaco;
Van, Mai;
Zeune, Leonie L.;
Terstappen, Leon W. M. M.;
Oomen‐de Hoop, Esther;
Martens, John W. M.;
Sleijfer, Stefan

Publication type:

Article

Tumour-derived extracellular vesicles in blood of metastatic cancer patients associate with overall survival.

Published in:

2020

By:

Nanou, Afroditi;
Miller, M. Craig;
Zeune, Leonie L.;
de Wit, Sanne;
Punt, Cornelis J. A.;
Groen, Harry J. M.;
Hayes, Daniel F.;
de Bono, Johann S.;
Terstappen, Leon W. M. M.

Publication type:

journal article

Publisher Correction: Organosilicon uptake by biological membranes.

Published in:

2021

By:

Beekman, Pepijn;
Enciso-Martinez, Agustin;
Pujari, Sidharam P.;
Terstappen, Leon W. M. M.;
Zuilhof, Han;
Le Gac, Séverine;
Otto, Cees

Publication type:

Correction Notice

Author Correction: Organosilicon uptake by biological membranes.

Published in:

2021

By:

Beekman, Pepijn;
Enciso-Martinez, Agustin;
Pujari, Sidharam P.;
Terstappen, Leon W. M. M.;
Zuilhof, Han;
Le Gac, Séverine;
Otto, Cees

Publication type:

Correction Notice

Organosilicon uptake by biological membranes.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02155-5

By:

Beekman, Pepijn;
Enciso-Martinez, Agustin;
Pujari, Sidharam P.;
Terstappen, Leon W. M. M.;
Zuilhof, Han T.;
Le Gac, Séverine;
Otto, Cees

Publication type:

Article

A nanowell platform to identify, sort and expand high antibody-producing cells.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-60054-1

By:

Abali, Fikri;
Schasfoort, Richard;
Nijland, Sanne;
Wittenberns, Jelle;
Tibbe, Arjan. G. J.;
den Hartog, Marcel;
Boon, Louis;
Terstappen, Leon W. M. M.

Publication type:

Article

Endothelium-Derived Extracellular Vesicles Associate with Poor Prognosis in Metastatic Colorectal Cancer.

Published in:

Cells (2073-4409), 2020, v. 9, n. 12, p. 2688, doi. 10.3390/cells9122688

By:

Nanou, Afroditi;
Mol, Linda;
Coumans, Frank A. W.;
Koopman, Miriam;
Punt, Cornelis J. A.;
Terstappen, Leon W. M. M.

Publication type:

Article

Construction of repeat-free fluorescence in situ hybridization probes.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 3, p. e20, doi. 10.1093/nar/gkr1123

By:

Swennenhuis, Joost F.;
Foulk, Brad;
Coumans, Frank A.W.;
Terstappen, Leon W. M. M.

Publication type:

Article

Detection of extracellular vesicles in plasma and urine of prostate cancer patients by flow cytometry and surface plasmon resonance imaging.

Published in:

PLoS ONE, 2020, v. 15, n. 6, p. 1, doi. 10.1371/journal.pone.0233443

By:

Rikkert, Linda G.;
de Rond, Leonie;
van Dam, Annemieke;
van Leeuwen, Ton G.;
Coumans, Frank A. W.;
de Reijke, Theo M.;
Terstappen, Leon W. M. M.;
Nieuwland, Rienk

Publication type:

Article

Silica‐coated magnetic nanobeads in a flow enrichment target capture Halbach (FETCH) magnetic separation system for circulating tumor cell enrichment.

Published in:

FEBS Letters, 2025, v. 599, n. 5, p. 724, doi. 10.1002/1873-3468.15094

By:

Liu, Peng;
He, Sitian;
Mentink, Anouk;
Hart, Pieter;
Wu, Yongjun;
Terstappen, Leon W. M. M.;
Jonkheijm, Pascal;
Stevens, Michiel

Publication type:

Article

Importance of circulating tumor cells in newly diagnosed colorectal cancer.

Published in:

International Journal of Oncology, 2015, v. 46, n. 3, p. 1361, doi. 10.3892/ijo.2015.2824

By:

VAN DALUM, GUUS;
STAM, GERRIT-JAN;
SCHOLTEN, LOES F. A.;
MASTBOOM, WALTER J. B.;
VERMES, ISTVAN;
TIBBE, ARJAN G. J.;
DE GROOT, MARCO R.;
TERSTAPPEN, LEON W. M. M.

Publication type:

Article

Measuring antigen expression of cancer cell lines and circulating tumour cells.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-33179-y

By:

Mentink, Anouk;
Isebia, Khrystany T.;
Kraan, Jaco;
Terstappen, Leon W. M. M.;
Stevens, Michiel

Publication type:

Article

Combining rVAR2 and Anti-EpCAM to Increase the Capture Efficiency of Non-Small-Cell Lung Cancer Cell Lines in the Flow Enrichment Target Capture Halbach (FETCH) Magnetic Separation System.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 18, p. 9816, doi. 10.3390/ijms25189816

By:

He, Sitian;
Liu, Peng;
Wu, Yongjun;
Agerbæk, Mette Ø.;
Salanti, Ali;
Terstappen, Leon W. M. M.;
Jonkheijm, Pascal;
Stevens, Michiel

Publication type:

Article

Detecting Blood-Based Biomarkers in Metastatic Breast Cancer: A Systematic Review of Their Current Status and Clinical Utility.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 2, p. 363, doi. 10.3390/ijms18020363

By:

Berghuis, A. M. Sofie;
Koffijberg, Hendrik;
Prakash, Jai;
Terstappen, Leon W. M. M.;
IJzerman, Maarten J.

Publication type:

Article

Improved enrichment of circulating tumor cells from diagnostic leukapheresis product.

Published in:

Cytometry. Part A, 2023, v. 103, n. 11, p. 881, doi. 10.1002/cyto.a.24779

By:

Stevens, Michiel;
Mentink, Anouk;
Nanou, Afroditi;
Coumans, Frank A. W.;
Isebia, Khrystany T.;
Kraan, Jaco;
Hamberg, Paul;
Martens, John W. M.;
Terstappen, Leon W. M. M.

Publication type:

Article

Flat-top illumination profile in an epifluorescence microscope by dual microlens arrays.

Published in:

Cytometry. Part A, 2012, v. 81A, n. 4, p. 324, doi. 10.1002/cyto.a.22029

By:

Coumans, Frank A. W.;
van der Pol, Edwin;
Terstappen, Leon W. M. M.

Publication type:

Article

Automated identification of circulating tumor cells by image cytometry.

Published in:

Cytometry. Part A, 2012, v. 81A, n. 2, p. 138, doi. 10.1002/cyto.a.22002

By:

Scholtens, Tycho M.;
Schreuder, Frederik;
Ligthart, Sjoerd T.;
Swennenhuis, Joost F.;
Greve, Jan;
Terstappen, Leon W. M. M.

Publication type:

Article

CellTracks TDI: An image cytometer for cell characterization.

Published in:

Cytometry. Part A, 2011, v. 79A, n. 3, p. 203, doi. 10.1002/cyto.a.21024

By:

Scholtens, Tycho M.;
Schreuder, Frederik;
Ligthart, Sjoerd T.;
Swennenhuis, Joost F.;
Tibbe, Arjan G. J.;
Greve, Jan;
Terstappen, Leon W. M. M.

Publication type:

Article

Quantifying HER-2 expression on circulating tumor cells by ACCEPT.

Published in:

PLoS ONE, 2017, v. 12, n. 10, p. 1, doi. 10.1371/journal.pone.0186562

By:

Zeune, Leonie;
van Dalum, Guus;
Decraene, Charles;
Proudhon, Charlotte;
Fehm, Tanja;
Neubauer, Hans;
Rack, Brigitte;
Alunni-Fabbroni, Marianna;
Terstappen, Leon W. M. M.;
van Gils, Stephan A.;
Brune, Christoph

Publication type:

Article

Defective and normal haematopoietic stem cells in paroxysmal nocturnal haemoglobinuria.

Published in:

British Journal of Haematology, 1993, v. 84, n. 3, p. 504, doi. 10.1111/j.1365-2141.1993.tb03108.x

By:

Terstappen, Leon W. M. M.;
Nguyen, Mai;
Huang, Shiang;
Lazarus, Hillard M.;
Medof, M. Edward

Publication type:

Article

Magnetic Particles for CTC Enrichment.

Published in:

Cancers, 2020, v. 12, n. 12, p. 3525, doi. 10.3390/cancers12123525

By:

Liu, Peng;
Jonkheijm, Pascal;
Terstappen, Leon W. M. M.;
Stevens, Michiel

Publication type:

Article

Detection of Circulating Tumor Cells in the Diagnostic Leukapheresis Product of Non-Small-Cell Lung Cancer Patients Comparing CellSearch® and ISET.

Published in:

Cancers, 2020, v. 12, n. 4, p. 896, doi. 10.3390/cancers12040896

By:

Tamminga, Menno;
Andree, Kiki C.;
Hiltermann, T. Jeroen N.;
Jayat, Maximilien;
Schuuring, Ed;
van den Bos, Hilda;
Spierings, Diana C. J.;
Lansdorp, Peter M.;
Timens, Wim;
Terstappen, Leon W. M. M.;
Groen, Harry J. M.

Publication type:

Article

Scanning Electron Microscopy of Circulating Tumor Cells and Tumor-Derived Extracellular Vesicles.

Published in:

Cancers, 2018, v. 10, n. 11, p. 416, doi. 10.3390/cancers10110416

By:

Nanou, Afroditi;
Crespo, Mateus;
Flohr, Penny;
De Bono, Johann S.;
Terstappen, Leon W. M. M.

Publication type:

Article

Classification of Cells in CTC-Enriched Samples by Advanced Image Analysis.

Published in:

Cancers, 2018, v. 10, n. 10, p. 377, doi. 10.3390/cancers10100377

By:

de Wit, Sanne;
Zeune, Leonie L.;
Hiltermann, T. Jeroen N.;
Groen, Harry J. M.;
Dalum, Guus van;
Terstappen, Leon W. M. M.

Publication type:

Article

Towards the Biological Understanding of CTC: Capture Technologies, Definitions and Potential to Create Metastasis.

Published in:

Cancers, 2013, v. 5, n. 4, p. 1619, doi. 10.3390/cancers5041619

By:

Barradas, Ana M.C.;
Terstappen, Leon W. M. M.

Publication type:

Article

Phenotypic diversity of CTCs and tdEVs in liquid biopsies of tumour-draining veins is linked to poor prognosis in colorectal cancer.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-024-03259-6

By:

Cieslik, Stefan A.;
Zafra, Andrés G.;
Driemel, Christiane;
Sudarsanam, Monica;
Cieslik, Jan-Philipp;
Flügen, Georg;
Dizdar, Levent;
Krieg, Andreas;
Vaghiri, Sascha;
Ashmawy, Hany;
Fung, Stephen;
Wilms, Miriam;
Terstappen, Leon W. M. M.;
Nanou, Afroditi;
Neubauer, Hans;
Rahbari, Nuh N.;
Knoefel, Wolfram T.;
Stoecklein, Nikolas H.;
Neves, Rui P. L.

Publication type:

Article

Phenotypic diversity of CTCs and tdEVs in liquid biopsies of tumour-draining veins is linked to poor prognosis in colorectal cancer.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-024-03259-6

By:

Cieslik, Stefan A.;
Zafra, Andrés G.;
Driemel, Christiane;
Sudarsanam, Monica;
Cieslik, Jan-Philipp;
Flügen, Georg;
Dizdar, Levent;
Krieg, Andreas;
Vaghiri, Sascha;
Ashmawy, Hany;
Fung, Stephen;
Wilms, Miriam;
Terstappen, Leon W. M. M.;
Nanou, Afroditi;
Neubauer, Hans;
Rahbari, Nuh N.;
Knoefel, Wolfram T.;
Stoecklein, Nikolas H.;
Neves, Rui P. L.

Publication type:

Article

Performance comparison of streptavidin magnetic beads for epcam expressing cancer cell lines for circulating tumor cell (CTC) enrichment in a flow-through immunomagnetic system.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0322375

By:

Liu, Peng;
He, Sitian;
Hart, Pieter;
van Kleef, Alloïse;
Boxum, Stan;
Mentink, Anouk;
Wu, Yongjun;
Terstappen, Leon W. M. M.;
Jonkheijm, Pascal;
Stevens, Michiel

Publication type:

Article

Efficient and error-free fluorescent gene tagging in human organoids without double-strand DNA cleavage.

Published in:

PLoS Biology, 2022, v. 20, n. 1, p. 1, doi. 10.1371/journal.pbio.3001527

By:

Bollen, Yannik;
Hageman, Joris H.;
van Leenen, Petra;
Derks, Lucca L. M.;
Ponsioen, Bas;
Buissant des Amorie, Julian R.;
Verlaan-Klink, Ingrid;
van den Bos, Myrna;
Terstappen, Leon W. M. M.;
van Boxtel, Ruben;
Snippert, Hugo J. G.

Publication type:

Article

DNA Detection by Flow Cytometry using PNA-Modified Metal-Organic Framework Particles.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 17, p. 4180, doi. 10.1002/chem.201605803

By:

Mejia‐Ariza, Raquel;
Rosselli, Jessica;
Breukers, Christian;
Manicardi, Alex;
Terstappen, Leon W. M. M.;
Corradini, Roberto;
Huskens, Jurriaan

Publication type:

Article

Cancer Stem Cells, Epithelial to Mesenchymal Markers, and Circulating Tumor Cells in Small Cell Lung Cancer.

Published in:

2016

By:

Pore, Milind;
Meijer, Coby;
de Bock, Geertruida H.;
Boersma-van Ek, Wytske;
Terstappen, Leon W. M. M.;
Groen, Harry J. M.;
Timens, Wim;
Kruyt, Frank A. E.;
Hiltermann, T. Jeroen N.

Publication type:

journal article

Liquid Biopsy Based Circulating Biomarkers in Metastatic Prostate Cancer.

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.863472

By:

Dathathri, Eshwari;
Isebia, Khrystany T.;
Abali, Fikri;
Lolkema, Martijn P.;
Martens, John W. M.;
Terstappen, Leon W. M. M.;
Bansal, Ruchi

Publication type:

Article

Leukapheresis increases circulating tumour cell yield in non-small cell lung cancer, counts related to tumour response and survival.

Published in:

British Journal of Cancer, 2022, v. 126, n. 3, p. 409, doi. 10.1038/s41416-021-01634-0

By:

Tamminga, Menno;
Andree, Kiki C.;
van den Bos, Hilda;
Hiltermann, T. Jeroen N.;
Mentink, Anouk;
Spierings, Diana C. J.;
Lansdorp, Peter;
Timens, Wim;
Schuuring, Ed;
Terstappen, Leon W. M. M.;
Groen, Harry J. M.

Publication type:

Article

Leukapheresis increases circulating tumour cell yield in non-small cell lung cancer, counts related to tumour response and survival.

Published in:

2022

By:

Tamminga, Menno;
Andree, Kiki C;
van den Bos, Hilda;
Hiltermann, T Jeroen N;
Mentink, Anouk;
Spierings, Diana C J;
Lansdorp, Peter;
Timens, Wim;
Schuuring, Ed;
Terstappen, Leon W M M;
Groen, Harry J M

Publication type:

journal article

Proficiency Testing to Assess Technical Performance for CTC-Processing and Detection Methods in CANCER-ID.

Published in:

Clinical Chemistry, 2021, v. 67, n. 4, p. 631, doi. 10.1093/clinchem/hvaa322

By:

Neves, Rui P. L.;
Ammerlaan, Wim;
Andree, Kiki C.;
Bender, Sebastian;
Cayrefourcq, Laure;
Driemel, Christiane;
Koch, Claudia;
Luetke-Eversloh, Merlin Verena;
Oulhen, Marianne;
Rossi, Elisabetta;
Alix-Panabières, Catherine;
Betsou, Fay;
Farace, Françoise;
Riethdorf, Sabine;
Schlange, Thomas;
Wikman, Harriet;
Zamarchi, Rita;
Pantel, Klaus;
Terstappen, Leon W. M. M.;
Stoecklein, Nikolas H.

Publication type:

Article

Surface Plasmon Resonance is an Analytically Sensitive Method for Antigen Profiling of Extracellular Vesicles.

Published in:

Clinical Chemistry, 2017, v. 63, n. 10, p. 1633, doi. 10.1373/clinchem.2016.271049

By:

Gool, Elmar L.;
Stojanovic, Ivan;
Schasfoort, Richard B. M.;
Sturk, Auguste;
van Leeuwen, Ton G.;
Nieuwland, Rienk;
Terstappen, Leon W. M. M.;
Coumans, Frank A. W.

Publication type:

Article

Detection of Circulating Tumor Cells.

Published in:

Scientifica, 2014, p. 1, doi. 10.1155/2014/819362

By:

de Wit, Sanne;
van Dalum, Guus;
Terstappen, Leon W. M. M.

Publication type:

Article

Multiplex Label Free Characterization of Cancer Cell Lines Using Surface Plasmon Resonance Imaging.

Published in:

Biosensors (2079-6374), 2019, v. 9, n. 2, p. 70, doi. 10.3390/bios9020070

By:

Stojanović, Ivan;
Ruivo, Carolina F.;
van der Velden, Thomas J. G.;
Schasfoort, Richard B. M.;
Terstappen, Leon W. M. M.

Publication type:

Article

Secretome Analysis of Prostate Cancer Cell Lines Reveals Cell Cycle-Dependent PSA Secretion and Potential Biomarkers.

Published in:

Cancers, 2025, v. 17, n. 5, p. 721, doi. 10.3390/cancers17050721

By:

Dathathri, Eshwari;
Peters, Yvette;
Andreoli, Diana;
Bruins, Mel;
Kraan, Jaco;
Terstappen, Leon W. M. M.;
Bansal, Ruchi

Publication type:

Article

In Vivo Detection of Circulating Cancer-Associated Fibroblasts in Breast Tumor Mouse Xenograft: Impact of Tumor Stroma and Chemotherapy.

Published in:

Cancers, 2023, v. 15, n. 4, p. 1127, doi. 10.3390/cancers15041127

By:

Lu, Tao;
Oomens, Lisa;
Terstappen, Leon W. M. M.;
Prakash, Jai

Publication type:

Article

Characterizing Circulating Tumor Cells and Tumor-Derived Extracellular Vesicles in Metastatic Castration-Naive and Castration-Resistant Prostate Cancer Patients.

Published in:

Cancers, 2022, v. 14, n. 18, p. N.PAG, doi. 10.3390/cancers14184404

By:

Isebia, Khrystany T.;
Dathathri, Eshwari;
Verschoor, Noortje;
Nanou, Afroditi;
De Jong, Anouk C.;
Coumans, Frank A. W.;
Terstappen, Leon W. M. M.;
Kraan, Jaco;
Martens, John W. M.;
Bansal, Ruchi;
Lolkema, Martijn P.

Publication type:

Article

StarDist Image Segmentation Improves Circulating Tumor Cell Detection.

Published in:

Cancers, 2022, v. 14, n. 12, p. 2916, doi. 10.3390/cancers14122916

By:

Stevens, Michiel;
Nanou, Afroditi;
Terstappen, Leon W. M. M.;
Driemel, Christiane;
Stoecklein, Nikolas H.;
Coumans, Frank A. W.

Publication type:

Article

Measurement of the Drug Sensitivity of Single Prostate Cancer Cells.

Published in:

Cancers, 2021, v. 13, n. 23, p. 6083, doi. 10.3390/cancers13236083

By:

Abali, Fikri;
Baghi, Narges;
Mout, Lisanne;
Broekmaat, Joska J.;
Tibbe, Arjan G. J.;
Terstappen, Leon W. M. M.

Publication type:

Article

Efficiency of whole genome amplification of Single Circulating Tumor Cells enriched by CellSearch and sorted by FACS.

Published in:

Genome Medicine, 2013, v. 5, n. 11, p. 1, doi. 10.1186/gm510

By:

Swennenhuis, Joost F.;
Reumers, Joke;
Thys, Kim;
Aerssens, Jeroen;
Terstappen, Leon W. M. M.

Publication type:

Article

Circulating tumor cells, disease recurrence and survival in newly diagnosed breast cancer.

Published in:

Breast Cancer Research, 2012, v. 14, n. 5, p. 3333, doi. 10.1186/bcr3333

By:

Franken, Bas;
de Groot, Marco R.;
Mastboom, Walter J. B.;
Vermes, Istvan;
van der Palen, Job;
Tibbe, Arjan G. J.;
Terstappen, Leon W. M. M.

Publication type:

Article

Circulating tumor cells, disease recurrence and survival in newly diagnosed breast cancer.

Published in:

2012

By:

Franken, Bas;
de Groot, Marco R;
Mastboom, Walter Jb;
Vermes, Istvan;
van der Palen, Job;
Tibbe, Arjan Gj;
Terstappen, Leon Wmm;
Mastboom, Walter J B;
Tibbe, Arjan G J;
Terstappen, Leon W M M

Publication type:

journal article

Detection of cancer before distant metastasis.

Published in:

BMC Cancer, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-2407-13-283

By:

Coumans, Frank A. W.;
Siesling, Sabine;
Terstappen, Leon W. M. M.

Publication type:

Article