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Potency Evaluations of Recombinant Botulinum Neurotoxin A1 Mutants Designed to Reduce Toxicity.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 16, p. 8955, doi. 10.3390/ijms25168955
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- Article
Human Induced Pluripotent Stem Cell Derived Neuronal Cells Cultured on Chemically-Defined Hydrogels for Sensitive In Vitro Detection of Botulinum Neurotoxin.
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- Scientific Reports, 2015, p. 14566, doi. 10.1038/srep14566
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- Article
Botulinum neurotoxins A, B, C, E, and F preferentially enter cultured human motor neurons compared to other cultured human neuronal populations.
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- FEBS Letters, 2019, v. 593, n. 18, p. 2675, doi. 10.1002/1873-3468.13508
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- Article
Structural basis of cell surface receptor recognition by botulinum neurotoxin B.
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- Nature, 2006, v. 444, n. 7122, p. 1096, doi. 10.1038/nature05411
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- Article
Mechanism of botulinum neurotoxin B and G entry into hippocampal neurons.
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- Journal of Cell Biology, 2007, v. 179, n. 7, p. 1511, doi. 10.1083/jcb.200707184
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- Article
Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells.
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- Journal of Cell Biology, 2003, v. 162, n. 7, p. 1293, doi. 10.1083/jcb.200305098
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- Article
Structural basis for the unique ganglioside and cell membrane recognition mechanism of botulinum neurotoxin DC.
- Published in:
- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01534-z
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- Article
Cytotoxicity of botulinum neurotoxins reveals a direct role of syntaxin 1 and SNAP-25 in neuron survival.
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- Nature Communications, 2013, v. 4, n. 2, p. 1472, doi. 10.1038/ncomms2462
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- Article
Botulinum Neurotoxin A4 Has a 1000-Fold Reduced Potency Due to Three Single Amino Acid Alterations in the Protein Receptor Binding Domain.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5690, doi. 10.3390/ijms24065690
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- Article
Transformation of a Metal Chelate into a "Catch and Anchor" Inhibitor of Botulinum A Protease.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 5, p. 4303, doi. 10.3390/ijms24054303
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- Article
Resolution of Two Steps in Botulinum Neurotoxin Serotype A1 Light Chain Localization to the Intracellular Plasma Membrane.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 20, p. 11115, doi. 10.3390/ijms222011115
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- Article
Widespread Sequence Variations in VAMP1 across Vertebrates Suggest a Potential Selective Pressure from Botulinum Neurotoxins.
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- PLoS Pathogens, 2014, v. 10, n. 7, p. 1, doi. 10.1371/journal.ppat.1004177
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- Article
Microfluidic tectonics platform: A colorimetric, disposable botulinum toxin enzyme-linked immunosorbent assay system.
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- Electrophoresis, 2004, v. 25, n. 10/11, p. 1705, doi. 10.1002/elps.200405888
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- Article
Analysis of Gene Expression in Induced Pluripotent Stem Cell-Derived Human Neurons Exposed to Botulinum Neurotoxin A Subtype 1 and a Type A Atoxic Derivative.
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- PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0111238
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- Article
Multiple Domains of Tetanus Toxin Direct Entry into Primary Neurons.
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- Traffic, 2014, v. 15, n. 10, p. 1057, doi. 10.1111/tra.12197
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- Article
A Microscale Neuron and Schwann Cell Coculture Model for Increasing Detection Sensitivity of Botulinum Neurotoxin Type A.
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- Toxicological Sciences, 2013, v. 134, n. 1, p. 64, doi. 10.1093/toxsci/kft082
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- Article
Novel Application of Human Neurons Derived from Induced Pluripotent Stem Cells for Highly Sensitive Botulinum Neurotoxin Detection.
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- Toxicological Sciences, 2012, v. 126, n. 2, p. 426, doi. 10.1093/toxsci/kfr354
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- Publication type:
- Article
Critical Analysis of Neuronal Cell and the Mouse Bioassay for Detection of Botulinum Neurotoxins.
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- Toxins, 2019, v. 11, n. 12, p. 713, doi. 10.3390/toxins11120713
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- Article
Botulinum Neurotoxins Can Enter Cultured Neurons Independent of Synaptic Vesicle Recycling.
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- PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0133737
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- Article
Botulinum neurotoxin subtype A2 enters neuronal cells faster than subtype A1
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- FEBS Letters, 2011, v. 585, n. 1, p. 199, doi. 10.1016/j.febslet.2010.11.045
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- Article
Delineating the susceptibility of botulinum neurotoxins to denaturation through thermal effects
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- FEBS Letters, 2008, v. 582, n. 10, p. 1526, doi. 10.1016/j.febslet.2008.03.047
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- Publication type:
- Article
A neuronal cell-based botulinum neurotoxin assay for highly sensitive and specific detection of neutralizing serum antibodies
- Published in:
- FEBS Letters, 2007, v. 581, n. 25, p. 4803, doi. 10.1016/j.febslet.2007.08.078
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- Article
Development of a delivery vehicle for intracellular transport of botulinum neurotoxin antagonists<sup>1</sup><FN ID="FN1"><NO>1</NO>The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Army or the Department of Defense.In conducting the research described in this report, the investigators adhered to the Guide for the Care and Use of Laboratory Animals, National Academy Press, 1996.</FN>
- Published in:
- FEBS Letters, 2002, v. 513, n. 2/3, p. 163, doi. 10.1016/S0014-5793(02)02268-8
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- Article
A Novel Botulinum Neurotoxin, Previously Reported as Serotype H, Has a Hybrid-Like Structure With Regions of Similarity to the Structures of Serotypes A and F and Is Neutralized With Serotype A Antitoxin.
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- 2016
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- Publication type:
- journal article
Botulinum Neurotoxin D Uses Synaptic Vesicle Protein SV2 and Gangliosides as Receptors.
- Published in:
- PLoS Pathogens, 2011, v. 7, n. 3, p. 1, doi. 10.1371/journal.ppat.1002008
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- Article