Found: 26
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Islet amyloid polypeptide aggregation exerts cytotoxic and proinflammatory effects on the islet vasculature in mice.
- Published in:
- Diabetologia, 2022, v. 65, n. 10, p. 1687, doi. 10.1007/s00125-022-05756-9
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- Publication type:
- Article
Low concentration IL-1β promotes islet amyloid formation by increasing hIAPP release from humanised mouse islets in vitro.
- Published in:
- Diabetologia, 2020, v. 63, n. 11, p. 2385, doi. 10.1007/s00125-020-05232-2
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- Publication type:
- Article
Use of the PET ligand florbetapir for in vivo imaging of pancreatic islet amyloid deposits in hIAPP transgenic mice.
- Published in:
- Diabetologia, 2018, v. 61, n. 10, p. 2215, doi. 10.1007/s00125-018-4695-y
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- Publication type:
- Article
The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets.
- Published in:
- Diabetologia, 2016, v. 59, n. 10, p. 2166, doi. 10.1007/s00125-016-4045-x
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- Publication type:
- Article
RNA-seq-based identification of Star upregulation by islet amyloid formation.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2019, v. 32, n. 2, p. 67, doi. 10.1093/protein/gzz022
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- Publication type:
- Article
Loss of perlecan heparan sulfate glycosaminoglycans lowers body weight and decreases islet amyloid deposition in human islet amyloid polypeptide transgenic mice.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2019, v. 32, n. 2, p. 95, doi. 10.1093/protein/gzz041
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- Publication type:
- Article
Human islet amyloid polypeptide‐induced β‐cell cytotoxicity is linked to formation of α‐sheet structure.
- Published in:
- Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 2, p. 1, doi. 10.1002/pro.4854
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- Publication type:
- Article
294-OR: RIPK3-Mediated Necroptosis Is an Alternative Form of TNFa-Induced ß-Cell Death.
- Published in:
- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-294-OR
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- Publication type:
- Article
130-OR: Statin Exposure Increases Star (Steroidogenic Acute Regulatory Protein) Expression in Islets: A Novel Mechanism for ß-Cell Dysfunction and Increased Diabetes Risk?
- Published in:
- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-130-OR
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- Publication type:
- Article
1238-P: The Proinflammatory but Not Cytotoxic Effect of Aggregated IAPP on Islet Endothelial Cells Requires TLR2/4 Signaling.
- Published in:
- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-1238-P
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- Publication type:
- Article
2043-P: Hyaluronan Produced by Inflamed Islet Endothelial Cells Contributes to HIAPP Aggregation.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2043-P
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- Publication type:
- Article
2042-P: Loss of Apoptosis Repressor with Caspase Recruitment Domain Promotes High-Fat Diet Induced Hyperglycemia In Vivo.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2042-P
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- Publication type:
- Article
2040-P: Chronic Activation of CREB by Islet Amyloid Increases Star (Steroidogenic Acute Regulatory Protein) Expression in Islets.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2040-P
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- Publication type:
- Article
2039-P: Plasmin-Mediated Cleavage of Human Islet Amyloid Polypeptide (hIAPP) Protects ß-Cells from Amyloid-Induced Toxicity.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2039-P
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- Publication type:
- Article
2125-P: Increased StAR (Steroidogenic Acute Regulatory Protein) Is Detrimental to ß Cells and Promotes Mitochondrial Dysfunction.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-2125-P
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- Publication type:
- Article
2126-P: Physiological Concentrations of IL-1 Beta Promote Islet Amyloid Deposition by Increasing Beta-Cell Secretion of Human Islet Amyloid Polypeptide.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-2126-P
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- Publication type:
- Article
2124-P: The Tissue Plasminogen Activator (tPA)/Plasmin System Reduces Amyloid Formation by Cleaving Human Islet Amyloid Polypeptide (hIAPP).
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-2124-P
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- Publication type:
- Article
Apoptosis Repressor With Caspase Recruitment Domain Ameliorates Amyloid-Induced β-Cell Apoptosis and JNK Pathway Activation.
- Published in:
- 2017
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- Publication type:
- journal article
Palmitate Induces mRNA Translation and Increases ER Protein Load in Islet β-Cells via Activation of the Mammalian Target of Rapamycin Pathway.
- Published in:
- Diabetes, 2014, v. 63, n. 10, p. 3404, doi. 10.2337/db14-0105
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- Publication type:
- Article
Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model.
- Published in:
- 2012
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- Publication type:
- journal article
Islet β-Cell Endoplasmic Reticulum Stress Precedes the Onset of Type 1 Diabetes in the Nonobese Diabetic Mouse Model.
- Published in:
- Diabetes, 2012, v. 61, n. 4, p. 818, doi. 10.2337/db11-1293
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- Publication type:
- Article
Insulinotropic Effects of Neprilysin and/or Angiotensin Receptor Inhibition in Mice.
- Published in:
- Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.888867
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- Publication type:
- Article
Disease-associated astrocytes and microglia markers are upregulated in mice fed high fat diet.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-39890-0
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- Publication type:
- Article
β-Cell Death in Diabetes: Past Discoveries, Present Understanding, and Potential Future Advances.
- Published in:
- Metabolites (2218-1989), 2021, v. 11, n. 11, p. 796, doi. 10.3390/metabo11110796
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- Publication type:
- Article
Disease-associated astrocytes and microglia markers are upregulated in mice fed high fat diet.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-39890-0
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- Publication type:
- Article
Probing the Meaning of Persistent Propeptide Release in Type 1 Diabetes.
- Published in:
- 2019
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- Publication type:
- journal article