Found: 5

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  • Loss of BAP1 function leads to EZH2-dependent transformation.

    Published in:
    Nature Medicine, 2015, v. 21, n. 11, p. 1344, doi. 10.1038/nm.3947
    By:
    • LaFave, Lindsay M;
    • Béguelin, Wendy;
    • Koche, Richard;
    • Teater, Matt;
    • Spitzer, Barbara;
    • Chramiec, Alan;
    • Papalexi, Efthymia;
    • Keller, Matthew D;
    • Hricik, Todd;
    • Konstantinoff, Katerina;
    • Micol, Jean-Baptiste;
    • Durham, Benjamin;
    • Knutson, Sarah K;
    • Campbell, John E;
    • Blum, Gil;
    • Shi, Xinxu;
    • Doud, Emma H;
    • Krivtsov, Andrei V;
    • Chung, Young Rock;
    • Khodos, Inna
    Publication type:
    Article

  • Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth.

    Published in:
    2018
    By:
    • Fontán, Lorena;
    • Qi Qiao;
    • Hatcher, John M.;
    • Casalena, Gabriella;
    • Us, Ilkay;
    • Teater, Matt;
    • Durant, Matt;
    • Guangyan Du;
    • Min Xia;
    • Bilchuk, Natalia;
    • Chennamadhavuni, Spandan;
    • Palladino, Giuseppe;
    • Inghirami, Giorgio;
    • Philippar, Ulrike;
    • Hao Wu;
    • Scott, David A.;
    • Gray, Nathanael S.;
    • Melnick, Ari;
    • Qiao, Qi;
    • Du, Guangyan
    Publication type:
    journal article

  • Genetic and epigenetic inactivation of SESTRIN1 controls mTORC1 and response to EZH2 inhibition in follicular lymphoma.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 396, p. 1, doi. 10.1126/scitranslmed.aak9969
    By:
    • Oricchio, Elisa;
    • Katanayeva, Natalya;
    • Donaldson, Maria Christine;
    • Sungalee, Stephanie;
    • Joyce, Pasion P.;
    • Béguelin, Wendy;
    • Battistello, Elena;
    • Sanghvi, Viraj R.;
    • Man Jiang;
    • Yanwen Jiang;
    • Teater, Matt;
    • Parmigiani, Anita;
    • Budanov, Andrei V.;
    • Fong Chun Chan;
    • Shah, Sohrab P.;
    • Kridel, Robert;
    • Melnick, Ari M.;
    • Ciriello, Giovanni;
    • Wendel, Hans-Guido
    Publication type:
    Article

  • AICDA drives epigenetic heterogeneity and accelerates germinal center-derived lymphomagenesis.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02595-w
    By:
    • Dominguez, Pilar M.;
    • Melnick, Ari;
    • Shaknovich, Rita;
    • Teater, Matt;
    • Ghione, Paola;
    • Redmond, David;
    • Elemento, Olivier;
    • Zhengming Chen;
    • Ennishi, Daisuke;
    • Scott, David W.;
    • Cimmino, Luisa;
    • Aifantis, Iannis;
    • Chaudhuri, Jayanta;
    • Gascoyne, Randy D.;
    • Inghirami, Giorgio
    Publication type:
    Article

  • EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop.

    Published in:
    Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01029-x
    By:
    • Béguelin, Wendy;
    • Rivas, Martín A.;
    • Calvo Fernández, María T.;
    • Teater, Matt;
    • Purwada, Alberto;
    • Redmond, David;
    • Hao Shen;
    • Challman, Matt F.;
    • Elemento, Olivier;
    • Singh, Ankur;
    • Melnick, Ari M.
    Publication type:
    Article