Works matching AU Taylor, Susan S.

Results: 86

ProKinO: A Unified Resource for Mining the Cancer Kinome.

Published in:

Human Mutation, 2015, v. 36, n. 2, p. 175, doi. 10.1002/humu.22726

By:

McSkimming, Daniel Ian;
Dastgheib, Shima;
Talevich, Eric;
Narayanan, Anish;
Katiyar, Samiksha;
Taylor, Susan S.;
Kochut, Krys;
Kannan, Natarajan

Publication type:

Article

Primary structure of Torpedo californica acetylcholinesterase deduced from its cDNA sequence.

Published in:

Nature, 1986, v. 319, n. 6052, p. 407, doi. 10.1038/319407a0

By:

Schumacher, Mark;
Camp, Shelley;
Maulet, Yves;
Newton, Michael;
MacPhee-Quigley, Kathleen;
Taylor, Susan S.;
Friedmann, Theodore;
Taylor, Palmer

Publication type:

Article

Direct evidence that oncogenic tyrosine kinases and cyclic AMP-dependent protein kinase have homologous ATP-binding sites.

Published in:

Nature, 1984, v. 310, n. 5978, p. 589, doi. 10.1038/310589a0

By:

Kamps, Mark P.;
Taylor, Susan S.;
Sefton, Bartholomew M.

Publication type:

Article

Role of the leucine-rich repeat protein kinase 2 C-terminal tail in domain cross-talk.

Published in:

Biochemical Journal, 2024, v. 481, n. 4, p. 313, doi. 10.1042/BCJ20230477

By:

Sharma, Pallavi Kaila;
Jui-Hung Weng;
Manschwetus, Jascha T.;
Jian Wu;
Wen Ma;
Herberg, Friedrich W.;
Taylor, Susan S.

Publication type:

Article

Single-residue mutation in protein kinase C toggles between cancer and neurodegeneration.

Published in:

Biochemical Journal, 2023, v. 480, n. 16, p. 1299, doi. 10.1042/BCJ20220397

By:

Jones, Alexander C.;
Kornev, Alexandr P.;
Jui-Hung Weng;
Manning, Gerard;
Taylor, Susan S.;
Newton, Alexandra C.

Publication type:

Article

PKA Cβ: a forgotten catalytic subunit of cAMP-dependent protein kinase opens new windows for PKA signaling and disease pathologies.

Published in:

Biochemical Journal, 2021, v. 478, n. 11, p. 2101, doi. 10.1042/BCJ20200867

By:

Taylor, Susan S.;
Wallbott, Maximilian;
Machal, Erik M. F.;
Søberg, Kristoffer;
Ahmed, Faihaa;
Bruystens, Jessica;
Lily Vu;
Baker, Blaine;
Jian Wu;
Raimondi, Francesco;
Ongeri, Elimelda M.;
Herberg, Friedrich W.;
Skålhegg, Bjørn S.

Publication type:

Article

600 ps Molecular dynamics reveals stable substructures and flexible hinge points in cAMP dependent protein kinase.

Published in:

Biopolymers, 1999, v. 50, n. 5, p. 513, doi. 10.1002/(SICI)1097-0282(19991015)50:5<513::AID-BIP5>3.0.CO;2-I

By:

Tsigelny, Igor;
Greenberg, Jerry P.;
Cox, Sarah;
Nichols, William L.;
Taylor, Susan S.;
Ten Eyck, Lynn F.

Publication type:

Article

Catalytic subunit of cAMP-dependent protein kinase: Electrostatic features and peptide recognition.

Published in:

Biopolymers, 1996, v. 39, n. 3, p. 353, doi. 10.1002/(SICI)1097-0282(199609)39:3<353::AID-BIP7>3.0.CO;2-N

By:

Tsigelny, Igor;
Grant, Bruce D.;
Taylor, Susan S.;
Ten Eyck, Lynn F.

Publication type:

Article

RedOx regulation of LRRK2 kinase activity by active site cysteines.

Published in:

NPJ Parkinson's Disease, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41531-024-00683-5

By:

Trilling, Chiara R.;
Weng, Jui-Hung;
Sharma, Pallavi Kaila;
Nolte, Viktoria;
Wu, Jian;
Ma, Wen;
Boassa, Daniela;
Taylor, Susan S.;
Herberg, Friedrich W.

Publication type:

Article

Molecular‐dynamics simulation methods for macromolecular crystallography.

Published in:

Acta Crystallographica: Section D, Structural Biology, 2023, v. 79, n. 1, p. 50, doi. 10.1107/S2059798322011871

By:

Wych, David C.;
Aoto, Phillip C.;
Vu, Lily;
Wolff, Alexander M.;
Mobley, David L.;
Fraser, James S.;
Taylor, Susan S.;
Wall, Michael E.

Publication type:

Article

Uniform nomenclature for the mitochondrial contact site and cristae organizing system.

Published in:

2014

By:

Pfanner, Nikolaus;
van der Laan, Martin;
Amati, Paolo;
Capaldi, Roderick A.;
Caudy, Amy A.;
Chacinska, Agnieszka;
Darshi, Manjula;
Deckers, Markus;
Hoppins, Suzanne;
Tateo Icho;
Jakobs, Stefan;
Jianguo Ji;
Kozjak-Pavlovic, Vera;
Meisinger, Chris;
Odgren, Paul R.;
Sang Ki Park;
Rehling, Peter;
Reichert, Andreas S.;
M. Saeed Sheikh;
Taylor, Susan S.

Publication type:

Opinion

Isoform-specific targeting of PKA to multivesicular bodies.

Published in:

Journal of Cell Biology, 2011, v. 193, n. 2, p. 347, doi. 10.1083/jcb.201010034

By:

Day, Michele E.;
Gaietta, Guido M.;
Sastri, Mira;
Koller, Antonius;
Mackey, Mason R.;
Scott, John D.;
Perkins, Guy A.;
Ellisman, Mark H.;
Taylor, Susan S.

Publication type:

Article

The type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways.

Published in:

Journal of Cell Biology, 2007, v. 178, n. 7, p. 1265, doi. 10.1083/jcb.200705021

By:

Alto, Neal M.;
Weflen, Andrew W.;
Rardin, Matthew J.;
Yarar, Defne;
Lazar, Cheri S.;
Tonikian, Raffi;
Koller, Antonius;
Taylor, Susan S.;
Boone, Charles;
Sidhu, Sachdev S.;
Schmid, Sandra L.;
Hecht, Gall A.;
Dixon, Jack E.

Publication type:

Article

A non-catalytic herpesviral protein reconfigures ERK-RSK signaling by targeting kinase docking systems in the host.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28109-x

By:

Alexa, Anita;
Sok, Péter;
Gross, Fridolin;
Albert, Krisztián;
Kobori, Evan;
Póti, Ádám L.;
Gógl, Gergő;
Bento, Isabel;
Kuang, Ersheng;
Taylor, Susan S.;
Zhu, Fanxiu;
Ciliberto, Andrea;
Reményi, Attila

Publication type:

Article

Protein kinases: A diverse family of related proteins.

Published in:

BioEssays, 1987, v. 7, n. 1, p. 24, doi. 10.1002/bies.950070106

By:

Taylor, Susan S.

Publication type:

Article

Kinase domain dimerization drives RIPK3-dependent necroptosis.

Published in:

Science Signaling, 2018, v. 11, n. 544, p. 1, doi. 10.1126/scisignal.aar2188

By:

Raju, Saravanan;
Whalen, Daniel M.;
Mengistu, Meron;
Swanson, Carter;
Quinn, John G.;
Taylor, Susan S.;
Webster, Joshua D.;
Newton, Kim;
Shaw, Andrey S.

Publication type:

Article

The Rate of NF-κB Nuclear Translocation Is Regulated by PKA and A Kinase Interacting Protein 1.

Published in:

PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0018713

By:

King, Charles C.;
Sastri, Mira;
Chang, Philip;
Pennypacker, Juniper;
Taylor, Susan S.

Publication type:

Article

Identifying Critical Non-Catalytic Residues that Modulate Protein Kinase A Activity.

Published in:

PLoS ONE, 2009, v. 4, n. 3, p. 1, doi. 10.1371/journal.pone.0004746

By:

Kennedy, Eileen J.;
Jie Yang;
Pillus, Lorraine;
Taylor, Susan S.;
Ghosh, Gourisankar

Publication type:

Article

The Forgotten PKAs: New Insights Revealed by the First Crystal Structure of a PKA C Beta Splice Variant, Cβ4ab.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R6147

By:

Bruystens, Jessica H.;
Wu, Jian;
Wallbott, Maximilian;
Bertinetti, Daniela;
Herberg, Friedrich W.;
Taylor, Susan S.

Publication type:

Article

Non‐canonical Recruitment of PKA Catalytic Subunits to RIα‐driven Biomolecular Condensates.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R2418

By:

Hardy, Julia C.;
Zhang, Jason Z.;
Pool, Emily H.;
Choi, Jaclyn L.;
Taylor, Susan S.;
Zhuo, Xin;
Zhang, Jin

Publication type:

Article

AKIP1 protects against cardiac injury via enhanced mitochondrial function.

Published in:

FASEB Journal, 2013, v. 27, p. 657.3, doi. 10.1096/fasebj.27.1_supplement.657.3

By:

Schilling, Jan M;
Haushalter, Kristofer J;
Roth, David M;
Taylor, Susan S;
Sastri, Mira;
Patel, Hemal H

Publication type:

Article

Proteomic analysis of the cAMP/protein kinase A (PKA) signaling pathway identifies PKA as a regulator of cellular response to oxidative stress.

Published in:

FASEB Journal, 2013, v. 27, p. 1143.16, doi. 10.1096/fasebj.27.1_supplement.1143.16

By:

McCann, Thalia;
Wilderman, Andrea S.;
Guo, Yurong;
Taylor, Susan S.;
Insel, Paul A.

Publication type:

Article

Characterization of chchd3; A novel cAMP dependent protein kinase A substrate in mitochondria.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A986, doi. 10.1096/fasebj.21.6.a986-c

By:

Darshi, Manjula;
Schauble, Sharmin;
Yuliang Ma;
Taylor, Susan S.

Publication type:

Article

AKIP1, PKA, and AIF: Human Embryonic Stem Cells Dance Towards Death.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A987, doi. 10.1096/fasebj.21.6.a987-a

By:

King, Charles C.;
Sastri, Mira;
Pennypacker, Juniper;
Taylor, Susan S.

Publication type:

Article

Endogenous protein kinase A inhibitor (PKIα) modulates synaptic activity.

Published in:

Journal of Neuroscience Research, 1998, v. 53, n. 3, p. 269, doi. 10.1002/(SICI)1097-4547(19980801)53:3<269::AID-JNR1>3.0.CO;2-8

By:

de Lecea, Luis;
Criado, José R.;
Rivera, Santiago;
Wen, Wei;
Soriano, Eduardo;
Henriksen, Steven J.;
Taylor, Susan S.;
Gall, Christine M.;
Sutcliffe, J. Gregor

Publication type:

Article

A Generalized Allosteric Mechanism for cis-Regulated Cyclic Nucleotide Binding Domains.

Published in:

PLoS Computational Biology, 2008, v. 4, n. 4, p. 1, doi. 10.1371/journal.pcbi.1000056

By:

Kornev, Alexandr P.;
Taylor, Susan S.;
Eyck, Lynn F. Ten

Publication type:

Article

Decoding the Interactions Regulating the Active State Mechanics of Eukaryotic Protein Kinases.

Published in:

PLoS Biology, 2016, v. 14, n. 11, p. 1, doi. 10.1371/journal.pbio.2000127

By:

Meharena, Hiruy S.;
Fan, Xiaorui;
Ahuja, Lalima G.;
Keshwani, Malik M.;
McClendon, Christopher L.;
Chen, Angela M.;
Adams, Joseph A.;
Taylor, Susan S.

Publication type:

Article

Mapping the Free Energy Landscape of PKA Inhibition and Activation: A Double-Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα.

Published in:

PLoS Biology, 2015, v. 13, n. 12, p. 1, doi. 10.1371/journal.pbio.1002305

By:

Akimoto, Madoka;
McNicholl, Eric Tyler;
Ramkissoon, Avinash;
Moleschi, Kody;
Taylor, Susan S.;
Melacini, Giuseppe

Publication type:

Article

Mapping the Free Energy Landscape of PKA Inhibition and Activation: A Double- Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα.

Published in:

PLoS Biology, 2015, v. 13, n. 11, p. 1, doi. 10.1371/journal.pbio.1002305

By:

Akimoto, Madoka;
McNicholl, Eric Tyler;
Ramkissoon, Avinash;
Moleschi, Kody;
Taylor, Susan S.;
Melacini, Giuseppe

Publication type:

Article

Role of the αC-β4 loop in protein kinase structure and dynamics.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.91980

By:

Jian Wu;
Jonniya, Nisha A.;
Hirakis, Sophia P.;
Olivieri, Cristina;
Veglia, Gianluigi;
Kornev, Alexandr P.;
Taylor, Susan S.

Publication type:

Article

Edmond Fischer's kinase legacy: History of the protein kinase inhibitor and protein kinase A.

Published in:

IUBMB Life, 2023, v. 75, n. 4, p. 311, doi. 10.1002/iub.2714

By:

Taylor, Susan S.;
Herberg, Friedrich W;
Veglia, Gianluigi;
Wu, Jian

Publication type:

Article

Hypothesis: Unifying model of domain architecture for conventional and novel protein kinase C isozymes.

Published in:

IUBMB Life, 2020, v. 72, n. 12, p. 2584, doi. 10.1002/iub.2401

By:

Jones, Alexander C.;
Taylor, Susan S.;
Newton, Alexandra C.;
Kornev, Alexandr P.

Publication type:

Article

Evolution of a dynamic molecular switch.

Published in:

IUBMB Life, 2019, v. 71, n. 6, p. 672, doi. 10.1002/iub.2059

By:

Kornev, Alexandr P.;
Taylor, Susan S.;
Meharena, Hiruy S.

Publication type:

Article

Tuning the "violin" of protein kinases: The role of dynamics‐based allostery.

Published in:

IUBMB Life, 2019, v. 71, n. 6, p. 685, doi. 10.1002/iub.2057

By:

Ahuja, Lalima G.;
Kornev, Alexandr P.;
Taylor, Susan S.

Publication type:

Article

Protein kinase resource: An integrated environment for phosphorylation research.

Published in:

Proteins, 2006, v. 63, n. 1, p. 78, doi. 10.1002/prot.20825

By:

Niedner, Roland H.;
Buzko, Oleksandr V.;
Haste, Nina M.;
Taylor, Ashton;
Gribskov, Michael;
Taylor, Susan S.

Publication type:

Article

Kinase Regulation by Hydrophobic Spine Assembly in Cancer.

Published in:

Molecular & Cellular Biology, 2015, v. 35, n. 1, p. 264, doi. 10.1128/MCB.00943-14

By:

Jiancheng Hu;
Ahuja, Lalima G.;
Meharena, Hiruy S.;
Kannan, Natarajan;
Kornev, Alexandr P.;
Taylor, Susan S.;
Shaw, Andrey S.

Publication type:

Article

Kinases and Pseudokinases: Lessons from RAF.

Published in:

Molecular & Cellular Biology, 2014, v. 34, n. 9, p. 1538, doi. 10.1128/MCB.00057-14

By:

Shaw, Andrey S.;
Kornev, Alexandr P.;
Jiancheng Hu;
Ahuja, Lalima G.;
Taylor, Susan S.

Publication type:

Article

Single Turnover Autophosphorylation Cycle of the PKA RIIβ Holoenzyme.

Published in:

PLoS Biology, 2015, v. 13, n. 7, p. 1, doi. 10.1371/journal.pbio.1002192

By:

Zhang, Ping;
Knape, Matthias J.;
Ahuja, Lalima G.;
Keshwani, Malik M.;
King, Charles C.;
Sastri, Mira;
Herberg, Friedrich W.;
Taylor, Susan S.

Publication type:

Article

Deciphering the Structural Basis of Eukaryotic Protein Kinase Regulation.

Published in:

PLoS Biology, 2013, v. 11, n. 10, p. 1, doi. 10.1371/journal.pbio.1001680

By:

Meharena, Hiruy S.;
Chang, Philip;
Keshwani, Malik M.;
Oruganty, Krishnadev;
Nene, Aishwarya K.;
Kannan, Natarajan;
Taylor, Susan S.;
Kornev, Alexandr P.

Publication type:

Article

Structural and Functional Diversity of the Microbial Kinome.

Published in:

PLoS Biology, 2007, v. 5, n. 3, p. 0467, doi. 10.1371/journal.pbio.0050017

By:

Kannan, Natarajan;
Taylor, Susan S.;
Zhai, Yufeng;
Venter, J. Craig;
Manning, Gerard

Publication type:

Article

Mutations in protein kinase Cγ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition.

Published in:

Science Signaling, 2022, v. 15, n. 753, p. 1, doi. 10.1126/scisignal.abk1147

By:

Pilo, Caila A.;
Baffi, Timothy R.;
Kornev, Alexandr P.;
Kunkel, Maya T.;
Malfavon, Mario;
Chen, Dong-Hui;
Rossitto, Leigh-Ana;
Chen, Daniel X.;
Huang, Liang-Chin;
Longman, Cheryl;
Kannan, Natarajan;
Raskind, Wendy H.;
Gonzalez, David J.;
Taylor, Susan S.;
Gorrie, George;
Newton, Alexandra C.

Publication type:

Article

mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif.

Published in:

Science Signaling, 2021, v. 14, n. 678, p. 1, doi. 10.1126/scisignal.abe4509

By:

Baffi, Timothy R.;
Lordén, Gema;
Wozniak, Jacob M.;
Feichtner, Andreas;
Yeung, Wayland;
Kornev, Alexandr P.;
King, Charles C.;
Del Rio, Jason C.;
Limaye, Ameya J.;
Bogomolovas, Julius;
Gould, Christine M.;
Chen, Ju;
Kennedy, Eileen J.;
Kannan, Natarajan;
Gonzalez, David J.;
Stefan, Eduard;
Taylor, Susan S.;
Newton, Alexandra C.

Publication type:

Article

Allosteric linkers in cAMP signalling.

Published in:

Biochemical Society Transactions, 2014, v. 42, n. 1, p. 139, doi. 10.1042/BST20130257

By:

Akimoto, Madoka;
Moleschi, Kody;
Boulton, Stephen;
VanSchouwen, Bryan;
Selvaratnam, Rajeevan;
Taylor, Susan S.;
Melacini, Giuseppe

Publication type:

Article

Pseudokinases from a structural perspective.

Published in:

Biochemical Society Transactions, 2013, v. 41, n. 4, p. 981, doi. 10.1042/BST20130120

By:

Taylor, Susan S.;
Shaw, Andrey;
Jiancheng Hu;
Meharena, Hiruy S.;
Kornev, Alexandr

Publication type:

Article

Crystal structure of a transition state mimic of the catalytic subunit of cAMP-dependent protein kinase.

Published in:

Nature Structural Biology, 2002, v. 9, n. 4, p. 273, doi. 10.1038/nsb780

By:

Madhusudan;
Akamine, Pearl;
Xuong, Nguyen-Huu;
Taylor, Susan S.

Publication type:

Article

PKA: assembly of dynamic macromolecular signaling.

Published in:

2011

By:

Taylor, Susan S.;
Ilouz, Ronit;
Darshi, Manjula;
Sarma, Ganapathy;
Kornev, Alexandr;
Ping Zhang

Publication type:

Abstract

LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domains.

Published in:

PLoS Biology, 2022, v. 20, n. 2, p. 1, doi. 10.1371/journal.pbio.3001427

By:

Weng, Jui-Hung;
Aoto, Phillip C.;
Lorenz, Robin;
Wu, Jian;
Schmidt, Sven H.;
Manschwetus, Jascha T.;
Kaila-Sharma, Pallavi;
Silletti, Steve;
Mathea, Sebastian;
Chatterjee, Deep;
Knapp, Stefan;
Herberg, Friedrich W.;
Taylor, Susan S.

Publication type:

Article

Structural analyses of the PKA RIIβ holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma.

Published in:

PLoS Biology, 2020, v. 18, n. 12, p. 1, doi. 10.1371/journal.pbio.3001018

By:

Lu, Tsan-Wen;
Aoto, Phillip C.;
Weng, Jui-Hung;
Nielsen, Cole;
Cash, Jennifer N.;
Hall, James;
Zhang, Ping;
Simon, Sanford M.;
Cianfrocco, Michael A.;
Taylor, Susan S.

Publication type:

Article

Allostery through the computational microscope: cAMP activation of a canonical signalling domain.

Published in:

Nature Communications, 2015, v. 6, n. 7, p. 7588, doi. 10.1038/ncomms8588

By:

Malmstrom, Robert D.;
Kornev, Alexandr P.;
Taylor, Susan S.;
Amaro, Rommie E.

Publication type:

Article

The identification of novel cyclic AMP-dependent protein kinase anchoring proteins using bioinformatic filters and peptide arrays.

Published in:

PEDS: Protein Engineering, Design & Selection, 2011, v. 24, n. 3, p. 333, doi. 10.1093/protein/gzq106

By:

McLaughlin, William A.;
Hou, Tingjun;
Taylor, Susan S.;
Wang, Wei

Publication type:

Article