Works by Taylor, Palmer

Results: 69

Click-chemistry-derived oxime library reveals efficient reactivators of nerve agent-inhibited butyrylcholinesterase suitable for pseudo-catalytic bioscavenging.

Published in:

Archives of Toxicology, 2025, v. 99, n. 5, p. 2107, doi. 10.1007/s00204-025-03985-6

By:

Čadež, Tena;
Maček Hrvat, Nikolina;
Šinko, Goran;
Kalisiak, Jarosław;
Radić, Zoran;
Fokin, Valery V.;
Sharpless, Karl Barry;
Taylor, Palmer;
Kovarik, Zrinka

Publication type:

Article

Positron emission tomography evaluation of oxime countermeasures in live rats using the tracer O‐(2‐[18F]fluoroethyl)‐O‐(p‐nitrophenyl)methylphosphonate [18F]‐VXS.

Published in:

Annals of the New York Academy of Sciences, 2020, v. 1479, n. 1, p. 180, doi. 10.1111/nyas.14363

By:

Hayes, Thomas R.;
Blecha, Joseph E.;
Chao, Chih‐Kai;
Huynh, Tony L.;
VanBrocklin, Henry F.;
Zinn, Kurt R.;
Taylor, Palmer W.;
Gerdes, John M.;
Thompson, Charles M.

Publication type:

Article

Limitations in current acetylcholinesterase structure-based design of oxime antidotes for organophosphate poisoning.

Published in:

Annals of the New York Academy of Sciences, 2016, v. 1378, n. 1, p. 41, doi. 10.1111/nyas.13128

By:

Kovalevsky, Andrey;
Blumenthal, Donald K.;
Cheng, Xiaolin;
Taylor, Palmer;
Radić, Zoran

Publication type:

Article

Structural insights into the exquisite selectivity of neurexin/neuroligin synaptic interactions.

Published in:

EMBO Journal, 2010, v. 29, n. 14, p. 2461, doi. 10.1038/emboj.2010.123

By:

Leone, Philippe;
Comoletti, Davide;
Ferracci, Géraldine;
Conrod, Sandrine;
Garcia, Simon U.;
Taylor, Palmer;
Bourne, Yves;
Marchot, Pascale

Publication type:

Article

Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor.

Published in:

EMBO Journal, 2009, v. 28, n. 19, p. 3040, doi. 10.1038/emboj.2009.227

By:

Hibbs, Ryan E.;
Sulzenbacher, Gerlind;
Jianxin Shi;
Talley, Todd T.;
Conrod, Sandrine;
Kem, William R.;
Taylor, Palmer;
Marchot, Pascale;
Bourne, Yves

Publication type:

Article

Crystal structure of a Cbtx–AChBP complex reveals essential interactions between snake α-neurotoxins and nicotinic receptors.

Published in:

2006

By:

Bourne, Yves;
Talley, Todd T.;
Hansen, Scott B.;
Taylor, Palmer;
Marchot, Pascale

Publication type:

Correction Notice

Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations.

Published in:

EMBO Journal, 2005, v. 24, n. 20, p. 3635, doi. 10.1038/sj.emboj.7600828

By:

Hansen, Scott B.;
Sulzenbacher, Gerlind;
Huxford, Tom;
Marchot, Pascale;
Taylor, Palmer;
Bourne, Yves

Publication type:

Article

Crystal structure of a Cbtx–AChBP complex reveals essential interactions between snakeα-neurotoxins and nicotinic receptors.

Published in:

EMBO Journal, 2005, v. 24, n. 8, p. 1512, doi. 10.1038/sj.emboj.7600620

By:

Bourne, Yves;
Talley, Todd T.;
Hansen, Scott B.;
Taylor, Palmer;
Marchot, Pascale

Publication type:

Article

Planarian cholinesterase: molecular and functional characterization of an evolutionarily ancient enzyme to study organophosphorus pesticide toxicity.

Published in:

Archives of Toxicology, 2018, v. 92, n. 3, p. 1161, doi. 10.1007/s00204-017-2130-7

By:

Hagstrom, Danielle;
Ho, Alicia;
Tsai, Eileen S.;
He, Yingtian;
Collins, Eva-Maria S.;
Zhang, Siqi;
Jahromi, Aryo;
Radić, Zoran;
Taylor, Palmer;
Kaj, Kelson J.

Publication type:

Article

Planarian cholinesterase: in vitro characterization of an evolutionarily ancient enzyme to study organophosphorus pesticide toxicity and reactivation.

Published in:

Archives of Toxicology, 2017, v. 91, n. 8, p. 2837, doi. 10.1007/s00204-016-1908-3

By:

Hagstrom, Danielle;
Hirokawa, Hideto;
Zhang, Limin;
Radic, Zoran;
Taylor, Palmer;
Collins, Eva-Maria

Publication type:

Article

Butyrylcholinesterase identification in a phenylvalerate esterase-enriched fraction sensitive to low mipafox concentrations in chicken brain.

Published in:

Archives of Toxicology, 2017, v. 91, n. 2, p. 909, doi. 10.1007/s00204-016-1670-6

By:

Mangas, Iris;
Radić, Zoran;
Taylor, Palmer;
Ghassemian, Majid;
Candela, Héctor;
Vilanova, Eugenio;
Estévez, Jorge

Publication type:

Article

SPINAL NICOTINIC RECEPTOR ACTIVITY IN A GENETIC MODEL OF HYPERTENSION.

Published in:

Clinical & Experimental Hypertension, 2001, v. 23, n. 7, p. 555, doi. 10.1081/CEH-100106826

By:

Khan, Imran M.;
Stanislaus, Shanaka;
Zhang, Limin;
Vaughn, Duke;
Printz, Morton P.;
Yaksh, Tony L.;
Taylor, Palmer

Publication type:

Article

Clash of Symbols.

Published in:

1962

By:

Taylor, Wm. Palmer

Publication type:

Letter

More Replies on China.

Published in:

1961

By:

Wm. Taylor, Palmer

Publication type:

Letter

Letters to the Editor.

Published in:

1956

By:

Taylor, Wm. Palmer

Publication type:

Letter

The Arg451Cys-Neuroligin-3 Mutation Associated with Autism Reveals a Defect in Protein Processing.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 20, p. 4889, doi. 10.1523/JNEUROSCI.0468-04.2004

By:

Comoletti, Davide;
De Jaco, Antonella;
Jennings, Lori L.;
Flynn, Robyn E.;
Gaietta, Guido;
Tsigelny, Igor;
Ellisman, Mark H.;
Taylor, Palmer

Publication type:

Article

Control of Cation Permeation through the Nicotinic Receptor Channel.

Published in:

PLoS Computational Biology, 2008, v. 4, n. 2, p. 1, doi. 10.1371/journal.pcbi.0040041

By:

Hai-Long Wang;
Xiaolin Cheng;
Taylor, Palmer;
McCammon, J. Andrew;
Sine, Steven M.

Publication type:

Article

Pharm.D. Pathways to Biomedical Research: The National Institutes of Health Special Conference on Pharmacy Research.

Published in:

2008

By:

Figg, William D.;
Chau, Cindy H.;
Okita, Richard;
Preusch, Peter;
Tracy, Timothy S.;
McLeod, Howard;
Reed, Michael;
Pieper, John;
Knoell, Daren;
Miller, Ken;
Speedie, Marilyn;
Blouin, Robert;
Kroboth, Patricia;
Koda-Kimble, Mary Anne;
Taylor, Palmer;
Cohen, Jordan;
Giacomini, Kathy

Publication type:

Proceeding

Nearrings of Functions Determined by a Collection of Invariant Subgroups.

Published in:

Southeast Asian Bulletin of Mathematics, 2024, v. 48, n. 4, p. 459

By:

Boudreaux, Matthew G.;
Cannon, G. Alan;
Palmer, Taylor R.;
Troxclair, Tyler C.

Publication type:

Article

Mechanistic studies of new oximes reactivators of human butyryl cholinesterase inhibited by cyclosarin and sarin.

Published in:

Journal of Biomolecular Structure & Dynamics, 2017, v. 35, n. 6, p. 1272, doi. 10.1080/07391102.2016.1178173

By:

de Lima, Willian E. Amaral;
Francisco, Ander;
da Cunha, Elaine F.F.;
Radic, Zoran;
Taylor, Palmer;
França, Tanos C.C.;
Ramalho, Teodorico C.

Publication type:

Article

Design and Synthesis of Nicotinic Acetylcholine Receptor Antagonists and their Effect on Cognitive Impairment.

Published in:

Chemical Biology & Drug Design, 2016, v. 87, n. 1, p. 39, doi. 10.1111/cbdd.12627

By:

Jaikhan, Pattaporn;
Boonyarat, Chantana;
Arunrungvichian, Kuntarat;
Taylor, Palmer;
Vajragupta, Opa

Publication type:

Article

A single post‐exposure oxime RS194B treatment rapidly reactivates acetylcholinesterase and reverses acute symptoms in macaques exposed to diethylphosphorothioate parathion and chlorpyrifos insecticides.

Published in:

Journal of Neurochemistry, 2024, v. 168, n. 4, p. 370, doi. 10.1111/jnc.15777

By:

Rosenberg, Yvonne J.;
Garcia, Kelly;
Diener, Justin;
Sullivan, Dennis;
Donahue, Scott;
Mao, Lingjun;
Lees, Jonathan;
Jiang, Xiaoming;
Urban, Lori A.;
Momper, Jeremiah D.;
Ho, Kwok‐Yiu;
Taylor, Palmer

Publication type:

Article

Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes.

Published in:

Biochemical Journal, 2013, v. 450, n. 1, p. 231, doi. 10.1042/BJ20121612

By:

RADIĆ, Zoran;
DALE, Trevor;
KOVARIK, Zrinka;
BEREND, Suzana;
GARCIA, Edzna;
ZHANG, Limin;
AMITAI, Gabriel;
GREEN, Carol;
RADI, BoŽica;
DUGGAN, Brendan M.;
AJAMI, Dariush;
REBEK Jr, Julius;
TAYLOR, Palmer

Publication type:

Article

The Cyclic Imine Core Common to the Marine Macrocyclic Toxins Is Sufficient to Dictate Nicotinic Acetylcholine Receptor Antagonism.

Published in:

Marine Drugs, 2024, v. 22, n. 4, p. 149, doi. 10.3390/md22040149

By:

Bourne, Yves;
Sulzenbacher, Gerlind;
Chabaud, Laurent;
Aráoz, Rómulo;
Radić, Zoran;
Conrod, Sandrine;
Taylor, Palmer;
Guillou, Catherine;
Molgó, Jordi;
Marchot, Pascale

Publication type:

Article

Interactions of Nereistoxin and Its Analogs with Vertebrate Nicotinic Acetylcholine Receptors and Molluscan ACh Binding Proteins.

Published in:

Marine Drugs, 2022, v. 20, n. 1, p. 49, doi. 10.3390/md20010049

By:

Kem, William R.;
Andrud, Kristin;
Bruno, Galen;
Xing, Hong;
Soti, Ferenc;
Talley, Todd T.;
Taylor, Palmer

Publication type:

Article

Lophotoxins: Irreversible active-site-directed inhibitors of nicotinic acetylcholine receptors.

Published in:

Drug Development Research, 1991, v. 24, n. 4, p. 297, doi. 10.1002/ddr.430240402

By:

Abramson, Stewart N.;
Fenical, William;
Taylor, Palmer

Publication type:

Article

Primary structure of Torpedo californica acetylcholinesterase deduced from its cDNA sequence.

Published in:

Nature, 1986, v. 319, n. 6052, p. 407, doi. 10.1038/319407a0

By:

Schumacher, Mark;
Camp, Shelley;
Maulet, Yves;
Newton, Michael;
MacPhee-Quigley, Kathleen;
Taylor, Susan S.;
Friedmann, Theodore;
Taylor, Palmer

Publication type:

Article

Heredity and the autonomic nervous system in human hypertension.

Published in:

Current Hypertension Reports, 2000, v. 2, n. 1, p. 16, doi. 10.1007/s11906-000-0053-8

By:

O’Connor, Daniel;
Insel, Paul;
Ziegler, Michael;
Hook, Vivian;
Smith, Douglas;
Hamilton, Bruce;
Taylor, Palmer;
Parmer, Robert

Publication type:

Article

Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site.

Published in:

EMBO Journal, 2003, v. 22, n. 1, p. 1, doi. 10.1093/emboj/cdg005

By:

Bourne, Yves;
Taylor, Palmer;
Radi&cacute, Zoran;
Marchot, Pascale

Publication type:

Article

Rapid binding of a cationic active site inhibitor to wild type and mutant mouse acetylcholinesterase: Brownian dynamics simulation including diffusion in the active site gorge.

Published in:

Biopolymers, 1998, v. 46, n. 7, p. 465, doi. 10.1002/(SICI)1097-0282(199812)46:7<465::AID-BIP4>3.0.CO;2-Y

By:

Tara, Sylvia;
Elcock, Adrian H.;
Kirchhoff, Paul D.;
Briggs, James M.;
Radic, Zoran;
Taylor, Palmer;
McCammon, J. Andrew

Publication type:

Article

Peripheral Site Ligands Accelerate Inhibition of Acetylcholinesterase by Neutral Organophosphates.

Published in:

Journal of Applied Toxicology, 2001, v. 21, n. 0, p. S13, doi. 10.1002/jat.790

By:

Radić, Zoran;
Taylor, Palmer

Publication type:

Article

An in vivo biosensor for neurotransmitter release and in situ receptor activity.

Published in:

Nature Neuroscience, 2010, v. 13, n. 1, p. 127, doi. 10.1038/nn.2469

By:

Quoc-Thang Nguyen;
Schroeder, Lee F.;
Mank, Marco;
Muller, Arnaud;
Taylor, Palmer;
Griesbeck, Oliver;
Kleinfeld, David

Publication type:

Article

Nicotinic acetylcholine receptor distribution in relation to spinal neurotransmission pathways.

Published in:

Journal of Comparative Neurology, 2003, v. 467, n. 1, p. 44, doi. 10.1002/cne.10913

By:

Imran Khan;
Hitoshi Osaka;
Shanaka Stanislaus;
Rosa M. Calvo;
Tom Deerinck;
Tony L. Yaksh;
Palmer Taylor

Publication type:

Article

Ligand design for human acetylcholinesterase and nicotinic acetylcholine receptors, extending beyond the conventional and canonical.

Published in:

Journal of Neurochemistry, 2021, v. 158, n. 6, p. 1217, doi. 10.1111/jnc.15335

By:

Taylor, Palmer;
Shyong, Yan‐Jye;
Samskey, Nathan;
Ho, Kwok‐Yiu;
Radic', Zoran;
Fenical, William;
Sharpless, K. Barry;
Kovarik, Zrinka;
Camacho‐Hernandez, Gisela‐Andrea

Publication type:

Article

Cyclic imine toxins from dinoflagellates: a growing family of potent antagonists of the nicotinic acetylcholine receptors.

Published in:

Journal of Neurochemistry, 2017, v. 142, p. 41, doi. 10.1111/jnc.13995

By:

Molgó, Jordi;
Marchot, Pascale;
Aráoz, Rómulo;
Benoit, Evelyne;
Iorga, Bogdan I.;
Zakarian, Armen;
Taylor, Palmer;
Bourne, Yves;
Servent, Denis

Publication type:

Article

Distinctions in Ligand Binding Sites on the Nicotinic Acetylcholine Receptora.

Published in:

Annals of the New York Academy of Sciences, 1991, v. 625, n. 1, p. 568, doi. 10.1111/j.1749-6632.1991.tb33893.x

By:

TAYLOR, PALMER;
ABRAMSON, STEWART N.;
JOHNSON, DAVID A.;
VALENZUELA, C. FERNANDO;
HERZ, JEFREY

Publication type:

Article

Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel.

Published in:

Nature, 2004, v. 430, n. 7002, p. 896, doi. 10.1038/nature02753

By:

Bouzat, Cecilia;
Gumilar, Fernanda;
Spitzmaul, Guillermo;
Wang, Hai-Long;
Rayes, Diego;
Hansen, Scott B.;
Taylor, Palmer;
Sine, Steven M.

Publication type:

Article

Inherited genetic variants in autism-related CNTNAP2 show perturbed trafficking and ATF6 activation.

Published in:

Human Molecular Genetics, 2012, v. 21, n. 21, p. 4761, doi. 10.1093/hmg/dds320

By:

Falivelli, Giulia;
De Jaco, Antonella;
Favaloro, Flores Lietta;
Kim, Hyuck;
Wilson, Jennifer;
Dubi, Noga;
Ellisman, Mark H.;
Abrahams, Brett S.;
Taylor, Palmer;
Comoletti, Davide

Publication type:

Article

Characterizing Ligand-Gated Ion Channel Receptors with Genetically Encoded Ca++ Sensors.

Published in:

PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0016519

By:

Yamauchi, John G.;
Nemecz, Ákos;
Nguyen, Quoc Thang;
Muller, Arnaud;
Schroeder, Lee F.;
Talley, Todd T.;
Lindstrom, Jon;
Kleinfeld, David;
Taylor, Palmer

Publication type:

Article

Cover Picture: Angew. Chem. Int. Ed. 6/2002.

Published in:

Angewandte Chemie International Edition, 2002, v. 41, n. 6, p. 875, doi. 10.1002/1521-3773(20020315)41:6<875::AID-ANIE875>3.0.CO;2-Y

By:

Lewis, Warren G.;
Green, Luke G.;
Grynszpan, Flavio;
Radić, Zoran;
Carlier, Paul R.;
Taylor, Palmer;
Finn, M. G.;
Sharpless, K. Barry

Publication type:

Article

Click Chemistry In Situ: Acetylcholinesterase as a Reaction Vessel for the Selective Assembly of a Femtomolar Inhibitor from an Array of Building Blocks.

Published in:

Angewandte Chemie International Edition, 2002, v. 41, n. 6, p. 1053, doi. 10.1002/1521-3773(20020315)41:6<1053::AID-ANIE1053>3.0.CO;2-4

By:

Lewis, Warren G.;
Green, Luke G.;
Grynszpan, Flavio;
Radić, Zoran;
Carlier, Paul R.;
Taylor, Palmer;
Finn, M. G.;
Sharpless, K. Barry

Publication type:

Article

Cyber-security, the IRS and You: How to Stay Up-to-Date with Changing Technologies.

Published in:

Journal of Tax Practice & Procedure, 2016, v. 18, n. 3, p. 43

By:

Jones, Larry;
Palmer, Taylor

Publication type:

Article

Main Immunogenic Region Structure Promotes Binding of Conformation-Dependent Myasthenia Gravis Autoantibodies, Nicotinic Acetylcholine Receptor Conformation Maturation, and Agonist Sensitivity.

Published in:

Journal of Neuroscience, 2009, v. 29, n. 44, p. 13898, doi. 10.1523/JNEUROSCI.2833-09.2009

By:

Jie Luo;
Taylor, Palmer;
Losen, Mario;
de Baets, Marc H.;
Shelton, G. Diane;
Lindstrom, Jon

Publication type:

Article

Targeting of Acetylcholinesterase in Neurons In Vivo: A Dual Processing Function for the Proline-Rich Membrane Anchor Subunit and the Attachment Domain on the Catalytic Subunit.

Published in:

Journal of Neuroscience, 2009, v. 29, n. 14, p. 4519, doi. 10.1523/JNEUROSCI.3863-08.2009

By:

Dobbertin, Alexandre;
Hrabovska, Anna;
Dembele, Korami;
Camp, Shelley;
Taylor, Palmer;
Krejci, Eric;
Bernard, Véronique

Publication type:

Article

Acetylcholinesterase Expression in Muscle Is Specifically Controlled by a Promoter-Selective Enhancesome in the First Intron.

Published in:

Journal of Neuroscience, 2008, v. 28, n. 10, p. 2459, doi. 10.1523/JNEUROSCI.4600-07.2008

By:

Camp, Shelley;
De Jaco, Antonella;
Limin Zhang;
Marquez, Michael;
De La Torre, Brian;
Taylor, Palmer

Publication type:

Article

Acetylcholinesterase and Nicotinic Acetylcholine Receptor Expression Diverge in Muscular Dysgenic Mice Lacking the L-Type Calcium Channel.

Published in:

Journal of Neurochemistry, 1996, v. 67, n. 1, p. 111, doi. 10.1046/j.1471-4159.1996.67010111.x

By:

Luo, Z. David;
Pincon-Raymond, Martine;
Taylor, Palmer

Publication type:

Article

Epitope Mapping of Form-Specific and Nonspecific Antibodies to Acetylcholinesterase.

Published in:

Journal of Neurochemistry, 1993, v. 61, n. 6, p. 2124, doi. 10.1111/j.1471-4159.1993.tb07450.x

By:

Wasserman, Linda;
Doctor, Bhupendra P.;
Gentry, Mary K.;
Taylor, Palmer

Publication type:

Article

Studies on the Topography of the Catalytic Site of Acetylcholinesterase Using Polyclonal and Monoclonal Antibodies.

Published in:

Journal of Neurochemistry, 1990, v. 55, n. 3, p. 756, doi. 10.1111/j.1471-4159.1990.tb04556.x

By:

Ogert, Robert A.;
Gentry, Mary K.;
Richardson, Earl C.;
Al, Carolyn D.;
Abramson, Stewart N.;
Alving, Carl R.;
Taylor, Palmer;
Doctor, B. P.

Publication type:

Article

Congenital hypothyroidism mutations affect common folding and trafficking in the α/β-hydrolase fold proteins.

Published in:

FEBS Journal, 2012, v. 279, n. 23, p. 4293, doi. 10.1111/febs.12019

By:

Jaco, Antonella;
Dubi, Noga;
Camp, Shelley;
Taylor, Palmer

Publication type:

Article

Reversal of Tabun Toxicity Enabled by a Triazole‐Annulated Oxime Library—Reactivators of Acetylcholinesterase.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 16, p. 4100, doi. 10.1002/chem.201805051

By:

Kovarik, Zrinka;
Kalisiak, Jarosław;
Hrvat, Nikolina Maček;
Katalinić, Maja;
Zorbaz, Tamara;
Žunec, Suzana;
Green, Carol;
Radić, Zoran;
Fokin, Valery V.;
Sharpless, K. Barry;
Taylor, Palmer

Publication type:

Article