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Evaluation of Human Hepatocyte Drug Metabolism Carrying High-Risk or Protection-Associated Liver Disease Genetic Variants.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 17, p. 13406, doi. 10.3390/ijms241713406
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- Article
The Combination of a Human Biomimetic Liver Microphysiology System with BIOLOGXsym, a Quantitative Systems Toxicology (QST) Modeling Platform for Macromolecules, Provides Mechanistic Understanding of Tocilizumab- and GGF2-Induced Liver Injury.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 11, p. 9692, doi. 10.3390/ijms24119692
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- Article
A Quantitative Systems Pharmacology Platform Reveals NAFLD Pathophysiological States and Targeting Strategies.
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- Metabolites (2218-1989), 2022, v. 12, n. 6, p. 528, doi. 10.3390/metabo12060528
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- Article
Quantifying the progression of non-alcoholic fatty liver disease in human biomimetic liver microphysiology systems with fluorescent protein biosensors.
- Published in:
- Experimental Biology & Medicine, 2021, v. 246, n. 22, p. 2420, doi. 10.1177/15353702211009228
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- Article
A systems‐level study reveals host‐targeted repurposable drugs against SARS‐CoV‐2 infection.
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- Molecular Systems Biology, 2021, v. 17, n. 8, p. 1, doi. 10.15252/msb.202110239
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- Article
Inhibition of RPS6K reveals context-dependent Akt activity in luminal breast cancer cells.
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- PLoS Computational Biology, 2021, v. 17, n. 6, p. 1, doi. 10.1371/journal.pcbi.1009125
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- Article
Spatial domain analysis predicts risk of colorectal cancer recurrence and infers associated tumor microenvironment networks.
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- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17083-x
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- Article
QuartataWeb: Integrated Chemical–Protein-Pathway Mapping for Polypharmacology and Chemogenomics.
- Published in:
- Bioinformatics, 2020, v. 36, n. 12, p. 3935, doi. 10.1093/bioinformatics/btaa210
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- Article
Opportunities and Challenges in Implementation of Multiparameter Single Cell Analysis Platforms for Clinical Translation.
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- CTS: Clinical & Translational Science, 2018, v. 11, n. 3, p. 267, doi. 10.1111/cts.12536
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- Article
Clinically Observed Estrogen Receptor Alpha Mutations within the Ligand-Binding Domain Confer Distinguishable Phenotypes.
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- Oncology, 2018, v. 94, n. 3, p. 176, doi. 10.1159/000485510
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- Article
Control of oxygen tension recapitulates zone-specific functions in human liver microphysiology systems.
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- Experimental Biology & Medicine, 2017, v. 242, n. 16, p. 1617, doi. 10.1177/1535370217703978
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- Publication type:
- Article
Liver metastases: Microenvironments and ex-vivo models.
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- Experimental Biology & Medicine, 2016, v. 241, n. 15, p. 1639, doi. 10.1177/1535370216658144
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- Article
A human liver microphysiology platform for investigating physiology, drug safety, and disease models.
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- Experimental Biology & Medicine, 2016, v. 241, n. 1, p. 101, doi. 10.1177/1535370215592121
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- Article
Fluorescent protein biosensors applied to microphysiological systems.
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- Experimental Biology & Medicine, 2015, v. 240, n. 6, p. 795, doi. 10.1177/1535370215584934
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- Article
BalestraWeb: efficient online evaluation of drug–target interactions.
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- 2015
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- Publication type:
- Web Site Review
In vitro platforms for evaluating liver toxicity.
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- Experimental Biology & Medicine, 2014, v. 239, n. 9, p. 1180, doi. 10.1177/1535370214531872
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- Article
Workshop Report: Developing Microphysiological Systems for Use as Regulatory Tools.
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- Altex, 2014, v. 31, n. 3, p. 1, doi. 10.14573/altex.1405151
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- Article
Developing Microphysiological Systems for Use as Regulatory Tools - Challenges and Opportunities.
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- Altex, 2014, v. 31, n. 3, p. 364, doi. 10.14573/altex.1405151
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- Publication type:
- Article
Identifying and Quantifying Heterogeneity in High Content Analysis: Application of Heterogeneity Indices to Drug Discovery.
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- PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0102678
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- Article
Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans.
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- Stem Cell Research & Therapy, 2013, v. 4, p. 1, doi. 10.1186/scrt377
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- Publication type:
- Article
Characterization and Optimization of a Novel Protein–Protein Interaction Biosensor High-Content Screening Assay to Identify Disruptors of the Interactions Between p53 and hDM2.
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- Assay & Drug Development Technologies, 2010, v. 8, n. 4, p. 437, doi. 10.1089/adt.2010.0281
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- Article
Systems Cell Biology Knowledge Created fromHigh Content Screening.
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- Assay & Drug Development Technologies, 2005, v. 3, n. 5, p. 501
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- Article
Advances in High Content Screening for Drug Discovery.
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- Assay & Drug Development Technologies, 2003, v. 1, n. 4, p. 565
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- Article
Traction forces of cytokinesis measured with optically modified elastic substrata.
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- Nature, 1997, v. 385, n. 6615, p. 450, doi. 10.1038/385450a0
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- Article
Potential of Machine-Vision Light Microscopy in Toxicologic Pathology.
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- Toxicologic Pathology, 1994, v. 22, n. 2, p. 145, doi. 10.1177/019262339402200208
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- Article
Heterogeneity of the changes in cytoplasmic pH upon serum stimulation of quiescent fibroblasts.
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- Journal of Cellular Physiology, 1989, v. 141, n. 2, p. 410, doi. 10.1002/jcp.1041410223
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- Article
In Memoriam Robert Day Allen (1927-1986).
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- Annals of the New York Academy of Sciences, 1986, v. 483, n. 1, p. xi, doi. 10.1111/j.1749-6632.1986.tb34484.x
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- Article
Robert Day Allen (1927-1986).
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- Nature, 1986, v. 321, n. 6071, p. 647, doi. 10.1038/321647a0
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- Article
Methods for the measurement of polarization optical properties: I. Birefringence.
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- Journal of Microscopy, 1976, v. 108, n. 3, p. 251, doi. 10.1111/j.1365-2818.1976.tb01097.x
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- Article