Works by Tautz, Lutz

Results: 14

Inhibitor of the Tyrosine Phosphatase STEP Reverses Cognitive Deficits in a Mouse Model of Alzheimer's Disease.

Published in:

PLoS Biology, 2014, v. 12, n. 8, p. 1, doi. 10.1371/journal.pbio.1001923

By:

Xu, Jian;
Chatterjee, Manavi;
Baguley, Tyler D.;
Brouillette, Jonathan;
Kurup, Pradeep;
Ghosh, Debolina;
Kanyo, Jean;
Zhang, Yang;
Seyb, Kathleen;
Ononenyi, Chimezie;
Foscue, Ethan;
Anderson, George M.;
Gresack, Jodi;
Cuny, Gregory D.;
Glicksman, Marcie A.;
Greengard, Paul;
Lam, TuKiet T.;
Tautz, Lutz;
Nairn, Angus C.;
Ellman, Jonathan A.

Publication type:

Article

Enzyme mechanistic studies of NMA1982, a protein tyrosine phosphatase and potential virulence factor in Neisseria meningitidis.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-49561-9

By:

Wu, Shuangding;
Coureuil, Mathieu;
Nassif, Xavier;
Tautz, Lutz

Publication type:

Article

Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant.

Published in:

Nature Genetics, 2005, v. 37, n. 12, p. 1317, doi. 10.1038/ng1673

By:

Vang, Torkel;
Congia, Mauro;
Macis, Maria Doloretta;
Musumeci, Lucia;
Orrú, Valeria;
Zavattari, Patrizia;
Nika, Konstantina;
Tautz, Lutz;
Taskén, Kjetil;
Cucca, Francesco;
Mustelin, Tomas;
Bottini, Nunzio

Publication type:

Article

In Silico Screening for PTPN22 Inhibitors: Active Hits from an Inactive Phosphatase Conformation.

Published in:

ChemMedChem, 2009, v. 4, n. 3, p. 440, doi. 10.1002/cmdc.200800375

By:

Wu, Shuangding;
Bottini, Massimo;
Rickert, Robert C.;
Mustelin, Tomas;
Tautz, Lutz

Publication type:

Article

Cervix carcinoma is associated with an up-regulation and nuclear localization of the dual-specificity protein phosphatase VHR.

Published in:

BMC Cancer, 2008, v. 8, p. 1, doi. 10.1186/1471-2407-8-147

By:

Henkens, Rachel;
Delvenne, Philippe;
Arafa, Mohammad;
Moutschen, Michel;
Zeddou, Mustapha;
Tautz, Lutz;
Boniver, Jacques;
Mustelin, Tomas;
Rahmouni, Souad

Publication type:

Article

Development of a Robust High-Throughput Screening Platform for Inhibitors of the Striatal-Enriched Tyrosine Phosphatase (STEP).

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4417, doi. 10.3390/ijms22094417

By:

Lambert, Lester J;
Grotegut, Stefan;
Celeridad, Maria;
Gosalia, Palak;
Backer, Laurent JS De;
Bobkov, Andrey A;
Salaniwal, Sumeet;
Chung, Thomas DY;
Zeng, Fu-Yue;
Pass, Ian;
Lombroso, Paul J;
Cosford, Nicholas DP;
Tautz, Lutz;
Ciruela, Francisco

Publication type:

Article

Distinct functional and conformational states of the human lymphoid tyrosine phosphatase catalytic domain can be targeted by choice of the inhibitor chemotype.

Published in:

Journal of Computer-Aided Molecular Design, 2011, v. 25, n. 9, p. 873, doi. 10.1007/s10822-011-9469-2

By:

Vidović, Dušica;
Xie, Yuli;
Rinderspacher, Alison;
Deng, Shi-Xian;
Landry, Donald;
Chung, Caty;
Smith, Deborah;
Tautz, Lutz;
Schürer, Stephan

Publication type:

Article

A Conserved Mechanism for Control of Human and Mouse Embryonic Stem Cell Pluripotency and Differentiation by Shp2 Tyrosine Phosphatase.

Published in:

PLoS ONE, 2009, v. 4, n. 3, p. 1, doi. 10.1371/journal.pone.0004914

By:

Dongmei Wu;
Yuhong Pang;
Yuehai Ke;
Jianxiu Yu;
Zhao He;
Tautz, Lutz;
Mustelin, Tomas;
Sheng Ding;
Ziwei Huang;
Gen-Sheng Feng

Publication type:

Article

Crystal structure of NMA1982 from Neisseria meningitidis at 1.5 Å resolution provides a structural scaffold for nonclassical, eukaryotic-like phosphatases.

Published in:

Proteins, 2007, v. 69, n. 2, p. 415, doi. 10.1002/prot.21314

By:

Krishna, S. Sri;
Tautz, Lutz;
Xu, Qingping;
McMullan, Daniel;
Miller, Mitchell D.;
Abdubek, Polat;
Ambing, Eileen;
Astakhova, Tamara;
Axelrod, Herbert L.;
Carlton, Dennis;
Chiu, Hsiu-Ju;
Clayton, Thomas;
DiDonato, Michael;
Duan, Lian;
Elsliger, Marc-André;
Grzechnik, Slawomir K.;
Hale, Joanna;
Hampton, Eric;
Han, Gye Won;
Haugen, Justin

Publication type:

Article

Discovery and Characterization Small Molecule Modulators of Striatal‐Enriched Protein Tyrosine Phosphatase (STEP) for Alzheimer's Disease Therapeutics.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S6, p. 1, doi. 10.1002/alz.083572

By:

Wu, Jiaqian;
Han, Ye Na;
Cosford, Nicholas;
Tautz, Lutz

Publication type:

Article

Identification and characterization of DUSP27, a novel dual-specific protein phosphatase

Published in:

FEBS Letters, 2007, v. 581, n. 13, p. 2527, doi. 10.1016/j.febslet.2007.04.059

By:

Friedberg, Ilan;
Nika, Konstantina;
Tautz, Lutz;
Saito, Kan;
Cerignoli, Fabio;
Friedberg, Iddo;
Godzik, Adam;
Mustelin, Tomas

Publication type:

Article

LYP inhibits T-cell activation when dissociated from CSK.

Published in:

Nature Chemical Biology, 2012, v. 8, n. 5, p. 437, doi. 10.1038/nchembio.916

By:

Vang, Torkel;
Liu, Wallace H;
Delacroix, Laurence;
Wu, Shuangding;
Vasile, Stefan;
Dahl, Russell;
Yang, Li;
Musumeci, Lucia;
Francis, Dana;
Landskron, Johannes;
Tasken, Kjetil;
Tremblay, Michel L;
Lie, Benedicte A;
Page, Rebecca;
Mustelin, Tomas;
Rahmouni, Souad;
Rickert, Robert C;
Tautz, Lutz

Publication type:

Article

Lipid Raft Targeting of Hematopoietic Protein Tyrosine Phosphatase by Protein Kinase C θ-Mediated Phosphorylation.

Published in:

Molecular & Cellular Biology, 2006, v. 26, n. 5, p. 21, doi. 10.1128/MCB.26.5.1806-1816.2006

By:

Nika, Konstantina;
Charvet, Céline;
Williams, Scott;
Tautz, Lutz;
Bruckner, Shane;
Rahmouni, Souad;
Bottini, Nunzio;
Schoenberger, Stephen P.;
Baier, Gottfried;
Altman, Amnon;
Mustelin, Tomas

Publication type:

Article

PTP1B: a new therapeutic target for Rett syndrome.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 8, p. 2931, doi. 10.1172/JCI83192

By:

Tautz, Lutz

Publication type:

Article