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Enzyme mechanistic studies of NMA1982, a protein tyrosine phosphatase and potential virulence factor in Neisseria meningitidis.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-49561-9
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- Article
Development of a Robust High-Throughput Screening Platform for Inhibitors of the Striatal-Enriched Tyrosine Phosphatase (STEP).
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- International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4417, doi. 10.3390/ijms22094417
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- Article
PTP1B: a new therapeutic target for Rett syndrome.
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- Journal of Clinical Investigation, 2015, v. 125, n. 8, p. 2931, doi. 10.1172/JCI83192
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- Article
Inhibitor of the Tyrosine Phosphatase STEP Reverses Cognitive Deficits in a Mouse Model of Alzheimer's Disease.
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- PLoS Biology, 2014, v. 12, n. 8, p. 1, doi. 10.1371/journal.pbio.1001923
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- Article
LYP inhibits T-cell activation when dissociated from CSK.
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- Nature Chemical Biology, 2012, v. 8, n. 5, p. 437, doi. 10.1038/nchembio.916
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- Article
Distinct functional and conformational states of the human lymphoid tyrosine phosphatase catalytic domain can be targeted by choice of the inhibitor chemotype.
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- Journal of Computer-Aided Molecular Design, 2011, v. 25, n. 9, p. 873, doi. 10.1007/s10822-011-9469-2
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- Article
In Silico Screening for PTPN22 Inhibitors: Active Hits from an Inactive Phosphatase Conformation.
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- ChemMedChem, 2009, v. 4, n. 3, p. 440, doi. 10.1002/cmdc.200800375
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- Article
A Conserved Mechanism for Control of Human and Mouse Embryonic Stem Cell Pluripotency and Differentiation by Shp2 Tyrosine Phosphatase.
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- PLoS ONE, 2009, v. 4, n. 3, p. 1, doi. 10.1371/journal.pone.0004914
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- Article
Cervix carcinoma is associated with an up-regulation and nuclear localization of the dual-specificity protein phosphatase VHR.
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- BMC Cancer, 2008, v. 8, p. 1, doi. 10.1186/1471-2407-8-147
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- Article
Crystal structure of NMA1982 from Neisseria meningitidis at 1.5 Å resolution provides a structural scaffold for nonclassical, eukaryotic-like phosphatases.
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- Proteins, 2007, v. 69, n. 2, p. 415, doi. 10.1002/prot.21314
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- Article
Identification and characterization of DUSP27, a novel dual-specific protein phosphatase
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- FEBS Letters, 2007, v. 581, n. 13, p. 2527, doi. 10.1016/j.febslet.2007.04.059
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- Article
Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant.
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- Nature Genetics, 2005, v. 37, n. 12, p. 1317, doi. 10.1038/ng1673
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- Article