Works by Targher, Giovanni

Results: 257

Nonalcoholic fatty liver disease: cause or consequence of type 2 diabetes?

Published in:

Liver International, 2016, v. 36, n. 11, p. 1563, doi. 10.1111/liv.13185

By:

Valenti, Luca;
Bugianesi, Elisabetta;
Pajvani, Utpal;
Targher, Giovanni

Publication type:

Article

Bilirubin concentration and cardiovascular risk profile.

Published in:

2009

By:

Lippi, Giuseppe;
Targher, Giovanni;
Montagnana, Martina;
Salvagno, Gian Luca;
Guidi, Gian Cesare

Publication type:

Letter

Prevalence of Non-Alcoholic Fatty Liver Disease in Adult Individuals with Moderate-to-Severe Atopic Dermatitis.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 18, p. 6057, doi. 10.3390/jcm12186057

By:

Maurelli, Martina;
Gisondi, Paolo;
Bellinato, Francesco;
Mantovani, Alessandro;
Targher, Giovanni;
Girolomoni, Giampiero

Publication type:

Article

Subclinical Myocardial Fibrosis in Systemic Lupus Erythematosus as Assessed by Pulse-Cancellation Echocardiography: A Pilot Study.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 16, p. 4788, doi. 10.3390/jcm11164788

By:

Giollo, Alessandro;
Vinco, Giulia;
Cioffi, Giovanni;
Frizzera, Francesca;
Quinternetto, Anna;
Bergamini, Corinna;
Dal Porto, Marta;
Orsolini, Giovanni;
Zen, Margherita;
Doria, Andrea;
Gatti, Davide;
Ribichini, Flavio Luciano;
Targher, Giovanni;
Rossini, Maurizio;
Viapiana, Ombretta

Publication type:

Article

Metabolic dysfunction‐associated steatotic liver disease, insulin sensitivity and continuous glucose monitoring metrics in patients with type 1 diabetes: A multi‐centre cross‐sectional study.

Published in:

Diabetes, Obesity & Metabolism, 2025, v. 27, n. 6, p. 3201, doi. 10.1111/dom.16333

By:

Vergani, Michela;
Borella, Nicolò Diego;
Rizzo, Mariangela;
Conti, Matteo;
Perra, Silvia;
Bianconi, Eleonora;
Sani, Elena;
Csermely, Alessandro;
Grespan, Elisabetta;
Targher, Giovanni;
Perseghin, Gianluca;
Mantovani, Alessandro;
Ciardullo, Stefano

Publication type:

Article

Hepatic thyroid hormone receptor‐β signalling: Mechanisms and recent advancements in the treatment of metabolic dysfunction‐associated steatohepatitis.

Published in:

2025

By:

Polyzos, Stergios A.;
Targher, Giovanni

Publication type:

Literature Review

Ceramide‐based risk score CERT‐1 improves risk prediction for overall mortality and adverse cardiovascular outcomes in patients with and without cardiovascular disease: A prospective cohort study.

Published in:

Diabetes, Obesity & Metabolism, 2025, v. 27, n. 3, p. 1488, doi. 10.1111/dom.16156

By:

Mantovani, Alessandro;
Lunardi, Gianluigi;
Bonapace, Stefano;
Molinero, Agustin E.;
Morandin, Riccardo;
Fiorio, Veronica;
Molon, Giulio;
Byrne, Christopher D.;
Targher, Giovanni

Publication type:

Article

Hepatic lipogenesis marked by GCKR‐modulated triglycerides increases serum FGF21 in children/teens with obesity.

Published in:

Diabetes, Obesity & Metabolism, 2025, v. 27, n. 2, p. 825, doi. 10.1111/dom.16081

By:

Maffeis, Claudio;
Morandi, Anita;
Zusi, Chiara;
Olivieri, Francesca;
Fornari, Elena;
Cavarzere, Paolo;
Piona, Claudia;
Corradi, Massimiliano;
Emiliani, Federica;
Da Ros, Alessandro;
Berni Canani, Roberto;
Mantovani, Alessandro;
Targher, Giovanni

Publication type:

Article

Glycaemic control metrics and metabolic dysfunction–associated steatotic liver disease in children and adolescents with type 1 diabetes.

Published in:

Diabetes, Obesity & Metabolism, 2024, v. 26, n. 12, p. 5896, doi. 10.1111/dom.15961

By:

Maffeis, Claudio;
Piona, Claudia;
Morandi, Anita;
Marigliano, Marco;
Morotti, Elisa;
Mancioppi, Valentina;
Caiazza, Erika;
Zusi, Chiara;
Emiliani, Federica;
Mantovani, Alessandro;
Colecchia, Antonio;
Targher, Giovanni

Publication type:

Article

Associations between cuprotosis‐related genes and the spectrum of metabolic dysfunction‐associated fatty liver disease: An exploratory study.

Published in:

Diabetes, Obesity & Metabolism, 2024, v. 26, n. 12, p. 5757, doi. 10.1111/dom.15946

By:

Yuan, Hai‐Yang;
Liu, Wen‐Yue;
Feng, Gong;
Chen, Sui‐Dan;
Jin, Xin‐Zhe;
Chen, Li‐Li;
Song, Zi‐Jun;
Li, Ke;
Byrne, Christopher D.;
Targher, Giovanni;
Tian, Na;
Li, Gang;
Zhang, Xin‐Lei;
George, Jacob;
Zhou, Meng;
Wang, Fudi;
Zheng, Ming‐Hua

Publication type:

Article

Causal relationship between key genes and metabolic dysfunction‐associated fatty liver disease risk mediated by immune cells: A Mendelian randomization and mediation analysis.

Published in:

Diabetes, Obesity & Metabolism, 2024, v. 26, n. 12, p. 5590, doi. 10.1111/dom.15925

By:

Feng, Gong;
He, Na;
Gao, Jing;
Li, Xiao‐Cheng;
Zhang, Fen‐Na;
Liu, Cheng‐Cheng;
Targher, Giovanni;
Byrne, Christopher D.;
Mi, Man;
Zheng, Ming‐Hua;
Ye, Feng

Publication type:

Article

Serum bile acid profiles are associated with heart failure with preserved ejection fraction in patients with metabolic dysfunction‐associated fatty liver disease: An exploratory study.

Published in:

Diabetes, Obesity & Metabolism, 2024, v. 26, n. 9, p. 3684, doi. 10.1111/dom.15709

By:

Zhou, Xiao‐Dong;
Xu, Cui‐Fang;
Chen, Qin‐Fen;
Shapiro, Michael D.;
Lip, Gregory Y. H.;
Chen, Li‐Li;
Targher, Giovanni;
Byrne, Christopher D.;
Tian, Na;
Xiao, Tie;
Huang, Chen‐Xiao;
Ni, Yan;
Zheng, Ming‐Hua

Publication type:

Article

Effects of glucose‐lowering agents on cardiovascular and renal outcomes in subjects with type 2 diabetes: An updated meta‐analysis of randomized controlled trials with external adjudication of events.

Published in:

Diabetes, Obesity & Metabolism, 2023, v. 25, n. 2, p. 444, doi. 10.1111/dom.14888

By:

Mannucci, Edoardo;
Gallo, Marco;
Giaccari, Andrea;
Candido, Riccardo;
Pintaudi, Basilio;
Targher, Giovanni;
Monami, Matteo

Publication type:

Article

Non‐alcoholic fatty liver disease‐related risk of cardiovascular disease and other cardiac complications.

Published in:

Diabetes, Obesity & Metabolism, 2022, v. 24, p. 28, doi. 10.1111/dom.14484

By:

Byrne, Christopher D.;
Targher, Giovanni

Publication type:

Article

Abnormal liver enzymes in children and infants with COVID‐19: A narrative review of case‐series studies.

Published in:

2020

By:

Zhou, Yong‐Hai;
Zheng, Kenneth I.;
Targher, Giovanni;
Byrne, Christopher D.;
Zheng, Ming‐Hua

Publication type:

Letter to the Editor

Letter: Drug interaction in resmetirom times.

Published in:

Alimentary Pharmacology & Therapeutics, 2024, v. 60, n. 4, p. 533, doi. 10.1111/apt.18062

By:

Zhou, Xiao‐Dong;
Liu, Wen‐Yue;
Targher, Giovanni;
Byrne, Christopher D.;
Zheng, Ming‐Hua

Publication type:

Article

Stereotactic body radiotherapy for lung oligometastases impacts on systemic treatment-free survival: a cohort study.

Published in:

2018

By:

Mazzola, Rosario;
Fersino, Sergio;
Ferrera, Giuseppe;
Targher, Giovanni;
Figlia, Vanessa;
Triggiani, Luca;
Pasinetti, Nadia;
Lo Casto, Antonio;
Ruggieri, Ruggero;
Magrini, Stefano Maria;
Alongi, Filippo

Publication type:

journal article

Inter-atrial shunt inversion by the sitting position in a patient with a patent foramen ovale and acute pulmonary embolism.

Published in:

European Heart Journal, 2014, v. 35, n. 16, p. 1032, doi. 10.1093/eurheartj/ehu018

By:

Valbusa, Filippo;
Bonapace, Stefano;
Lanzoni, Laura;
Tubaro, Alessandro;
Delaini, Carlo;
Barbieri, Enrico;
Targher, Giovanni;
Arcaro, Guido

Publication type:

Article

Mortality From Chronic Liver Diseases in Diabetes.

Published in:

American Journal of Gastroenterology (Springer Nature), 2014, v. 109, n. 7, p. 1020, doi. 10.1038/ajg.2014.132

By:

Zoppini, Giacomo;
Fedeli, Ugo;
Gennaro, Nicola;
Saugo, Mario;
Targher, Giovanni;
Bonora, Enzo

Publication type:

Article

Non-alcoholic fatty liver disease is associated with an increased prevalence of atrial fibrillation in hospitalized patients with Type 2 diabetes.

Published in:

Clinical Science, 2013, v. 125, n. 6, p. 301, doi. 10.1042/CS20130036

By:

TARGHER, Giovanni;
MANTOVANI, Alessandro;
PICHIRI, Isabella;
RIGOLON, Riccardo;
DAURIZ, Marco;
ZOPPINI, Giacomo;
MORANI, Giovanni;
VASSANELLI, Corrado;
BONORA, Enzo

Publication type:

Article

Metabolic dysfunction-associated fatty liver disease and implications for cardiovascular risk and disease prevention.

Published in:

Cardiovascular Diabetology, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12933-022-01697-0

By:

Zhou, Xiao-Dong;
Cai, Jingjing;
Targher, Giovanni;
Byrne, Christopher D.;
Shapiro, Michael D.;
Sung, Ki-Chul;
Somers, Virend K.;
Chahal, C. Anwar A.;
George, Jacob;
Chen, Li-Li;
Zhou, Yong;
Zheng, Ming-Hua

Publication type:

Article

The hepato-ovarian axis: genetic evidence for a causal association between non-alcoholic fatty liver disease and polycystic ovary syndrome.

Published in:

BMC Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12916-023-02775-0

By:

Liu, Dong;
Gao, Xue;
Pan, Xiong-Fei;
Zhou, Tao;
Zhu, Cairong;
Li, Fei;
Fan, Jian-Gao;
Targher, Giovanni;
Zhao, Jian

Publication type:

Article

Association of inflammation with anaemia in patients with chronic kidney disease not requiring chronic dialysis.

Published in:

Nephrology Dialysis Transplantation, 2008, v. 23, n. 9, p. 2879, doi. 10.1093/ndt/gfn109

By:

Michel Chonchol;
Giuseppe Lippi;
Martina Montagnana;
Michele Muggeo;
Giovanni Targher

Publication type:

Article

Association between 25-hydroxyvitamin D deficiency and cardiovascular disease in type 2 diabetic patients with mild kidney dysfunction.

Published in:

Nephrology Dialysis Transplantation, 2008, v. 23, n. 1, p. 269

By:

Michel Chonchol;
Massimo Cigolini;
Giovanni Targher

Publication type:

Article

Hyperthyroidism and Venous Thrombosis: A Casual or Causal Association? A Systematic Literature Review.

Published in:

Clinical & Applied Thrombosis/Hemostasis, 2011, v. 17, n. 4, p. 387, doi. 10.1177/1076029610364521

By:

Franchini, Massimo;
Lippi, Giuseppe;
Targher, Giovanni

Publication type:

Article

Subclinical Acute Kidney Injury in COVID-19 Patients: A Retrospective Cohort Study.

Published in:

2020

By:

Sun, Dan-Qin;
Wang, Ting-Yao;
Zheng, Kenneth I.;
Targher, Giovanni;
Byrne, Christopher D.;
Chen, Yong-Ping;
Zheng, Ming-Hua

Publication type:

Letter

Adiponectin and migraine: systematic review of clinical evidence.

Published in:

Neurological Sciences, 2014, v. 35, n. 8, p. 1167, doi. 10.1007/s10072-014-1719-3

By:

Lippi, Giuseppe;
Meschi, Tiziana;
Mattiuzzi, Camilla;
Borghi, Loris;
Targher, Giovanni

Publication type:

Article

Bioactive metabolites: A clue to the link between MASLD and CKD?

Published in:

Clinical & Molecular Hepatology, 2025, v. 31, n. 1, p. 56, doi. 10.3350/cmh.2024.0782

By:

Wen-Ying Chen;
Jia-Hui Zhang;
Li-Li Chen;
Byrne, Christopher D.;
Targher, Giovanni;
Liang Luo;
Yan Ni;
Ming-Hua Zheng;
Dan-Qin Sun

Publication type:

Article

Old and new classes of glucose-lowering agents as treatments for non-alcoholic fatty liver disease: A narrative review.

Published in:

Clinical & Molecular Hepatology, 2022, v. 28, n. 4, p. 725, doi. 10.3350/cmh.2022.0015

By:

Lei Miao;
Jing Xu;
Targher, Giovanni;
Byrne, Christopher D.;
Ming-Hua Zheng

Publication type:

Article

Editorial: Resmetirom – a promising treatment option for NASH and liver fibrosis.

Published in:

2024

By:

Targher, Giovanni

Publication type:

Editorial

Editorial: Recent advances in fibrosis assessment for metabolic dysfunction‐associated fatty liver disease–Authors' reply.

Published in:

2023

By:

Gao, Feng;
Byrne, Christopher D.;
Targher, Giovanni;
Zhuo, Shuangmu;
Zheng, Ming‐Hua

Publication type:

Editorial

AutoFibroNet: A deep learning and multi‐photon microscopy‐derived automated network for liver fibrosis quantification in MAFLD.

Published in:

Alimentary Pharmacology & Therapeutics, 2023, v. 58, n. 6, p. 573, doi. 10.1111/apt.17635

By:

Zhan, Huiling;
Chen, Siyu;
Gao, Feng;
Wang, Guangxing;
Chen, Sui‐Dan;
Xi, Gangqin;
Yuan, Hai‐Yang;
Li, Xiaolu;
Liu, Wen‐Yue;
Byrne, Christopher D.;
Targher, Giovanni;
Chen, Miao‐Yang;
Yang, Yong‐Feng;
Chen, Jun;
Fan, Zhiwen;
Sun, Xitai;
Cai, Guorong;
Zheng, Ming‐Hua;
Zhuo, Shuangmu

Publication type:

Article

Featured Cover.

Published in:

Alimentary Pharmacology & Therapeutics, 2023, v. 58, n. 6, p. i, doi. 10.1111/apt.17024

By:

Zhan, Huiling;
Chen, Siyu;
Gao, Feng;
Wang, Guangxing;
Chen, Sui‐Dan;
Xi, Gangqin;
Yuan, Hai‐Yang;
Li, Xiaolu;
Liu, Wen‐Yue;
Byrne, Christopher D.;
Targher, Giovanni;
Chen, Miao‐Yang;
Yang, Yong‐Feng;
Chen, Jun;
Fan, Zhiwen;
Sun, Xitai;
Cai, Guorong;
Zheng, Ming‐Hua;
Zhuo, Shuangmu

Publication type:

Article

Adverse effect of PNPLA3 p.I148M genetic variant on kidney function in middle-aged individuals with metabolic dysfunction.

Published in:

Alimentary Pharmacology & Therapeutics, 2023, v. 57, n. 10, p. 1093, doi. 10.1111/apt.17477

By:

Mantovani, Alessandroq;
Pelusi, Serena;
Margarita, Sara;
Malvestiti, Francesco;
Dell'Alma, Michela;
Bianco, Cristiana;
Ronzoni, Luisa;
Prati, Daniele;
Targher, Giovanni;
Valenti, Luca

Publication type:

Article

Secondary bile acids improve risk prediction for non‐invasive identification of mild liver fibrosis in nonalcoholic fatty liver disease.

Published in:

Alimentary Pharmacology & Therapeutics, 2023, v. 57, n. 8, p. 872, doi. 10.1111/apt.17362

By:

Liu, A‐Na;
Xu, Cui‐Fang;
Liu, Ya‐Ru;
Sun, Dan‐Qin;
Jiang, Ling;
Tang, Liang‐Jie;
Zhu, Pei‐Wu;
Chen, Sui‐Dan;
Liu, Wen‐Yue;
Wang, Xiao‐Dong;
Targher, Giovanni;
Byrne, Christopher D.;
Wong, Vincent Wai‐Sun;
Fu, Junfen;
Su, Ming‐Ming;
Loomba, Rohit;
Zheng, Ming‐Hua;
Ni, Yan

Publication type:

Article

Editorial: higher levels of certain serum bile acids in non‐alcoholic fatty liver disease—new insights from Guatemala.

Published in:

2022

By:

Mantovani, Alessandro;
Targher, Giovanni

Publication type:

Editorial

Editorial: a diabetologist's perspective on the diagnosis and monitoring of NAFLD.

Published in:

Alimentary Pharmacology & Therapeutics, 2020, v. 52, n. 4, p. 710, doi. 10.1111/apt.15906

By:

Targher, Giovanni

Publication type:

Article

Editorial: importance of an elevated mean platelet volume for prediction of major adverse cardiovascular events in non‐alcoholic fatty liver disease.

Published in:

2019

By:

Targher, Giovanni;
Lippi, Giuseppe

Publication type:

Editorial

Letter: non‐alcoholic fatty liver disease is associated with a history of osteoporotic fractures but not with low bone mineral density—authors' reply.

Published in:

Alimentary Pharmacology & Therapeutics, 2019, v. 49, n. 7, p. 961, doi. 10.1111/apt.15181

By:

Targher, Giovanni;
Mantovani, Alessandro;
Dauriz, Marco;
Bonnet, Fabrice;
Byrne, Christopher D.

Publication type:

Article

Systematic review with meta‐analysis: non‐alcoholic fatty liver disease is associated with a history of osteoporotic fractures but not with low bone mineral density.

Published in:

Alimentary Pharmacology & Therapeutics, 2019, v. 49, n. 4, p. 375, doi. 10.1111/apt.15087

By:

Mantovani, Alessandro;
Dauriz, Marco;
Gatti, Davide;
Viapiana, Ombretta;
Zoppini, Giacomo;
Lippi, Giuseppe;
Byrne, Christopher D.;
Bonnet, Fabrice;
Bonora, Enzo;
Targher, Giovanni

Publication type:

Article

Lifestyle Interventions for Non-Obese Patients Both with, and at Risk, of Non-Alcoholic Fatty Liver Disease.

Published in:

Diabetes & Metabolism Journal, 2022, v. 46, n. 3, p. 391, doi. 10.4093/dmj.2022.0048

By:

Xin-Lei Zhang;
Ting-Yao Wang;
Targher, Giovanni;
Byrne, Christopher D.;
Ming-Hua Zheng

Publication type:

Article

Machine learning algorithm outperforms fibrosis markers in predicting significant fibrosis in biopsy‐confirmed NAFLD.

Published in:

Journal of Hepato -- Biliary -- Pancreatic Sciences, 2021, v. 28, n. 7, p. 593, doi. 10.1002/jhbp.972

By:

Feng, Gong;
Zheng, Kenneth I.;
Li, Yang‐Yang;
Rios, Rafael S.;
Zhu, Pei‐Wu;
Pan, Xiao‐Yan;
Li, Gang;
Ma, Hong‐Lei;
Tang, Liang‐Jie;
Byrne, Christopher D.;
Targher, Giovanni;
He, Na;
Mi, Man;
Chen, Yong‐Ping;
Zheng, Ming‐Hua

Publication type:

Article

Further advices on measuring lipoprotein(a) for reducing the residual cardiovascular risk on statin therapy.

Published in:

Clinical Chemistry & Laboratory Medicine, 2020, v. 58, n. 8, p. e144, doi. 10.1515/cclm-2020-0076

By:

Lippi, Giuseppe;
Targher, Giovanni

Publication type:

Article

Influence of hypertriglyceridemia, hyperbilirubinemia and hemolysis on thrombin generation in human plasma.

Published in:

Clinical Chemistry & Laboratory Medicine, 2019, v. 57, n. 11, p. 1784, doi. 10.1515/cclm-2019-0135

By:

Salvagno, Gian Luca;
Favaloro, Emmanuel J.;
Demonte, Davide;
Gelati, Matteo;
Poli, Giovanni;
Targher, Giovanni;
Lippi, Giuseppe

Publication type:

Article

Further insights on the relationship between bilirubin and C-reactive protein.

Published in:

Clinical Chemistry & Laboratory Medicine, 2012, v. 50, n. 12, p. 2229, doi. 10.1515/cclm-2012-0343

By:

Lippi, Giuseppe;
Targher, Giovanni

Publication type:

Article

Relationship of hepatic steatosis and alanine aminotransferase with coronary calcification.

Published in:

Clinical Chemistry & Laboratory Medicine, 2011, v. 49, n. 4, p. 741, doi. 10.1515/CCLM.2011.104

By:

Targher, Giovanni

Publication type:

Article

Glycated hemoglobin (HbA1c): old dogmas, a new perspective?

Published in:

Clinical Chemistry & Laboratory Medicine, 2010, v. 48, n. 5, p. 609, doi. 10.1515/CCLM.2010.144

By:

Lippi, Giuseppe;
Targher, Giovanni

Publication type:

Article

Elevated serum γ-glutamyltransferase activity is associated with increased risk of mortality, incident type 2 diabetes, cardiovascular events, chronic kidney disease and cancer – a narrative review.

Published in:

Clinical Chemistry & Laboratory Medicine, 2010, v. 48, n. 2, p. 147, doi. 10.1515/CCLM.2010.031

By:

Targher, Giovanni

Publication type:

Article

Prevalence of thyroid autoimmunity and subclinical hypothyroidism in persons with chronic kidney disease not requiring chronic dialysis.

Published in:

Clinical Chemistry & Laboratory Medicine, 2009, v. 47, n. 11, p. 1367, doi. 10.1515/CCLM.2009.304

By:

Targher, Giovanni;
Chonchol, Michel;
Zoppini, Giacomo;
Salvagno, Gianluca;
Pichiri, Isabella;
Franchini, Massimo;
Lippi, Giuseppe

Publication type:

Article

Genetic and biochemical heterogeneity of cardiac troponins: clinical and laboratory implications.

Published in:

Clinical Chemistry & Laboratory Medicine, 2009, v. 47, n. 10, p. 1183, doi. 10.1515/CCLM.2009.322

By:

Lippi, Giuseppe;
Targher, Giovanni;
Franchini, Massimo;
Plebani, Mario

Publication type:

Article