Works by Tarasov, Andrei I.

Results: 30

Comparative Effects of GLP-1 and GLP-2 on Beta-Cell Function, Glucose Homeostasis and Appetite Regulation.
Published in:
Biomolecules (2218-273X), 2024, v. 14, n. 12, p. 1520, doi. 10.3390/biom14121520
By:
- Ali, Asif;
- Khan, Dawood;
- Dubey, Vaibhav;
- Tarasov, Andrei I.;
- Flatt, Peter R.;
- Irwin, Nigel
Publication type:
Article
Cafeteria diet compromises natural adaptations of islet cell transdifferentiation and turnover in pregnancy.
Published in:
Diabetic Medicine, 2025, v. 42, n. 1, p. 1, doi. 10.1111/dme.15434
By:
- Dubey, Vaibhav;
- Tanday, Neil;
- Irwin, Nigel;
- Tarasov, Andrei I.;
- Flatt, Peter R.;
- Moffett, R. Charlotte
Publication type:
Article
Liver glycogen phosphorylase is upregulated in glioblastoma and provides a metabolic vulnerability to high dose radiation.
Published in:
Cell Death & Disease, 2022, v. 13, n. 6, p. 1, doi. 10.1038/s41419-022-05005-2
By:
- Zois, Christos E.;
- Hendriks, Anne M.;
- Haider, Syed;
- Pires, Elisabete;
- Bridges, Esther;
- Kalamida, Dimitra;
- Voukantsis, Dimitrios;
- Lagerholm, B. Christoffer;
- Fehrmann, Rudolf S. N.;
- den Dunnen, Wilfred F. A.;
- Tarasov, Andrei I.;
- Baba, Otto;
- Morris, John;
- Buffa, Francesca M.;
- McCullagh, James S. O.;
- Jalving, Mathilde;
- Harris, Adrian L.
Publication type:
Article
[P3]PP, a stable, long‐acting pancreatic polypeptide analogue, evokes weight lowering and pancreatic beta‐cell‐protective effects in obesity‐associated diabetes.
Published in:
Diabetes, Obesity & Metabolism, 2024, v. 26, n. 11, p. 4945, doi. 10.1111/dom.15897
By:
- Tanday, Neil;
- Zhu, Wuyun;
- Tarasov, Andrei I.;
- Flatt, Peter R.;
- Irwin, Nigel
Publication type:
Article
Pancreatic islet cell plasticity: Pathogenic or therapeutically exploitable?
Published in:
Diabetes, Obesity & Metabolism, 2024, v. 26, n. 1, p. 16, doi. 10.1111/dom.15300
By:
- Tanday, Neil;
- Tarasov, Andrei I.;
- Moffett, R. Charlotte;
- Flatt, Peter R.;
- Irwin, Nigel
Publication type:
Article
Identification of the PIP2-binding site on Kir6.2 by molecular modelling and functional analysis.
Published in:
EMBO Journal, 2007, v. 26, n. 16, p. 3749, doi. 10.1038/sj.emboj.7601809
By:
- Haider, Shozeb;
- Tarasov, Andrei I.;
- Craig, Tim J.;
- Sansom, Mark S. P.;
- Ashcroft, Frances M
Publication type:
Article
Insulin Gene Mutations Resulting in Early-Onset Diabetes: Marked Differences in Clinical Presentation, Metabolic Status, and Pathogenic Effect Through Endoplasmic Reticulum Retention.
Published in:
Diabetes, 2010, v. 59, n. 3, p. 653, doi. 10.2337/db09-1091
By:
- Meur, Gargi;
- Simon, Albane;
- Harun, Nasret;
- Virally, Marie;
- Dechaume, Aurélie;
- Bonnefond, Amélie;
- Fetita, Sabrina;
- Tarasov, Andrei I.;
- Guillausseau, Pierre-Jean;
- Boesgaard, Trine Welløv;
- Pedersen, Oluf;
- Hansen, Torben;
- Polak, Michel;
- Gautier, Jean-Francois;
- Froguel, Philippe;
- Rutter, Guy A.;
- Vaxillaire, Martine
Publication type:
Article
Insulin Storage and Glucose Homeostasis in Mice Null for the Granule Zinc Transporter ZnT8 and Studies of the Type 2 Diabetes-Associated Variants.
Published in:
Diabetes, 2009, v. 58, n. 9, p. 2070, doi. 10.2337/db09-0551
By:
- Nicolson, Tamara J.;
- Bellomo, Elisa A.;
- Wijesekara, Nadeeja;
- Loder, Merewyn K.;
- Baldwin, Jocelyn M.;
- Gyulkhandanyan, Armen V.;
- Koshkin, Vasilij;
- Tarasov, Andrei I.;
- Carzaniga, Raffaella;
- Kronenberger, Katrin;
- Taneja, Tarvinder K.;
- da Silva Xavier, Gabriela;
- Libert, Sarah;
- Froguel, Philippe;
- Scharfmann, Raphael;
- Stetsyuk, Volodymir;
- Ravassard, Philippe;
- Parker, Helen;
- Gribble, Fiona M.;
- Reimann, Frank
Publication type:
Article
TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells.
Published in:
2009
By:
- da Silva Xavier G;
- Loder MK;
- McDonald A;
- Tarasov AI;
- Carzaniga R;
- Kronenberger K;
- Barg S;
- Rutter GA;
- da Silva Xavier, Gabriela;
- Loder, Merewyn K;
- McDonald, Angela;
- Tarasov, Andrei I;
- Carzaniga, Raffaella;
- Kronenberger, Katrin;
- Barg, Sebastian;
- Rutter, Guy A
Publication type:
journal article
TCF7L2 Regulates Late Events in Insulin Secretion From Pancreatic Islet β-Cells.
Published in:
Diabetes, 2009, v. 58, n. 4, p. 894, doi. 10.2337/db08-1187
By:
- Xavier, Gabriela da Silva;
- Loder, Merewyn K.;
- McDonald, Angela;
- Tarasov, Andrei I.;
- Carzaniga, Raffaella;
- Kronenberger, Katrin;
- Barg, Sebastian;
- Rutter, Guy A.
Publication type:
Article
A rare mutation in ABCC8/SUR1 leading to altered ATP-sensitive K+ channel activity and beta-cell glucose sensing is associated with type 2 diabetes in adults.
Published in:
2008
By:
- Tarasov AI;
- Nicolson TJ;
- Riveline JP;
- Taneja TK;
- Baldwin SA;
- Baldwin JM;
- Charpentier G;
- Gautier JF;
- Froguel P;
- Vaxillaire M;
- Rutter GA;
- Tarasov, Andrei I;
- Nicolson, Tamara J;
- Riveline, Jean-Pierre;
- Taneja, Tarvinder K;
- Baldwin, Stephen A;
- Baldwin, Jocelyn M;
- Charpentier, Guillaume;
- Gautier, Jean-François;
- Froguel, Philippe
Publication type:
journal article
A Rare Mutation in ABCC8/SUR1 Leading to Altered ATP-Sensitive K+ Channel Activity and β-Cell Glucose Sensing Is Associated With Type 2 Diabetes in Adults.
Published in:
Diabetes, 2008, v. 57, n. 6, p. 1595, doi. 10.2337/db07-1547
By:
- Tarasov, Andrei I.;
- Nicolson, Tamara J.;
- Riveline, Jean-Pierre;
- Taneja, Tarvinder K.;
- Baldwin, Stephen A.;
- Baldwin, Jocelyn M.;
- Charpentier, Guillaume;
- Gautier, Jean-François;
- Froguel, Philippe;
- Vaxillaire, Martine;
- Rutter, Guy A.
Publication type:
Article
A Kir6.2 Mutation Causing Neonatal Diabetes Impairs Electrical Activity and Insulin Secretion From INS-1 β-Cells.
Published in:
Diabetes, 2006, v. 55, n. 11, p. 3075, doi. 10.2337/db06-0637
By:
- Tarasov, Andrei I.;
- Welters, Hannah J.;
- Senkel, Sabine;
- Ryffel, Gerhart U.;
- Hattersley, Andrew T.;
- Morgan, Noel G.;
- Ashcroft, Frances M.
Publication type:
Article
ATP sensitivity of the ATP-sensitive K+ channel in intact and permeabilized pancreatic beta-cells.
Published in:
2006
By:
- Tarasov AI;
- Girard CA;
- Ashcroft FM;
- Tarasov, Andrei I;
- Girard, Christophe A J;
- Ashcroft, Frances M
Publication type:
journal article
ATP Sensitivity of the ATP-Sensitive K+ Channel in Intact and Permeabilized Pancreatic β-Cells.
Published in:
Diabetes, 2006, v. 55, n. 9, p. 2446, doi. 10.2337/db06-0360
By:
- Tarasov, Andrei I.;
- Girard, Christophe A. J.;
- Ashcroft, Frances M.
Publication type:
Article
Dopamine signalling in pancreatic islet cells and role in adaptations to metabolic stress.
Published in:
Journal of Pharmacy & Pharmacology, 2024, v. 76, n. 7, p. 861, doi. 10.1093/jpp/rgae049
By:
- Sridhar, Ananyaa;
- Flatt, Peter R;
- Draper, Matthew;
- Tarasov, Andrei I;
- Moffett, R Charlotte;
- Irwin, Nigel;
- Khan, Dawood
Publication type:
Article
Effects of artemether on pancreatic islet morphology, islet cell turnover and α-cell transdifferentiation in insulin-deficient GluCreERT2;ROSA26-eYFP diabetic mice.
Published in:
Journal of Pharmacy & Pharmacology, 2022, v. 74, n. 12, p. 1758, doi. 10.1093/jpp/rgac075
By:
- Sarnobat, Dipak;
- Lafferty, Ryan A;
- Charlotte Moffett, R;
- Tarasov, Andrei I;
- Flatt, Peter R;
- Irwin, Nigel
Publication type:
Article
Editorial: Proglucagon-Derived Peptides.
Published in:
Frontiers in Endocrinology, 2021, v. 12, p. 1, doi. 10.3389/fendo.2021.776871
By:
- Flatt, Peter R.;
- Knop, Filip K.;
- Tarasov, Andrei I.
Publication type:
Article
Taurine rescues pancreatic β‐cell stress by stimulating α‐cell transdifferentiation.
Published in:
Biofactors, 2023, v. 49, n. 3, p. 646, doi. 10.1002/biof.1938
By:
- Sarnobat, Dipak;
- Moffett, R. Charlotte;
- Ma, Jinfang;
- Flatt, Peter R.;
- McClenaghan, Neville H.;
- Tarasov, Andrei I.
Publication type:
Article
Imaging Meets Cytometry: Analyzing Heterogeneous Functional Microscopic Data from Living Cell Populations.
Published in:
Journal of Imaging, 2021, v. 7, n. 1, p. 1, doi. 10.3390/jimaging7010009
By:
- Draper, Matthew;
- Willems, Mara;
- Malahe, Reshwan K.;
- Hamilton, Alexander;
- Tarasov, Andrei I.
Publication type:
Article
Electrophysiological properties of human beta-cell lines EndoC-βH1 and -βH2 conform with human beta-cells.
Published in:
Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-34743-7
By:
- Hastoy, Benoît;
- Godazgar, Mahdieh;
- Clark, Anne;
- Nylander, Vibe;
- Spiliotis, Ioannis;
- van de Bunt, Martijn;
- Chibalina, Margarita V.;
- Barrett, Amy;
- Burrows, Carla;
- Tarasov, Andrei I.;
- Scharfmann, Raphael;
- Gloyn, Anna L.;
- Rorsman, Patrik
Publication type:
Article
Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10189-x
By:
- Haythorne, Elizabeth;
- Rohm, Maria;
- van de Bunt, Martijn;
- Brereton, Melissa F.;
- Tarasov, Andrei I.;
- Blacker, Thomas S.;
- Sachse, Gregor;
- Silva dos Santos, Mariana;
- Terron Exposito, Raul;
- Davis, Simon;
- Baba, Otto;
- Fischer, Roman;
- Duchen, Michael R.;
- Rorsman, Patrik;
- MacRae, James I.;
- Ashcroft, Frances M.
Publication type:
Article
GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation.
Published in:
2015
By:
- Shigeto, Makoto;
- Ramracheya, Reshma;
- Tarasov, Andrei I;
- Cha, Chae Young;
- Chibalina, Margarita V;
- Hastoy, Benoit;
- Philippaert, Koenraad;
- Reinbothe, Thomas;
- Rorsman, Nils;
- Salehi, Albert;
- Sones, William R;
- Vergari, Elisa;
- Weston, Cathryn;
- Gorelik, Julia;
- Katsura, Masashi;
- Nikolaev, Viacheslav O;
- Vennekens, Rudi;
- Zaccolo, Manuela;
- Galione, Antony;
- Johnson, Paul R V
Publication type:
journal article
GLP-1 metabolite GLP-1(9–36) is a systemic inhibitor of mouse and human pancreatic islet glucagon secretion.
Published in:
Diabetologia, 2024, v. 67, n. 3, p. 528, doi. 10.1007/s00125-023-06060-w
By:
- Gandasi, Nikhil R.;
- Gao, Rui;
- Kothegala, Lakshmi;
- Pearce, Abigail;
- Santos, Cristiano;
- Acreman, Samuel;
- Basco, Davide;
- Benrick, Anna;
- Chibalina, Margarita V.;
- Clark, Anne;
- Guida, Claudia;
- Harris, Matthew;
- Johnson, Paul R. V.;
- Knudsen, Jakob G.;
- Ma, Jinfang;
- Miranda, Caroline;
- Shigeto, Makoto;
- Tarasov, Andrei I.;
- Yeung, Ho Yan;
- Thorens, Bernard
Publication type:
Article
The Mitochondrial Ca2+ Uniporter MCU Is Essential for Glucose-Induced ATP Increases in Pancreatic β-Cells.
Published in:
PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0039722
By:
- Tarasov, Andrei I.;
- Semplici, Francesca;
- Ravier, Magalie A.;
- Bellomo, Elisa A.;
- Pullen, Timothy J.;
- Gilon, Patrick;
- Sekler, Israel;
- Rizzuto, Rosario;
- Rutter, Guy A.
Publication type:
Article
Molecular determinants and intracellular targets of taurine signalling in pancreatic islet β‐cells.
Published in:
Acta Physiologica, 2024, v. 240, n. 3, p. 1, doi. 10.1111/apha.14101
By:
- Turbitt, Julie;
- Moffett, R. Charlotte;
- Brennan, Lorraine;
- Johnson, Paul R. V.;
- Flatt, Peter R.;
- McClenaghan, Neville H.;
- Tarasov, Andrei I.
Publication type:
Article
Nicotinic Signaling Stimulates Glucagon Secretion in Mouse and Human Pancreatic α-Cells.
Published in:
Diabetes, 2025, v. 74, n. 1, p. 53, doi. 10.2337/db23-0809
By:
- Hamilton, Alexander;
- Zhang, Quan;
- Gao, Rui;
- Hill, Thomas G.;
- Salehi, Albert;
- Knudsen, Jakob G.;
- Draper, Matthew B.;
- Johnson, Paul R.V.;
- Rorsman, Patrik;
- Tarasov, Andrei I.
Publication type:
Article
340-LB: Optogenetic Control of a-Cell Electrical Activity and Glucagon Secretion in Intact Islets.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-340-LB
By:
- MIRANDA, CAROLINE A.;
- DOU, HAIQIANG;
- TOLö, JOHAN;
- TARASOV, ANDREI I.;
- RORSMAN, PATRIK
Publication type:
Article
Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca2+ Mobilization From Acidic Stores in Pancreatic α-Cells.
Published in:
2018
By:
- Hamilton, Alexander;
- Quan Zhang;
- Salehi, Albert;
- Willems, Mara;
- Knudsen, Jakob G.;
- Ringgaard, Anna K.;
- Chapman, Caroline E.;
- Gonzalez-Alvarez, Alejandro;
- Surdo, Nicoletta C.;
- Zaccolo, Manuela;
- Basco, Davide;
- Johnson, Paul R. V.;
- Ramracheya, Reshma;
- Rutter, Guy A.;
- Galione, Antony;
- Rorsman, Patrik;
- Tarasov, Andrei I.;
- Zhang, Quan
Publication type:
journal article
Increased Expression of the Diabetes Gene SOX4 Reduces Insulin Secretion by Impaired Fusion Pore Expansion.
Published in:
2016
By:
- Collins, Stephan C.;
- Hyun Woong Do;
- Hastoy, Benoit;
- Hugill, Alison;
- Adam, Julie;
- Chibalina, Margarita V.;
- Galvanovskis, Juris;
- Godazgar, Mahdieh;
- Sheena Lee;
- Goldsworthy, Michelle;
- Salehi, Albert;
- Tarasov, Andrei I.;
- Rosengren, Anders H.;
- Cox, Roger;
- Rorsman, Patrik;
- Do, Hyun Woong;
- Lee, Sheena
Publication type:
journal article

Works by Tarasov, Andrei I.

Comparative Effects of GLP-1 and GLP-2 on Beta-Cell Function, Glucose Homeostasis and Appetite Regulation.

Cafeteria diet compromises natural adaptations of islet cell transdifferentiation and turnover in pregnancy.

Liver glycogen phosphorylase is upregulated in glioblastoma and provides a metabolic vulnerability to high dose radiation.

[P<sup>3</sup>]PP, a stable, long‐acting pancreatic polypeptide analogue, evokes weight lowering and pancreatic beta‐cell‐protective effects in obesity‐associated diabetes.

Pancreatic islet cell plasticity: Pathogenic or therapeutically exploitable?

Identification of the PIP<sub>2</sub>-binding site on Kir6.2 by molecular modelling and functional analysis.

Insulin Gene Mutations Resulting in Early-Onset Diabetes: Marked Differences in Clinical Presentation, Metabolic Status, and Pathogenic Effect Through Endoplasmic Reticulum Retention.

Insulin Storage and Glucose Homeostasis in Mice Null for the Granule Zinc Transporter ZnT8 and Studies of the Type 2 Diabetes-Associated Variants.

TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells.

TCF7L2 Regulates Late Events in Insulin Secretion From Pancreatic Islet β-Cells.

A rare mutation in ABCC8/SUR1 leading to altered ATP-sensitive K+ channel activity and beta-cell glucose sensing is associated with type 2 diabetes in adults.

A Rare Mutation in ABCC8/SUR1 Leading to Altered ATP-Sensitive K<sup>+</sup> Channel Activity and β-Cell Glucose Sensing Is Associated With Type 2 Diabetes in Adults.

A Kir6.2 Mutation Causing Neonatal Diabetes Impairs Electrical Activity and Insulin Secretion From INS-1 β-Cells.

ATP sensitivity of the ATP-sensitive K+ channel in intact and permeabilized pancreatic beta-cells.

ATP Sensitivity of the ATP-Sensitive K<sup>+</sup> Channel in Intact and Permeabilized Pancreatic β-Cells.

Dopamine signalling in pancreatic islet cells and role in adaptations to metabolic stress.

Effects of artemether on pancreatic islet morphology, islet cell turnover and α-cell transdifferentiation in insulin-deficient Glu<sup>CreERT2</sup>;ROSA26-eYFP diabetic mice.

Editorial: Proglucagon-Derived Peptides.

Taurine rescues pancreatic β‐cell stress by stimulating α‐cell transdifferentiation.

Imaging Meets Cytometry: Analyzing Heterogeneous Functional Microscopic Data from Living Cell Populations.

Electrophysiological properties of human beta-cell lines EndoC-βH1 and -βH2 conform with human beta-cells.

Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells.

GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation.

GLP-1 metabolite GLP-1(9–36) is a systemic inhibitor of mouse and human pancreatic islet glucagon secretion.

The Mitochondrial Ca<sup>2+</sup> Uniporter MCU Is Essential for Glucose-Induced ATP Increases in Pancreatic <sup>β</sup>-Cells.

Molecular determinants and intracellular targets of taurine signalling in pancreatic islet β‐cells.

Nicotinic Signaling Stimulates Glucagon Secretion in Mouse and Human Pancreatic α-Cells.

340-LB: Optogenetic Control of a-Cell Electrical Activity and Glucagon Secretion in Intact Islets.

Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca<sup>2+</sup> Mobilization From Acidic Stores in Pancreatic α-Cells.

Increased Expression of the Diabetes Gene SOX4 Reduces Insulin Secretion by Impaired Fusion Pore Expansion.