Works by Tapscott, Stephen J.

Results: 85

Suspended Tissue Open Microfluidic Patterning (STOMP).

Published in:

Advanced Science, 2025, v. 12, n. 25, p. 1, doi. 10.1002/advs.202501148

By:

Haack, Amanda J.;
Brown, Lauren G.;
Goldstein, Alex J.;
Mulimani, Priti;
Berthier, Jean;
Viswanathan, Asha R.;
Kopyeva, Irina;
Whitten, Jamison M.;
Lin, Ariel;
Nguyen, Serena H.;
Leahy, Thomas P.;
Bouker, Ella E.;
Padgett, Ruby M.;
Mazzawi, Natalie A.;
Tokihiro, Jodie C.;
Bretherton, Ross C.;
Wu, Aaliyah;
Tapscott, Stephen J.;
DeForest, Cole A.;
Popowics, Tracy E.

Publication type:

Article

Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.82057

By:

Spens, Amy E.;
Sutliff, Nicholas A.;
Bennett, Sean R.;
Campbell, Amy E.;
Tapscott, Stephen J.

Publication type:

Article

Requirement of the mouse I-mfa gene for placental development and skeletal patterning.

Published in:

EMBO Journal, 1998, v. 17, n. 21, p. 6276, doi. 10.1093/emboj/17.21.6276

By:

Kraut, Norbert;
Snider, Lauren;
Chen, C.-M. Amy;
Tapscott, Stephen J.;
Groudine, Mark

Publication type:

Article

AI driven analysis of MRI to measure health and disease progression in FSHD.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-65802-x

By:

Riem, Lara;
DuCharme, Olivia;
Cousins, Matthew;
Feng, Xue;
Kenney, Allison;
Morris, Jacob;
Tapscott, Stephen J.;
Tawil, Rabi;
Statland, Jeff;
Shaw, Dennis;
Wang, Leo;
Walker, Michaela;
Lewis, Leann;
Jacobs, Michael A.;
Leung, Doris G.;
Friedman, Seth D.;
Blemker, Silvia S.

Publication type:

Article

Identification of SMCHD1 domains for nuclear localization, homo-dimerization, and protein cleavage.

Published in:

Skeletal Muscle, 2018, v. 8, n. 1, p. N.PAG, doi. 10.1186/s13395-018-0172-z

By:

Hiramuki, Yosuke;
Tapscott, Stephen J.

Publication type:

Article

Epigenetic regulation of the X-chromosomal macrosatellite repeat encoding for the cancer/testis gene CT47.

Published in:

European Journal of Human Genetics, 2012, v. 20, n. 2, p. 185, doi. 10.1038/ejhg.2011.150

By:

Balog, Judit;
Miller, Dan;
Sanchez-Curtailles, Elena;
Carbo-Marques, Jose;
Block, Gregory;
Potman, Marco;
de Knijff, Peter;
Lemmers, Richard JLF;
Tapscott, Stephen J;
van der Maarel, Silvère M

Publication type:

Article

Large DNA palindromes as a common form of structural chromosome aberrations in human cancers.

Published in:

Human Cell, 2006, v. 19, n. 1, p. 17, doi. 10.1111/j.1749-0774.2005.00003.x

By:

Tanaka, Hisashi;
Bergstrom, Donald A.;
Yao, Meng-Chao;
Tapscott, Stephen J.

Publication type:

Article

Genome-wide analysis of palindrome formation.

Published in:

2010

By:

Diede, Scott J.;
Tanaka, Hisashi;
Bergstrom, Donald A.;
Meng-Chao Yao;
Tapscott, Stephen J.

Publication type:

Letter

Corrigendum: Widespread and nonrandom distribution of DNA palindromes in cancer cells provides a structural platform for subsequent gene amplification.

Published in:

2010

By:

Tanaka, Hisashi;
Bergstrom, Donald A;
Yao, Meng-Chao;
Tapscott, Stephen J

Publication type:

Correction Notice

Widespread and nonrandom distribution of DNA palindromes in cancer cells provides a structural platform for subsequent gene amplification.

Published in:

Nature Genetics, 2005, v. 37, n. 3, p. 320, doi. 10.1038/ng1515

By:

Tanaka, Hisashi;
Bergstrom, Donald A.;
Meng-Chao Yao;
Tapscott, Stephen J.

Publication type:

Article

CTCF-binding sites flank CTG/CAG repeats and form a methylation-sensitive insulator at the DM1 locus.

Published in:

Nature Genetics, 2001, v. 28, n. 4, p. 335, doi. 10.1038/ng570

By:

Filippova, Galina N.;
Thienes, Cortlandt P.;
Penn, Bennett H.;
Cho, Diane H.;
Hu, Ying Jia;
Moore, James M.;
Klesert, Todd R.;
Lobanenkov, Victor V.;
Tapscott, Stephen J.

Publication type:

Article

Mice deficient in Six5 develop cataracts: implications for myotonic dystrophy.

Published in:

Nature Genetics, 2000, v. 25, n. 1, p. 105, doi. 10.1038/75490

By:

Klesert, Todd R.;
Cho, Diane H.;
Clark, John I.;
Maylie, James;
Adelman, John;
Snider, Lauren;
Yuen, Eric C.;
Soriano, Philippe;
Tapscott, Stephen J.

Publication type:

Article

DUX4 Binding to Retroelements Creates Promoters That Are Active in FSHD Muscle and Testis.

Published in:

PLoS Genetics, 2013, v. 9, n. 11, p. 1, doi. 10.1371/journal.pgen.1003947

By:

Young, Janet M.;
Whiddon, Jennifer L.;
Yao, Zizhen;
Kasinathan, Bhavatharini;
Snider, Lauren;
Geng, Linda N.;
Balog, Judit;
Tawil, Rabi;
van der Maarel, Silvère M.;
Tapscott, Stephen J.

Publication type:

Article

Intrinsic Epigenetic Regulation of the D4Z4 Macrosatellite Repeat in a Transgenic Mouse Model for FSHD.

Published in:

PLoS Genetics, 2013, v. 9, n. 4, p. 1, doi. 10.1371/journal.pgen.1003415

By:

Krom., Yvonne D.;
Thijssen., Peter E.;
Young, Janet M.;
den Hamer, Bianca;
Balog, Judit;
Yao, Zizhen;
Maves, Lisa;
Snider, Lauren;
Knopp, Paul;
Zammit, Peter S.;
Rijkers, Tonnie;
van Engelen, Baziel G. M.;
Padberg, George W.;
Frants, Rune R.;
Tawil, Rabi;
Tapscott, Stephen J.;
van der Maarel, Silvère M.

Publication type:

Article

CTCF cis-Regulates Trinucleotide Repeat Instability in an Epigenetic Manner: A Novel Basis for Mutational Hot Spot Determination.

Published in:

PLoS Genetics, 2008, v. 4, n. 11, p. 1, doi. 10.1371/journal.pgen.1000257

By:

Libby, Randell T.;
Hagerman, Katharine A.;
Pineda, Victor V.;
Lau, Rachel;
Cho, Diane H.;
Baccam, Sandy L.;
Axford, Michelle M.;
Cleary, John D.;
Moore, James M.;
Sopher, Bryce L.;
Tapscott, Stephen J.;
Filippova, Galina N.;
Pearson, Christopher E.;
La Spada, Albert R.

Publication type:

Article

Inhibition of mammalian muscle differentiation by regeneration blastema extract of Sternopygus macrurus.

Published in:

Developmental Dynamics, 2008, v. 237, n. 10, p. 2830, doi. 10.1002/dvdy.21702

By:

Kim, Hyun-Jung;
Archer, Eric;
Escobedo, Norma;
Tapscott, Stephen J.;
Unguez, Graciela A.

Publication type:

Article

Regional and bilateral MRI and gene signatures in facioscapulohumeral dystrophy: implications for clinical trial design and mechanisms of disease progression.

Published in:

Human Molecular Genetics, 2024, v. 33, n. 8, p. 698, doi. 10.1093/hmg/ddae007

By:

Wong, Chao-Jen;
Friedman, Seth D;
Snider, Lauren;
Bennett, Sean R;
Jones, Takako I;
Jones, Peter L;
Shaw, Dennis W W;
Blemker, Silvia S;
Riem, Lara;
DuCharme, Olivia;
Lemmers, Richard J F L;
Maarel, Silvère M van der;
Wang, Leo H;
Tawil, Rabi;
Statland, Jeffrey M;
Tapscott, Stephen J

Publication type:

Article

snRNA-seq analysis in multinucleated myogenic FSHD cells identifies heterogeneous FSHD transcriptome signatures associated with embryonic-like program activation and oxidative stress-induced apoptosis.

Published in:

Human Molecular Genetics, 2024, v. 33, n. 3, p. 284, doi. 10.1093/hmg/ddad186

By:

Zheng, Dongxu;
Wondergem, Annelot;
Kloet, Susan;
Willemsen, Iris;
Balog, Judit;
Tapscott, Stephen J;
Mahfouz, Ahmed;
van den Heuvel, Anita;
Maarel, Silvère M van der

Publication type:

Article

Human DUX4 and porcine DUXC activate similar early embryonic programs in pig muscle cells: implications for preclinical models of FSHD.

Published in:

Human Molecular Genetics, 2023, v. 32, n. 11, p. 1864, doi. 10.1093/hmg/ddad021

By:

Nip, Yee;
Bennett, Sean R;
Smith, Andrew A;
Jones, Takako I;
Jones, Peter L;
Tapscott, Stephen J

Publication type:

Article

Elevated plasma complement components in facioscapulohumeral dystrophy.

Published in:

Human Molecular Genetics, 2022, v. 31, n. 11, p. 1821, doi. 10.1093/hmg/ddab364

By:

Wong, Chao-Jen;
Wang, Leo;
Holers, V Michael;
Frazer-Abel, Ashley;
Maarel, Silvère M van der;
Tawil, Rabi;
Statland, Jeffrey M;
Tapscott, Stephen J;
Network, ReSolve

Publication type:

Article

Canine DUXC: implications for DUX4 retrotransposition and preclinical models of FSHD.

Published in:

Human Molecular Genetics, 2022, v. 31, n. 10, p. 1694, doi. 10.1093/hmg/ddab352

By:

Wong, Chao-Jen;
Whiddon, Jennifer L;
Langford, Ashlee T;
Belleville, Andrea E;
Tapscott, Stephen J

Publication type:

Article

Muscle pathology grade for facioscapulohumeral muscular dystrophy biopsies.

Published in:

2015

By:

Statland, Jeffrey M.;
Shah, Bharati;
Henderson, Don;
Van Der Maarel, Silvere;
Tapscott, Stephen J.;
Tawil, Rabi

Publication type:

journal article

Reciprocal inhibition between Pax7 and muscle regulatory factors modulates myogenic cell fate determination.

Published in:

Journal of Cell Biology, 2007, v. 177, n. 5, p. 769, doi. 10.1083/jcb.200608122

By:

Olguin, Hugo C.;
Yang, Zhihong;
Tapscott, Stephen J.;
Olwin, Bradley B.

Publication type:

Article

MyoD inhibits Fstl 1 and Utrn expression by inducing transcription of miR-206.

Published in:

Journal of Cell Biology, 2006, v. 175, n. 1, p. 77, doi. 10.1083/jcb.200603039

By:

Rosenberg, Miriam I.;
Georges, Sara A.;
Asawachaicharn, Amy;
Analau, Erwin;
Tapscott, Stephen J.

Publication type:

Article

Cell-lineage regulated myogenesis for dystrophin replacement: a novel therapeutic approach for treatment of muscular dystrophy.

Published in:

Human Molecular Genetics, 2008, v. 17, n. 16, p. 2507, doi. 10.1093/hmg/ddn151

By:

Kimura, En;
Han, Jay J.;
Li, Sheng;
Fall, Brent;
Ra, Jennifer;
Haraguchi, Miki;
Tapscott, Stephen J.;
Chamberlain, Jeffrey S.

Publication type:

Article

An antisense transcript spanning the CGG repeat region of FMR1 is upregulated in premutation carriers but silenced in full mutation individuals.

Published in:

Human Molecular Genetics, 2007, v. 16, n. 24, p. 3174, doi. 10.1093/hmg/ddm293

By:

Ladd, Paula D.;
Smith, Leslie E.;
Rabaia, Natalia A.;
Moore, James M.;
Georges, Sara A.;
Hansen, R. Scott;
Hagerman, Randi J.;
Tassone, Flora;
Tapscott, Stephen J.;
Filippova, Galina N.

Publication type:

Article

Gene expression in Huntington's disease skeletal muscle: a potential biomarker.

Published in:

Human Molecular Genetics, 2005, v. 14, n. 13, p. 1863, doi. 10.1093/hmg/ddi192

By:

Strand, Andrew D.;
Aragaki, Aaron K.;
Shaw, Dennis;
Bird, Thomas;
Holton, Janice;
Turner, Christopher;
Tapscott, Stephen J.;
Tabrizi, Sarah J.;
Schapira, Anthony H.;
Kooperberg, Charles;
Olson, James M.

Publication type:

Article

Expression profiling of FSHD muscle supports a defect in specific stages of myogenic differentiation.

Published in:

Human Molecular Genetics, 2003, v. 12, n. 22, p. 2895, doi. 10.1093/hmg/ddg327

By:

Winokur, Sara T.;
Chen, Yi-Wen;
Masny, Peter S.;
Martin, Jorge H.;
Ehmsen, Jeffrey T.;
Tapscott, Stephen J.;
van der Maarel, Silvere M.;
Hayashi, Yukiko;
Flanigan, Kevin M.

Publication type:

Article

Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain.

Published in:

Human Molecular Genetics, 2002, v. 11, n. 17, p. 1911, doi. 10.1093/hmg/11.17.1911

By:

Luthi-Carter, Ruth;
Hanson, Sarah A.;
Strand, Andrew D.;
Bergstrom, Donald A.;
Chun, Wanjoo;
Peters, Nikki L.;
Woods, Annette M.;
Chan, Edmond Y.;
Kooperberg, Charles;
Krainc, Dimitri;
Young, Anne B.;
Tapscott, Stephen J.;
Olson, James M.

Publication type:

Article

Identification of transcriptional targets for Six5: implication for the pathogenesis of myotonic dystrophy type 1.

Published in:

Human Molecular Genetics, 2002, v. 11, n. 9, p. 1045, doi. 10.1093/hmg/11.9.1045

By:

Sato, Shigeru;
Nakamura, Miwa;
Cho, Diane H.;
Tapscott, Stephen J.;
Ozaki, Hidenori;
Kawakami, Kiyoshi

Publication type:

Article

Surgical management of superficial siderosis following cervical nerve root avulsion.

Published in:

1996

By:

Tapscott, Stephen J.;
Eskridge, Joseph;
Kliot, Michel;
Tapscott, S J;
Eskridge, J;
Kliot, M

Publication type:

journal article

Longitudinal study of MRI and functional outcome measures in facioscapulohumeral muscular dystrophy.

Published in:

2021

By:

Wang, Leo H.;
Shaw, Dennis W. W.;
Faino, Anna;
Budech, Christopher B.;
Lewis, Leann M.;
Statland, Jeffrey;
Eichinger, Katy;
Tapscott, Stephen J.;
Tawil, Rabi N.;
Friedman, Seth D.

Publication type:

journal article

Adapting MRI as a clinical outcome measure for a facioscapulohumeral muscular dystrophy trial of prednisone and tacrolimus: case report.

Published in:

2021

By:

Wang, Leo H.;
Johnstone, Laura M.;
Bindschadler, Michael;
Tapscott, Stephen J.;
Friedman, Seth D.

Publication type:

journal article

Discriminative motif analysis of high-throughput dataset.

Published in:

Bioinformatics, 2014, v. 30, n. 6, p. 775, doi. 10.1093/bioinformatics/btt615

By:

Yao, Zizhen;
MacQuarrie, Kyle L.;
Fong, Abraham P.;
Tapscott, Stephen J.;
Ruzzo, Walter L.;
Gentleman, Robert C.

Publication type:

Article

A conserved motif N-terminal to the DNA-binding domains of myogenic bHLH transcription factors mediates cooperative DNA binding with Pbx–Meis1/Prep1.

Published in:

Nucleic Acids Research, 1999, v. 27, n. 18, p. 3752, doi. 10.1093/nar/27.18.3752

By:

Knoepfler, Paul S.;
Bergstrom, Don A.;
Uetsuki, Taichi;
Dac-Korytko, Ia;
Sun, Y. Henry;
Wright, Woodring E.;
Tapscott, Stephen J.;
Kamps, Mark P.

Publication type:

Article

TWIST1 Heterodimerization with E12 Requires Coordinated Protein Phosphorylation to Regulate Periostin Expression.

Published in:

Cancers, 2019, v. 11, n. 9, p. 1392, doi. 10.3390/cancers11091392

By:

Mikheeva, Svetlana A.;
Camp, Nathan D.;
Huang, Lei;
Jain, Antrix;
Jung, Sung Yun;
Avci, Naze G.;
Tokita, Mari;
Wolf-Yadlin, Alejandro;
Zhang, Jing;
Tapscott, Stephen J.;
Rostomily, Robert C.;
Mikheev, Andrei M.

Publication type:

Article

Stuck in a balancing act.

Published in:

Cell Cycle, 2011, v. 10, n. 19, p. 1

By:

MacQuarrie, Kyle L.;
Tapscott, Stephen J.

Publication type:

Article

BMP-2 mediates retinoid-induced apoptosis in medulloblastoma cells through a paracrine effect.

Published in:

Nature Medicine, 2003, v. 9, n. 8, p. 1033, doi. 10.1038/nm904

By:

Hallahan, Andrew R.;
Pritchard, Joel I.;
Chandraratna, Roshantha A.S.;
Ellenbogen, Richard G.;
Geyer, J. Russell;
Overland, Ryan P.;
Strand, Andrew D.;
Tapscott, Stephen J.;
Olson, James M.

Publication type:

Article

Comparison of Genome-Wide Binding of MyoD in Normal Human Myogenic Cells and Rhabdomyosarcomas Identifies Regional and Local Suppression of Promyogenic Transcription Factors.

Published in:

Molecular & Cellular Biology, 2013, v. 33, n. 4, p. 773, doi. 10.1128/MCB.00916-12

By:

MacQuarrie, Kyle L.;
Zizhen Yao;
Fong, Abraham P.;
Diede, Scott J.;
Rudzinski, Erin R.;
Hawkins, Douglas S.;
Tapscott, Stephen J.

Publication type:

Article

Intrastrand Annealing Leads to the Formation of a Large DNA Palindrome and Determines the Boundaries of Genomic Amplification in Human Cancer.

Published in:

Molecular & Cellular Biology, 2007, v. 27, n. 6, p. 1, doi. 10.1128/MCB.01313-06

By:

Tanaka, Hisashi;
Yi Cao;
Bergstrom, Donald A.;
Kooperberg, Charles;
Tapscott, Stephen J.;
Meng-Chao Yao

Publication type:

Article

Successful Regional Delivery and Long-term Expression of a Dystrophin Gene in Canine Muscular Dystrophy: A Preclinical Model for Human Therapies.

Published in:

Molecular Therapy, 2012, v. 20, n. 8, p. 1501, doi. 10.1038/mt.2012.111

By:

Wang, Zejing;
Storb, Rainer;
Halbert, Christine L;
Banks, Glen B.;
Butts, Tiffany M.;
Finn, Eric E.;
Allen, James M.;
Miller, A. Dusty;
Chamberlain, Jeffrey S.;
Tapscott, Stephen J.

Publication type:

Article

Expression of Human α1-Antitrypsin in Mice and Dogs Following AAV6 Vector-mediated Gene Transfer to the Lungs.

Published in:

Molecular Therapy, 2010, v. 18, n. 6, p. 1165, doi. 10.1038/mt.2010.51

By:

Halbert, Christine L.;
Madtes, David K.;
Vaughan, Andrew E.;
Zejing Wang;
Storb, Rainer;
Tapscott, Stephen J.;
Miller, A. Dusty

Publication type:

Article

Immune Responses to AAV in Canine Muscle Monitored by Cellular Assays and Noninvasive Imaging.

Published in:

Molecular Therapy, 2010, v. 18, n. 3, p. 617, doi. 10.1038/mt.2009.294

By:

Zejing Wang;
Storb, Rainer;
Donghoon Lee;
Kushmerick, Martin J.;
Baocheng Chu;
Berger, Carolina;
Arnett, Andrea;
Allen, James;
Chamberlain, Jeffrey S.;
Riddell, Stanley R.;
Tapscott, Stephen J.

Publication type:

Article

Hematopoietic Cell Transplantation Provides an Immune-tolerant Platform for Myoblast Transplantation in Dystrophic Dogs.

Published in:

Molecular Therapy, 2008, v. 16, n. 7, p. 1340, doi. 10.1038/mt.2008.102

By:

Parker, Maura H.;
Kuhr, Christian;
Tapscott, Stephen J.;
Storb, Rainer

Publication type:

Article

Sustained AAV-mediated Dystrophin Expression in a Canine Model of Duchenne Muscular Dystrophy with a Brief Course of Immunosuppression.

Published in:

Molecular Therapy, 2007, v. 15, n. 6, p. 1160, doi. 10.1038/sj.mt.6300161

By:

Zejing Wang;
Kuhr, Christian S.;
Allen, James M.;
Blankinship, Michael;
Gregorevic, Paul;
Chamberlain, Jeffrey S.;
Tapscott, Stephen J.;
Storb, Rainer

Publication type:

Article

791. Immunity to AAV-Mediated Gene Therapy in a Random-Bred Canine Model of Duchenne Muscular Dystrophy

Published in:

2005

By:

Wang, Zejing;
Blankinship, Michael J.;
Gregorevic, Paul;
Little, Marie-Terese;
Storb, Rainer J.;
Allen, James M.;
Tapscott, Stephen J.;
Chamberlain, Jeffrey S.;
Kuhr, Christian S.

Publication type:

Abstract

DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response.

Published in:

Journal of Cell Biology, 2024, v. 223, n. 5, p. 1, doi. 10.1083/jcb.202303141

By:

Arends, Tessa;
Hiroshi Tsuchida;
Adeyemi, Richard O.;
Tapscott, Stephen J.

Publication type:

Article

BET bromodomain inhibitors and agonists of the beta-2 adrenergic receptor identified in screens for compounds that inhibit DUX4 expression in FSHD muscle cells.

Published in:

Skeletal Muscle, 2017, v. 7, p. 1, doi. 10.1186/s13395-017-0134-x

By:

Campbell, Amy E.;
Oliva, Jonathan;
Yates, Matthew P.;
Jun Wen Zhong;
Shadle, Sean C.;
Snider, Lauren;
Singh, Nikita;
Shannon Tai;
Yosuke Hiramuki;
Tawil, Rabi;
van der Maarel, Silvère M.;
Tapscott, Stephen J.;
Sverdrup, Francis M.

Publication type:

Article

SMCHD1 regulates a limited set of gene clusters on autosomal chromosomes.

Published in:

Skeletal Muscle, 2017, v. 7, p. 1, doi. 10.1186/s13395-017-0129-7

By:

Mason, Amanda G.;
Slieker, Roderick C.;
Balog, Judit;
Lemmers, Richard J. L. F.;
Chao-Jen Wong;
Zizhen Yao;
Jong-Won Lim;
Filippova, Galina N.;
Ne, Enrico;
Tawil, Rabi;
Heijmans, Bas T.;
Tapscott, Stephen J.;
Van Der Maarel, Silvère M.

Publication type:

Article

Facioscapulohumeral dystrophy: the path to consensus on pathophysiology.

Published in:

Skeletal Muscle, 2014, v. 4, n. 1, p. 1, doi. 10.1186/2044-5040-4-12

By:

Tawil, Rabi;
van der Maarel, Silvère M.;
Tapscott, Stephen J.

Publication type:

Article