Works matching AU Tanzi, Rudolph E.

Results: 215

Development of Carbon‐11 Labeled Pyrimidine Derivatives as Novel Positron Emission Tomography (PET) Agents Enabling Brain Sigma‐1 Receptor Imaging.

Published in:

Advanced Science, 2025, v. 12, n. 21, p. 1, doi. 10.1002/advs.202414827

By:

Bai, Ping;
Gomm, Ashley;
Yoo, Chi‐Hyeon;
Mondal, Prasenjit;
Lobo, Fleur Marie;
Meng, Hui;
Zhou, Yanting;
Xie, Weiyao;
Wey, Hsiao‐Ying;
Tanzi, Rudolph E.;
Zhang, Can;
Wang, Changning;
Lan, Yu

Publication type:

Article

Polygenic hazard score models for the prediction of Alzheimer's free survival using the lasso for Cox's proportional hazards model.

Published in:

Genetic Epidemiology, 2025, v. 49, n. 1, p. 1, doi. 10.1002/gepi.22581

By:

Hahn, Georg;
Prokopenko, Dmitry;
Hecker, Julian;
Lutz, Sharon M.;
Mullin, Kristina;
Tanzi, Rudolph E.;
DeSantis, Stacia;
Lange, Christoph

Publication type:

Article

Genome‐wide association analysis of COVID‐19 mortality risk in SARS‐CoV‐2 genomes identifies mutation in the SARS‐CoV‐2 spike protein that colocalizes with P.1 of the Brazilian strain.

Published in:

Genetic Epidemiology, 2021, v. 45, n. 7, p. 685, doi. 10.1002/gepi.22421

By:

Hahn, Georg;
Wu, Chloe M.;
Lee, Sanghun;
Lutz, Sharon M.;
Khurana, Surender;
Baden, Lindsey R.;
Haneuse, Sebastien;
Qiao, Dandi;
Hecker, Julian;
DeMeo, Dawn L.;
Tanzi, Rudolph E.;
Choudhary, Manish C.;
Etemad, Behzad;
Mohammadi, Abbas;
Esmaeilzadeh, Elmira;
Cho, Michael H.;
Li, Jonathan Z.;
Randolph, Adrienne G.;
Laird, Nan M.;
Weiss, Scott T.

Publication type:

Article

On the association analysis of genome-sequencing data: A spatial clustering approach for partitioning the entire genome into nonoverlapping windows.

Published in:

Genetic Epidemiology, 2017, v. 41, n. 4, p. 332, doi. 10.1002/gepi.22040

By:

Loehlein Fier, Heide;
Prokopenko, Dmitry;
Hecker, Julian;
Cho, Michael H.;
Silverman, Edwin K.;
Weiss, Scott T.;
Tanzi, Rudolph E.;
Lange, Christoph

Publication type:

Article

Adult neurogenesis in Alzheimer's disease.

Published in:

Hippocampus, 2023, v. 33, n. 4, p. 307, doi. 10.1002/hipo.23504

By:

Choi, Se Hoon;
Tanzi, Rudolph E.

Publication type:

Article

The genetic defect in familial Alzheimer's disease is not tightly linked to the amyloid β-protein gene.

Published in:

Nature, 1987, v. 329, n. 6135, p. 156, doi. 10.1038/329156a0

By:

Tanzi, Rudolph E.;
George-Hyslop, Peter H. St;
Haines, Jonathan L.;
Polinsky, Ronald J.;
Nee, Linda;
Foncin, Jean-Francois;
Neve, Rachael L.;
McClatchey, Andrea I.;
Conneally, P. Michael;
Gusella, James F.

Publication type:

Article

Homozygotes for Huntington's disease.

Published in:

Nature, 1987, v. 326, n. 6109, p. 194, doi. 10.1038/326194a0

By:

Wexler, Nancy S.;
Young, Anne B.;
Tanzi, Rudolph E.;
Travers, Helen;
Starosta-Rubinstein, Simon;
Penney, John B.;
Snodgrass, S. Robert;
Shoulson, Ira;
Gomez, Fidela;
Arroyo, Maria A. Ramos;
Penchaszadeh, Graciela K.;
Moreno, Humberto;
Gibbons, Kerin;
Faryniarz, Ann;
Hobbs, Wendy;
Anderson, Mary Anne;
Bonilla, Ernesto;
Conneally, P. Michael;
Gusella, James F.

Publication type:

Article

Deletion of Huntington's disease-linked G8 (D4S10) locus in Wolf-Hirschhorn syndrome.

Published in:

Nature, 1985, v. 318, n. 6041, p. 75, doi. 10.1038/318075a0

By:

Gusella, James F.;
Tanzi, Rudolph E.;
Bader, Patricia I.;
Phelan, Mary C.;
Stevenson, Roger;
Hayden, Michael R.;
Hofman, Karen J.;
Faryniarz, Anne G.;
Gibbons, Kerin

Publication type:

Article

The anesthetic sevoflurane induces tau trafficking from neurons to microglia.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02047-8

By:

Dong, Yuanlin;
Liang, Feng;
Huang, Lining;
Fang, Fang;
Yang, Guang;
Tanzi, Rudolph E.;
Zhang, Yiying;
Quan, Qimin;
Xie, Zhongcong

Publication type:

Article

Development of a New Positron Emission Tomography Imaging Radioligand Targeting RIPK1 in the Brain and Characterization in Alzheimer's Disease.

Published in:

Advanced Science, 2024, v. 11, n. 32, p. 1, doi. 10.1002/advs.202309021

By:

Bai, Ping;
Lan, Yu;
Liu, Yan;
Mondal, Prasenjit;
Gomm, Ashley;
Xu, Yulong;
Wang, Yanli;
Wang, Yongle;
Kang, Leyi;
Pan, Lili;
Bagdasarian, Frederick A.;
Hallisey, Madelyn;
Lobo, Fleur;
Varela, Breanna;
Choi, Se Hoon;
Gomperts, Stephen N.;
Wey, Hsiao‐Ying;
Shen, Shiqian;
Tanzi, Rudolph E.;
Wang, Changning

Publication type:

Article

Structure‐Based Discovery of A Small Molecule Inhibitor of Histone Deacetylase 6 (HDAC6) that Significantly Reduces Alzheimer's Disease Neuropathology.

Published in:

Advanced Science, 2024, v. 11, n. 1, p. 1, doi. 10.1002/advs.202304545

By:

Mondal, Prasenjit;
Bai, Ping;
Gomm, Ashley;
Bakiasi, Grisilda;
Lin, Chih‐Chung Jerry;
Wang, Yanli;
Choi, Se Hoon;
Tanzi, Rudolph E.;
Wang, Changning;
Zhang, Can

Publication type:

Article

Effect of Potent γ-Secretase Modulator in Human Neurons Derived From Multiple Presenilin 1-Induced Pluripotent Stem Cell Mutant Carriers.

Published in:

JAMA Neurology, 2014, v. 71, n. 12, p. 1481, doi. 10.1001/jamaneurol.2014.2482

By:

Qing Liu;
Waltz, Shannon;
Woodruff, Grace;
Ouyang, Joe;
Israel, Mason A.;
Herrera, Cheryl;
Sarsoza, Floyd;
Tanzi, Rudolph E.;
Koo, Edward H.;
Ringman, John M.;
Goldstein, Lawrence S. B.;
Wagner, Steven L.;
Yuan, Shauna H.

Publication type:

Article

Abstracts from the 31st International Symposium on ALS/MND.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2020, v. 21, p. 1, doi. 10.1080/21678421.2020.1828775

By:

Tanzi, Rudolph E.;
Aguzzi, Adriano;
Bosco, Daryl A.;
Carra, Serena;
Cudkowicz, Merit;
Genge, Angela;
Maragakis, Nicholas;
Petri, Susanne;
van den Berg, Leonard H.;
Aho, Valtteri;
Garratt, Chris;
Sarapohja, Toni;
Al-Chalabi, Ammar;
Robert, Brown;
Windebank, Anthony;
Goyal, Namita;
Berry, James;
Staff, Nathan;
Miller, Robert;
Katz, Jonathan

Publication type:

Article

Effects of Aerobic Exercise on Brain Age and Health in Middle-Aged and Older Adults: A Single-Arm Pilot Clinical Trial.

Published in:

Life (2075-1729), 2024, v. 14, n. 7, p. 855, doi. 10.3390/life14070855

By:

Ouyang, An;
Zhang, Can;
Adra, Noor;
Tesh, Ryan A.;
Sun, Haoqi;
Lei, Dan;
Jing, Jin;
Fan, Peng;
Paixao, Luis;
Ganglberger, Wolfgang;
Briggs, Logan;
Salinas, Joel;
Bevers, Matthew B.;
Wrann, Christiane Dorothea;
Chemali, Zeina;
Fricchione, Gregory;
Thomas, Robert J.;
Rosand, Jonathan;
Tanzi, Rudolph E.;
Westover, Michael Brandon

Publication type:

Article

Meditation and Yoga Practices as Potential Adjunctive Treatment of SARS-CoV-2 Infection and COVID-19: A Brief Overview of Key Subjects.

Published in:

Journal of Alternative & Complementary Medicine, 2020, v. 36, n. 7, p. 547, doi. 10.1089/acm.2020.0177

By:

Bushell, William;
Castle, Ryan;
Williams, Michelle A.;
Brouwer, Kimberly C.;
Tanzi, Rudolph E.;
Chopra, Deepak;
Mills, Paul J.

Publication type:

Article

Change in Sense of Nondual Awareness and Spiritual Awakening in Response to a Multidimensional Well-Being Program.

Published in:

Journal of Alternative & Complementary Medicine, 2018, v. 24, n. 4, p. 343, doi. 10.1089/acm.2017.0160

By:

Mills, Paul J.;
Peterson, Christine Tara;
Pung, Meredith A.;
Patel, Sheila;
Weiss, Lizabeth;
Wilson, Kathleen L.;
Doraiswamy, P. Murali;
Martin, Jeffery A.;
Tanzi, Rudolph E.;
Chopra, Deepak

Publication type:

Article

The Self-Directed Biological Transformation Initiative and Well-Being.

Published in:

Journal of Alternative & Complementary Medicine, 2016, v. 22, n. 8, p. 627, doi. 10.1089/acm.2016.0002

By:

Mills, Paul J.;
Wilson, Kathleen L.;
Pung, Meredith A.;
Weiss, Lizabeth;
Patel, Sheila;
Doraiswamy, P. Murali;
Peterson, Christine;
Porter, Valencia;
Schadt, Eric;
Chopra, Deepak;
Tanzi, Rudolph E.

Publication type:

Article

A Smoothed Version of the Lassosum Penalty for Fitting Integrated Risk Models Using Summary Statistics or Individual-Level Data.

Published in:

Genes, 2022, v. 13, n. 1, p. 112, doi. 10.3390/genes13010112

By:

Hahn, Georg;
Prokopenko, Dmitry;
Lutz, Sharon M.;
Mullin, Kristina;
Tanzi, Rudolph E.;
Cho, Michael H.;
Silverman, Edwin K.;
Lange, Christoph

Publication type:

Article

Recovering unused information in genome-wide association studies: the benefit of analyzing SNPs out of Hardy–Weinberg equilibrium.

Published in:

European Journal of Human Genetics, 2009, v. 17, n. 12, p. 1676, doi. 10.1038/ejhg.2009.85

By:

Fardo, David W.;
Becker, K. David;
Bertram, Lars;
Tanzi, Rudolph E.;
Lange, Christoph

Publication type:

Article

Cytokine-mediated inflammation mediates painful neuropathy from metabolic syndrome.

Published in:

PLoS ONE, 2018, v. 13, n. 2, p. 1, doi. 10.1371/journal.pone.0192333

By:

Zhang, Can;
Ward, Joseph;
Dauch, Jacqueline R.;
Tanzi, Rudolph E.;
Cheng, Hsinlin T.

Publication type:

Article

Genomic mechanisms in Alzheimer's disease.

Published in:

Brain Pathology, 2020, v. 30, n. 5, p. 966, doi. 10.1111/bpa.12882

By:

Bertram, Lars;
Tanzi, Rudolph E.

Publication type:

Article

Uptake of HIV-1 Tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands.

Published in:

Nature Medicine, 2000, v. 6, n. 12, p. 1380, doi. 10.1038/82199

By:

Liu, Ying;
Jones, Melina;
Hingtgen, Cynthia M.;
Bu, Guojun;
Laribee, Nick;
Tanzi, Rudolph E.;
Moir, Robert D.;
Nath, Avindra;
He, Johnny J.

Publication type:

Article

Of calcium, caspases, and cognitive decline.

Published in:

Nature Medicine, 1998, v. 4, n. 10, p. 1127, doi. 10.1038/2622

By:

Tanzi, Rudolph E.

Publication type:

Article

Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database.

Published in:

Nature Genetics, 2008, v. 40, n. 7, p. 827, doi. 10.1038/ng.171

By:

Allen, Nicole C.;
Bagade, Sachin;
McQueen, Matthew B.;
Ioannidis, John P. A.;
Kavvoura, Fotini K.;
Khoury, Muin J.;
Tanzi, Rudolph E.;
Bertram, Lars

Publication type:

Article

Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database.

Published in:

Nature Genetics, 2007, v. 39, n. 1, p. 17, doi. 10.1038/ng1934

By:

Bertram, Lars;
McQueen, Matthew B.;
Mullin, Kristina;
Blacker, Deborah;
Tanzi, Rudolph E.

Publication type:

Article

In reply.

Published in:

Nature Genetics, 1999, v. 22, n. 1, p. 21, doi. 10.1038/8732

By:

Blacker, Deborah;
Crystal, Adam S.;
Wilcox, Marsha A.;
Laird, Nan M.;
Tanzi, Rudolph E.

Publication type:

Article

Alpha-2 macroglobulin is genetically associated with Alzheimer disease.

Published in:

Nature Genetics, 1998, v. 19, n. 4, p. 357, doi. 10.1038/1243

By:

Blacker, Deborah;
Wilcox, Marsha A.;
Laird, Nan M.;
Rodes, Linda;
Horvath, Steven M.;
Go, Rodney C.P.;
Perry, Rodney;
Watson, Bracie;
Bassett, Susan S.;
McInnis, Melvin G.;
Albert, Marilyn S.;
Hyman, Bradley T.;
Tanzi, Rudolph E.

Publication type:

Article

Author Correction: The neuronal-specific isoform of BIN1 regulates β-secretase cleavage of APP and Aβ generation in a RIN3-dependent manner.

Published in:

2022

By:

Bhattacharyya, Raja;
Teves, Catarina Amelia Fidalgo;
Long, Alexandra;
Hofert, Madison;
Tanzi, Rudolph E.

Publication type:

Correction Notice

The neuronal-specific isoform of BIN1 regulates β-secretase cleavage of APP and Aβ generation in a RIN3-dependent manner.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-07372-4

By:

Bhattacharrya, Raja;
Teves, Catarina Amelia Fidalgo;
Long, Alexandra;
Hofert, Madison;
Tanzi, Rudolph E.

Publication type:

Article

Corrigendum: The predictive validity of a Brain Care Score for late-life depression and a composite outcome of dementia, stroke, and late-life depression: data from the UK Biobank cohort.

Published in:

2024

By:

Singh, Sanjula D.;
Rivier, Cyprien A.;
Papier, Keren;
Chemali, Zeina;
Gutierrez-Martinez, Leidys;
Parodi, Livia;
Mayerhofer, Ernst;
Senff, Jasper;
Clocchiatti-Tuozzo, Santiago;
Nunley, Courtney;
Newhouse, Amy;
Ouyang, An;
Westover, M. Brandon;
Tanzi, Rudolph E.;
Lazar, Ronald M.;
Pikula, Aleksandra;
Ibrahim, Sarah;
Brouwers, H. Bart;
Howard, Virginia J.;
Howard, George

Publication type:

Correction Notice

The predictive validity of a Brain Care Score for late-life depression and a composite outcome of dementia, stroke, and late-life depression: data from the UK Biobank cohort.

Published in:

Frontiers in Psychiatry, 2024, p. 1, doi. 10.3389/fpsyt.2024.1373797

By:

Singh, Sanjula D.;
Rivier, Cyprien A.;
Papier, Keren;
Chemali, Zeina;
Gutierrez-Martinez, Leidys;
Parodi, Livia;
Mayerhofer, Ernst;
Senff, Jasper;
Clocchiatti-Tuozzo, Santiago;
Nunley, Courtney;
Newhouse, Amy;
Ouyang, An;
Westover, M. Brandon;
Tanzi, Rudolph E.;
Lazar, Ronald M.;
Pikula, Aleksandra;
Ibrahim, Sarah;
Brouwers, H. Bart;
Howard, Virginia J.;
Howard, George

Publication type:

Article

The predictive validity of a Brain Care Score for late-life depression and a composite outcome of dementia, stroke, and late-life depression: data from the UK Biobank cohort.

Published in:

Frontiers in Psychiatry, 2024, p. 1, doi. 10.3389/fpsyt.2024.1373797

By:

Singh, Sanjula D.;
Rivier, Cyprien A.;
Papier, Keren;
Chemali, Zeina;
Gutierrez-Martinez, Leidys;
Parodi, Livia;
Mayerhofer, Ernst;
Senff, Jasper;
Clocchiatti-Tuozzo, Santiago;
Nunley, Courtney;
Newhouse, Amy;
An Ouyang;
Westover, M. Brandon;
Tanzi, Rudolph E.;
Lazar, Ronald M.;
Pikula, Aleksandra;
Ibrahim, Sarah;
Brouwers, H. Bart;
Howard, Virginia J.;
Howard, George

Publication type:

Article

Evaluation of bumetanide as a potential therapeutic agent for Alzheimer's disease.

Published in:

Frontiers in Pharmacology, 2023, v. 14, p. 01, doi. 10.3389/fphar.2023.1190402

By:

Boyarko, Ben;
Podvin, Sonia;
Greenberg, Barry;
Momper, Jeremiah D.;
Yadong Huang;
Gerwick, William H.;
Bang, Anne G.;
Quinti, Luisa;
Griciuc, Ana;
Doo Yeon Kim;
Tanzi, Rudolph E.;
Feldman, Howard H.;
Hook, Vivian

Publication type:

Article

Alzheimer's disease: the cholesterol connection.

Published in:

Nature Neuroscience, 2003, v. 6, n. 4, p. 345, doi. 10.1038/nn0403-345

By:

Puglielli, Luigi;
Tanzi, Rudolph E.;
Kovacs, Dora M.

Publication type:

Article

Caspases land on APP: One small step for apoptosis, one giant leap for amyloidosis?

Published in:

Nature Neuroscience, 1999, v. 2, n. 7, p. 585, doi. 10.1038/10133

By:

Tanzi, Rudolph E.

Publication type:

Article

Involvement of ubiquilin-1 transcript variants in protein degradation and accumulation.

Published in:

Communicative & Integrative Biology, 2011, v. 4, n. 4, p. 428, doi. 10.4161/cib.15283

By:

Haapasalo, Annakaisa;
Viswanathan, Jayashree;
Kurkinen, Kaisa M.A.;
Bertram, Lars;
Soininen, Hilkka;
Dantuma, Nico P.;
Tanzi, Rudolph E.;
Hiltunen, Mikko

Publication type:

Article

Gain-of-function mutations in protein kinase Cα (PKCα) may promote synaptic defects in Alzheimer's disease.

Published in:

Science Signaling, 2016, v. 9, n. 427, p. 1, doi. 10.1126/scisignal.aaf6209

By:

Alfonso, Stephanie I.;
Callender, Julia A.;
Hooli, Basavaraj;
Antal, Corina E.;
Mullin, Kristina;
Sherman, Mathew A.;
Lesné, Sylvain E.;
Leitges, Michael;
Newton, Alexandra C.;
Tanzi, Rudolph E.;
Malinow, Roberto

Publication type:

Article

A γ-Secretase Inhibitor, but Not a γ-Secretase Modulator, Induced Defects in BDNF Axonal Trafficking and Signaling: Evidence for a Role for APP.

Published in:

PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0118379

By:

Weissmiller, April M.;
Natera-Naranjo, Orlangie;
Reyna, Sol M.;
Pearn, Matthew L.;
Zhao, Xiaobei;
Nguyen, Phuong;
Cheng, Soan;
Goldstein, Lawrence S. B.;
Tanzi, Rudolph E.;
Wagner, Steven L.;
Mobley, William C.;
Wu, Chengbiao

Publication type:

Article

Peripheral Surgical Wounding and Age-Dependent Neuroinflammation in Mice.

Published in:

PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0096752

By:

Xu, Zhipeng;
Dong, Yuanlin;
Wang, Hui;
Culley, Deborah J.;
Marcantonio, Edward R.;
Crosby, Gregory;
Tanzi, Rudolph E.;
Zhang, Yiying;
Xie, Zhongcong

Publication type:

Article

The Zinc Dyshomeostasis Hypothesis of Alzheimer's Disease.

Published in:

PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0033552

By:

Craddock, Travis J. A.;
Tuszynski, Jack A.;
Chopra, Deepak;
Casey, Noel;
Goldstein, Lee E.;
Hameroff, Stuart R.;
Tanzi, Rudolph E.

Publication type:

Article

Anesthetic Propofol Attenuates the Isoflurane-Induced Caspase-3 Activation and Ab Oligomerization.

Published in:

PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0027019

By:

Zhang, Yiying;
Zhen, Yu;
Dong, Yuanlin;
Xu, Zhipeng;
Yue, Yun;
Golde, Todd E.;
Tanzi, Rudolph E.;
Moir, Robert D.;
Xie, Zhongcong

Publication type:

Article

Alzheimer's Disease Amyloid-β Links Lens and Brain Pathology in Down Syndrome.

Published in:

PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010659

By:

Moncaster, Juliet A.;
Pineda, Roberto;
Moir, Robert D.;
Suqian Lu;
Burton, Mark A.;
Ghosh, Joy G.;
Ericsson, Maria;
Soscia, Stephanie J.;
Mocofanescu, Anca;
Folkerth, Rebecca D.;
Robb, Richard M.;
Kuszak, Jer R.;
Clark, John I.;
Tanzi, Rudolph E.;
Hunter, David G.;
Goldstein, Lee E.

Publication type:

Article

The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide.

Published in:

PLoS ONE, 2010, v. 5, n. 3, p. 1, doi. 10.1371/journal.pone.0009505

By:

Soscia, Stephanie J.;
Kirby, James E.;
Washicosky, Kevin J.;
Tucker, Stephanie M.;
Ingelsson, Martin;
Hyman, Bradley;
Burton, Mark A.;
Goldstein, Lee E.;
Duong, Scott;
Tanzi, Rudolph E.;
Moir, Robert D.

Publication type:

Article

A novel lysosome‐to‐mitochondria signaling pathway disrupted by amyloid‐β oligomers.

Published in:

EMBO Journal, 2018, v. 37, n. 22, p. N.PAG, doi. 10.15252/embj.2018100241

By:

Norambuena, Andrés;
Wallrabe, Horst;
Cao, Rui;
Wang, Dora Bigler;
Silva, Antonia;
Svindrych, Zdenek;
Periasamy, Ammasi;
Hu, Song;
Tanzi, Rudolph E;
Kim, Doo Yeon;
Bloom, George S

Publication type:

Article

γ-Secretase modulators reduce endogenous amyloid β<sub>42</sub> levels in human neural progenitor cells without altering neuronal differentiation.

Published in:

FASEB Journal, 2015, v. 29, n. 8, p. 3335, doi. 10.1096/fj.15-271015

By:

D'Avanzo, Carla;
Sliwinski, Christopher;
Wagner, Steven L.;
Tanzi, Rudolph E.;
Doo Yeon Kim;
Kovacs, Dora M.

Publication type:

Article

FE65 and FE65L1 amyloid precursor protein-binding protein compound null mice display adult-onset cataract and muscle weakness.

Published in:

FASEB Journal, 2015, v. 29, n. 6, p. 2628, doi. 10.1096/fj.14-261453

By:

Jaehong Suh;
Moncaster, Juliet A.;
Lirong Wang;
Hafeez, Imran;
Herz, Joachim;
Tanzi, Rudolph E.;
Goldstein, Lee E.;
Guénette, Suzanne Y.

Publication type:

Article

Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer’s Aβ peptides.

Published in:

Journal of Biological Inorganic Chemistry (JBIC), 2004, v. 9, n. 8, p. 954, doi. 10.1007/s00775-004-0602-8

By:

Xudong Huang;
Atwood, Craig S.;
Moir, Robert D.;
Hartshorn, Mariana A.;
Tanzi, Rudolph E.;
Bush, Ashley I.

Publication type:

Article

Gene therapy for Alzheimer's disease targeting CD33 reduces amyloid beta accumulation and neuroinflammation.

Published in:

Human Molecular Genetics, 2020, v. 29, n. 17, p. 2920, doi. 10.1093/hmg/ddaa179

By:

Griciuc, Ana;
Federico, Anthony N;
Natasan, Jeyashree;
Forte, Angela M;
McGinty, Danielle;
Nguyen, Huong;
Volak, Adrienn;
LeRoy, Stanley;
Gandhi, Sheetal;
Lerner, Eli P;
Hudry, Eloise;
Tanzi, Rudolph E;
Maguire, Casey A

Publication type:

Article

Analysis of hidradenitis suppurativa–linked mutations in four genes and the effects of PSEN1-P242LfsX11 on cytokine and chemokine expression in macrophages.

Published in:

Human Molecular Genetics, 2019, v. 28, n. 7, p. 1173, doi. 10.1093/hmg/ddy414

By:

Li, Airong;
Peng, Yang;
Taiclet, Lauren M;
Tanzi, Rudolph E

Publication type:

Article

Silencing of the Drosophila ortholog of SOX5 leads to abnormal neuronal development and behavioral impairment.

Published in:

Human Molecular Genetics, 2017, v. 26, n. 8, p. 1472, doi. 10.1093/hmg/ddx051

By:

Li, Airong;
Hooli, Basavaraj;
Mullin, Kristina;
Tate, Rebecca E.;
Bubnys, Adele;
Kirchner, Rory;
Chapman, Brad;
Hofmann, Oliver;
Hide, Winston;
Tanzi, Rudolph E.

Publication type:

Article