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High methionine diet induces beta-amyloid–related transcriptional changes in mouse brain
Published in:
2010
By:
- McCampbell, Alexander;
- Wessner, Keith;
- Toolan, Dawn;
- Podtelezhnikov, Alexei;
- Majercak, John;
- Tanis, Keith Q.;
- Ray, William J.;
- Savage, Mary J.
Publication type:
Abstract
The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease.
Published in:
Scientific Reports, 2017, v. 7, n. 1, p. 1, doi. 10.1038/s41598-017-17370-6
By:
- Cazanave, Sophie;
- Podtelezhnikov, Alexei;
- Jensen, Kristian;
- Seneshaw, Mulugeta;
- Kumar, Divya P.;
- Min, Hae-Ki;
- Santhekadur, Prasanna K.;
- Banini, Bubu;
- Mauro, Adolfo Gabriele;
- M. Oseini, Abdul;
- Vincent, Robert;
- Tanis, Keith Q.;
- Webber, Andrea L.;
- Wang, Liangsu;
- Bedossa, Pierre;
- Mirshahi, Faridoddin;
- Sanyal, Arun J.
Publication type:
Article
Molecular Insights into the Pathogenesis of Alzheimer's Disease and Its Relationship to Normal Aging.
Published in:
PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0029610
By:
- Podtelezhnikov, Alexei A.;
- Tanis, Keith Q.;
- Nebozhyn, Michael;
- Ray, William J.;
- Stone, David J.;
- Loboda, Andrey P.
Publication type:
Article
Author Correction: The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease.
Published in:
2020
By:
- Cazanave, Sophie;
- Podtelezhnikov, Alexei;
- Jensen, Kristian;
- Seneshaw, Mulugeta;
- Kumar, Divya P.;
- Min, Hae-Ki;
- Santhekadur, Prasanna K.;
- Banini, Bubu;
- Mauro, Adolfo Gabriele;
- Oseini, Abdul M.;
- Vincent, Robert;
- Tanis, Keith Q.;
- Webber, Andrea L.;
- Wang, Liangsu;
- Bedossa, Pierre;
- Mirshahi, Faridoddin;
- Sanyal, Arun J.
Publication type:
Correction Notice
Induction of Alzheimer's-like changes in brain of mice expressing mutant APP fed excess methionine.
Published in:
Journal of Neurochemistry, 2011, v. 116, n. 1, p. 82, doi. 10.1111/j.1471-4159.2010.07087.x
By:
- McCampbell, Alexander;
- Wessner, Keith;
- Marlatt, Michael W.;
- Wolffe, Carrie;
- Toolan, Dawn;
- Podtelezhnikov, Alexei;
- Yeh, Suzie;
- Zhang, Rena;
- Szczerba, Peter;
- Tanis, Keith Q.;
- Majercak, John;
- Ray, William J.;
- Savage, Mary
Publication type:
Article
Human Alzheimer's disease gene expression signatures and immune profile in APP mouse models: a discrete transcriptomic view of Aβ plaque pathology.
Published in:
2018
By:
- Rothman, Sarah M.;
- Tanis, Keith Q.;
- Gilliland, Jason;
- Gandhi, Pallavi;
- Ware, Christopher;
- Mahadomrongkul, Veeravan;
- O’Loughlin, Elaine;
- Zeballos, Gonzalo;
- Kennedy, Matthew;
- Mirescu, Christian;
- Malkov, Vladislav;
- Stevens, Richard;
- Klappenbach, Joel;
- Marcus, Jacob;
- Pearson, Michelle;
- Smith, Roger;
- Howell, Bonnie J.;
- O'Loughlin, Elaine
Publication type:
journal article
Transcriptional responses to loss or gain of function of the leucine-rich repeat kinase 2 (LRRK2) gene uncover biological processes modulated by LRRK2 activity.
Published in:
Human Molecular Genetics, 2012, v. 21, n. 1, p. 163, doi. 10.1093/hmg/ddr451
By:
- Nikonova, Elena V.;
- Xiong, Yulan;
- Tanis, Keith Q.;
- Dawson, Valina L.;
- Vogel, Robert L.;
- Finney, Eva M.;
- Stone, David J.;
- Reynolds, Ian J.;
- Kern, Jonathan T.;
- Dawson, Ted M.
Publication type:
Article
Alterations in choroid plexus gene expression in Alzheimer's disease provide inferences for CSF composition and dynamics.
Published in:
2010
By:
- Miller, Miles C.;
- Stopa, Edward G.;
- Nikonova, Elena V.;
- Tanis, Keith Q.;
- Podtelezhnikov, Alexei A.;
- Finney, Eva M.;
- Stone, David J.;
- Camargo, Luiz M.;
- Parker, Lisan;
- Verma, Ajay;
- Baird, Andrew;
- Donahue, John E.;
- Gonzalez, Ana Maria;
- Eliceiri, Brian;
- Silverberg, Gerald D.;
- Klinge, Petra M.;
- Johanson, Conrad E.
Publication type:
Abstract
Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies.
Published in:
Toxicological Sciences, 2022, v. 188, n. 1, p. 4, doi. 10.1093/toxsci/kfac041
By:
- Corton, J Christopher;
- Mitchell, Constance A;
- Auerbach, Scott;
- Bushel, Pierre;
- Ellinger-Ziegelbauer, Heidrun;
- Escobar, Patricia A;
- Froetschl, Roland;
- Harrill, Alison H;
- Johnson, Kamin;
- Klaunig, James E;
- Pandiri, Arun R;
- Podtelezhnikov, Alexei A;
- Rager, Julia E;
- Tanis, Keith Q;
- Laan, Jan Willem van der;
- Vespa, Alisa;
- Yauk, Carole L;
- Pettit, Syril D;
- Sistare, Frank D
Publication type:
Article
Universal Toxicity Gene Signatures for Early Identification of Drug-Induced Tissue Injuries in Rats.
Published in:
Toxicological Sciences, 2021, v. 181, n. 2, p. 148, doi. 10.1093/toxsci/kfab038
By:
- Glaab, Warren E;
- Holder, Daniel;
- He, Yudong D;
- Bailey, Wendy J;
- Gerhold, David L;
- Beare, Carolann;
- Erdos, Zoltan;
- Lane, Pamela;
- Michna, Laura;
- Muniappa, Nagaraja;
- Lawrence, Jeffrey W;
- Tanis, Keith Q;
- Sina, Joseph F;
- Skopek, Thomas R;
- Sistare, Frank D
Publication type:
Article
Development and Application of a Transcriptomic Signature of Bioactivation in an Advanced In Vitro Liver Model to Reduce Drug-induced Liver Injury Risk Early in the Pharmaceutical Pipeline.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 121, doi. 10.1093/toxsci/kfaa094
By:
- Kang, Wen;
- Podtelezhnikov, Alexei A;
- Tanis, Keith Q;
- Pacchione, Stephen;
- Su, Ming;
- Bleicher, Kimberly B;
- Wang, Zhibin;
- Laws, George M;
- Griffiths, Thomas G;
- Kuhls, Matthew C;
- Chen, Qing;
- Knemeyer, Ian;
- Marsh, Donald J;
- Mitra, Kaushik;
- Lebron, Jose;
- Sistare, Frank D
Publication type:
Article
Application of a Rat Liver Drug Bioactivation Transcriptional Response Assay Early in Drug Development That Informs Chemically Reactive Metabolite Formation and Potential for Drug-induced Liver Injury.
Published in:
Toxicological Sciences, 2020, v. 177, n. 1, p. 281, doi. 10.1093/toxsci/kfaa088
By:
- Monroe, James J;
- Tanis, Keith Q;
- Podtelezhnikov, Alexei A;
- Nguyen, Truyen;
- Machotka, Sam V;
- Lynch, Donna;
- Evers, Raymond;
- Palamanda, Jairam;
- Miller, Randy R;
- Pippert, Todd;
- Cabalu, Tamara D;
- Johnson, Timothy E;
- Aslamkhan, Amy G;
- Kang, Wen;
- Tamburino, Alex M;
- Mitra, Kaushik;
- Agrawal, Nancy G B;
- Sistare, Frank D
Publication type:
Article
Quantitative Transcriptional Biomarkers of Xenobiotic Receptor Activation in Rat Liver for the Early Assessment of Drug Safety Liabilities.
Published in:
Toxicological Sciences, 2020, v. 175, n. 1, p. 98, doi. 10.1093/toxsci/kfaa026
By:
- Podtelezhnikov, Alexei A;
- Monroe, James J;
- Aslamkhan, Amy G;
- Pearson, Kara;
- Qin, Chunhua;
- Tamburino, Alex M;
- Loboda, Andrey P;
- Glaab, Warren E;
- Sistare, Frank D;
- Tanis, Keith Q
Publication type:
Article
AhR Activation in Pharmaceutical Development: Applying Liver Gene Expression Biomarker Thresholds to Identify Doses Associated With Tumorigenic Risks in Rats.
Published in:
Toxicological Sciences, 2019, v. 171, n. 1, p. 46, doi. 10.1093/toxsci/kfz125
By:
- Qin, Chunhua;
- Aslamkhan, Amy G;
- Pearson, Kara;
- Tanis, Keith Q;
- Podtelezhnikov, Alexei;
- Frank, Erika;
- Pacchione, Stephen;
- Pippert, Todd;
- Glaab, Warren E;
- Sistare, Frank D
Publication type:
Article
Use of a Bile Salt Export Pump Knockdown Rat Susceptibility Model to Interrogate Mechanism of Drug-Induced Liver Toxicity.
Published in:
Toxicological Sciences, 2019, v. 170, n. 1, p. 180, doi. 10.1093/toxsci/kfz079
By:
- Li, Yutai;
- Evers, Raymond;
- Hafey, Michael J;
- Cheon, Kyeongmi;
- Duong, Hong;
- Lynch, Donna;
- LaFranco-Scheuch, Lisa;
- Pacchione, Stephen;
- Tamburino, Alex M;
- Tanis, Keith Q;
- Geddes, Kristin;
- Holder, Daniel;
- Zhang, Nanyan Rena;
- Kang, Wen;
- Gonzalez, Raymond J;
- Galijatovic-Idrizbegovic, Alema;
- Pearson, Kara M;
- Lebron, Jose A;
- Glaab, Warren E;
- Sistare, Frank D
Publication type:
Article
Comparative transcriptomics of choroid plexus in Alzheimer's disease, frontotemporal dementia and Huntington's disease: implications for CSF homeostasis.
Published in:
Fluids & Barriers of the CNS, 2018, v. 15, n. 1, p. N.PAG, doi. 10.1186/s12987-018-0102-9
By:
- Stopa, Edward G.;
- Tanis, Keith Q.;
- Miller, Miles C.;
- Nikonova, Elena V.;
- Podtelezhnikov, Alexei A.;
- Finney, Eva M.;
- Stone, David J.;
- Camargo, Luiz M.;
- Parker, Lisan;
- Verma, Ajay;
- Baird, Andrew;
- Donahue, John E.;
- Torabi, Tara;
- Eliceiri, Brian P.;
- Silverberg, Gerald D.;
- Johanson, Conrad E.
Publication type:
Article

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