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DUSP4 deficiency enhances CD25 expression and CD4<sup>+</sup> T-cell proliferation without impeding T-cell development.
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- European Journal of Immunology, 2012, v. 42, n. 2, p. 476, doi. 10.1002/eji.201041295
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- Article
SARS‐CoV‐2 spike protein enhances MAP4K3/GLK‐induced ACE2 stability in COVID‐19.
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- EMBO Molecular Medicine, 2022, v. 14, n. 9, p. 1, doi. 10.15252/emmm.202215904
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- Article
MAP4K3/GLK in autoimmune disease, cancer and aging.
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- Journal of Biomedical Science, 2019, v. 26, n. 1, p. N.PAG, doi. 10.1186/s12929-019-0570-5
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- Article
DUSP6 Deficiency Attenuates Neurodegeneration after Global Cerebral Ischemia.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 9, p. 7690, doi. 10.3390/ijms24097690
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- Article
Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 20, p. 7515, doi. 10.3390/ijms21207515
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- Article
Regulation of Dual-Specificity Phosphatase (DUSP) Ubiquitination and Protein Stability.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 11, p. 2668, doi. 10.3390/ijms20112668
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- Article
RBM4a-SRSF3-MAP4K4 Splicing Cascade Constitutes a Molecular Mechanism for Regulating Brown Adipogenesis.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 9, p. 2646, doi. 10.3390/ijms19092646
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- Article
Mechanisms of Enhanced Nuclear Translocation of the Transcription Factors c-Rel and NF-kB by CD28 Costimulation in Human T Lymphocytes<sup>a</sup>.
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- Annals of the New York Academy of Sciences, 1995, v. 766, n. 1, p. 220, doi. 10.1111/j.1749-6632.1995.tb26669.x
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- Article
DUSP22 inhibits lung tumorigenesis by suppression of EGFR/c-Met signaling.
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- Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02038-8
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- Article
The phosphatase DUSP22 inhibits UBR2-mediated K63-ubiquitination and activation of Lck downstream of TCR signalling.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-44843-w
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- Article
PP4 Is Essential for Germinal Center Formation and Class Switch Recombination in Mice.
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- PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0107505
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- Article
The Serine/Threonine Phosphatase PP4 Is Required for Pro-B Cell Development through Its Promotion of Immunoglobulin VDJ Recombination.
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- PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0068804
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- Article
Proteomic analysis of resting and thrombin-stimulated platelets reveals the translocation and functional relevance of HIP-55 in platelets.
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- Proteomics, 2009, v. 9, n. 18, p. 4340, doi. 10.1002/pmic.200900024
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- Article
Association of TRAIL receptor with phosphatase SHP-1 enables repressing T cell receptor signaling and T cell activation through inactivating Lck.
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- Journal of Biomedical Science, 2024, v. 31, n. 1, p. 1, doi. 10.1186/s12929-024-01023-8
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- Article
ACE2 in chronic disease and COVID-19: gene regulation and post-translational modification.
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- Journal of Biomedical Science, 2023, v. 30, n. 1, p. 1, doi. 10.1186/s12929-023-00965-9
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- Article
DUSP3 regulates phosphorylation-mediated degradation of occludin and is required for maintaining epithelial tight junction.
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- Journal of Biomedical Science, 2022, v. 29, n. 1, p. 1, doi. 10.1186/s12929-022-00826-x
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- Article
Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis.
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- BMC Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12916-023-02745-6
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- Article
Leukocyte-specific adaptor protein Grap2 interacts with hematopoietic progenitor kinase 1 (HPK1) to activate JNK signaling pathway in T lymphocytes.
- Published in:
- Oncogene, 2001, v. 20, n. 14, p. 1703, doi. 10.1038/sj.onc.1204224
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- Article
Down-regulation of the c-Jun N-terminal kinase (JNK) phosphatase M3/6 and activation of JNK by hydrogen peroxide and pyrrolidine dithiocarbamate.
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- Oncogene, 2001, v. 20, n. 3, p. 367, doi. 10.1038/sj.onc.1204105
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- Article
Caspase-mediated cleavage and functional changes of hematopoietic progenitor kinase 1 (HPK1).
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- Oncogene, 1999, v. 18, n. 51, p. 7370, doi. 10.1038/sj.onc.1203116
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- Article
Role of c-Jun N-terminal kinase 1 (JNK1) in cell cycle checkpoint activated by the protease inhibitor N-acetyl-leucinyl-leucinyl-norleucinal.
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- Oncogene, 1999, v. 18, n. 50, p. 6974, doi. 10.1038/sj.onc.1203195
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- Article
Hematopoietic progenitor kinase-1 (HPK1) stress response signaling pathway activates IκB kinases (IKK-α/β) and IKK-β is a developmentally regulated protein kinase.
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- Oncogene, 1999, v. 18, n. 40, p. 5514, doi. 10.1038/sj.onc.1202740
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- Article
Differential regulation of mitogen-activated protein kinases by microtubule-binding agents in human breast cancer cells.
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- Oncogene, 1999, v. 18, n. 2, p. 377, doi. 10.1038/sj.onc.1202305
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- Article
The germinal center kinase (GCK)-related protein kinases HPK1 and KHS are candidates for highly selective signal transducers of Crk family adapter proteins.
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- Oncogene, 1998, v. 17, n. 15, p. 1893, doi. 10.1038/sj.onc.1202108
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- Article
Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin.
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- Oncogene, 1998, v. 17, n. 2, p. 173, doi. 10.1038/sj.onc.1201941
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- Article
The kinase GLK controls autoimmunity and NF-?B signaling by activating the kinase PKC-? in T cells.
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- Nature Immunology, 2011, v. 12, n. 11, p. 1113, doi. 10.1038/ni.2121
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- Article
Hematopoietic progenitor kinase 1 negatively regulates T cell receptor signaling and T cell–mediated immune responses.
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- Nature Immunology, 2007, v. 8, n. 1, p. 84, doi. 10.1038/ni1416
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- Article
HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistance.
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- Nature Communications, 2014, v. 5, n. 8, p. 4602, doi. 10.1038/ncomms5602
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- Article
The phosphatase JKAP/DUSP22 inhibits T-cell receptor signalling and autoimmunity by inactivating Lck.
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- Nature Communications, 2014, v. 5, n. 4, p. 3618, doi. 10.1038/ncomms4618
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- Article
MAP4K Family Kinases and DUSP Family Phosphatases in T-Cell Signaling and Systemic Lupus Erythematosus.
- Published in:
- Cells (2073-4409), 2019, v. 8, n. 11, p. 1433, doi. 10.3390/cells8111433
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- Article
Dual-Specificity Phosphatase 6 Deficiency Attenuates Arterial-Injury-Induced Intimal Hyperplasia in Mice.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 24, p. 17136, doi. 10.3390/ijms242417136
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- Article
Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset Still's disease and may act as an activity marker.
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- BMC Medicine, 2012, v. 10, n. 1, p. 84, doi. 10.1186/1741-7015-10-84
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- Article
Induction of Interferon‐γ and Tissue Inflammation by Overexpression of Eosinophil Cationic Protein in T Cells and Exosomes.
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- Arthritis & Rheumatology, 2022, v. 74, n. 1, p. 92, doi. 10.1002/art.41920
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- Article