Works by Tan, Kai Sen

Results: 37

In Vitro Model of Fully Differentiated Human Nasal Epithelial Cells Infected With Rhinovirus Reveals Epithelium-Initiated Immune Responses.

Published in:

2018

By:

Kai Sen Tan;
Hsiao Hui Ong;
Yan Yan;
Jing Liu;
Chunwei Li;
Yew Kwang Ong;
Kim Thye Thong;
Hyung Won Choi;
De-Yun Wang;
Vincent T. Chow;
Tan, Kai Sen;
Ong, Hsiao Hui;
Yan, Yan;
Liu, Jing;
Li, Chunwei;
Ong, Yew Kwang;
Thong, Kim Thye;
Choi, Hyung Won;
Wang, De-Yun;
Chow, Vincent T

Publication type:

journal article

Generation of self-replicating airway organoids from the cave nectar bat Eonycteris spelaea as a model system for studying host–pathogen interactions in the bat airway epithelium.

Published in:

Emerging Microbes & Infections, 2023, v. 12, n. 1, p. 1, doi. 10.1080/22221751.2022.2148561

By:

Chan, Louisa L.Y.;
Gamage, Akshamal M.;
Tan, Chee Wah;
Tan, Kai Sen;
Liu, Jing;
Tay, Douglas Jie Wen;
Foo, Randy Jee Hiang;
Rénia, Laurent;
Wang, De Yun;
Wang, Lin-Fa

Publication type:

Article

Uncovering Novel Viral Innate Immune Evasion Strategies: What Has SARS-CoV-2 Taught Us?

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.844447

By:

Tay, Douglas Jie Wen;
Lew, Zhe Zhang Ryan;
Chu, Justin Jang Hann;
Tan, Kai Sen

Publication type:

Article

A Co-culture Model of PBMC and Stem Cell Derived Human Nasal Epithelium Reveals Rapid Activation of NK and Innate T Cells Upon Influenza A Virus Infection of the Nasal Epithelium.

Published in:

Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.02514

By:

Luukkainen, Annika;
Puan, Kia Joo;
Yusof, Nurhashikin;
Lee, Bernett;
Tan, Kai Sen;
Liu, Jing;
Yan, Yan;
Toppila-Salmi, Sanna;
Renkonen, Risto;
Chow, Vincent T.;
Rotzschke, Olaf;
Wang, De Yun

Publication type:

Article

An Integrated Analysis of Radial Spoke Head and Outer Dynein Arm Protein Defects and Ciliogenesis Abnormality in Nasal Polyps.

Published in:

Frontiers in Genetics, 2019, v. 10, p. 1, doi. 10.3389/fgene.2019.01083

By:

Zi, Xiao-xue;
Guan, Wei-jie;
Peng, Yang;
Tan, Kai Sen;
Liu, Jing;
He, Ting-ting;
Ong, Yew-kwang;
Thong, Mark;
Shi, Li;
Wang, De-yun

Publication type:

Article

Micro-RNAs in regenerating lungs: an integrative systems biology analysis of murine influenza pneumonia

Published in:

BMC Genomics, 2014, v. 15, n. 1, p. 587, doi. 10.1186/1471-2164-15-587

By:

Kai Sen Tan;
Hyungwon Choi;
Xiaoou Jiang;
Lu Yin;
Ju Ee Seet;
Patzel, Volker;
Engelward, Bevin P;
Chow, Vincent T

Publication type:

Article

Sinus computed tomography predicts clinical response to corticosteroids in chronic rhinosinusitis with nasal polyps.

Published in:

Clinical & Translational Allergy, 2018, v. 8, n. 1, p. N.PAG, doi. 10.1186/s13601-018-0211-1

By:

Hong, Haiyu;
Wang, Dan;
Tan, Kai Sen;
Zheng, Rui;
Chen, Fenghong;
Gao, Wenxiang;
He, Haixin;
Shi, Jianbo;
Fan, Yunping;
Yang, Qintai;
Sun, Yueqi

Publication type:

Article

Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles.

Published in:

PLoS Pathogens, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.ppat.1009130

By:

Gamage, Akshamal M.;
Tan, Kai Sen;
Chan, Wharton O. Y.;
Liu, Jing;
Tan, Chee Wah;
Ong, Yew Kwang;
Thong, Mark;
Andiappan, Anand K.;
Anderson, Danielle E.;
Wang, De Yun;
Wang, Lin-Fa

Publication type:

Article

ACE2 and TMPRSS2 gene expression is reduced acutely in SARS-CoV-2 patients but returns to normal with recovery.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-96279-x

By:

Chen, Vanessa Hui En;
Tay, Joshua K.;
Gurung, Rijan;
Nair, Smeetha;
Tay, Douglas Jie Wen;
Tan, Kai Sen;
Foo, Roger S. Y.;
Tambyah, Paul A.

Publication type:

Article

Absence or mislocalization of DNAH5 is a characteristic marker for motile ciliary abnormality in nasal polyps.

Published in:

2018

By:

Qiu, Qianhui;
Peng, Yang;
Zhu, Zhenchao;
Chen, Zhuo;
Zhang, Chi;
Ong, Hsiao Hui;
Tan, Kai Sen;
Hong, Haiyu;
Yan, Yan;
Huang, Haoqi;
Liu, Jing;
Li, Xianqing;
Nam, H. N.;
Dung, N. T. N.;
Shi, Li;
Yang, Qintai;
Bingle, Colin D.;
Wang, De‐Yun;
Wang, De-Yun

Publication type:

journal article

The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak – an update on the status.

Published in:

Military Medical Research, 2020, v. 7, n. 1, p. 1, doi. 10.1186/s40779-020-00240-0

By:

Guo, Yan-Rong;
Cao, Qing-Dong;
Hong, Zhong-Si;
Tan, Yuan-Yang;
Chen, Shou-Deng;
Jin, Hong-Jun;
Tan, Kai-Sen;
Wang, De-Yun;
Yan, Yan

Publication type:

Article

p63<sup>+</sup>Krt5<sup>+</sup> basal cells are increased in the squamous metaplastic epithelium of patients with radiation-induced chronic Rhinosinusitis.

Published in:

2020

By:

Huang, Hongming;
Tan, Kai Sen;
Zhou, Suizi;
Yuan, Tian;
Liu, Jing;
Ong, Hsiao Hui;
Chen, Qianmin;
Gao, Junxiao;
Xu, Minghong;
Zhu, Zhenchao;
Qiu, Qianhui;
Wang, De Yun

Publication type:

journal article

Tetraspanins: Host Factors in Viral Infections.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 21, p. 11609, doi. 10.3390/ijms222111609

By:

New, ChihSheng;
Lee, Zhao-Yong;
Tan, Kai Sen;
Wong, Amanda Huee-Ping;
Wang, De Yun;
Tran, Thai

Publication type:

Article

Upregulation of cell-surface mucin MUC15 in human nasal epithelial cells upon influenza A virus infection.

Published in:

2019

By:

Chen, Zhuang Gui;
Wang, Zhao Ni;
Yan, Yan;
Liu, Jing;
He, Ting Ting;
Thong, Kim Thye;
Ong, Yew Kwang;
Chow, Vincent T. K.;
Tan, Kai Sen;
Wang, De Yun

Publication type:

journal article

Comparative Transcriptomic and Metagenomic Analyses of Influenza Virus-Infected Nasal Epithelial Cells From Multiple Individuals Reveal Specific Nasal-Initiated Signatures.

Published in:

Frontiers in Microbiology, 2018, p. N.PAG, doi. 10.3389/fmicb.2018.02685

By:

Tan, Kai Sen;
Yan, Yan;
Koh, Wai Ling Hiromi;
Li, Liang;
Choi, Hyungwon;
Tran, Thai;
Sugrue, Richard;
Wang, De Yun;
Chow, Vincent T.

Publication type:

Article

Overexpression of Neutrophil MMP-9 and HIF-1α May Contribute to the Finger-Like Projections Formation and Histo-Pathogenesis in Nasal Inverted Papilloma.

Published in:

Journal of Inflammation Research, 2021, v. 14, p. 2979, doi. 10.2147/JIR.S312605

By:

Li, Tao;
Tan, Kai Sen;
Tu, Yan Yi;
Zhao, Li;
Liu, Jing;
Ong, Hsiao Hui;
Wang, De Yun;
Shi, Li

Publication type:

Article

Induction of IL-25 Expression in Human Nasal Polyp Epithelium by Influenza Virus Infection is Abated by Interferon-Alpha Pretreatment.

Published in:

Journal of Inflammation Research, 2021, v. 14, p. 2769, doi. 10.2147/JIR.S304320

By:

Hong, Haiyu;
Tan, Kai Sen;
Yan, Yan;
Chen, Fenghong;
Ong, Hsiao Hui;
Oo, Yukei;
Liu, Jing;
Ong, Yew Kwang;
Thong, Mark;
Sugrue, Richard;
Chow, Vincent T;
Wang, De Yun

Publication type:

Article

Viral Load of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Respiratory Aerosols Emitted by Patients With Coronavirus Disease 2019 (COVID-19) While Breathing, Talking, and Singing.

Published in:

Clinical Infectious Diseases, 2022, v. 74, n. 10, p. 1722, doi. 10.1093/cid/ciab691

By:

Coleman, Kristen K;
Tay, Douglas Jie Wen;
Tan, Kai Sen;
Ong, Sean Wei Xiang;
Than, The Son;
Koh, Ming Hui;
Chin, Yi Qing;
Nasir, Haziq;
Mak, Tze Minn;
Chu, Justin Jang Hann;
Milton, Donald K;
Chow, Vincent T K;
Tambyah, Paul Anantharajah;
Chen, Mark;
Tham, Kwok Wai

Publication type:

Article

Aberrant localization of FOXJ1 correlates with the disease severity and comorbidities in patients with nasal polyps.

Published in:

Allergy, Asthma & Clinical Immunology, 2018, v. 14, n. 1, p. N.PAG, doi. 10.1186/s13223-018-0296-z

By:

Peng, Yang;
Guan, Wei-jie;
Tan, Kai Sen;
Zhu, Zhenchao;
Chen, Zhuo;
Hong, Haiyu;
Wang, Zhaoni;
Tian, Tengfei;
Zi, Xiaoxue;
Ong, Yew Kwang;
Thong, Mark;
Shi, Li;
Yang, Qintai;
Qiu, Qianhui;
Wang, De-Yun

Publication type:

Article

Distribution and Determinants of Dermatophagoides Mites Sensitization ofAllergic Rhinitis and Allergic Asthma in China.

Published in:

International Archives of Allergy & Immunology, 2019, v. 180, n. 1, p. 17, doi. 10.1159/000499409

By:

Chen, Zhuang-Gui;
Li, Ya-Ting;
Wang, Wei-Hao;
Tan, Kai Sen;
Zheng, Rui;
Yang, Li-Fen;
Guan, Wei-Jie;
Hong, Hai-Yu;
Yang, Qin-Tai

Publication type:

Article

Downregulation and Aberrant Localization of Forkhead Box J1 in Allergic Nasal Mucosa.

Published in:

International Archives of Allergy & Immunology, 2018, v. 176, n. 2, p. 115, doi. 10.1159/000488014

By:

Peng, Yang;
Chen, Zhuo;
Guan, Wei-Jie;
Zhu, Zhenchao;
Tan, Kai Sen;
Hong, Haiyu;
Zi, Xiaoxue;
Zeng, Jie;
Li, Yixuan;
Ong, Yew Kwang;
Thong, Mark;
Shi, Li;
Yang, Qintai;
Qiu, Qianhui ;
Wang, De-Yun

Publication type:

Article

Evaluation of In Vitro and In Vivo Antiviral Activities of Vitamin D for SARS-CoV-2 and Variants.

Published in:

Pharmaceutics, 2023, v. 15, n. 3, p. 925, doi. 10.3390/pharmaceutics15030925

By:

Mok, Chee-Keng;
Ng, Yan Ling;
Ahidjo, Bintou Ahmadou;
Aw, Zhen Qin;
Chen, Huixin;
Wong, Yi Hao;
Lee, Regina Ching Hua;
Loe, Marcus Wing Choy;
Liu, Jing;
Tan, Kai Sen;
Kaur, Parveen;
Wang, De Yun;
Hao, Erwei;
Hou, Xiaotao;
Tan, Yong Wah;
Deng, Jiagang;
Chu, Justin Jang Hann

Publication type:

Article

Insights into Early Recovery from Influenza Pneumonia by Spatial and Temporal Quantification of Putative Lung Regenerating Cells and by Lung Proteomics.

Published in:

Cells (2073-4409), 2019, v. 8, n. 9, p. 975, doi. 10.3390/cells8090975

By:

Ong, Joe Wee Jian;
Tan, Kai Sen;
Ler, Siok Ghee;
Gunaratne, Jayantha;
Choi, Hyungwon;
Seet, Ju Ee;
Chow, Vincent Tak-Kwong

Publication type:

Article

RNA Sequencing of H3N2 Influenza Virus-Infected Human Nasal Epithelial Cells from Multiple Subjects Reveals Molecular Pathways Associated with Tissue Injury and Complications.

Published in:

Cells (2073-4409), 2019, v. 8, n. 9, p. 986, doi. 10.3390/cells8090986

By:

Tan, Kai Sen;
Andiappan, Anand Kumar;
Lee, Bernett;
Yan, Yan;
Liu, Jing;
Tang, See Aik;
Lum, Josephine;
He, Ting Ting;
Ong, Yew Kwang;
Thong, Mark;
Lim, Hui Fang;
Choi, Hyung Won;
Rotzschke, Olaf;
Chow, Vincent T;
Wang, De Yun

Publication type:

Article

Investigating the efficacy of pamidronate, a chemical inhibitor of farnesyl pyrophosphate synthase, in the inhibition of influenza virus infection in vitro and in vivo.

Published in:

Molecular Medicine Reports, 2014, v. 9, n. 1, p. 51, doi. 10.3892/mmr.2013.1750

By:

KAI SEN TAN;
WAI CHIING;
SEET, JUEE;
OLFAT, FARZAD;
ENGELWARD, BEVIN P.;
CHOW, VINCENT T. K.

Publication type:

Article

Motile Ciliary Disorders in Chronic Airway Inflammatory Diseases: Critical Target for Interventions.

Published in:

Current Allergy & Asthma Reports, 2018, v. 18, n. 9, p. 1, doi. 10.1007/s11882-018-0802-x

By:

Guan, Wei-jie;
Peng, Yang;
Zi, Xiao-xue;
Tan, Kai Sen;
He, Ting-ting;
Zhong, Nan-shan;
Wang, De Yun

Publication type:

Article

Vaping and Respiratory Viruses: The End for ENDS?

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2021, v. 64, n. 1, p. 16, doi. 10.1165/rcmb.2020-0501ED

By:

Kai Sen Tan;
De Yun Wang

Publication type:

Article

Differential effects of microRNAs miR‐21, miR‐99 and miR‐145 on lung regeneration and inflammation during recovery from influenza pneumonia.

Published in:

Journal of Medical Virology, 2023, v. 95, n. 12, p. 1, doi. 10.1002/jmv.29286

By:

Ong, Joe Wee Jian;
Tan, Kai Sen;
Lee, Joseph Jing Xian;
Seet, Ju Ee;
Choi, Hyung Won;
Ler, Siok Ghee;
Gunaratne, Jayantha;
Narasaraju, Teluguakula;
Sham, Lok‐To;
Patzel, Volker;
Chow, Vincent T.

Publication type:

Article

Zero Secondary Transmission from Three Traveling COVID-19 Cases in China: A Case for Social Responsibility from the General Public in Stemming the Chain of Transmission.

Published in:

Risk Management & Healthcare Policy, 2022, v. 15, p. 107, doi. 10.2147/RMHP.S328950

By:

Su, Rongfei;
Hu, Yuqi;
Liao, Zhenpeng;
Tan, Kai Sen;
Hong, Haiyu;
Fan, Yunping

Publication type:

Article

Decreased hospital charges and postoperative pain in septoplasty by application of enhanced recovery after surgery.

Published in:

2018

By:

Liao, Zhenpeng;
Liao, Wei;
Tan, Kai Sen;
Sun, Yueqi;
Peng, Aiqing;
Zhu, Yingxian;
He, Haixin;
Yang, Shuowei;
Xu, Guangfu;
Su, Rongfei;
Yao, Jinyu;
Fan, Yunping;
Yang, Qintai;
Hong, Haiyu

Publication type:

journal article

Microarray Assay Reveals Ciliary Abnormalities of the Allergic Nasal Mucosa.

Published in:

American Journal of Rhinology & Allergy, 2020, v. 34, n. 1, p. 50, doi. 10.1177/1945892419871795

By:

Peng, Yang;
Guan, Wei-jie;
Zhu, Zhen-chao;
Tan, Kai Sen;
Chen, Zhuo;
Hong, Hai-yu;
Zi, Xiao-xue;
Andiappan, Anand Kumar;
Shi, Li;
Yang, Qin-tai;
Wang, De-Yun;
Qiu, Qian-hui

Publication type:

Article

Mucus composition abnormalities in sinonasal mucosa of chronic rhinosinusitis with and without nasal polyps.

Published in:

Inflammation, 2021, v. 44, n. 5, p. 1937, doi. 10.1007/s10753-021-01471-6

By:

Tu, Yanyi;
Liu, Jing;
Li, Tao;
Zhou, Xiangmin;
Tan, Kai Sen;
Ong, Hsiao Hui;
Sun, Kaiyue;
Ouyang, Yi;
Liang, Xu;
Ong, Yew Kwang;
Thong, Mark;
Shi, Li;
Wang, De-Yun

Publication type:

Article

Transcriptomics of rhinovirus persistence reveals sustained expression of RIG‐I and interferon‐stimulated genes in nasal epithelial cells in vitro.

Published in:

Allergy, 2022, v. 77, n. 9, p. 2778, doi. 10.1111/all.15280

By:

Ong, Hsiao Hui;
Andiappan, Anand Kumar;
Duan, Kaibo;
Lum, Josephine;
Liu, Jing;
Tan, Kai Sen;
Howland, Shanshan;
Lee, Bernett;
Ong, Yew Kwang;
Thong, Mark;
Chow, Vincent T.;
Wang, De‐Yun

Publication type:

Article

Corrigendum: Role of yes‐associated protein in interleukin‐13 induced nasal remodeling of chronic rhinosinusitis with nasal polyps.

Published in:

Allergy, 2022, v. 77, n. 2, p. 713, doi. 10.1111/all.15172

By:

Yuan, Tian;
Zheng, Rui;
Liu, Jing;
Tan, Kai Sen;
Huang, Zhi‐qun;
Zhou, Xiang‐Min;
Zi, Xiao‐xue;
Qiu, Hui‐jun;
Wang, Xin‐yue;
Wang, Wei‐hao;
Deng, Hui‐yi;
Chen, Yu‐bin;
Kong, Wei‐feng;
Wu, Qing‐wu;
Huang, Ying;
Ong, Hsiao Hui;
Huang, Xue‐kun;
Chen, Zhuang‐gui;
Wang, De‐Yun;
Yang, Qin‐Tai

Publication type:

Article

Role of yes‐associated protein in interleukin‐13 induced nasal remodeling of chronic rhinosinusitis with nasal polyps.

Published in:

Allergy, 2021, v. 76, n. 2, p. 600, doi. 10.1111/all.14699

By:

Yuan, Tian;
Zheng, Rui;
Liu, Jing;
Tan, Kai Sen;
Huang, Zhi‐qun;
Zhou, Xiang‐Min;
Zi, Xiao‐xue;
Qiu, Hui‐jun;
Wang, Xin‐yue;
Wang, Wei‐hao;
Deng, Hui‐yi;
Chen, Yu‐bin;
Kong, Wei‐feng;
Wu, Qing‐wu;
Huang, Ying;
Ong, Hsiao Hui;
Huang, Xue‐kun;
Chen, Zhuang‐gui;
Wang, De‐Yun;
Yang, Qin‐Tai

Publication type:

Article

Hypoxia‐induced factor‐1α induces NLRP3 expression by M1 macrophages in noneosinophilic chronic rhinosinusitis with nasal polyps.

Published in:

Allergy, 2021, v. 76, n. 2, p. 582, doi. 10.1111/all.14571

By:

Zhong, Bing;
Du, Jintao;
Liu, Feng;
Liu, Yafeng;
Liu, Shixi;
Zhang, Jie;
Lin, Ping;
Zhou, Jiao;
Liu, Jing;
Ong, Hsiao Hui;
Tan, Kai Sen;
Wang, Deyun;
Ba, Luo

Publication type:

Article

Type 2‐low asthma phenotypes by integration of sputum transcriptomics and serum proteomics.

Published in:

Allergy, 2021, v. 76, n. 1, p. 380, doi. 10.1111/all.14573

By:

Zounemat Kermani, Nazanin;
Saqi, Mansoor;
Agapow, Paul;
Pavlidis, Stelios;
Kuo, Chihhsi;
Tan, Kai Sen;
Mumby, Sharon;
Sun, Kai;
Loza, Matthew;
Baribaud, Frederic;
Sousa, Ana R.;
Riley, John;
Wheelock, Asa M.;
Wheelock, Craig E.;
De Meulder, Bertrand;
Schofield, Jim;
Sánchez‐Ovando, Stephany;
Simpson, Jodie Louise;
Baines, Katherine Joanne;
Wark, Peter A.

Publication type:

Article