Works by Tal-Singer, Ruth

Results: 109
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    Quantification of Lung PET Images: Challenges and Opportunities.

    Published in:
    Journal of Nuclear Medicine, 2017, v. 58, n. 2, p. 201, doi. 10.2967/jnumed.116.184796
    By:
    • Chen, Delphine L.;
    • Cheriyan, Joseph;
    • Chilvers, Edwin R.;
    • Choudhury, Gourab;
    • Coello, Christopher;
    • Connell, Martin;
    • Fisk, Marie;
    • Groves, Ashley M.;
    • Gunn, Roger N.;
    • Holman, Beverley F.;
    • Hutton, Brian F.;
    • Lee, Sarah;
    • MacNee, William;
    • Mohan, Divya;
    • Parr, David;
    • Subramanian, Deepak;
    • Tal-Singer, Ruth;
    • Thielemans, Kris;
    • van Beek, Edwin J. R.;
    • Vass, Laurence
    Publication type:
    Article
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    Genetic Association and Risk Scores in a Chronic Obstructive Pulmonary Disease Meta-analysis of 16,707 Subjects.

    Published in:
    American Journal of Respiratory Cell & Molecular Biology, 2017, v. 57, n. 1, p. 35, doi. 10.1165/rcmb.2016-0331OC
    By:
    • Busch, Robert;
    • Hobbs, Brian D.;
    • Jin Zhou;
    • Castaldi, Peter J.;
    • McGeachie, Michael J.;
    • Hardin, Megan E.;
    • Hawrylkiewicz, Iwona;
    • Sliwinski, Pawel;
    • Jae-Joon Yim;
    • Woo Jin Kim;
    • Kim, Deog K.;
    • Agusti, Alvar;
    • Make, Barry J.;
    • Crapo, James D.;
    • Calverley, Peter M.;
    • Donner, Claudio F.;
    • Lomas, David A.;
    • Wouters, Emiel F.;
    • Vestbo, Jørgen;
    • Tal-Singer, Ruth
    Publication type:
    Article
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    Common Genetic Variants Associated with Resting Oxygenation in Chronic Obstructive Pulmonary Disease.

    Published in:
    American Journal of Respiratory Cell & Molecular Biology, 2014, v. 51, n. 5, p. 678, doi. 10.1165/rcmb.2014-0135OC
    By:
    • McDonald, Merry-Lynn N.;
    • Cho, Michael H.;
    • Sørheim, Inga-Cecilie;
    • Lutz, Sharon M.;
    • Castaldi, Peter J.;
    • Lomas, David A.;
    • Coxson, Harvey O.;
    • Edwards, Lisa D.;
    • MacNee, William;
    • Vestbo, Jørgen;
    • Yates, Julie C.;
    • Agusti, Alvar;
    • Calverley, Peter M. A.;
    • Celli, Bartolome;
    • Crim, Courtney;
    • Rennard, Stephen I.;
    • Wouters, Emiel F. M.;
    • Bakke, Per;
    • Tal-Singer, Ruth;
    • Miller, Bruce E.
    Publication type:
    Article
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    The Use of Computed Tomography Densitometry for the Assessment of Emphysema in Clinical Trials: A Position Paper from the Fleischner Society.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2025, v. 211, n. 5, p. 709, doi. 10.1164/rccm.202410-2012SO
    By:
    • San José Estépar, Raúl;
    • Barr, R. Graham;
    • Fain, Sean B.;
    • Grenier, Philippe A.;
    • Hoffman, Eric A.;
    • Humphries, Stephen M.;
    • Kirby, Miranda;
    • Obuchowski, Nancy;
    • Ryerson, Christopher J.;
    • Seo, Joon Beom;
    • Tal-Singer, Ruth;
    • Ash, Samuel Y.;
    • Bankier, Alexander A.;
    • Crapo, James;
    • Han, MeiLan K.;
    • Kellermeyer, Liz;
    • Goldin, Jonathan;
    • McCollough, Cynthia H.;
    • Newell Jr., John D.;
    • Miller, Bruce E.
    Publication type:
    Article
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    An Update on Outcomes for COPD Pharmacological Trials: A COPD Investigators Report - Reassessment of the 2008 American Thoracic Society/European Respiratory Society Statement on Outcomes for COPD Pharmacological Trials.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2023, v. 208, n. 4, p. 374, doi. 10.1164/rccm.202303-0400SO
    By:
    • Cazzola, Mario;
    • Rogliani, Paola;
    • Barnes, Peter J.;
    • Blasi, Francesco;
    • Celli, Bartolome;
    • Hanania, Nicola A.;
    • Martinez, Fernando J.;
    • Miller, Bruce E.;
    • Miravitlles, Marc;
    • Page, Clive P.;
    • Tal-Singer, Ruth;
    • Matera, Maria Gabriella
    Publication type:
    Article
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    Inflammatory Endotype-associated Airway Microbiome in Chronic Obstructive Pulmonary Disease Clinical Stability and Exacerbations: A Multicohort Longitudinal Analysis.

    Published in:
    2021
    By:
    • Zhang Wang;
    • Locantore, Nicholas;
    • Haldar, Koirobi;
    • Ramsheh, Mohammadali Yavari;
    • Beech, Augusta S.;
    • Wei Ma;
    • Brown, James R.;
    • Tal-Singer, Ruth;
    • Barer, Michael R.;
    • Bafadhel, Mona;
    • Donaldson, Gavin C.;
    • Wedzicha, Jadwiga A.;
    • Singh, Dave;
    • Wilkinson, Tom M. A.;
    • Miller, Bruce E.;
    • Brightling, Christopher E.;
    • Wang, Zhang;
    • Ma, Wei
    Publication type:
    journal article
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    Blood Eosinophil Counts in Clinical Trials for Chronic Obstructive Pulmonary Disease.

    Published in:
    2020
    By:
    • Singh, Dave;
    • Bafadhel, Mona;
    • Brightling, Christopher E.;
    • Sciurba, Frank C.;
    • Curtis, Jeffrey L.;
    • Martinez, Fernando J.;
    • Pasquale, Cara B.;
    • Merrill, Debora D.;
    • Metzdorf, Norbert;
    • Petruzzelli, Stefano;
    • Tal-Singer, Ruth;
    • Compton, Christopher;
    • Rennard, Stephen;
    • Martin, Ubaldo J.;
    • COPD Foundation Eosinophil Working Group
    Publication type:
    journal article
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    A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2015, v. 192, n. 5, p. 559, doi. 10.1164/rccm.201501-0148OC
    By:
    • Cho, Michael H.;
    • Castaldi, Peter J.;
    • Hersh, Craig P.;
    • Hobbs, Brian D.;
    • Barr, R. Graham;
    • Tal-Singer, Ruth;
    • Bakke, Per;
    • Gulsvik, Amund;
    • Estépar, Raú San José;
    • Van Beek, Edwin J. R.;
    • Coxson, Harvey O.;
    • Lynch, David A.;
    • Washko, George R.;
    • Laird, Nan M.;
    • Crapo, James D.;
    • Beaty, Terri H.;
    • Silverman, Edwin K.
    Publication type:
    Article
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    A Genome-wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2015, v. 192, n. 5, p. E1, doi. 10.1164/rccm.201501-0148oc
    By:
    • Cho, Michael H.;
    • Castaldi, Peter J.;
    • Hersh, Craig P.;
    • Hobbs, Brian D.;
    • Barr, R. Graham;
    • Tal-Singer, Ruth;
    • Bakke, Per;
    • Gulsvik, Amund;
    • Estépar, Raúl San José;
    • Van Beek, Edwin;
    • Coxson, Harvey O.;
    • Lynch, David A.;
    • Washko, George R.;
    • Laird, Nan M.;
    • Crapo, James D.;
    • Beaty, Terri H.;
    • Silverman, Edwin K.
    Publication type:
    Article
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    The sputum microbiome is distinct between COPD and health, independent of smoking history.

    Published in:
    2020
    By:
    • Haldar, Koirobi;
    • George, Leena;
    • Wang, Zhang;
    • Mistry, Vijay;
    • Ramsheh, Mohammadali Yavari;
    • Free, Robert C.;
    • John, Catherine;
    • Reeve, Nicola F.;
    • Miller, Bruce E.;
    • Tal-Singer, Ruth;
    • Webb, Adam J.;
    • Brookes, Anthony J.;
    • Tobin, Martin D.;
    • Singh, Dave;
    • Donaldson, Gavin C.;
    • Wedzicha, Jadwiga A.;
    • Brown, James R.;
    • Barer, Michael R.;
    • Brightling, Christopher E.
    Publication type:
    journal article
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    CXCR2 antagonist for patients with chronic obstructive pulmonary disease with chronic mucus hypersecretion: a phase 2b trial.

    Published in:
    2020
    By:
    • Lazaar, Aili L.;
    • Miller, Bruce E.;
    • Donald, Alison C.;
    • Keeley, Thomas;
    • Ambery, Claire;
    • Russell, John;
    • Watz, Henrik;
    • Tal-Singer, Ruth;
    • for 205724 Investigators;
    • Bardin, Philip;
    • Bremner, Peter;
    • Langton, David;
    • Southcott, Anne-Marie;
    • Thomas, Paul S.;
    • Wheatley, John;
    • Chapman, Kenneth R.;
    • Ferguson, Murdo;
    • Homik, Lawrence A.;
    • Maltais, Francois;
    • Pek, Bonavuth
    Publication type:
    journal article
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    Heme metabolism genes Downregulated in COPD Cachexia.

    Published in:
    2020
    By:
    • Wilson, Ava C.;
    • Kumar, Preeti L.;
    • Lee, Sool;
    • Parker, Margaret M.;
    • Arora, Itika;
    • Morrow, Jarrett D.;
    • Wouters, Emiel F. M.;
    • Casaburi, Richard;
    • Rennard, Stephen I.;
    • Lomas, David A.;
    • Agusti, Alvar;
    • Tal-Singer, Ruth;
    • Dransfield, Mark T.;
    • Wells, J. Michael;
    • Bhatt, Surya P.;
    • Washko, George;
    • Thannickal, Victor J.;
    • Tiwari, Hemant K.;
    • Hersh, Craig P.;
    • Castaldi, Peter J.
    Publication type:
    journal article
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    Genetic variation in genes regulating skeletal muscle regeneration and tissue remodelling associated with weight loss in chronic obstructive pulmonary disease.

    Published in:
    Journal of Cachexia, Sarcopenia & Muscle, 2021, v. 12, n. 6, p. 1803, doi. 10.1002/jcsm.12782
    By:
    • Lakshman Kumar, Preeti;
    • Wilson, Ava C.;
    • Rocco, Alison;
    • Cho, Michael H.;
    • Wan, Emily;
    • Hobbs, Brian D.;
    • Washko, George R.;
    • Ortega, Victor E.;
    • Christenson, Stephanie A.;
    • Li, Xingnan;
    • Wells, J. Michael;
    • Bhatt, Surya P.;
    • DeMeo, Dawn L.;
    • Lutz, Sharon M.;
    • Rossiter, Harry;
    • Casaburi, Richard;
    • Rennard, Stephen I.;
    • Lomas, David A.;
    • Labaki, Wassim W.;
    • Tal‐Singer, Ruth
    Publication type:
    Article
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    The p38 mitogen activated protein kinase inhibitor losmapimod in chronic obstructive pulmonary disease patients with systemic inflammation, stratified by fibrinogen: A randomised double-blind placebo-controlled trial.

    Published in:
    PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0194197
    By:
    • Fisk, Marie;
    • Cheriyan, Joseph;
    • Mohan, Divya;
    • Forman, Julia;
    • Mäki-Petäjä, Kaisa M.;
    • McEniery, Carmel M.;
    • Fuld, Jonathan;
    • Rudd, James H. F.;
    • Hopkinson, Nicholas S.;
    • Lomas, David A.;
    • Cockcroft, John R.;
    • Tal-Singer, Ruth;
    • Polkey, Michael I.;
    • Wilkinson, Ian B.
    Publication type:
    Article
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    An Aberrant Leukotriene A<sub>4</sub> Hydrolase-Proline-Glycine-Proline Pathway in the Pathogenesis of Chronic Obstructive Pulmonary Disease.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2014, v. 190, n. 1, p. 51, doi. 10.1164/rccm.201401-0145OC
    By:
    • Wells, J. Michael;
    • O'Reilly, Philip J.;
    • Szul, Tomasz;
    • Sullivan, Daniel I.;
    • Handley, Guy;
    • Garrett, Chris;
    • McNicholas, Carmel M.;
    • Roda, Mojtaba Abdul;
    • Miller, Bruce E.;
    • Tal-Singer, Ruth;
    • Gaggar, Amit;
    • Rennard, Stephen I.;
    • Jackson, Patricia L.;
    • Blalock, J. Edwin
    Publication type:
    Article
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    Should we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study team.

    Published in:
    2014
    By:
    • Vestbo, Jørgen;
    • Agusti, Alvar;
    • Wouters, Emiel F M;
    • Bakke, Per;
    • Calverley, Peter M A;
    • Celli, Bartolome;
    • Coxson, Harvey;
    • Crim, Courtney;
    • Edwards, Lisa D;
    • Locantore, Nicholas;
    • Lomas, David A;
    • Macnee, William;
    • Miller, Bruce;
    • Rennard, Stephen I;
    • Silverman, Edwin K;
    • Yates, Julie C;
    • Tal-Singer, Ruth;
    • Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints Study Investigators
    Publication type:
    journal article
    41

    Should We View Chronic Obstructive Pulmonary Disease Differently after ECLIPSE?

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2014, v. 189, n. 9, p. 1022, doi. 10.1164/rccm.201311-2006PP
    By:
    • Vestbo, Jørgen;
    • Agusti, Alvar;
    • Wouters, Emiel F. M.;
    • Bakke, Per;
    • Calverley, Peter M. A.;
    • Celli, Bartolome;
    • Coxson, Harvey;
    • Crim, Courtney;
    • Edwards, Lisa D.;
    • Locantore, Nicholas;
    • Lomas, David A.;
    • MacNee, William;
    • Miller, Bruce;
    • Rennard, Stephen I.;
    • Silverman, Edwin K.;
    • Yates, Julie C.;
    • Tal-Singer, Ruth
    Publication type:
    Article
    42

    Systemic Soluble Receptor for Advanced Glycation Endproducts Is a Biomarker of Emphysema and Associated with AGER Genetic Variants in Patients with Chronic Obstructive Pulmonary Disease.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2013, v. 188, n. 8, p. 948, doi. 10.1164/rccm.201302-0247OC
    By:
    • Donavan T. Cheng;
    • Deog Kyeom Kim;
    • Cockayne, Debra A.;
    • Belousov, Anton;
    • Bitter, Hans;
    • Cho, Michael H.;
    • Duvoix, Annelyse;
    • Edwards, Lisa D.;
    • Lomas, David A.;
    • Miller, Bruce E.;
    • Reynaert, Niki;
    • Tal-Singer, Ruth;
    • Wouters, Emiel F. M.;
    • Agusti, Alvar;
    • Fabbri, Leonardo M.;
    • Rames, Alex;
    • Visvanathan, Sudha;
    • Rennard, Stephen I.;
    • Jones, Paul;
    • Parmar, Harsukh
    Publication type:
    Article
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    Six-minute-walk test in chronic obstructive pulmonary disease: minimal clinically important difference for death or hospitalization.

    Published in:
    2013
    By:
    • Polkey, Michael I;
    • Spruit, Martijn A;
    • Edwards, Lisa D;
    • Watkins, Michael L;
    • Pinto-Plata, Victor;
    • Vestbo, Jørgen;
    • Calverley, Peter M A;
    • Tal-Singer, Ruth;
    • Agustí, Alvar;
    • Bakke, Per S;
    • Coxson, Harvey O;
    • Lomas, David A;
    • Macnee, William;
    • Rennard, Stephen;
    • Silverman, Edwin K;
    • Miller, Bruce E;
    • Crim, Courtney;
    • Yates, Julie;
    • Wouters, Emiel F M;
    • Celli, Bartolome
    Publication type:
    journal article
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    Six-Minute-Walk Test in Chronic Obstructive Pulmonary Disease.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2013, v. 187, n. 4, p. 382, doi. 10.1164/rccm.201209-1596oc
    By:
    • Polkey, Michael I.;
    • Spruit, Martijn A.;
    • Edwards, Lisa D.;
    • Watkins, Michael L.;
    • Pinto-Plata, Victor;
    • Vestbo, Jørgen;
    • Calverley, Peter M. A.;
    • Tal-Singer, Ruth;
    • Agustí, Alvar;
    • Bakke, Per S.;
    • Coxson, Harvey O.;
    • Lomas, David A.;
    • MacNee, William;
    • Rennard, Stephen;
    • Silverman, Edwin K.;
    • Miller, Bruce E.;
    • Crim, Courtney;
    • Yates, Julie;
    • Wouters, Emiel F. M.;
    • Celli, Bartolome
    Publication type:
    Article
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    Inflammatory Biomarkers Improve Clinical Prediction of Mortality in Chronic Obstructive Pulmonary Disease.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2012, v. 185, n. 10, p. 1065, doi. 10.1164/rccm.201110-1792oc
    By:
    • Celli, Bartolome R.;
    • Locantore, Nicholas;
    • Yates, Julie;
    • Tal-Singer, Ruth;
    • Miller, Bruce E.;
    • Bakke, Per;
    • Calverley, Peter;
    • Coxson, Harvey;
    • Crim, Courtney;
    • Edwards, Lisa D.;
    • Lomas, David A.;
    • Duvoix, Annelyse;
    • MacNee, William;
    • Rennard, Stephen;
    • Silverman, Edwin;
    • Vestbo, Jørgen;
    • Wouters, Emiel;
    • Agust, Alvar
    Publication type:
    Article
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    Evaluating the Role of Inflammation in Chronic Airways Disease: The ERICA Study.

    Published in:
    COPD: Journal of Chronic Obstructive Pulmonary Disease, 2014, v. 11, n. 5, p. 552, doi. 10.3109/15412555.2014.898031
    By:
    • Mohan, Divya;
    • Gale, Nichola S.;
    • McEniery, Carmel M.;
    • Bolton, Charlotte E.;
    • Cockcroft, John R.;
    • MacNee, William;
    • Fuld, Jonathan;
    • Lomas, David A.;
    • Calverley, Peter M. A.;
    • Shale, Dennis J.;
    • Miller, Bruce E.;
    • Wilkinson, Ian B.;
    • Tal-Singer, Ruth;
    • Polkey, Michael I.
    Publication type:
    Article
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    The COPD Biomarker Qualification Consortium (CBQC).

    Published in:
    COPD: Journal of Chronic Obstructive Pulmonary Disease, 2013, v. 10, n. 3, p. 367, doi. 10.3109/15412555.2012.752807
    By:
    • Casaburi, Richard;
    • Celli, Bartolome;
    • Crapo, James;
    • Criner, Gerard;
    • Croxton, Thomas;
    • Gaw, Alasdair;
    • Jones, Paul;
    • Kline-Leidy, Nancy;
    • Lomas, David A.;
    • Merrill, Debora;
    • Polkey, Michael;
    • Rennard, Stephen;
    • Sciurba, Frank;
    • Tal-Singer, Ruth;
    • Stockley, Robert;
    • Turino, Gerry;
    • Vestbo, Jorgen;
    • Walsh, John
    Publication type:
    Article
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