Works by Takimoto, Chris

Results: 32

Maximum tolerated dose: clinical endpoint for a bygone era?

Published in:

2009

By:

Takimoto, Chris;
Takimoto, Chris H

Publication type:

journal article

A phase I pharmacokinetic study of bexarotene with paclitaxel and carboplatin in patients with advanced non-small cell lung cancer (NSCLC).

Published in:

2012

By:

Rodon, Jordi;
Jacobs, Charlotte;
Chu, Quincy;
Rowinsky, Eric;
Lopez-Anaya, Arturo;
Takimoto, Chris;
Wakelee, Heather

Publication type:

Report

The effect of bexarotene on atorvastatin pharmacokinetics: results from a phase I trial of bexarotene plus chemotherapy in patients with advanced non-small cell lung cancer.

Published in:

2012

By:

Wakelee, Heather;
Takimoto, Chris;
Lopez-Anaya, Arturo;
Chu, Quincy;
Middleton, Gary;
Dunlop, David;
Ramlau, Rodryg;
Leighl, Natasha;
Rowinsky, Eric;
Hao, Desiree;
Zatloukal, Petr;
Jacobs, Charlotte;
Rodon, Jordi

Publication type:

Report

Dose-escalating and pharmacological study of bortezomib in adult cancer patients with impaired renal function: a National Cancer Institute Organ Dysfunction Working Group Study.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1439, doi. 10.1007/s00280-011-1637-5

By:

Leal, Ticiana;
Remick, Scot;
Takimoto, Chris;
Ramanathan, Ramesh;
Davies, Angela;
Egorin, Merrill;
Hamilton, Anne;
LoRusso, Patricia;
Shibata, Stephen;
Lenz, Heinz-Josef;
Mier, James;
Sarantopoulos, John;
Mani, Sridhar;
Wright, John;
Ivy, S.;
Neuwirth, Rachel;
Moltke, Lisa;
Venkatakrishnan, Karthik;
Mulkerin, Daniel

Publication type:

Article

Tesetaxel, a new oral taxane, in combination with capecitabine: a phase I, dose-escalation study in patients with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1565, doi. 10.1007/s00280-011-1639-3

By:

Saif, Muhammad;
Sarantopoulos, John;
Patnaik, Amita;
Tolcher, Anthony;
Takimoto, Chris;
Beeram, Murali

Publication type:

Article

A pharmacokinetic and safety study of intravenous arsenic trioxide in adult cancer patients with renal impairment.

Published in:

Cancer Chemotherapy & Pharmacology, 2010, v. 66, n. 2, p. 345, doi. 10.1007/s00280-009-1169-4

By:

Sweeney, Christopher J.;
Takimoto, Chris;
Wood, Leslie;
Porter, Jennifer M.;
Tracewell, William G.;
Darwish, Mona;
D’Andrea, Denise M.;
Remick, Scot C.

Publication type:

Article

Phase I and pharmacokinetic study of cisplatin and troxacitabine administered intravenously every 28 days in patients with advanced solid malignancies.

Published in:

Cancer Chemotherapy & Pharmacology, 2009, v. 65, n. 1, p. 167, doi. 10.1007/s00280-009-1020-y

By:

Chia-Chi Lin;
Beeram, Muralidhar;
Rowinsky, Eric K.;
Takimoto, Chris H.;
Ng, Chee M.;
Geyer Jr., Charles E.;
Denis, Louis J.;
De Bono, Johann S.;
Hao, Desiree;
Tolcher, Anthony W.;
Rha, Sun-Young;
Jolivet, Jacques;
Patnaik, Amita

Publication type:

Article

Phase I study of paclitaxel poliglumex administered weekly for patients with advanced solid malignancies.

Published in:

Cancer Chemotherapy & Pharmacology, 2009, v. 64, n. 2, p. 287, doi. 10.1007/s00280-008-0869-5

By:

Mita, Monica;
Mita, Alain;
Sarantopoulos, John;
Takimoto, Chris H.;
Rowinsky, Eric K.;
Romero, Ofelia;
Angiuli, Patrizia;
Allievi, Cecilia;
Eisenfeld, Amy;
Verschraegen, Claire F.

Publication type:

Article

Phase I study of cetuximab, erlotinib, and bevacizumab in patients with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2009, v. 63, n. 6, p. 1065, doi. 10.1007/s00280-008-0811-x

By:

Chia-Chi Lin;
Calvo, Emiliano;
Papadopoulos, Kyriakos P.;
Patnaik, Amita;
Sarantopoulos, John;
Mita, Alain C.;
Preston, Glenn G.;
Mita, Monica M.;
Rodon, Jordi;
Mays, Theresa;
I.-Tien Yeh;
O'Rourke, Pat;
Takimoto, Chris H.;
Dancey, Janet E.;
Chen, Helen;
Tolcher, Anthony W.

Publication type:

Article

Phase 0 clinical trials in oncology: a paradigm shift for early drug development?

Published in:

Cancer Chemotherapy & Pharmacology, 2009, v. 63, n. 4, p. 703, doi. 10.1007/s00280-008-0789-4

By:

Takimoto, Chris

Publication type:

Article

Cantuzumab mertansine in a three-times a week schedule: a phase I and pharmacokinetic study.

Published in:

Cancer Chemotherapy & Pharmacology, 2008, v. 62, n. 5, p. 911, doi. 10.1007/s00280-007-0672-8

By:

Rodon, Jordi;
Garrison, Mitchell;
Hammond, Lisa A.;
de Bono, Johann;
Smith, Lon;
Forero, Leonardo;
Hao, Desirée;
Takimoto, Chris;
Lambert, John M.;
Pandite, Lini;
Howard, Maria;
Hongsheng Xie;
Tolcher, Anthony W.

Publication type:

Article

Safety and anti-tumor activity of sorafenib (Nexavar<sup>®</sup>) in combination with other anti-cancer agents: a review of clinical trials.

Published in:

Cancer Chemotherapy & Pharmacology, 2008, v. 61, n. 4, p. 535, doi. 10.1007/s00280-007-0639-9

By:

Takimoto, Chris;
Awada, Ahmad

Publication type:

Article

A phase II, pharmacokinetic, and biologic study of semaxanib and thalidomide in patients with metastatic melanoma.

Published in:

Cancer Chemotherapy & Pharmacology, 2007, v. 59, n. 2, p. 165, doi. 10.1007/s00280-006-0255-0

By:

Mita, Monica M.;
Rowinsky, Eric K.;
Forero, Leonardo;
Eckhart, S. Gail;
Izbicka, Elzbieta;
Weiss, Geoffrey R.;
Beeram, Muralidhar;
Mita, Alain C.;
de Bono, Johann S.;
Tolcher, Anthony W.;
Hammond, Lisa A.;
Simmons, Paul;
Berg, Kristin;
Takimoto, Chris;
Patnaik, Amita

Publication type:

Article

A phase I and pharmacologic study of weekly gemcitabine in combination with infusional 5-fluorodeoxyuridine and oral calcium leucovorin.

Published in:

Cancer Chemotherapy & Pharmacology, 2003, v. 52, n. 6, p. 487, doi. 10.1007/s00280-003-0698-5

By:

Grem, Jean L.;
Quinn, Mary G.;
Keith, Bruce;
Monahan, Brian P.;
Hamilton, J. Michael;
Xu, Yan;
Harold, Nancy;
Nguyen, Dat;
Takimoto, Chris H.;
Rowedder, Anthony;
Pang, Janet;
Morrison, Geraldine;
Chen, Alice

Publication type:

Article

A phase I study of 9-aminocamptothecin as a colloidal dispersion formulation given as a fortnightly 72-h infusion.

Published in:

Cancer Chemotherapy & Pharmacology, 2003, v. 52, n. 4, p. 333, doi. 10.1007/s00280-003-0657-1

By:

Leguizamo, Jorge;
Quinn, Mary;
Takimoto, Chris H.;
Liang, Michael D.;
Ismail, Abdel-Salam Attia;
Pang, Janet;
Dahut, William;
Grem, Jean L.

Publication type:

Article

A phase I and pharmacologic study of 9-aminocamptothecin administered as a 120-h infusion weekly to adult cancer patients.

Published in:

2001

By:

Thomas, Rebecca R.;
Dahut, William;
Harold, Nancy;
Grem, Jean L.;
Monahan, Brian P.;
Liang, Michael;
Band, Roger A.;
Cottrell, Jeff;
Llorens, Victor;
Smith, Judith A.;
Corse, William;
Arbuck, Susan G.;
Wright, John;
Chen, Alice P.;
Shapiro, Jeremy D.;
Hamilton, Michael J.;
Allegra, Carmen J.;
Takimoto, Chris H.;
Thomas, R R;
Dahut, W

Publication type:

journal article

Human plasma carboxylesterase and butyrylcholinesterase enzyme activity: correlations with SN-38 pharmacokinetics during a prolonged infusion of irinotecan.

Published in:

2001

By:

Guemei, Aida A.;
Cottrell, Jeff;
Band, Roger;
Hehman, Hilary;
Prudhomme, Mike;
Pavlov, Michael V.;
Grem, Jean L.;
Ismail, Abdel Salam;
Bowen, Donnell;
Taylor, Robert E.;
Takimoto, Chris H.;
Guemei, A A;
Cottrell, J;
Band, R;
Hehman, H;
Prudhomme, M;
Pavlov, M V;
Grem, J L;
Ismail, A S;
Bowen, D

Publication type:

journal article

Pharmacokinetics and pharmacodynamic effects of 5-fluorouracil given as a one-hour intravenous infusion.

Published in:

2001

By:

Grem, Jean L.;
Quinn, Mary;
Ismail, Abdel;
Takimoto, Chris H.;
Lush, Richard;
Liewehr, David J.;
Steinberg, Seth M.;
Balis, Frank M.;
Chen, Alice P.;
Monahan, Brian P.;
Harold, Nancy;
Corse, William;
Pang, Janet;
Murphy, Robert F.;
Allegra, Carmen J.;
Hamilton, Michael J.;
Grem, J L;
Quinn, M;
Ismail, A S;
Takimoto, C H

Publication type:

journal article

Metabolism of patupilone in patients with advanced solid tumor malignancies.

Published in:

Investigational New Drugs, 2013, v. 31, n. 3, p. 605, doi. 10.1007/s10637-012-9838-2

By:

Kelly, Kevin;
Zollinger, Markus;
Lozac'h, Frédéric;
Tan, Eugene;
Mita, Alain;
Waldmeier, Felix;
Urban, Patrick;
Anand, Suraj;
Wang, Yanfeng;
Swart, Piet;
Takimoto, Chris;
Mita, Monica

Publication type:

Article

Phase 2 study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 (CCL2), in metastatic castration-resistant prostate cancer.

Published in:

Investigational New Drugs, 2013, v. 31, n. 3, p. 760, doi. 10.1007/s10637-012-9869-8

By:

Pienta, Kenneth;
Machiels, Jean-Pascal;
Schrijvers, Dirk;
Alekseev, Boris;
Shkolnik, Mikhail;
Crabb, Simon;
Li, Susan;
Seetharam, Shobha;
Puchalski, Thomas;
Takimoto, Chris;
Elsayed, Yusri;
Dawkins, Fitzroy;
Bono, Johann

Publication type:

Article

A phase II clinical and pharmacokinetic study of intravenous exatecan mesylate (DX-8951f) in patients with untreated metastatic gastric cancer.

Published in:

Investigational New Drugs, 2005, v. 23, n. 5, p. 479, doi. 10.1007/s10637-005-2907-z

By:

Jaffer A. Ajani;
Chris Takimoto;
Carlos R. Becerra;
Alejandro Silva;
Luis Baez;
Allen Cohn;
Pierre Major;
Makio Kamida;
Kevie Feit;
Robert De Jager

Publication type:

Article

Utilizing pharmacokinetics/pharmacodynamics modeling to simultaneously examine free CCL2, total CCL2 and carlumab (CNTO 888) concentration time data.

Published in:

Journal of Clinical Pharmacology, 2013, v. 53, n. 10, p. 1020, doi. 10.1002/jcph.140

By:

Fetterly, Gerald J.;
Aras, Urvi;
Meholick, Patricia D.;
Takimoto, Chris;
Seetharam, Shobha;
McIntosh, Thomas;
de Bono, Johann S.;
Sandhu, Shahneen K.;
Tolcher, Anthony;
Davis, Hugh M.;
Zhou, Honghui;
Puchalski, Thomas A.

Publication type:

Article

Population pharmacokinetic analysis of oxaliplatin in adults and children identifies important covariates for dosing.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 495, doi. 10.1007/s00280-014-2667-6

By:

Nikanjam, Mina;
Stewart, Clinton;
Takimoto, Chris;
Synold, Timothy;
Beaty, Orren;
Fouladi, Maryam;
Capparelli, Edmund

Publication type:

Article

Book Review.

Published in:

1999

By:

TAKIMOTO, CHRIS H.

Publication type:

Book Review

Book review.

Published in:

1997

By:

Takimoto, Chris A.

Publication type:

Book Review

Enigma of fluorouracil and levamisole.

Published in:

1995

By:

Takimoto, Chris H.

Publication type:

Editorial

The Clinical Development of 9-Aminocamptothecin.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 922, n. 1, p. 224, doi. 10.1111/j.1749-6632.2000.tb07041.x

By:

TAKIMOTO, CHRIS H.;
THOMAS, REBECCA

Publication type:

Article

9-Aminocamptothecin and Beyond.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 231, doi. 10.1111/j.1749-6632.1996.tb26393.x

By:

POTMESIL, MILAN;
ARBUCK, SUSAN G.;
TAKIMOTO, CHRIS H.;
LIEBES, LEONARD;
HOCHSTER, HOWARD

Publication type:

Article

Clinical Pharmacology of 9-Aminocamptothecin.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 324, doi. 10.1111/j.1749-6632.1996.tb26407.x

By:

TAKIMOTO, CHRIS H.;
DAHUT, WILLIAM;
HAROLD, NANCY;
NAKASHIMA, HAJIME;
LIEBERMAN, RONALD;
LIANG, MICHAEL D.;
ARBUCK, SUSAN G.;
CHEN, ALICE P.;
HAMILTON, J. MICHAEL;
CANTILENA, LOUIS R.;
ALLEGRA, CARMEN J.;
GREM, JEAN L.

Publication type:

Article

Therapeutic Targeting of the Macrophage Immune Checkpoint CD47 in Myeloid Malignancies.

Published in:

Frontiers in Oncology, 2020, v. 9, p. 1, doi. 10.3389/fonc.2019.01380

By:

Chao, Mark P.;
Takimoto, Chris H.;
Feng, Dong Dong;
McKenna, Kelly;
Gip, Phung;
Liu, Jie;
Volkmer, Jens-Peter;
Weissman, Irving L.;
Majeti, Ravindra

Publication type:

Article

Therapeutic Targeting of the Macrophage Immune Checkpoint CD47 in Myeloid Malignancies.

Published in:

Frontiers in Oncology, 2020, v. 10, p. 1, doi. 10.3389/fonc.2019.01380

By:

Chao, Mark P.;
Takimoto, Chris H.;
Feng, Dong Dong;
McKenna, Kelly;
Gibb, Phuong;
Liu, Jie;
Volkmer, Jens-Peter;
Weissman, Irving L.;
Majeti, Ravindra

Publication type:

Article

Two phase I, pharmacokinetic, and pharmacodynamic studies of DFP-10917, a novel nucleoside analog with 14-day and 7-day continuous infusion schedules.

Published in:

Investigational New Drugs, 2019, v. 37, n. 1, p. 76, doi. 10.1007/s10637-018-0602-0

By:

Sankhala, Kamalesh;
Takimoto, Chris H.;
Mita, Alain C.;
Xiong, Henry;
Rodón, Jordi;
Mehrvarz Sarshekeh, Amir;
Burns, K.;
Iizuka, Kenzo;
Kopetz, Scott

Publication type:

Article