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The effect of liver dysfunction on the pharmacokinetic disposition of belinostat and its five metabolites in patients with advanced cancers.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2024, v. 94, n. 2, p. 157, doi. 10.1007/s00280-024-04651-x
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- Publication type:
- Article
A phase I study of AT-101, a BH3 mimetic, in combination with paclitaxel and carboplatin in solid tumors.
- Published in:
- Investigational New Drugs, 2020, v. 38, n. 3, p. 855, doi. 10.1007/s10637-019-00807-2
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- Publication type:
- Article
Dual Src and EGFR inhibition in combination with gemcitabine in advanced pancreatic cancer: phase I results.
- Published in:
- Investigational New Drugs, 2018, v. 36, n. 3, p. 442, doi. 10.1007/s10637-017-0519-z
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- Publication type:
- Article
A randomized phase II study of cediranib alone versus cediranib in combination with dasatinib in docetaxel resistant, castration resistant prostate cancer patients.
- Published in:
- Investigational New Drugs, 2014, v. 32, n. 5, p. 1005, doi. 10.1007/s10637-014-0106-5
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- Publication type:
- Article
A phase I study of AT-101 with cisplatin and etoposide in patients with advanced solid tumors with an expanded cohort in extensive-stage small cell lung cancer.
- Published in:
- Investigational New Drugs, 2014, v. 32, n. 2, p. 295, doi. 10.1007/s10637-013-9999-7
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- Publication type:
- Article
Inhibition of calcineurin combined with dasatinib has direct and indirect anti-leukemia effects against BCR-ABL1<sup>+</sup> leukemia.
- Published in:
- American Journal of Hematology, 2014, v. 89, n. 9, p. 896, doi. 10.1002/ajh.23776
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- Publication type:
- Article
Rethinking Oncologic Treatment Strategies with Interleukin-2.
- Published in:
- Cells (2073-4409), 2023, v. 12, n. 9, p. 1316, doi. 10.3390/cells12091316
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- Publication type:
- Article
Novel antibody reagents for characterization of drug- and tumor microenvironment-induced changes in epithelial-mesenchymal transition and cancer stem cells.
- Published in:
- PLoS ONE, 2018, v. 13, n. 6, p. 1, doi. 10.1371/journal.pone.0199361
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- Publication type:
- Article
KIT as a Therapeutic Target in Metastatic Melanoma.
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- JAMA: Journal of the American Medical Association, 2011, v. 305, n. 22, p. 2327, doi. 10.1001/jama.2011.746
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- Publication type:
- Article
ABTC-0904: targeting glioma stem cells in GBM: a phase 0/II study of hedgehog pathway inhibitor GDC-0449.
- Published in:
- Journal of Neuro-Oncology, 2023, v. 161, n. 1, p. 33, doi. 10.1007/s11060-022-04193-3
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- Publication type:
- Article
NCI-RTOG Translational Program Strategic Guidelines for the Early-Stage Development of Radiosensitizers.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2013, v. 105, n. 1, p. 11, doi. 10.1093/jnci/djs472
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- Publication type:
- Article
Presence of human papillomavirus type-16 and type-18 DNA sequences and their expression in cervical cancers and cell lines from japanese patients.
- Published in:
- International Journal of Cancer, 1986, v. 37, n. 4, p. 499, doi. 10.1002/ijc.2910370405
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- Publication type:
- Article
Preliminary findings on the use of pulsatile machine reperfusion of a placenta to improve the cord blood collection yield including primitive hematopoietic stem cell fractions.
- Published in:
- Transfusion, 2009, v. 49, n. 9, p. 1911, doi. 10.1111/j.1537-2995.2009.02227.x
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- Publication type:
- Article
Analysis of esophagogastric cancer patients enrolled in the National Cancer Institute Cancer Therapy Evaluation Program sponsored phase 1 trials.
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- Gastric Cancer, 2017, v. 20, n. 3, p. 481, doi. 10.1007/s10120-016-0629-x
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- Publication type:
- Article
Tazemetostat for tumors harboring SMARCB1/SMARCA4 or EZH2 alterations: results from NCI-COG pediatric MATCH APEC1621C.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2023, v. 115, n. 11, p. 1355, doi. 10.1093/jnci/djad085
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- Publication type:
- Article
The Exceptional Responders Initiative: Feasibility of a National Cancer Institute Pilot Study.
- Published in:
- 2021
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- Publication type:
- journal article
Protection of hematopoietic stem cells from pemetrexed toxicity by retroviral gene transfer with a mutant dihydrofolate reductase-mutant thymidylate synthase fusion gene.
- Published in:
- Cancer Gene Therapy, 2004, v. 11, n. 12, p. 767, doi. 10.1038/sj.cgt.7700683
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- Publication type:
- Article
Methotrexate selection of long-term culture initiating cells following transduction of CD34<sup>+</sup> cells with a retrovirus containing a mutated human dihydrofolate reductase gene.
- Published in:
- Cancer Gene Therapy, 2002, v. 9, n. 3, p. 308, doi. 10.1038/sj.cgt.7700443
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- Publication type:
- Article
Retroviral transduction of human dihydropyrimidine dehydrogenase cDNA confers resistance to 5-fluorouracil in murine hematopoietic progenitor cells and human CD34<sup>+</sup>-enriched peripheral blood progenitor cells.
- Published in:
- Cancer Gene Therapy, 2001, v. 8, n. 12, p. 966, doi. 10.1038/sj.cgt.7700393
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- Publication type:
- Article
Comparison of methotrexate resistance conferred by a mutated dihydrofolate reductase (DHFR) cDNA in two different retroviral vectors.
- Published in:
- Cancer Gene Therapy, 2000, v. 7, n. 6, p. 910, doi. 10.1038/sj.cgt.7700199
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- Publication type:
- Article
Phase II study of vemurafenib in children and young adults with tumors harboring BRAF V600 mutations: NCI-COG pediatric MATCH trial (APEC1621) Arm G.
- Published in:
- Oncologist, 2024, v. 29, n. 8, p. 723, doi. 10.1093/oncolo/oyae119
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- Publication type:
- Article
Olaparib for childhood tumors harboring defects in DNA damage repair genes: arm H of the NCI-COG Pediatric MATCH trial.
- Published in:
- Oncologist, 2024, v. 29, n. 7, p. 638, doi. 10.1093/oncolo/oyae096
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- Publication type:
- Article
Phase 1 trial of navitoclax and sorafenib in patients with relapsed or refractory solid tumors with hepatocellular carcinoma expansion cohort.
- Published in:
- Investigational New Drugs, 2024, v. 42, n. 1, p. 127, doi. 10.1007/s10637-024-01420-8
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- Publication type:
- Article
Review: Targeting the Hedgehog pathway in cancer.
- Published in:
- Therapeutic Advances in Medical Oncology, 2010, v. 2, n. 4, p. 237, doi. 10.1177/1758834010366430
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- Publication type:
- Article
Population Pharmacokinetics of Z‐Endoxifen in Patients With Advanced Solid Tumors.
- Published in:
- Journal of Clinical Pharmacology, 2022, v. 62, n. 9, p. 1121, doi. 10.1002/jcph.2053
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- Publication type:
- Article
Vismodegib or cixutumumab in combination with standard chemotherapy for patients with extensive-stage small cell lung cancer: A trial of the ECOG-ACRIN Cancer Research Group (E1508).
- Published in:
- 2016
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- Publication type:
- journal article
Pharmacodynamic markers and clinical results from the phase 2 study of the SMAC mimetic birinapant in women with relapsed platinum-resistant or -refractory epithelial ovarian cancer.
- Published in:
- 2016
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- Publication type:
- journal article
Phase 2 study of dasatinib in the treatment of head and neck squamous cell carcinoma.
- Published in:
- Cancer (0008543X), 2011, v. 117, n. 10, p. 2112, doi. 10.1002/cncr.25769
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- Publication type:
- Article
A phase I pharmacokinetic study of belinostat in patients with advanced cancers and varying degrees of liver dysfunction.
- Published in:
- British Journal of Clinical Pharmacology, 2019, v. 85, n. 11, p. 2499, doi. 10.1111/bcp.14054
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- Publication type:
- Article
Perspectives on research activity in the USA on Cancer Precision Medicine.
- Published in:
- Japanese Journal of Clinical Oncology, 2016, v. 46, n. 2, p. 106, doi. 10.1093/jjco/hyv162
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- Publication type:
- Article
Recent innovations in the USA National Cancer Institute-sponsored investigator initiated Phase I and II anticancer drug development.
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- Japanese Journal of Clinical Oncology, 2015, v. 45, n. 11, p. 1001, doi. 10.1093/jjco/hyv144
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- Publication type:
- Article
Precision Oncology with Drugs Targeting the Replication Stress, ATR, and Schlafen 11.
- Published in:
- Cancers, 2021, v. 13, n. 18, p. 4601, doi. 10.3390/cancers13184601
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- Publication type:
- Article
Unmasking BCL-2 Addiction in Synovial Sarcoma by Overcoming Low NOXA.
- Published in:
- Cancers, 2021, v. 13, n. 10, p. 2310, doi. 10.3390/cancers13102310
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- Publication type:
- Article
Novel Apoptosis-Inducing Agents for the Treatment of Cancer, a New Arsenal in the Toolbox.
- Published in:
- Cancers, 2019, v. 11, n. 8, p. 1087, doi. 10.3390/cancers11081087
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- Publication type:
- Article
Breast cancer growth and metastasis: interplay between cancer stem cells, embryonic signaling pathways and epithelial-to-mesenchymal transition.
- Published in:
- 2011
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- Publication type:
- journal article
A Comparative Study of Longitudinal Toxicities of Cytotoxic Drugs, Molecularly Targeted Agents, Immunomodulatory Drugs, and Cancer Vaccines.
- Published in:
- Clinical Pharmacology & Therapeutics, 2019, v. 106, n. 4, p. 803, doi. 10.1002/cpt.1442
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- Publication type:
- Article
A phase I study of obatoclax mesylate, a Bcl-2 antagonist, plus topotecan in solid tumor malignancies.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2010, v. 66, n. 6, p. 1079, doi. 10.1007/s00280-010-1265-5
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- Publication type:
- Article
SMAC Mimetic/IAP Inhibitor Birinapant Enhances Radiosensitivity of Glioblastoma Multiforme.
- Published in:
- Radiation Research, 2021, v. 195, n. 6, p. 549, doi. 10.1667/RADE-20-00171.1
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- Publication type:
- Article
ACTR-14. PHASE I STUDY OF AZD1775 WITH RADIATION THERAPY (RT) AND TEMOZOLOMIDE (TMZ) IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA (GBM) AND EVALUATION OF INTRATUMORAL DRUG DISTRIBUTION (IDD) IN PATIENTS WITH RECURRENT GBM.
- Published in:
- Neuro-Oncology, 2018, v. 20, p. vi13, doi. 10.1093/neuonc/noy148.048
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- Publication type:
- Article
TARGETING GLIOMA INITIATING CELLS IN GBM: ABTC-0904, A RANDOMIZED PHASE 0/II STUDY TARGETING THE SONIC HEDGEHOG-SIGNALING PATHWAY.
- Published in:
- Neuro-Oncology, 2014, v. 16, n. suppl_3, p. iii46, doi. 10.1093/neuonc/nou209.17
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- Publication type:
- Article
Notch1 phenotype and clinical stage progression in non-small cell lung cancer.
- Published in:
- Journal of Hematology & Oncology, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13045-014-0104-2
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- Publication type:
- Article
Potential utility of a longitudinal relative dose intensity of molecularly targeted agents in phase 1 dose‐finding trials.
- Published in:
- Cancer Science, 2018, v. 109, n. 1, p. 207, doi. 10.1111/cas.13436
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- Publication type:
- Article
Drug induced interstitial lung disease in oncology phase I trials.
- Published in:
- Cancer Science, 2016, v. 107, n. 12, p. 1830, doi. 10.1111/cas.13087
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- Publication type:
- Article