Works by Takakusagi, Yoichi

Results: 22

Activation of oxidoreductases by the formation of enzyme assembly.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-41789-9

By:

Ura, Tomoto;
Sakakibara, Nanako;
Hirano, Yu;
Tamada, Taro;
Takakusagi, Yoichi;
Shiraki, Kentaro;
Mikawa, Tsutomu

Publication type:

Article

Design of Nuclear Magnetic Resonance Molecular Probes for Hyperpolarized Bioimaging.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 27, p. 14779, doi. 10.1002/anie.201915718

By:

Kondo, Yohei;
Nonaka, Hiroshi;
Takakusagi, Yoichi;
Sando, Shinsuke

Publication type:

Article

A Screening of a Library of T7 Phage-Displayed Peptide Identifies E2F-4 as an Etoposide-Binding Protein.

Published in:

Molecules, 2011, v. 16, n. 5, p. 4278, doi. 10.3390/molecules16054278

By:

Takami, Mihoko;
Takakusagi, Yoichi;
Kuramochi, Kouji;
Tsukuda, Senko;
Aoki, Satoko;
Morohashi, Kengo;
Ohta, Keisuke;
Kobayashi, Susumu;
Sakaguchi, Kengo;
Sugawara, Fumio

Publication type:

Article

Phage display technology for target determination of small-molecule therapeutics: an update.

Published in:

Expert Opinion on Drug Discovery, 2020, v. 15, n. 10, p. 1199, doi. 10.1080/17460441.2020.1790523

By:

Takakusagi, Yoichi;
Takakusagi, Kaori;
Sakaguchi, Kengo;
Sugawara, Fumio

Publication type:

Article

Direct Monitoring of γ-Glutamyl Transpeptidase Activity In Vivo Using a Hyperpolarized 13C-Labeled Molecular Probe.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 36, p. 10626, doi. 10.1002/anie.201603731

By:

Nishihara, Tatsuya;
Yoshihara, Hikari A. I.;
Nonaka, Hiroshi;
Takakusagi, Yoichi;
Hyodo, Fuminori;
Ichikawa, Kazuhiro;
Can, Emine;
Bastiaansen, Jessica A. M.;
Takado, Yuhei;
Comment, Arnaud;
Sando, Shinsuke

Publication type:

Article

Design of a Hyperpolarized Molecular Probe for Detection of Aminopeptidase N Activity.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 5, p. 1765, doi. 10.1002/anie.201509457

By:

Hata, Ryunosuke;
Nonaka, Hiroshi;
Takakusagi, Yoichi;
Ichikawa, Kazuhiro;
Sando, Shinsuke

Publication type:

Article

Design strategy for serine hydroxymethyltransferase probes based on retro-aldol-type reaction.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-08833-7

By:

Nonaka, Hiroshi;
Nakanishi, Yuki;
Kuno, Satoshi;
Ota, Tomoki;
Mochidome, Kentaro;
Saito, Yutaro;
Sugihara, Fuminori;
Takakusagi, Yoichi;
Aoki, Ichio;
Nagatoishi, Satoru;
Tsumoto, Kouhei;
Sando, Shinsuke

Publication type:

Article

Direct Monitoring of γ-Glutamyl Transpeptidase Activity In Vivo Using a Hyperpolarized 13C-Labeled Molecular Probe.

Published in:

Angewandte Chemie, 2016, v. 128, n. 36, p. 10784, doi. 10.1002/ange.201603731

By:

Nishihara, Tatsuya;
Yoshihara, Hikari A. I.;
Nonaka, Hiroshi;
Takakusagi, Yoichi;
Hyodo, Fuminori;
Ichikawa, Kazuhiro;
Can, Emine;
Bastiaansen, Jessica A. M.;
Takado, Yuhei;
Comment, Arnaud;
Sando, Shinsuke

Publication type:

Article

Design of a Hyperpolarized Molecular Probe for Detection of Aminopeptidase N Activity.

Published in:

Angewandte Chemie, 2016, v. 128, n. 5, p. 1797, doi. 10.1002/ange.201509457

By:

Hata, Ryunosuke;
Nonaka, Hiroshi;
Takakusagi, Yoichi;
Ichikawa, Kazuhiro;
Sando, Shinsuke

Publication type:

Article

Mapping a Disordered Portion of the Brz2001-Binding Site on a Plant Monooxygenase, DWARF4, Using a Quartz-Crystal Microbalance Biosensor-Based T7 Phage Display.

Published in:

Assay & Drug Development Technologies, 2013, v. 11, n. 3, p. 206, doi. 10.1089/adt.2012.478

By:

Takakusagi, Yoichi;
Manita, Daisuke;
Kusayanagi, Tomoe;
Izaguirre-Carbonell, Jesus;
Takakusagi, Kaori;
Kuramochi, Kouji;
Iwabata, Kazuki;
Kanai, Yoshihiro;
Sakaguchi, Kengo;
Sugawara, Fumio

Publication type:

Article

Entwicklung molekularer Sonden für die hyperpolarisierte NMR‐Bildgebung im biologischen Bereich.

Published in:

Angewandte Chemie, 2021, v. 133, n. 27, p. 14904, doi. 10.1002/ange.201915718

By:

Kondo, Yohei;
Nonaka, Hiroshi;
Takakusagi, Yoichi;
Sando, Shinsuke

Publication type:

Article

Awake brain MRSI reveals anesthetic sensitivity and regional aging effects on [13C]bicarbonate metabolism in mice.

Published in:

Frontiers in Neuroimaging, 2025, p. 1, doi. 10.3389/fnimg.2025.1506126

By:

Ono, Maiko;
Kono, Rena;
Hirata, Kosei;
Saito, Keita;
Nakao, Motonao;
Takakusagi, Yoichi;
Araki, Rikita;
Sumiyoshi, Akira;
Takado, Yuhei

Publication type:

Article

EPR and Related Magnetic Resonance Imaging Techniques in Cancer Research.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 1, p. 69, doi. 10.3390/metabo13010069

By:

Takakusagi, Yoichi;
Kobayashi, Ryoma;
Saito, Keita;
Kishimoto, Shun;
Krishna, Murali C.;
Murugesan, Ramachandran;
Matsumoto, Ken-ichiro

Publication type:

Article

Design of a 15N Molecular Unit to Achieve Long Retention of Hyperpolarized Spin State.

Published in:

Scientific Reports, 2017, p. 40104, doi. 10.1038/srep40104

By:

Nonaka, Hiroshi;
Hirano, Masashi;
Imakura, Yuki;
Takakusagi, Yoichi;
Ichikawa, Kazuhiro;
Sando, Shinsuke

Publication type:

Article

Pyruvate Induces Transient Tumor Hypoxia by Enhancing Mitochondrial Oxygen Consumption and Potentiates the Anti-Tumor Effect of a Hypoxia-Activated Prodrug TH-302.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0107995

By:

Takakusagi, Yoichi;
Matsumoto, Shingo;
Saito, Keita;
Matsuo, Masayuki;
Kishimoto, Shun;
Wojtkowiak, Jonathan W.;
DeGraff, William;
Kesarwala, Aparna H.;
Choudhuri, Rajani;
Devasahayam, Nallathamby;
Subramanian, Sankaran;
Munasinghe, Jeeva P.;
Gillies, Robert J.;
Mitchell, James B.;
Hart, Charles P.;
Krishna, Murali C.

Publication type:

Article

Identification and Characterization of the Direct Interaction between Methotrexate (MTX) and High-Mobility Group Box 1 (HMGB1) Protein

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063073

By:

Kuroiwa, Yuki;
Takakusagi, Yoichi;
Kusayanagi, Tomoe;
Kuramochi, Kouji;
Imai, Takahiko;
Hirayama, Tomoko;
Ito, Ichiaki;
Yoshida, Michiteru;
Sakaguchi, Kengo;
Sugawara, Fumio

Publication type:

Article

Heterogeneous Nucleation of Protein Crystals on Fluorinated Layered Silicate.

Published in:

PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0022582

By:

Ino, Keita;
Udagawa, Itsumi;
Iwabata, Kazuki;
Takakusagi, Yoichi;
Kubota, Munehiro;
Kurosaka, Keiichi;
Arai, Kazuhito;
Seki, Yasutaka;
Nogawa, Masaya;
Tsunoda, Tatsuo;
Mizukami, Fujio;
Taguchi, Hayao;
Sakaguchi, Kengo

Publication type:

Article

Rational Design of [13C,D14]<italic>Tert</italic>‐butylbenzene as a Scaffold Structure for Designing Long‐lived Hyperpolarized 13C Probes.

Published in:

Chemistry - An Asian Journal, 2018, v. 13, n. 3, p. 280, doi. 10.1002/asia.201701652

By:

Imakura, Yuki;
Nonaka, Hiroshi;
Takakusagi, Yoichi;
Ichikawa, Kazuhiro;
Maptue, Nesmine R.;
Funk, Alexander M.;
Khemtong, Chalermchai;
Sando, Shinsuke

Publication type:

Article

A Strategy to Design Hyperpolarized 13C Magnetic Resonance Probes Using [1-13C]α-Amino Acid as a Scaffold Structure.

Published in:

Chemistry - An Asian Journal, 2017, v. 12, n. 9, p. 949, doi. 10.1002/asia.201700098

By:

Nishihara, Tatsuya;
Kameyama, Yutaka;
Nonaka, Hiroshi;
Takakusagi, Yoichi;
Hyodo, Fuminori;
Ichikawa, Kazuhiro;
Sando, Shinsuke

Publication type:

Article

Continuous monitoring of postirradiation reoxygenation and cycling hypoxia using electron paramagnetic resonance imaging.

Published in:

NMR in Biomedicine, 2022, v. 35, n. 10, p. 1, doi. 10.1002/nbm.4783

By:

Kawai, Tatsuya;
Matsuo, Masayuki;
Takakusagi, Yoichi;
Saito, Keita;
Hyodo, Fuminori;
Devasahayam, Nallathamby;
Matsumoto, Shingo;
Kishimoto, Shun;
Yasui, Hironobu;
Yamamoto, Kazutoshi;
Krishna, Murali C.

Publication type:

Article

Editorial: Targeting and monitoring cancer metabolism: novel theranostics for colorectal cancer.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1575563

By:

Oshima, Nobu;
Aisu, Yuki;
Masuo, Akihiko;
Takakusagi, Yoichi;
Kawai, Tatsuya

Publication type:

Article

Lariatins, Novel Anti-mycobacterial Peptides with a Lasso Structure, Produced by Rhodococcus jostii K01-B0171.

Published in:

Journal of Antibiotics, 2007, v. 60, n. 6, p. 357, doi. 10.1038/ja.2007.48

By:

Iwatsuki, Masato;
Uchida, Ryuji;
Takakusagi, Yoichi;
Matsumoto, Atsuko;
Jiang, Cheng-Lin;
Takahashi, Yoko;
Arai, Masayoshi;
Kobayashi, Susumu;
Matsumoto, Makoto;
Inokoshi, Junji;
Tomoda, Hiroshi;
Ōmura, Satoshi

Publication type:

Article

Works by Takakusagi, Yoichi

Activation of oxidoreductases by the formation of enzyme assembly.

Design of Nuclear Magnetic Resonance Molecular Probes for Hyperpolarized Bioimaging.

A Screening of a Library of T7 Phage-Displayed Peptide Identifies E2F-4 as an Etoposide-Binding Protein.

Phage display technology for target determination of small-molecule therapeutics: an update.

Direct Monitoring of γ-Glutamyl Transpeptidase Activity In Vivo Using a Hyperpolarized <sup>13</sup>C-Labeled Molecular Probe.

Design of a Hyperpolarized Molecular Probe for Detection of Aminopeptidase N Activity.

Design strategy for serine hydroxymethyltransferase probes based on retro-aldol-type reaction.

Direct Monitoring of γ-Glutamyl Transpeptidase Activity In Vivo Using a Hyperpolarized <sup>13</sup>C-Labeled Molecular Probe.

Design of a Hyperpolarized Molecular Probe for Detection of Aminopeptidase N Activity.

Mapping a Disordered Portion of the Brz2001-Binding Site on a Plant Monooxygenase, DWARF4, Using a Quartz-Crystal Microbalance Biosensor-Based T7 Phage Display.

Entwicklung molekularer Sonden für die hyperpolarisierte NMR‐Bildgebung im biologischen Bereich.

Awake brain MRSI reveals anesthetic sensitivity and regional aging effects on [<sup>13</sup>C]bicarbonate metabolism in mice.

EPR and Related Magnetic Resonance Imaging Techniques in Cancer Research.

Design of a <sup>15</sup>N Molecular Unit to Achieve Long Retention of Hyperpolarized Spin State.

Pyruvate Induces Transient Tumor Hypoxia by Enhancing Mitochondrial Oxygen Consumption and Potentiates the Anti-Tumor Effect of a Hypoxia-Activated Prodrug TH-302.

Identification and Characterization of the Direct Interaction between Methotrexate (MTX) and High-Mobility Group Box 1 (HMGB1) Protein

Heterogeneous Nucleation of Protein Crystals on Fluorinated Layered Silicate.

Rational Design of [<sup>13</sup>C,D<sub>14</sub>]<italic>Tert</italic>‐butylbenzene as a Scaffold Structure for Designing Long‐lived Hyperpolarized <sup>13</sup>C Probes.

A Strategy to Design Hyperpolarized <sup>13</sup>C Magnetic Resonance Probes Using [1-<sup>13</sup>C]α-Amino Acid as a Scaffold Structure.

Continuous monitoring of postirradiation reoxygenation and cycling hypoxia using electron paramagnetic resonance imaging.

Editorial: Targeting and monitoring cancer metabolism: novel theranostics for colorectal cancer.

Lariatins, Novel Anti-mycobacterial Peptides with a Lasso Structure, Produced by Rhodococcus jostii K01-B0171.