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Autophagy Inhibits the Accumulation of Advanced Glycation End Products by Promoting Lysosomal Biogenesis and Function in the Kidney Proximal Tubules.
Published in:
2017
By:
- Atsushi Takahashi;
- Yoshitsugu Takabatake;
- Tomonori Kimura;
- Ikuko Maejima;
- Tomoko Namba;
- Takeshi Yamamoto;
- Jun Matsuda;
- Satoshi Minami;
- Jun-ya Kaimori;
- Isao Matsui;
- Taiji Matsusaka;
- Fumio Niimura;
- Tamotsu Yoshimori;
- Yoshitaka Isaka;
- Takahashi, Atsushi;
- Takabatake, Yoshitsugu;
- Kimura, Tomonori;
- Maejima, Ikuko;
- Namba, Tomoko;
- Yamamoto, Takeshi
Publication type:
journal article
Urinary mulberry bodies as a potential biomarker for early diagnosis and efficacy assessment of enzyme replacement therapy in Fabry nephropathy.
Published in:
Nephrology Dialysis Transplantation, 2022, v. 37, n. 1, p. 53, doi. 10.1093/ndt/gfaa298
By:
- Yonishi, Hiroaki;
- Namba-Hamano, Tomoko;
- Hamano, Takayuki;
- Hotta, Masaki;
- Nakamura, Jun;
- Sakai, Shinsuke;
- Minami, Satoshi;
- Yamamoto, Takeshi;
- Takahashi, Atsushi;
- Kobayashi, Wataru;
- Maeda, Ikuhiro;
- Hidaka, Yoh;
- Takabatake, Yoshitsugu;
- Sakai, Norio;
- Isaka, Yoshitaka
Publication type:
Article
Proteinuria-associated renal magnesium wasting leads to hypomagnesemia: a common electrolyte abnormality in chronic kidney disease.
Published in:
Nephrology Dialysis Transplantation, 2019, v. 34, n. 7, p. 1154, doi. 10.1093/ndt/gfy119
By:
- Oka, Tatsufumi;
- Hamano, Takayuki;
- Sakaguchi, Yusuke;
- Yamaguchi, Satoshi;
- Kubota, Keiichi;
- Senda, Masamitsu;
- Yonemoto, Sayoko;
- Shimada, Karin;
- Matsumoto, Ayumi;
- Hashimoto, Nobuhiro;
- Mori, Daisuke;
- Monden, Chikako;
- Takahashi, Atsushi;
- Obi, Yoshitsugu;
- Yamamoto, Ryohei;
- Takabatake, Yoshitsugu;
- Kaimori, Jun-Ya;
- Moriyama, Toshiki;
- Horio, Masaru;
- Matsui, Isao
Publication type:
Article
Excess 25-hydroxyvitamin D3 exacerbates tubulointerstitial injury in mice by modulating macrophage phenotype.
Published in:
2015
By:
- Kusunoki, Yasuo;
- Matsui, Isao;
- Hamano, Takayuki;
- Shimomura, Akihiro;
- Mori, Daisuke;
- Yonemoto, Sayoko;
- Takabatake, Yoshitsugu;
- Tsubakihara, Yoshiharu;
- St-Arnaud, René;
- Isaka, Yoshitaka;
- Rakugi, Hiromi;
- St-Arnaud, René
Publication type:
journal article
Suppression of autophagic activity by Rubicon is a signature of aging.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-08729-6
By:
- Nakamura, Shuhei;
- Oba, Masaki;
- Suzuki, Mari;
- Takahashi, Atsushi;
- Yamamuro, Tadashi;
- Fujiwara, Mari;
- Ikenaka, Kensuke;
- Minami, Satoshi;
- Tabata, Namine;
- Yamamoto, Kenichi;
- Kubo, Sayaka;
- Tokumura, Ayaka;
- Akamatsu, Kanako;
- Miyazaki, Yumi;
- Kawabata, Tsuyoshi;
- Hamasaki, Maho;
- Fukui, Koji;
- Sango, Kazunori;
- Watanabe, Yoshihisa;
- Takabatake, Yoshitsugu
Publication type:
Article
Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury.
Published in:
EMBO Journal, 2013, v. 32, n. 17, p. 2336, doi. 10.1038/emboj.2013.171
By:
- Maejima, Ikuko;
- Takahashi, Atsushi;
- Omori, Hiroko;
- Kimura, Tomonori;
- Takabatake, Yoshitsugu;
- Saitoh, Tatsuya;
- Yamamoto, Akitsugu;
- Hamasaki, Maho;
- Noda, Takeshi;
- Isaka, Yoshitaka;
- Yoshimori, Tamotsu
Publication type:
Article
"Pseudo-empty pelvis" in a pre-dialysis patient.
Published in:
Peritoneal Dialysis International, 2020, v. 40, n. 4, p. 431, doi. 10.1177/0896860819899579
By:
- Ayumi Matsumoto;
- Isao Matsui;
- Yusuke Sakaguchi;
- Harumi Kitamura;
- Maki Shinzawa;
- Chikako Monden;
- Atsushi Takahashi;
- Yoshitsugu Takabatake;
- Yoshitaka Isaka
Publication type:
Article
TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis.
Published in:
Nature Immunology, 2009, v. 10, n. 9, p. 965, doi. 10.1038/ni.1771
By:
- Kawagoe, Tatsukata;
- Takeuchi, Osamu;
- Takabatake, Yoshitsugu;
- Kato, Hiroki;
- Isaka, Yoshitaka;
- Tsujimura, Tohru;
- Akira, Shizuo
Publication type:
Article
Single cell RNA sequencing uncovers cellular developmental sequences and novel potential intercellular communications in embryonic kidney.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-80154-y
By:
- Matsui, Isao;
- Matsumoto, Ayumi;
- Inoue, Kazunori;
- Katsuma, Yusuke;
- Yasuda, Seiichi;
- Shimada, Karin;
- Sakaguchi, Yusuke;
- Mizui, Masayuki;
- Kaimori, Jun-ya;
- Takabatake, Yoshitsugu;
- Isaka, Yoshitaka
Publication type:
Article
Dietary casein, egg albumin, and branched-chain amino acids attenuate phosphate-induced renal tubulointerstitial injury in rats.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-76228-6
By:
- Shimada, Karin;
- Matsui, Isao;
- Inoue, Kazunori;
- Matsumoto, Ayumi;
- Yasuda, Seiichi;
- Katsuma, Yusuke;
- Sakaguchi, Yusuke;
- Tanaka, Minoru;
- Sugimoto, Ken;
- Kaimori, Jun-ya;
- Takabatake, Yoshitsugu;
- Isaka, Yoshitaka
Publication type:
Article
Association between Density of Coronary Artery Calcification and Serum Magnesium Levels among Patients with Chronic Kidney Disease.
Published in:
PLoS ONE, 2016, v. 11, n. 9, p. 1, doi. 10.1371/journal.pone.0163673
By:
- Sakaguchi, Yusuke;
- Hamano, Takayuki;
- Nakano, Chikako;
- Obi, Yoshitsugu;
- Matsui, Isao;
- Kusunoki, Yasuo;
- Mori, Daisuke;
- Oka, Tatsufumi;
- Hashimoto, Nobuhiro;
- Takabatake, Yoshitsugu;
- Takahashi, Atsushi;
- Kaimori, Jun-Ya;
- Moriyama, Toshiki;
- Yamamoto, Ryohei;
- Horio, Masaru;
- Sugimoto, Ken;
- Yamamoto, Koichi;
- Rakugi, Hiromi;
- Isaka, Yoshitaka
Publication type:
Article
Azilsartan Improves Salt Sensitivity by Modulating the Proximal Tubular Na<sup>+</sup>-H<sup>+</sup> Exchanger-3 in Mice.
Published in:
PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0147786
By:
- Hatanaka, Masaki;
- Kaimori, Jun-Ya;
- Yamamoto, Satoko;
- Matsui, Isao;
- Hamano, Takayuki;
- Takabatake, Yoshitsugu;
- Ecelbarger, Carolyn M.;
- Takahara, Shiro;
- Isaka, Yoshitaka;
- Rakugi, Hiromi
Publication type:
Article
Maxacalcitol (22-Oxacalcitriol (OCT)) Retards Progression of Left Ventricular Hypertrophy with Renal Dysfunction Through Inhibition of Calcineurin-NFAT Activity.
Published in:
Cardiovascular Drugs & Therapy, 2021, v. 35, n. 2, p. 381, doi. 10.1007/s10557-020-07111-9
By:
- Inoue, Kazunori;
- Matsui, Isao;
- Hamano, Takayuki;
- Okuda, Keiji;
- Tsukamoto, Yasumasa;
- Matsumoto, Ayumi;
- Shimada, Karin;
- Yasuda, Seiichi;
- Katsuma, Yusuke;
- Takabatake, Yoshitsugu;
- Tanaka, Masaru;
- Tanaka, Noriko;
- Mano, Toshiaki;
- Minamino, Tetsuo;
- Sakata, Yasushi;
- Isaka, Yoshitaka
Publication type:
Article
A Superagonistic Monoclonal Antibody for CD28 Ameliorates Crescentic Glomerulonephritis in Wistar-Kyoto Rats.
Published in:
Molecular Medicine, 2011, v. 17, n. 7/8, p. 686, doi. 10.2119/molmed.2010.00229
By:
- Takabatake, Yoshitsugu;
- Li, Xiao-Kang;
- Mizui, Masayuki;
- Miyasato, Kenro;
- Matsui, Isao;
- Kawada, Noritaka;
- Imai, Enyu;
- Hünig, Thomas;
- Takahara, Shiro;
- Wada, Takashi;
- Furuichi57,8, Kengo;
- Rakugi, Hiromi;
- Isaka, Yoshitaka
Publication type:
Article
Establishment and clinical application of SARS-CoV-2 catch column.
Published in:
Clinical & Experimental Nephrology, 2023, v. 27, n. 3, p. 279, doi. 10.1007/s10157-022-02296-9
By:
- Isaka, Yoshitaka;
- Yoshiya, Taku;
- Ono, Chikako;
- Uchiyama, Akinori;
- Hirata, Haruhiko;
- Hamaguchi, Shigeto;
- Kutsuna, Satoshi;
- Takabatake, Yoshitsugu;
- Saita, Ryotaro;
- Yamada, Tomomi;
- Takahashi, Atsushi;
- Yamato, Masaya;
- Nohara, Yukie;
- Tsuda, Shugo;
- Anzai, Itsuki;
- Kimura, Tomonori;
- Takeda, Yoshito;
- Tomono, Kazunori;
- Matsuura, Yoshiharu
Publication type:
Article
Histochemical and immunoelectron microscopic analysis of ganglioside GM3 in human kidney.
Published in:
Clinical & Experimental Nephrology, 2015, v. 19, n. 3, p. 403, doi. 10.1007/s10157-014-1003-0
By:
- Kaneko, Tetsuya;
- Tsubakihara, Yoshiharu;
- Fushimi, Hiroaki;
- Yamaguchi, Seiji;
- Takabatake, Yoshitsugu;
- Rakugi, Hiromi;
- Kawakami, Hayato;
- Isaka, Yoshitaka
Publication type:
Article
Use of xanthine oxidase inhibitor febuxostat inhibits renal interstitial inflammation and fibrosis in unilateral ureteral obstructive nephropathy.
Published in:
Clinical & Experimental Nephrology, 2012, v. 16, n. 4, p. 549, doi. 10.1007/s10157-012-0609-3
By:
- Omori, Hiroki;
- Kawada, Noritaka;
- Inoue, Kazunori;
- Ueda, Yoshiyasu;
- Yamamoto, Ryohei;
- Matsui, Isao;
- Kaimori, Jyunya;
- Takabatake, Yoshitsugu;
- Moriyama, Toshiki;
- Isaka, Yoshitaka;
- Rakugi, Hiromi
Publication type:
Article
Towards developing new strategies to reduce the adverse side-effects of nonsteroidal anti-inflammatory drugs.
Published in:
Clinical & Experimental Nephrology, 2012, v. 16, n. 1, p. 25, doi. 10.1007/s10157-011-0492-3
By:
- Kawada, Noritaka;
- Moriyama, Toshiki;
- Kitamura, Harumi;
- Yamamoto, Ryohei;
- Furumatsu, Yoshiyuki;
- Matsui, Isao;
- Takabatake, Yoshitsugu;
- Nagasawa, Yasuyuki;
- Imai, Enyu;
- Wilcox, Christopher;
- Rakugi, Hiromi;
- Isaka, Yoshitaka
Publication type:
Article
CD28 superagonist-induced regulatory T cell expansion ameliorates mesangioproliferative glomerulonephritis in rats.
Published in:
Clinical & Experimental Nephrology, 2011, v. 15, n. 1, p. 50, doi. 10.1007/s10157-010-0370-4
By:
- Miyasato, Kenro;
- Takabatake, Yoshitsugu;
- Kaimori, Junya;
- Kimura, Tomonori;
- Kitamura, Harumi;
- Kawachi, Hiroshi;
- Li, Xiao-Kang;
- Hünig, Thomas;
- Takahara, Shiro;
- Rakugi, Hiromi;
- Isaka, Yoshitaka
Publication type:
Article
Negative effects of anemia on quality of life and its improvement by complete correction of anemia by administration of recombinant human erythropoietin in posttransplant patients.
Published in:
Clinical & Experimental Nephrology, 2009, v. 13, n. 4, p. 355, doi. 10.1007/s10157-009-0170-x
By:
- Kawada, Noritaka;
- Moriyama, Toshiki;
- Ichimaru, Naotsugu;
- Imamura, Ryoichi;
- Matsui, Isao;
- Takabatake, Yoshitsugu;
- Nagasawa, Yasuyuki;
- Isaka, Yoshitaka;
- Kojima, Yasuyuki;
- Kokado, Yukito;
- Rakugi, Hiromi;
- Imai, Enyu;
- Takahara, Shiro
Publication type:
Article
Hyperuricemia-induced inflammasome and kidney diseases.
Published in:
Nephrology Dialysis Transplantation, 2016, v. 31, n. 6, p. 890, doi. 10.1093/ndt/gfv024
By:
- Yoshitaka Isaka;
- Yoshitsugu Takabatake;
- Atsushi Takahashi;
- Tatsuya Saitoh;
- Tamotsu Yoshimori
Publication type:
Article
Autophagy and the kidney: health and disease.
Published in:
Nephrology Dialysis Transplantation, 2014, v. 29, n. 9, p. 1639, doi. 10.1093/ndt/gft535
By:
- Takabatake, Yoshitsugu;
- Kimura, Tomonori;
- Takahashi, Atsushi;
- Isaka, Yoshitaka
Publication type:
Article
Specialist care and improved long-term survival of dialysis patients.
Published in:
Nephrology Dialysis Transplantation, 2010, v. 25, n. 6, p. 1930, doi. 10.1093/ndt/gfp738
By:
- Furumatsu, Yoshiyuki;
- Nagasawa, Yasuyuki;
- Yamamoto, Ryohei;
- Iio, Kenichiro;
- Iwatani, Hirotsugu;
- Matsui, Isao;
- Takabatake, Yoshitsugu;
- Kawada, Noritaka;
- Shoji, Tatsuya;
- Imai, Enyu;
- Isaka, Yoshitaka;
- Rakugi, Hiromi
Publication type:
Article
Active vitamin D and its analogue, 22-oxacalcitriol, ameliorate puromycin aminonucleoside-induced nephrosis in rats.
Published in:
Nephrology Dialysis Transplantation, 2009, v. 24, n. 8, p. 2354, doi. 10.1093/ndt/gfp117
By:
- Matsui, Isao;
- Hamano, Takayuki;
- Tomida, Kodo;
- Inoue, Kazunori;
- Takabatake, Yoshitsugu;
- Nagasawa, Yasuyuki;
- Kawada, Noritaka;
- Ito, Takahito;
- Kawachi, Hiroshi;
- Rakugi, Hiromi;
- Imai, Enyu;
- Isaka, Yoshitaka
Publication type:
Article
Nonerythropoietic derivative of erythropoietin protects against tubulointerstitial injury in a unilateral ureteral obstruction model.
Published in:
Nephrology Dialysis Transplantation, 2008, v. 23, n. 5, p. 1521, doi. 10.1093/ndt/gfm842
By:
- Harumi Kitamura;
- Yoshitaka Isaka;
- Yoshitsugu Takabatake;
- Ryoichi Imamura;
- Chigure Suzuki;
- Shiro Takahara;
- Enyu Imai
Publication type:
Article
Targeting of interstitial cells using a simple gene-transfer strategy.
Published in:
Nephrology Dialysis Transplantation, 2006, v. 21, n. 10, p. 2745, doi. 10.1093/ndt/gfl327
By:
- Naohiko Fujii;
- Yoshitaka Isaka;
- Yoshitsugu Takabatake;
- Masayuki Mizui;
- Chigure Suzuki;
- Shiro Takahara;
- Takahito Ito;
- Enyu Imai
Publication type:
Article
Renal artery injection for delivery of biological materials to the glomerulus (Methods in Renal Research Paper).
Published in:
Nephrology, 2008, v. 13, n. 1, p. 23, doi. 10.1111/j.1440-1797.2007.00907.x
By:
- TAKABATAKE, YOSHITSUGU;
- ISAKA, YOSHITAKA;
- IMAI, ENYU
Publication type:
Article
Fully phosphorylated fetuin-A forms a mineral complex in the serum of rats with adenine-induced renal failure.
Published in:
Kidney International, 2009, v. 75, n. 9, p. 915, doi. 10.1038/ki.2008.700
By:
- Matsui, Isao;
- Hamano, Takayuki;
- Mikami, Satoshi;
- Fujii, Naohiko;
- Takabatake, Yoshitsugu;
- Nagasawa, Yasuyuki;
- Kawada, Noritaka;
- Ito, Takahito;
- Rakugi, Hiromi;
- Imai, Enyu;
- Isaka, Yoshitaka
Publication type:
Article
DNAzyme for TGF-β suppressed extracellular matrix accumulation in experimental glomerulonephritis.
Published in:
Kidney International, 2004, v. 66, n. 2, p. 586, doi. 10.1111/j.1523-1755.2004.00777.x
By:
- Isaka, Yoshitaka;
- Nakamura, Hiroyuki;
- Mizui, Masayuki;
- Takabatake, Yoshitsugu;
- H orio, Masaru;
- Kawachi, Hiroshi;
- Shimizu, Fujio;
- Imai, Enyu;
- Hori, Masatsugu
Publication type:
Article
RENAL PARTICIPANTS Gene therapy in renal diseases.
Published in:
Kidney International, 2004, v. 65, n. 5, p. 1551, doi. 10.1111/j.1523-1755.2004.05409.x
By:
- Imai, Enyu;
- Takabatake, Yoshitsugu;
- Mizui, Masayuki;
- Isaka, Yoshitaka
Publication type:
Article

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