Works by Tainer, John A.

Results: 134

Characterizing flexible and intrinsically unstructured biological macromolecules by SAS using the Porod-Debye law.

Published in:

Biopolymers, 2011, v. 95, n. 8, p. 559, doi. 10.1002/bip.21638

By:

Rambo, Robert P.;
Tainer, John A.

Publication type:

Article

Cracking tyrosine phosphatases.

Published in:

Nature, 1994, v. 370, n. 6490, p. 506, doi. 10.1038/370506a0

By:

Tainer, John;
Russell, Paul

Publication type:

Article

The pilus and porin of Neisseria gonorrhoeae cooperatively induce Ca2+ transients in infected epithelial cells.

Published in:

Cellular Microbiology, 2005, v. 7, n. 12, p. 1736, doi. 10.1111/j.1462-5822.2005.00586.x

By:

Ayala, Patricia;
Wilbur, J. Scott;
Wetzler, Lee M.;
Tainer, John A.;
Snyder, Aurelie;
So, Magdalene

Publication type:

Article

The pilus-induced Ca[sup2+] flux triggers lysosome exocytosis and increases the amount of Lamp1 accessible to Neisseria IgA1 protease.

Published in:

Cellular Microbiology, 2001, v. 3, n. 4, p. 265, doi. 10.1046/j.1462-5822.2001.00112.x

By:

Ayala, B. Patricia;
Vasquez, Brandi;
Clary, Susan;
Tainer, John A.;
Rodland, Karin;
So, Magdalene

Publication type:

Article

The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase.

Published in:

Nucleic Acids Research, 2007, v. 35, n. 5, p. 1624, doi. 10.1093/nar/gkm006

By:

Vijayakumar, Sangeetha;
Chapados, Brian R.;
Schmidt, Kristina H.;
Kolodner, Richard D.;
Tainer, John A.;
Tomkinson, Alan E.

Publication type:

Article

Proliferating cell nuclear antigen loaded onto double-stranded DNA: dynamics, minor groove interactions and functional implications.

Published in:

Nucleic Acids Research, 2006, v. 34, n. 20, p. 6023, doi. 10.1093/nar/gkl744

By:

Ivanov, Ivaylo;
Chapados, Brian R.;
McCammon, J. Andrew;
Tainer, John A.

Publication type:

Article

Synthesis and characterization of oligonucleotides containing 2′-fluorinated thymidine glycol as inhibitors of the endonuclease III reaction.

Published in:

Nucleic Acids Research, 2006, v. 34, n. 5, p. 1540, doi. 10.1093/nar/gkl061

By:

Doi, Yusuke;
Katafuchi, Atsushi;
Fujiwara, Yoshie;
Hitomi, Kenichi;
Tainer, John A.;
Ide, Hiroshi;
Iwai, Shigenori

Publication type:

Article

Structural and functional analysis of Mre11‐3.

Published in:

Nucleic Acids Research, 2004, v. 32, n. 6, p. 1886, doi. 10.1093/nar/gkh343

By:

Arthur, L. Matthew;
Gustausson, Karin;
Hopfner, Karl‐Peter;
Carson, Christian T.;
Stracker, Travis H.;
Karcher, Annette;
Felton, Diana;
Weitzman, Matthew D.;
Tainer, John;
Carney, James P.

Publication type:

Article

MDB: the Metalloprotein Database and Browser at The Scripps Research Institute.

Published in:

Nucleic Acids Research, 2002, v. 30, n. 1, p. 379, doi. 10.1093/nar/30.1.379

By:

Castagnetto, Jesus M.;
Hennessy, Sean W.;
Roberts, Victoria A.;
Getzoff, Elizabeth D.;
Tainer, John A.;
Pique, Michael E.

Publication type:

Article

Author Correction: Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology.

Published in:

2024

By:

Filandr, Frantisek;
Sarpe, Vladimir;
Raval, Shaunak;
Crowder, D. Alex;
Khan, Morgan F.;
Douglas, Pauline;
Coales, Stephen;
Viner, Rosa;
Syed, Aleem;
Tainer, John A.;
Lees-Miller, Susan P.;
Schriemer, David C.

Publication type:

Correction Notice

Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46610-3

By:

Filandr, Frantisek;
Sarpe, Vladimir;
Raval, Shaunak;
Crowder, D. Alex;
Khan, Morgan F.;
Douglas, Pauline;
Coales, Stephen;
Viner, Rosa;
Syed, Aleem;
Tainer, John A.;
Lees-Miller, Susan P.;
Schriemer, David C.

Publication type:

Article

Dynamic conformational switching underlies TFIIH function in transcription and DNA repair and impacts genetic diseases.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38416-6

By:

Yu, Jina;
Yan, Chunli;
Dodd, Thomas;
Tsai, Chi-Lin;
Tainer, John A.;
Tsutakawa, Susan E.;
Ivanov, Ivaylo

Publication type:

Article

All Stressed Out Without ATM Kinase.

Published in:

Science Signaling, 2011, v. 4, n. 167, p. 1, doi. 10.1126/scisignal.2001961

By:

Perry, J. Jefferson P.;
Tainer, John A.

Publication type:

Article

Implementation and performance of SIBYLS: a dual endstation small-angle X-ray scattering and macromolecular crystallography beamline at the Advanced Light Source.

Published in:

Journal of Applied Crystallography, 2013, v. 46, n. 1, p. 1, doi. 10.1107/S0021889812048698

By:

Classen, Scott;
Hura, Greg L.;
Holton, James M.;
Rambo, Robert P.;
Rodic, Ivan;
McGuire, Patrick J.;
Dyer, Kevin;
Hammel, Michal;
Meigs, George;
Frankel, Kenneth A.;
Tainer, John A.

Publication type:

Article

X‐ray scattering reveals disordered linkers and dynamic interfaces in complexes and mechanisms for DNA double‐strand break repair impacting cell and cancer biology.

Published in:

Protein Science: A Publication of the Protein Society, 2021, v. 30, n. 9, p. 1735, doi. 10.1002/pro.4133

By:

Hammel, Michal;
Tainer, John A.

Publication type:

Article

ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.

Published in:

EMBO Journal, 2014, v. 33, n. 5, p. 482, doi. 10.1002/embj.201386100

By:

Deshpande, Rajashree A;
Williams, Gareth J;
Limbo, Oliver;
Williams, R Scott;
Kuhnlein, Jeff;
Lee, Ji‐Hoon;
Classen, Scott;
Guenther, Grant;
Russell, Paul;
Tainer, John A;
Paull, Tanya T

Publication type:

Article

P53 conformational switching for selectivity may reveal a general solution for specific DNA binding.

Published in:

EMBO Journal, 2011, v. 30, n. 11, p. 2099, doi. 10.1038/emboj.2011.133

By:

Tubbs, Julie L;
Tainer, John A

Publication type:

Article

γH2A binds Brc1 to maintain genome integrity during S-phase.

Published in:

EMBO Journal, 2010, v. 29, n. 6, p. 1136, doi. 10.1038/emboj.2009.413

By:

Williams, Jessica S.;
Williams, R. Scott;
Dovey, Claire L.;
Guenther, Grant;
Tainer, John A.;
Russell, Paul

Publication type:

Article

SUMO-targeted ubiquitin ligases in genome stability.

Published in:

EMBO Journal, 2007, v. 26, n. 18, p. 4089, doi. 10.1038/sj.emboj.7601838

By:

Prudden, John;
Pebernard, Stephanie;
Raffa, Grazia;
Slavin, Daniela A.;
Perry, J. Jefferson P.;
Tainer, John A.;
McGowan, Clare H.;
Boddy, Michael N.

Publication type:

Article

Hexameric structures of the archaeal secretion ATPase GspE and implications for a universal secretion mechanism.

Published in:

EMBO Journal, 2007, v. 26, n. 3, p. 878, doi. 10.1038/sj.emboj.7601544

By:

Yamagata, Atsushi;
Tainer, John A

Publication type:

Article

Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage.

Published in:

EMBO Journal, 2006, v. 25, n. 14, p. 3389, doi. 10.1038/sj.emboj.7601219

By:

Sundheim, Ottar;
Vågbø, Cathrine B.;
Bjørås, Magnar;
Sousa, Mirta M. L.;
Talstad, Vivi;
Aas, Per A.;
Drabløs, Finn;
Krokan, Hans E.;
Tainer, John A.;
Slupphaug, Geir

Publication type:

Article

Structural basis for endothelial nitric oxide synthase binding to calmodulin.

Published in:

EMBO Journal, 2003, v. 22, n. 4, p. 766, doi. 10.1093/emboj/cdg078

By:

Aoyagi, Mika;
Arvai, Andrew S.;
Tainer, John A.;
Getzoff, Elizabeth D.

Publication type:

Article

Structural basis for endothelial nitric oxide synthase binding to calmodulin.

Published in:

2003

By:

Aoyagi, Mika;
Arvai, Andrew S.;
Tainer, John A.;
Getzoff, Elizabeth D.

Publication type:

Correction Notice

Structural basis for recognition of 5?-phosphotyrosine adducts by Tdp2.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 12, p. 1372, doi. 10.1038/nsmb.2423

By:

Shi, Ke;
Kurahashi, Kayo;
Gao, Rui;
Tsutakawa, Susan E;
Tainer, John A;
Pommier, Yves;
Aihara, Hideki

Publication type:

Article

Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 6, p. 653, doi. 10.1038/nsmb.2305

By:

Kim, In-Kwon;
Kiefer, James R;
Ho, Chris M W;
Stegeman, Roderick A;
Classen, Scott;
Tainer, John A;
Ellenberger, Tom

Publication type:

Article

ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 3, p. 364, doi. 10.1038/nsmb0312-364a

By:

Williams, Gareth J;
Williams, R Scott;
Williams, Jessica S;
Moncalian, Gabriel;
Arvai, Andrew S;
Limbo, Oliver;
Guenther, Grant;
SilDas, Soumita;
Hammel, Michal;
Russell, Paul;
Tainer, John A

Publication type:

Article

ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.

Published in:

2011

By:

Williams, Gareth J.;
Williams, R. Scott;
Williams, Jessica S.;
Moncalian, Gabriel;
Arvai, Andrew S.;
Limbo, Oliver;
Guenther, Grant;
SilDas, Soumita;
Hammel, Michal;
Russell, Paul;
Tainer, John A.

Publication type:

Correction Notice

ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 4, p. 423, doi. 10.1038/nsmb.2038

By:

Williams, Gareth J.;
Williams, R. Scott;
Williams, Jessica S.;
Moncalian, Gabriel;
Arvai, Andrew S.;
Limbo, Oliver;
Guenther, Grant;
SilDas, Soumita;
Hammel, Michal;
Russell, Paul;
Tainer, John A.

Publication type:

Article

Molecular mimicry of SUMO promotes DNA repair.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 5, p. 509, doi. 10.1038/nsmb.1582

By:

Prudden, John;
Perry, J. Jefferson P.;
Arvai, Andrew S.;
Tainer, John A.;
Boddy, Michael N.

Publication type:

Article

Structures of endonuclease V with DNA reveal initiation of deaminated adenine repair.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 2, p. 138, doi. 10.1038/nsmb.1538

By:

Dalhus, Bjørn;
Arvai, Andrew S;
Rosnes, Ida;
Olsen, Øyvind E;
Backe, Paul H;
Alseth, Ingrun;
Gao, Honghai;
Cao, Weiguo;
Tainer, John A;
Bjørås, Magnar

Publication type:

Article

DNA apurinic-apyrimidinic site binding and excision by endonuclease IV.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 5, p. 515, doi. 10.1038/nsmb.1414

By:

Garcin, Elsa D.;
Hosfield, David J.;
Desai, Sunil A.;
Haas, Brian J.;
Björas, Magnar;
Cunningham, Richard P.;
Tainer, John A.

Publication type:

Article

WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 5, p. 414, doi. 10.1038/nsmb1088

By:

Perry, J Jefferson P;
Yannone, Steven M;
Holden, Lauren G;
Hitomi, Chiharu;
Asaithamby, Aroumougame;
Han, Seungil;
Cooper, Priscilla K;
Chen, David J;
Tainer, John A

Publication type:

Article

DNA binding and nucleotide flipping by the human DNA repair protein AGT.

Published in:

Nature Structural & Molecular Biology, 2004, v. 11, n. 8, p. 714, doi. 10.1038/nsmb791

By:

Daniels, Douglas S.;
Woo, Tammy T.;
Luu, Kieu X.;
Noll, David M.;
Clarke, Neil D.;
Pegg, Anthony E.;
Tainer, John A.

Publication type:

Article

Manganese superoxide dismutase induction during measles virus infection (M. Wang and J.M. Howell contributed equally to this submission.).

Published in:

Journal of Medical Virology, 2003, v. 70, n. 3, p. 470

By:

Michael Wang;
Joseph M. Howell;
Jane E. Libbey;
John A. Tainer;
Robert S. Fujinami

Publication type:

Article

Distinct sequence features underlie microdeletions and gross deletions in the human genome.

Published in:

Human Mutation, 2022, v. 43, n. 3, p. 328, doi. 10.1002/humu.24314

By:

Qi, Mengling;
Stenson, Peter D.;
Ball, Edward V.;
Tainer, John A.;
Bacolla, Albino;
Kehrer‐Sawatzki, Hildegard;
Cooper, David N.;
Zhao, Huiying

Publication type:

Article

A goldilocks computational protocol for inhibitor discovery targeting DNA damage responses including replication-repair functions.

Published in:

Frontiers in Molecular Biosciences, 2024, p. 1, doi. 10.3389/fmolb.2024.1442267

By:

Moiani, Davide;
Tainer, John A.

Publication type:

Article

Author Correction: Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05295-1

By:

Hou-Fu Guo;
Chi-Lin Tsai;
Masahiko Terajima;
Xiaochao Tan;
Banerjee, Priyam;
Miller, Mitchell D.;
Xin Liu;
Jiang Yu;
Byemerwa, Jovita;
Alvarado, Sarah;
Kaoud, Tamer S.;
Dalby, Kevin N.;
Bota-Rabassedas, Neus;
Yulong Chen;
Mitsuo Yamauchi;
Tainer, John A.;
Phillips Jr., George N.;
Kurie, Jonathan M.

Publication type:

Article

Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-02859-z

By:

Hou-Fu Guo;
Chi-Lin Tsai;
Masahiko Terajima;
Xiaochao Tan;
Banerjee, Priyam;
Miller, Mitchell D.;
Xin Liu;
Jiang Yu;
Byemerwa, Jovita;
Alvarado, Sarah;
Kaoud, Tamer S.;
Dalby, Kevin N.;
Bota-Rabassedas, Neus;
Yulong Chen;
Mitsuo Yamauchi;
Tainer, John A.;
Phillips Jr., George N.;
Kurie, Jonathan M.

Publication type:

Article

Corrigendum: Phosphate steering by Flap Endonuclease 1 promotes 5′-flap specificity and incision to prevent genome instability.

Published in:

Nature Communications, 2017, v. 8, n. 8, p. -1, doi. 10.1038/ncomms16145

By:

Tsutakawa, Susan E.;
Thompson, Mark J.;
Arvai, Andrew S.;
Neil, Alexander J.;
Shaw, Steven J.;
Algasaier, Sana I.;
Kim, Jane C.;
Finger, L. David;
Jardine, Emma;
Gotham, Victoria J. B.;
Sarker, Altaf H.;
Her, Mai Z.;
Rashid, Fahad;
Hamdan, Samir M.;
Mirkin, Sergei M.;
Grasby, Jane A.;
Tainer, John A.

Publication type:

Article

Screening a Peptidyl Database for Potential Ligands to Proteins With Side-Chain Flexibility

Published in:

Proteins, 1998, v. 33, n. 1, p. 74

By:

Schnecke, Volker;
Swanson, Craig A.;
Getzoff, Elizabeth D.;
Tainer, John A.;
Kulm, Leslie A.

Publication type:

Article

Computational, pulse-radiolytic, and structural investigations of lysine-136 and its role in the electrostatic triad of human C u,Z n superoxide dismutase.

Published in:

Proteins, 1997, v. 29, n. 1, p. 103, doi. 10.1002/(SICI)1097-0134(199709)29:1<103::AID-PROT8>3.0.CO;2-G

By:

Fisher, Cindy L.;
Cabelli, Diane E.;
Hallewell, Robert A.;
Beroza, Paul;
Lo, Terence P.;
Getzoff, Elizabeth D.;
Tainer, John A.

Publication type:

Article

Atomic and residue hydrophilicity in the context of folded protein structures.

Published in:

Proteins, 1995, v. 23, n. 4, p. 536, doi. 10.1002/prot.340230408

By:

Kuhn, Leslie A.;
Swanson, Craig A.;
Pique, Michael E.;
Tainer, John A.;
Getzoff, Elizabeth D.

Publication type:

Article

Purification and crystallization of a schistosomal glutathione S-Transferase.

Published in:

Proteins, 1995, v. 22, n. 1, p. 55, doi. 10.1002/prot.340220108

By:

McTigue, Michele A.;
Bernstein, Susan L.;
Williams, DeWight R.;
Tainer, John A.

Publication type:

Article

Crystallization and preliminary crystallographic study of human CksHs1: A cell cycle regulatory protein.

Published in:

Proteins, 1995, v. 21, n. 1, p. 70, doi. 10.1002/prot.340210109

By:

Arvai, Andrew S.;
Bourne, Yves;
Williams, DeWight;
Reed, Steve I.;
Tainer, John A.

Publication type:

Article

Predicting molecular interactions and inducible complementarity: Fragment docking of fab-peptide complexes.

Published in:

Proteins, 1994, v. 20, n. 1, p. 15, doi. 10.1002/prot.340200104

By:

Friedman, Alan R.;
Roberts, Victoria A.;
Tainer, John A.

Publication type:

Article

The role of arginine 143 in the electrostatics and mechanism of Cu, Zn superoxide dismutase: Computational and experimental evaluation by mutational analysis.

Published in:

Proteins, 1994, v. 19, n. 1, p. 24, doi. 10.1002/prot.340190105

By:

Fisher, Cindy L.;
Cabelli, Diane E.;
Tainer, John A.;
Hallewell, Robert A.;
Getzoff, Elizabeth D.

Publication type:

Article

Evolution of CuZn superoxide dismutase and the Greek Key β-barrel structural motif.

Published in:

Proteins, 1989, v. 5, n. 4, p. 322, doi. 10.1002/prot.340050408

By:

Getzoff, Elizabeth D.;
Tainer, John A.;
Stempien, Michelle M.;
Bell, Graeme I.;
Hallewell, Robert A.

Publication type:

Article

NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism.

Published in:

EMBO Journal, 2025, v. 44, n. 4, p. 1220, doi. 10.1038/s44318-024-00360-6

By:

Brosey, Chris A;
Shen, Runze;
Tainer, John A

Publication type:

Article

ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.

Published in:

EMBO Journal, 2016, v. 35, n. 7, p. 791, doi. 10.15252/embj.201694047

By:

Deshpande, Rajashree A;
Williams, Gareth J;
Limbo, Oliver;
Williams, R Scott;
Kuhnlein, Jeff;
Lee, Ji‐Hoon;
Classen, Scott;
Guenther, Grant;
Russell, Paul;
Tainer, John A;
Paull, Tanya T

Publication type:

Article

The R-factor gap in macromolecular crystallography: an untapped potential for insights on accurate structures.

Published in:

FEBS Journal, 2014, v. 281, n. 18, p. 4046, doi. 10.1111/febs.12922

By:

Holton, James M.;
Classen, Scott;
Frankel, Kenneth A.;
Tainer, John A.

Publication type:

Article