Works matching AU Tainer, John A.

Results: 134

Structural basis for recognition of 5?-phosphotyrosine adducts by Tdp2.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 12, p. 1372, doi. 10.1038/nsmb.2423

By:

Shi, Ke;
Kurahashi, Kayo;
Gao, Rui;
Tsutakawa, Susan E;
Tainer, John A;
Pommier, Yves;
Aihara, Hideki

Publication type:

Article

Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 6, p. 653, doi. 10.1038/nsmb.2305

By:

Kim, In-Kwon;
Kiefer, James R;
Ho, Chris M W;
Stegeman, Roderick A;
Classen, Scott;
Tainer, John A;
Ellenberger, Tom

Publication type:

Article

ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 3, p. 364, doi. 10.1038/nsmb0312-364a

By:

Williams, Gareth J;
Williams, R Scott;
Williams, Jessica S;
Moncalian, Gabriel;
Arvai, Andrew S;
Limbo, Oliver;
Guenther, Grant;
SilDas, Soumita;
Hammel, Michal;
Russell, Paul;
Tainer, John A

Publication type:

Article

ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.

Published in:

2011

By:

Williams, Gareth J.;
Williams, R. Scott;
Williams, Jessica S.;
Moncalian, Gabriel;
Arvai, Andrew S.;
Limbo, Oliver;
Guenther, Grant;
SilDas, Soumita;
Hammel, Michal;
Russell, Paul;
Tainer, John A.

Publication type:

Correction Notice

ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 4, p. 423, doi. 10.1038/nsmb.2038

By:

Williams, Gareth J.;
Williams, R. Scott;
Williams, Jessica S.;
Moncalian, Gabriel;
Arvai, Andrew S.;
Limbo, Oliver;
Guenther, Grant;
SilDas, Soumita;
Hammel, Michal;
Russell, Paul;
Tainer, John A.

Publication type:

Article

Molecular mimicry of SUMO promotes DNA repair.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 5, p. 509, doi. 10.1038/nsmb.1582

By:

Prudden, John;
Perry, J. Jefferson P.;
Arvai, Andrew S.;
Tainer, John A.;
Boddy, Michael N.

Publication type:

Article

Structures of endonuclease V with DNA reveal initiation of deaminated adenine repair.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 2, p. 138, doi. 10.1038/nsmb.1538

By:

Dalhus, Bjørn;
Arvai, Andrew S;
Rosnes, Ida;
Olsen, Øyvind E;
Backe, Paul H;
Alseth, Ingrun;
Gao, Honghai;
Cao, Weiguo;
Tainer, John A;
Bjørås, Magnar

Publication type:

Article

DNA apurinic-apyrimidinic site binding and excision by endonuclease IV.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 5, p. 515, doi. 10.1038/nsmb.1414

By:

Garcin, Elsa D.;
Hosfield, David J.;
Desai, Sunil A.;
Haas, Brian J.;
Björas, Magnar;
Cunningham, Richard P.;
Tainer, John A.

Publication type:

Article

WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 5, p. 414, doi. 10.1038/nsmb1088

By:

Perry, J Jefferson P;
Yannone, Steven M;
Holden, Lauren G;
Hitomi, Chiharu;
Asaithamby, Aroumougame;
Han, Seungil;
Cooper, Priscilla K;
Chen, David J;
Tainer, John A

Publication type:

Article

Type IV pilus structure and bacterial pathogenicity.

Published in:

Nature Reviews Microbiology, 2004, v. 2, n. 5, p. 363, doi. 10.1038/nrmicro885

By:

Craig, Lisa;
Pique, Michael E.;
Tainer, John A.

Publication type:

Article

Distinct sequence features underlie microdeletions and gross deletions in the human genome.

Published in:

Human Mutation, 2022, v. 43, n. 3, p. 328, doi. 10.1002/humu.24314

By:

Qi, Mengling;
Stenson, Peter D.;
Ball, Edward V.;
Tainer, John A.;
Bacolla, Albino;
Kehrer‐Sawatzki, Hildegard;
Cooper, David N.;
Zhao, Huiying

Publication type:

Article

Characterizing flexible and intrinsically unstructured biological macromolecules by SAS using the Porod-Debye law.

Published in:

Biopolymers, 2011, v. 95, n. 8, p. 559, doi. 10.1002/bip.21638

By:

Rambo, Robert P.;
Tainer, John A.

Publication type:

Article

Mobility and evolutionary variability factors in protein antigenicity (reply).

Published in:

Nature, 1985, v. 317, n. 6032, p. 90, doi. 10.1038/317090b0

By:

TAINER, JOHN A.;
GETZOFF, ELIZABETH D.;
ALEXANDER, HANNAH;
HOUGHTEN, RICHARD A.;
OLSON, ARTHUR J.;
LERNER, RICHARD A.

Publication type:

Article

The reactivity of anti-peptide antibodies is a function of the atomic mobility of sites in a protein.

Published in:

Nature, 1984, v. 312, n. 5990, p. 127, doi. 10.1038/312127a0

By:

Tainer, John A.;
Getzoff, Elizabeth D.;
Alexander, Hannah;
Houghten, Richard A.;
Olson, Arthur J.;
Lerner, Richard A.;
Hendrickson, Wayne A.

Publication type:

Article

Cancer, cadmium and genome integrity.

Published in:

Nature Genetics, 2003, v. 34, n. 3, p. 239, doi. 10.1038/ng0703-239

By:

McMurray, Cynthia T;
Tainer, John A

Publication type:

Article

Molecular biology: DNA repair without flipping out.

Published in:

Nature, 2015, v. 527, n. 7577, p. 168, doi. 10.1038/nature15646

By:

Shin, David S.;
Tainer, John A.

Publication type:

Article

2017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update.

Published in:

Acta Crystallographica: Section D, Structural Biology, 2017, v. 73, n. 9, p. 710, doi. 10.1107/S2059798317011597

By:

Trewhella, Jill;
Duff, Anthony P.;
Durand, Dominique;
Gabel, Frank;
Guss, J. Mitchell;
Hendrickson, Wayne A.;
Hura, Greg L.;
Jacques, David A.;
Kirby, Nigel M.;
Kwan, Ann H.;
Pérez, Javier;
Pollack, Lois;
Ryan, Timothy M.;
Sali, Andrej;
Schneidman-Duhovny, Dina;
Schwede, Torsten;
Svergun, Dmitri I.;
Sugiyama, Masaaki;
Tainer, John A.;
Vachette, Patrice

Publication type:

Article

The pilus and porin of Neisseria gonorrhoeae cooperatively induce Ca2+ transients in infected epithelial cells.

Published in:

Cellular Microbiology, 2005, v. 7, n. 12, p. 1736, doi. 10.1111/j.1462-5822.2005.00586.x

By:

Ayala, Patricia;
Wilbur, J. Scott;
Wetzler, Lee M.;
Tainer, John A.;
Snyder, Aurelie;
So, Magdalene

Publication type:

Article

The pilus-induced Ca[sup2+] flux triggers lysosome exocytosis and increases the amount of Lamp1 accessible to Neisseria IgA1 protease.

Published in:

Cellular Microbiology, 2001, v. 3, n. 4, p. 265, doi. 10.1046/j.1462-5822.2001.00112.x

By:

Ayala, B. Patricia;
Vasquez, Brandi;
Clary, Susan;
Tainer, John A.;
Rodland, Karin;
So, Magdalene

Publication type:

Article

NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism.

Published in:

EMBO Journal, 2025, v. 44, n. 4, p. 1220, doi. 10.1038/s44318-024-00360-6

By:

Brosey, Chris A;
Shen, Runze;
Tainer, John A

Publication type:

Article

A Phase‐Separating Molecular Tether for Lariat Debranching Enzyme is Defective in Non‐Photosensitive Trichothiodystrophy.

Published in:

FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.02893

By:

Townley, Brittany;
Schmidt, Nicholas;
Holehouse, Alex;
Bacolla, Albino;
Srivatsan, Sridhar;
Walter, Matthew;
Tainer, John;
Mosammaparast, Nima

Publication type:

Article

A novel light, oxygen, or voltage fluorescent tag for structural and biophysical analysis of DNA repair enzymes (989.1).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.989.1

By:

Robertson, Molly;
Hatherill, Robert;
Fuss, Jill;
Tainer, John

Publication type:

Article

It takes two to tango: fine‐tuning of soluble guanylate cyclase activity via protein‐protein interactions and conformational changes (969.3).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.969.3

By:

Garcin, Elsa;
Seeger, Franziska;
Quintyn, Royston;
Tanimoto, Akiko;
Williams, Garrett;
Tsutakawa, Susan;
Wysocki, Vicki;
Tainer, John

Publication type:

Article

XRCC4 Protein Interactions with XRCC4‐like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break Repair.

Published in:

FASEB Journal, 2013, v. 27, p. 758.8, doi. 10.1096/fasebj.27.1_supplement.758.8

By:

Hammel, Michal;
Rey, Martial;
Yu, Yaping;
Lees‐Miller, Susan;
Tainer, John

Publication type:

Article

DNA binding and nucleotide flipping by the human DNA repair protein AGT.

Published in:

Nature Structural & Molecular Biology, 2004, v. 11, n. 8, p. 714, doi. 10.1038/nsmb791

By:

Daniels, Douglas S.;
Woo, Tammy T.;
Luu, Kieu X.;
Noll, David M.;
Clarke, Neil D.;
Pegg, Anthony E.;
Tainer, John A.

Publication type:

Article

Vibrio cholerae El Tor TcpA crystal structure and mechanism for pilus-mediated microcolony formation.

Published in:

Molecular Microbiology, 2010, v. 77, n. 3, p. 755, doi. 10.1111/j.1365-2958.2010.07244.x

By:

Lim, Mindy S.;
Ng, Dixon;
ZuSheng Zong;
Arvai, Andrew S.;
Taylor, Ronald K.;
Tainer, John A.;
Craig, Lisa

Publication type:

Article

Dynamic conformational switching underlies TFIIH function in transcription and DNA repair and impacts genetic diseases.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38416-6

By:

Yu, Jina;
Yan, Chunli;
Dodd, Thomas;
Tsai, Chi-Lin;
Tainer, John A.;
Tsutakawa, Susan E.;
Ivanov, Ivaylo

Publication type:

Article

All Stressed Out Without ATM Kinase.

Published in:

Science Signaling, 2011, v. 4, n. 167, p. 1, doi. 10.1126/scisignal.2001961

By:

Perry, J. Jefferson P.;
Tainer, John A.

Publication type:

Article

XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair1.

Published in:

Biochemistry & Cell Biology, 2013, v. 91, n. 1, p. 31, doi. 10.1139/bcb-2012-0058

By:

Mahaney, Brandi L.;
Hammel, Michal;
Meek, Katheryn;
Tainer, John A.;
Lees-Miller, Susan P.

Publication type:

Article

Mre11–Rad50–Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.

Published in:

Biochemistry & Cell Biology, 2007, v. 85, n. 4, p. 509, doi. 10.1139/O07-069

By:

Williams, R. Scott;
Williams, Jessica S.;
Tainer, John A.

Publication type:

Article

Coprinus cinereus rad50 Mutants Reveal an Essential Structural Role for Rad50 in Axial Element and Synaptonemal Complex Formation, Homolog Pairing and Meiotic Recombination.

Published in:

Genetics, 2008, v. 180, n. 4, p. 1889, doi. 10.1534/genetics.108.092775

By:

Acharya, Sonia N.;
Many, Alexander M.;
Schroeder, Andrew P.;
Kennedy, Felicia M.;
Savytskyy, Oleksandr P.;
Grubb, Jennifer T.;
Vincent, Jack A.;
Friedlle, Elizabeth A.;
Celerin, Martina;
Maillet, Daniel S.;
Palmerini, Heather J.;
Greischar, Megan A.;
Moncalian, Gabriel;
Williams, R. Scott;
Tainer, John A.;
Zolan, Miriam E.

Publication type:

Article

Cell-free expression of functional receptor tyrosine kinases.

Published in:

Scientific Reports, 2015, p. 12896, doi. 10.1038/srep12896

By:

He, Wei;
Scharadin, Tiffany M.;
Saldana, Matthew;
Gellner, Candice;
Hoang-Phou, Steven;
Takanishi, Christina;
Hura, Gregory L.;
Tainer, John A;
Carraway III, Kermit L.;
Henderson, Paul T.;
Coleman, Matthew A.

Publication type:

Article

Two novel SOD1 mutations in patients with familial amyotrophic lateral sclerosis.

Published in:

Human Molecular Genetics, 1995, v. 4, n. 6, p. 1113

By:

Deng, Han-Xiang;
Tainer, John A.;
Mitsumoto, Hiroshi;
Ohnishi, Akio;
He, Xiaoxuan;
Hung, Wu-Yen;
Zhao, Yaliang;
Juneja, Tony;
Hentati, Afif;
Siddique, Teepu

Publication type:

Article

Author Correction: Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05295-1

By:

Hou-Fu Guo;
Chi-Lin Tsai;
Masahiko Terajima;
Xiaochao Tan;
Banerjee, Priyam;
Miller, Mitchell D.;
Xin Liu;
Jiang Yu;
Byemerwa, Jovita;
Alvarado, Sarah;
Kaoud, Tamer S.;
Dalby, Kevin N.;
Bota-Rabassedas, Neus;
Yulong Chen;
Mitsuo Yamauchi;
Tainer, John A.;
Phillips Jr., George N.;
Kurie, Jonathan M.

Publication type:

Article

Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-02859-z

By:

Hou-Fu Guo;
Chi-Lin Tsai;
Masahiko Terajima;
Xiaochao Tan;
Banerjee, Priyam;
Miller, Mitchell D.;
Xin Liu;
Jiang Yu;
Byemerwa, Jovita;
Alvarado, Sarah;
Kaoud, Tamer S.;
Dalby, Kevin N.;
Bota-Rabassedas, Neus;
Yulong Chen;
Mitsuo Yamauchi;
Tainer, John A.;
Phillips Jr., George N.;
Kurie, Jonathan M.

Publication type:

Article

Characterization of the electrophile binding site and substrate binding mode of the 26-kDa glutathione S-transferase from Schistosoma japonicum.

Published in:

Proteins, 2003, v. 51, n. 1, p. 137, doi. 10.1002/prot.10345

By:

Rosa M.F. Cardoso;
Douglas S. Daniels;
Christopher M. Bruns;
John A. Tainer

Publication type:

Article

Screening a Peptidyl Database for Potential Ligands to Proteins With Side-Chain Flexibility

Published in:

Proteins, 1998, v. 33, n. 1, p. 74

By:

Schnecke, Volker;
Swanson, Craig A.;
Getzoff, Elizabeth D.;
Tainer, John A.;
Kulm, Leslie A.

Publication type:

Article

Computational, pulse-radiolytic, and structural investigations of lysine-136 and its role in the electrostatic triad of human C u,Z n superoxide dismutase.

Published in:

Proteins, 1997, v. 29, n. 1, p. 103, doi. 10.1002/(SICI)1097-0134(199709)29:1<103::AID-PROT8>3.0.CO;2-G

By:

Fisher, Cindy L.;
Cabelli, Diane E.;
Hallewell, Robert A.;
Beroza, Paul;
Lo, Terence P.;
Getzoff, Elizabeth D.;
Tainer, John A.

Publication type:

Article

Atomic and residue hydrophilicity in the context of folded protein structures.

Published in:

Proteins, 1995, v. 23, n. 4, p. 536, doi. 10.1002/prot.340230408

By:

Kuhn, Leslie A.;
Swanson, Craig A.;
Pique, Michael E.;
Tainer, John A.;
Getzoff, Elizabeth D.

Publication type:

Article

Purification and crystallization of a schistosomal glutathione S-Transferase.

Published in:

Proteins, 1995, v. 22, n. 1, p. 55, doi. 10.1002/prot.340220108

By:

McTigue, Michele A.;
Bernstein, Susan L.;
Williams, DeWight R.;
Tainer, John A.

Publication type:

Article

Crystallization and preliminary crystallographic study of human CksHs1: A cell cycle regulatory protein.

Published in:

Proteins, 1995, v. 21, n. 1, p. 70, doi. 10.1002/prot.340210109

By:

Arvai, Andrew S.;
Bourne, Yves;
Williams, DeWight;
Reed, Steve I.;
Tainer, John A.

Publication type:

Article

Predicting molecular interactions and inducible complementarity: Fragment docking of fab-peptide complexes.

Published in:

Proteins, 1994, v. 20, n. 1, p. 15, doi. 10.1002/prot.340200104

By:

Friedman, Alan R.;
Roberts, Victoria A.;
Tainer, John A.

Publication type:

Article

The role of arginine 143 in the electrostatics and mechanism of Cu, Zn superoxide dismutase: Computational and experimental evaluation by mutational analysis.

Published in:

Proteins, 1994, v. 19, n. 1, p. 24, doi. 10.1002/prot.340190105

By:

Fisher, Cindy L.;
Cabelli, Diane E.;
Tainer, John A.;
Hallewell, Robert A.;
Getzoff, Elizabeth D.

Publication type:

Article

Evolution of CuZn superoxide dismutase and the Greek Key β-barrel structural motif.

Published in:

Proteins, 1989, v. 5, n. 4, p. 322, doi. 10.1002/prot.340050408

By:

Getzoff, Elizabeth D.;
Tainer, John A.;
Stempien, Michelle M.;
Bell, Graeme I.;
Hallewell, Robert A.

Publication type:

Article

DNA Repair and Global Sumoylation Are Regulated by Distinct Ubc9 Noncovalent Complexes.

Published in:

Molecular & Cellular Biology, 2011, v. 31, n. 11, p. 2299, doi. 10.1128/MCB.05188-11

By:

Prudden, John;
Perry, J. Jefferson P.;
Minghua Nie;
Vashisht, Ajay A.;
Arvai, Andrew S.;
Hitomi, Chiharu;
Guenther, Grant;
Wohlschlegel, James A.;
Tainer, John A.;
Boddy, Michael N.

Publication type:

Article

Cracking tyrosine phosphatases.

Published in:

Nature, 1994, v. 370, n. 6490, p. 506, doi. 10.1038/370506a0

By:

Tainer, John;
Russell, Paul

Publication type:

Article

RNF4 interacts with both SUMO and nucleosomes to promote the DNA damage response.

Published in:

EMBO Reports, 2014, v. 15, n. 5, p. 601, doi. 10.1002/embr.201338369

By:

Groocock, Lynda M;
Nie, Minghua;
Prudden, John;
Moiani, Davide;
Wang, Tao;
Cheltsov, Anton;
Rambo, Robert P;
Arvai, Andrew S;
Hitomi, Chiharu;
Tainer, John A;
Luger, Karolin;
Perry, J Jefferson P;
Lazzerini‐Denchi, Eros;
Boddy, Michael N

Publication type:

Article

The nucleotide-dependent interaction of FlaH and FlaI is essential for assembly and function of the archaellum motor.

Published in:

Molecular Microbiology, 2016, v. 99, n. 4, p. 674, doi. 10.1111/mmi.13260

By:

Chaudhury, Paushali;
Neiner, Tomasz;
D'Imprima, Edoardo;
Banerjee, Ankan;
Reindl, Sophia;
Ghosh, Abhrajyoti;
Arvai, Andrew S.;
Mills, Deryck J.;
Does, Chris;
Tainer, John A.;
Vonck, Janet;
Albers, Sonja‐Verena

Publication type:

Article

Design of a monomeric human glutathione transferase GSTP1, a structurally stable but catalytically inactive protein.

Published in:

Protein Engineering, 2002, v. 15, n. 10, p. 827, doi. 10.1093/protein/15.10.827

By:

Abdalla, Abdel-Monem;
Bruns, Christopher M.;
Tainer, John A.;
Mannervik, Bengt;
Stenberg, Gun

Publication type:

Article

The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome.

Published in:

Cell Cycle, 2011, v. 10, n. 12, p. 1998, doi. 10.4161/cc.10.12.15878

By:

Trego, Kelly S.;
Chernikova, Sophia B.;
Davalos, Albert R.;
Perry, J. Jefferson P.;
Finger, L. David;
Ng, Cliff;
Tsai, Miaw-Sheue;
Yannone, Steven M.;
Tainer, John A.;
Campisi, Judith;
Cooper, Priscilla K.

Publication type:

Article