Works by Tachibana, Tatsuhiko

Results: 20

Robust and reproducible human intestinal organoid-derived monolayer model for analyzing drug absorption.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-95823-z

By:

Tanaka, Kai;
Mochizuki, Tatsuki;
Baba, Shogo;
Kawai, Shigeto;
Nakano, Kiyotaka;
Tachibana, Tatsuhiko;
Uchimura, Kohsuke;
Kato, Atsuhiko;
Miyayama, Takashi;
Yamaguchi, Tomohito;
Nishihara, Hiroshi;
Terao, Kimio;
Kato, Yasutaka

Publication type:

Article

Recent Advances in Translational Pharmacokinetics and Pharmacodynamics Prediction of Therapeutic Antibodies Using Modeling and Simulation.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 5, p. 508, doi. 10.3390/ph15050508

By:

Haraya, Kenta;
Tsutsui, Haruka;
Komori, Yasunori;
Tachibana, Tatsuhiko

Publication type:

Article

Analysis of Non-linear Pharmacokinetics of P-Glycoprotein Substrates in a Microfluidic Device Using a Mathematical Model that Includes an Unstirred Water Layer (UWL) Compartment.

Published in:

Pharmaceutical Research, 2021, v. 38, n. 6, p. 1031, doi. 10.1007/s11095-021-03054-4

By:

Igarashi, Fumihiko;
Nakagawa, Toshito;
Shinohara, Yuka;
Tachibana, Tatsuhiko

Publication type:

Article

Regulation of <it>CAPRICE</it> Transcription by MYB Proteins for Root Epidermis Differentiation in <it>Arabidopsis</it>.

Published in:

Plant & Cell Physiology, 2005, v. 46, n. 6, p. 817, doi. 10.1093/pcp/pci096

By:

Koshino-Kimura, Yoshihiro;
Wada, Takuji;
Tachibana, Tatsuhiko;
Tsugeki, Ryuji;
Ishiguro, Sumie;
Okada, Kiyotaka

Publication type:

Article

Quantitative prediction of P‐glycoprotein‐mediated drug–drug interactions and intestinal absorption using humanized mice.

Published in:

British Journal of Pharmacology, 2021, v. 178, n. 21, p. 4335, doi. 10.1111/bph.15612

By:

Miyake, Taiji;
Tsutsui, Haruka;
Haraya, Kenta;
Tachibana, Tatsuhiko;
Morimoto, Kayoko;
Takehara, Shoko;
Ayabe, Miho;
Kobayashi, Kaoru;
Kazuki, Yasuhiro

Publication type:

Article

A Novel Total Drug Assay for Quantification of Anti-C5 Therapeutic Monoclonal Antibody in the Presence of Abundant Target.

Published in:

AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00539-9

By:

Watanabe, Hiroo;
Shibuya, Mitsuko;
Shibahara, Norihito;
Ruike, Yoshinao;
Sampei, Zenjiro;
Haraya, Kenta;
Tachibana, Tatsuhiko;
Wakabayashi, Tetsuya;
Sakamoto, Akihisa;
Tsunoda, Hiroyuki;
Murao, Naoaki

Publication type:

Article

Prediction of Nonlinear Intestinal Absorption of CYP3A4 and P-Glycoprotein Substrates from their In Vitro Km Values.

Published in:

Pharmaceutical Research, 2012, v. 29, n. 3, p. 651, doi. 10.1007/s11095-011-0579-2

By:

Tachibana, Tatsuhiko;
Kato, Motohiro;
Sugiyama, Yuichi

Publication type:

Article

Model Analysis of the Concentration-Dependent Permeability of P-gp Substrates.

Published in:

Pharmaceutical Research, 2010, v. 27, n. 3, p. 442, doi. 10.1007/s11095-009-0026-9

By:

Tachibana, Tatsuhiko;
Kitamura, Satoshi;
Kato, Motohiro;
Mitsui, Tetsuya;
Shirasaka, Yoshiyuki;
Yamashita, Shinji;
Sugiyama, Yuichi

Publication type:

Article

Estimation of Clearance and Bioavailability of Therapeutic Monoclonal Antibodies from Only Subcutaneous Injection Data in Humans Based on Comprehensive Analysis of Clinical Data.

Published in:

Clinical Pharmacokinetics, 2021, v. 60, n. 10, p. 1325, doi. 10.1007/s40262-021-01023-z

By:

Haraya, Kenta;
Tachibana, Tatsuhiko

Publication type:

Article

Simple Approach to Accurately Predict Pharmacokinetics of Therapeutic Monoclonal Antibodies after Subcutaneous Injection in Humans.

Published in:

Clinical Pharmacokinetics, 2021, v. 60, n. 1, p. 111, doi. 10.1007/s40262-020-00917-8

By:

Haraya, Kenta;
Tachibana, Tatsuhiko

Publication type:

Article

Quantitative prediction of CYP3A‐mediated drug–drug interactions by correctly estimating fraction metabolized using human liver chimeric mice.

Published in:

British Journal of Pharmacology, 2024, v. 181, n. 7, p. 1091, doi. 10.1111/bph.16270

By:

Miyake, Taiji;
Mochizuki, Tatsuki;
Nakagawa, Toshito;
Nakamura, Mikiko;
Emoto, Chie;
Komiyama, Natsuko;
Hirabayashi, Manabu;
Tsuruta, Satoshi;
Shimojo, Tomofumi;
Terao, Kimio;
Tachibana, Tatsuhiko

Publication type:

Article

Antibody engineering to generate SKY59, a long-acting anti-C5 recycling antibody.

Published in:

PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0209509

By:

Sampei, Zenjiro;
Haraya, Kenta;
Tachibana, Tatsuhiko;
Fukuzawa, Taku;
Shida-Kawazoe, Meiri;
Gan, Siok Wan;
Shimizu, Yuichiro;
Ruike, Yoshinao;
Feng, Shu;
Kuramochi, Taichi;
Muraoka, Masaru;
Kitazawa, Takehisa;
Kawabe, Yoshiki;
Igawa, Tomoyuki;
Hattori, Kunihiro;
Nezu, Junichi

Publication type:

Article

Translational Approach for Predicting Human Pharmacokinetics of Engineered Therapeutic Monoclonal Antibodies with Increased FcRn-Binding Mutations.

Published in:

BioDrugs, 2023, v. 37, n. 1, p. 99, doi. 10.1007/s40259-022-00566-2

By:

Haraya, Kenta;
Tachibana, Tatsuhiko

Publication type:

Article

Engineered Monoclonal Antibody with Novel Antigen-Sweeping Activity <i>In Vivo</i>

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063236

By:

Igawa, Tomoyuki;
Maeda, Atsuhiko;
Haraya, Kenta;
Tachibana, Tatsuhiko;
Iwayanagi, Yuki;
Mimoto, Futa;
Higuchi, Yoshinobu;
Ishii, Shinya;
Tamba, Shigero;
Hironiwa, Naoka;
Nagano, Kozue;
Wakabayashi, Tetsuya;
Tsunoda, Hiroyuki;
Hattori, Kunihiro

Publication type:

Article

Identification and Multidimensional Optimization of an Asymmetric Bispecific IgG Antibody Mimicking the Function of Factor VIII Cofactor Activity.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0057479

By:

Sampei, Zenjiro;
Igawa, Tomoyuki;
Soeda, Tetsuhiro;
Okuyama-Nishida, Yukiko;
Moriyama, Chifumi;
Wakabayashi, Tetsuya;
Tanaka, Eriko;
Muto, Atsushi;
Kojima, Tetsuo;
Kitazawa, Takehisa;
Yoshihashi, Kazutaka;
Harada, Aya;
Funaki, Miho;
Haraya, Kenta;
Tachibana, Tatsuhiko;
Suzuki, Sachiyo;
Esaki, Keiko;
Nabuchi, Yoshiaki;
Hattori, Kunihiro

Publication type:

Article

Predicting pharmacokinetic profile of therapeutic antibodies after iv injection from only the data after sc injection in cynomolgus monkey.

Published in:

Xenobiotica, 2017, v. 47, n. 3, p. 194, doi. 10.1080/00498254.2016.1174792

By:

Haraya, Kenta;
Tachibana, Tatsuhiko;
Nezu, Junichi

Publication type:

Article

Application of human FcRn transgenic mice as a pharmacokinetic screening tool of monoclonal antibody.

Published in:

Xenobiotica, 2014, v. 44, n. 12, p. 1127, doi. 10.3109/00498254.2014.941963

By:

Haraya, Kenta;
Tachibana, Tatsuhiko;
Nanami, Masahiko;
Ishigai, Masaki

Publication type:

Article

Elimination of plasma soluble antigen in cynomolgus monkeys by combining pH-dependent antigen binding and novel Fc engineering.

Published in:

2022

By:

Hori, Yuji;
Ohmine, Ken;
Katada, Hitoshi;
Noguchi, Yuki;
Sato, Kazuki;
Nambu, Takeru;
Adeline, Lam Runyi;
Wan, Gan Siok;
Haraya, Kenta;
Ozeki, Kazuhisa;
Nanami, Masahiko;
Tachibana, Tatsuhiko;
Sampei, Zenjiro;
Kuramochi, Taichi;
Nezu, Junichi;
Hattori, Kunihiro;
Igawa, Tomoyuki

Publication type:

Report

Identification of human IgG1 variant with enhanced FcRn binding and without increased binding to rheumatoid factor autoantibody.

Published in:

mAbs (1942-0862), 2017, v. 9, n. 5, p. 844, doi. 10.1080/19420862.2017.1314873

By:

Maeda, Atsuhiko;
Iwayanagi, Yuki;
Haraya, Kenta;
Tachibana, Tatsuhiko;
Nakamura, Genki;
Nambu, Takeru;
Esaki, Keiko;
Hattori, Kunihiro;
Igawa, Tomoyuki

Publication type:

Article

Antibody recycling by engineered pH-dependent antigen binding improves the duration of antigen neutralization.

Published in:

Nature Biotechnology, 2010, v. 28, n. 11, p. 1203, doi. 10.1038/nbt.1691

By:

Igawa, Tomoyuki;
Ishii, Shinya;
Tachibana, Tatsuhiko;
Maeda, Atsuhiko;
Higuchi, Yoshinobu;
Shimaoka, Shin;
Moriyama, Chifumi;
Watanabe, Tomoyuki;
Takubo, Ryoko;
Doi, Yoshiaki;
Wakabayashi, Tetsuya;
Hayasaka, Akira;
Kadono, Shoujiro;
Miyazaki, Takuya;
Haraya, Kenta;
Sekimori, Yasuo;
Kojima, Tetsuo;
Nabuchi, Yoshiaki;
Aso, Yoshinori;
Kawabe, Yoshiki

Publication type:

Article