OpenURL Connection Search

Select item for more details and to access through your institution.

HPV/E7 induces chemotherapy-mediated tumor suppression by ceramide-dependent mitophagy.
Published in:
EMBO Molecular Medicine, 2017, v. 9, n. 8, p. 1030, doi. 10.15252/emmm.201607088
By:
- Thomas, Raquela J;
- Oleinik, Natalia;
- Panneer Selvam, Shanmugam;
- Vaena, Silvia G;
- Dany, Mohammed;
- Nganga, Rose N;
- Depalma, Ryan;
- Baron, Kyla D;
- Kim, Jisun;
- Szulc, Zdzislaw M;
- Ogretmen, Besim
Publication type:
Article
Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis.
Published in:
EMBO Molecular Medicine, 2013, v. 5, n. 1, p. 105, doi. 10.1002/emmm.201201283
By:
- Saddoughi, Sahar A.;
- Gencer, Salih;
- Peterson, Yuri K.;
- Ward, Katherine E.;
- Mukhopadhyay, Archana;
- Oaks, Joshua;
- Bielawski, Jacek;
- Szulc, Zdzislaw M.;
- Thomas, Raquela J.;
- Selvam, Shanmugam P.;
- Senkal, Can E.;
- Garrett‐Mayer, Elizabeth;
- De Palma, Ryan M.;
- Fedarovich, Dzmitry;
- Liu, Angen;
- Habib, Amyn A.;
- Stahelin, Robert V.;
- Perrotti, Danilo;
- Ogretmen, Besim
Publication type:
Article
L-threo-C6-pyridinium-ceramide Bromide, a Novel Cationic Ceramide, Induces NADPH Oxidase Activation, Mitochondrial Dysfunction and Loss in Cell Viability in INS 832/13 β-cells.
Published in:
Cellular Physiology & Biochemistry (Karger AG), 2012, v. 30, n. 4, p. 1051, doi. 10.1159/000341481
By:
- Syeda, Ismail;
- Szulc, Zdzislaw M.;
- Ogretmen, Besim;
- Kowluru, Anjaneyulu
Publication type:
Article
Bax and Bcl-xL exert their regulation on different sites of the ceramide channel.
Published in:
Biochemical Journal, 2012, v. 445, n. 1, p. 81, doi. 10.1042/BJ20112103
By:
- PERERA, Meenu N.;
- LIN, Shang H.;
- PETERSON, Yuri K.;
- BIELAWSKA, Alicja;
- SZULC, Zdzislaw M.;
- BITTMAN, Robert;
- COLOMBINI, Marco
Publication type:
Article
Identification of C6-ceramide-interacting proteins in D6 P2 T Schwannoma cells.
Published in:
Proteomics, 2012, v. 12, n. 13, p. 2179, doi. 10.1002/pmic.201100527
By:
- Kota, Venkatesh;
- Szulc, Zdzislaw M.;
- Hama, Hiroko
Publication type:
Article
Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia.
Published in:
Cancers, 2023, v. 15, n. 24, p. 5866, doi. 10.3390/cancers15245866
By:
- Ung, Johnson;
- Tan, Su-Fern;
- Fox, Todd E.;
- Shaw, Jeremy J. P.;
- Taori, Maansi;
- Horton, Bethany J.;
- Golla, Upendarrao;
- Sharma, Arati;
- Szulc, Zdzislaw M.;
- Wang, Hong-Gang;
- Chalfant, Charles E.;
- Cabot, Myles C.;
- Claxton, David F.;
- Loughran Jr., Thomas P.;
- Feith, David J.
Publication type:
Article
The NMR-based characterization of the FTY720-SET complex reveals an alternative mechanism for the attenuation of the inhibitory SET-PP2A interaction.
Published in:
FASEB Journal, 2019, v. 33, n. 6, p. 7647, doi. 10.1096/fj.201802264R
By:
- De Palma, Ryan M.;
- Parnham, Stuart R.;
- Yitong Li;
- Oaks, Joshua J.;
- Peterson, Yuri K.;
- Szulc, Zdzislaw M.;
- Roth, Braden M.;
- Yongna Xing;
- Ogretmen, Besim
Publication type:
Article
Alkaline ceramidase 2 regulates ²1 integrin maturation and cell adhesion.
Published in:
FASEB Journal, 2009, v. 23, n. 2, p. 656, doi. 10.1096/fj.08-115634
By:
- Wei Sun;
- Wei Hu;
- Ruijuan Xu;
- Junfei Jin;
- Szulc, Zdzislaw M.;
- Guofeng Zhang;
- Galadari, Sehamuddin H.;
- Obeid, Lina M.;
- Cungui Mao
Publication type:
Article
Observation of different ceramide species from crude cellular extracts by normal-phase high-performance liquid chromatography coupled to atmospheric pressure chemical ionization mass spectrometry.
Published in:
Rapid Communications in Mass Spectrometry: RCM, 2003, v. 17, n. 11, p. 1203, doi. 10.1002/rcm.1043
By:
- Benjamin J. Pettus;
- Alicia Bielawska;
- Bart-Jan Kroesen;
- Peter D. R. Moeller;
- Zdzislaw M. Szulc;
- Yusuf A. Hannun;
- Mark Busman
Publication type:
Article
Upregulation of the Human Alkaline Ceramidase 1 and Acid Ceramidase Mediates Calcium-Induced Differentiation of Epidermal Keratinocytes.
Published in:
Journal of Investigative Dermatology, 2008, v. 128, n. 2, p. 389, doi. 10.1038/sj.jid.5701025
By:
- Wei Sun;
- Ruijuan Xu;
- Wei Hu;
- Junfei Jin;
- Crellin, Heather A.;
- Bielawski, Jacek;
- Szulc, Zdzislaw M.;
- Thiers, Bruce H.;
- Obeid, Lina M.;
- Cungui Mao
Publication type:
Article
Lysosomotropic acid ceramidase inhibitor induces apoptosis in prostate cancer cells.
Published in:
Cancer Chemotherapy & Pharmacology, 2008, v. 61, n. 2, p. 231, doi. 10.1007/s00280-007-0465-0
By:
- Holman, David H.;
- Turner, Lorianne S.;
- El-Zawahry, Ahmed;
- Elojeimy, Saeed;
- Xiang Liu;
- Bielawski, Jacek;
- Szulc, Zdzislaw M.;
- Norris, Kristi;
- Zeidan, Youssef H.;
- Hannun, Yusuf A.;
- Bielawska, Alicja;
- Norris, James S.
Publication type:
Article
Interaction of acid ceramidase inhibitor LCL521 with tumor response to photodynamic therapy and photodynamic therapy-generated vaccine.
Published in:
International Journal of Cancer, 2016, v. 139, n. 6, p. 1372, doi. 10.1002/ijc.30171
By:
- Korbelik, Mladen;
- Banáth, Judit;
- Zhang, Wei;
- Saw, Kyi Min;
- Szulc, Zdzislaw M.;
- Bielawska, Alicja;
- Separovic, Duska
Publication type:
Article
C16-ceramide is a natural regulatory ligand of p53 in cellular stress response.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06650-y
By:
- Fekry, Baharan;
- Jeffries, Kristen A.;
- Esmaeilniakooshkghazi, Amin;
- Szulc, Zdzislaw M.;
- Knagge, Kevin J.;
- Kirchner, David R.;
- Horita, David A.;
- Krupenko, Sergey A.;
- Krupenko, Natalia I.
Publication type:
Article
Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy.
Published in:
Nature Chemical Biology, 2012, v. 8, n. 12, p. 1008, doi. 10.1038/nchembio1212-1008c
By:
- Sentelle, R David;
- Senkal, Can E;
- Jiang, Wenhui;
- Ponnusamy, Suriyan;
- Gencer, Salih;
- Selvam, Shanmugam Panneer;
- Ramshesh, Venkat K;
- Peterson, Yuri K;
- Lemasters, John J;
- Szulc, Zdzislaw M;
- Bielawski, Jacek;
- Ogretmen, Besim
Publication type:
Article
Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy.
Published in:
Nature Chemical Biology, 2012, v. 8, n. 10, p. 831, doi. 10.1038/nchembio.1059
By:
- Sentelle, R David;
- Senkal, Can E;
- Jiang, Wenhui;
- Ponnusamy, Suriyan;
- Gencer, Salih;
- Panneer Selvam, Shanmugam;
- Ramshesh, Venkat K;
- Peterson, Yuri K;
- Lemasters, John J;
- Szulc, Zdzislaw M;
- Bielawski, Jacek;
- Ogretmen, Besim
Publication type:
Article
Alterations of lipid‐mediated mitophagy result in aging‐dependent sensorimotor defects.
Published in:
Aging Cell, 2023, v. 22, n. 10, p. 1, doi. 10.1111/acel.13954
By:
- Oleinik, Natalia;
- Albayram, Onder;
- Kassir, Mohamed Faisal;
- Atilgan, F. Cansu;
- Walton, Chase;
- Karakaya, Eda;
- Kurtz, John;
- Alekseyenko, Alexander;
- Alsudani, Habeeb;
- Sheridan, Megan;
- Szulc, Zdzislaw M.;
- Ogretmen, Besim
Publication type:
Article
Anticancer actions of lysosomally targeted inhibitor, LCL521, of acid ceramidase.
Published in:
PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0177805
By:
- Bai, Aiping;
- Mao, Cungui;
- Jenkins, Russell W.;
- Szulc, Zdzislaw M.;
- Bielawska, Alicja;
- Hannun, Yusuf A.
Publication type:
Article
Inhibition of growth and telomerase activity by novel cationic ceramide analogs with high solubility in human head and neck squamous cell carcinoma cells
Published in:
Otolaryngology-Head & Neck Surgery, 2005, v. 132, n. 1, p. 55, doi. 10.1016/j.otohns.2004.08.015
By:
- Rossi, Michael J.;
- Sundararaj, Kamala;
- Koybasi, Serap;
- Phillips, Monique S.;
- Szulc, Zdzislaw M.;
- Bielawska, Alicja;
- Day, Terry A.;
- Obeid, Lina M.;
- Hannun, Yusuf A.;
- Ogretmen, Besim
Publication type:
Article

Found: 18

HPV/E7 induces chemotherapy-mediated tumor suppression by ceramide-dependent mitophagy.

Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis.

L-threo-C<sub>6</sub>-pyridinium-ceramide Bromide, a Novel Cationic Ceramide, Induces NADPH Oxidase Activation, Mitochondrial Dysfunction and Loss in Cell Viability in INS 832/13 β-cells.

Bax and Bcl-xL exert their regulation on different sites of the ceramide channel.

Identification of C<sub>6</sub>-ceramide-interacting proteins in D6 P2 T Schwannoma cells.

Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia.

The NMR-based characterization of the FTY720-SET complex reveals an alternative mechanism for the attenuation of the inhibitory SET-PP2A interaction.

Alkaline ceramidase 2 regulates ²1 integrin maturation and cell adhesion.

Observation of different ceramide species from crude cellular extracts by normal-phase high-performance liquid chromatography coupled to atmospheric pressure chemical ionization mass spectrometry.

Upregulation of the Human Alkaline Ceramidase 1 and Acid Ceramidase Mediates Calcium-Induced Differentiation of Epidermal Keratinocytes.

Lysosomotropic acid ceramidase inhibitor induces apoptosis in prostate cancer cells.

Interaction of acid ceramidase inhibitor LCL521 with tumor response to photodynamic therapy and photodynamic therapy-generated vaccine.

C<sub>16</sub>-ceramide is a natural regulatory ligand of p53 in cellular stress response.

Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy.

Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy.

Alterations of lipid‐mediated mitophagy result in aging‐dependent sensorimotor defects.

Anticancer actions of lysosomally targeted inhibitor, LCL521, of acid ceramidase.

Inhibition of growth and telomerase activity by novel cationic ceramide analogs with high solubility in human head and neck squamous cell carcinoma cells