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Site-specific conjugation improves therapeutic index of antibody drug conjugates with high drug loading.
Published in:
Nature Biotechnology, 2015, v. 33, n. 7, p. 694, doi. 10.1038/nbt.3274
By:
- Strop, Pavel;
- Delaria, Kathy;
- Foletti, Davide;
- Witt, Jody Melton;
- Hasa-Moreno, Adela;
- Poulsen, Kris;
- Casas, Meritxell Galindo;
- Dorywalska, Magdalena;
- Farias, Santiago;
- Pios, Ariel;
- Lui, Victor;
- Dushin, Russell;
- Zhou, Dahui;
- Navaratnam, Thayalan;
- Tran, Thomas-Toan;
- Sutton, Janette;
- Lindquist, Kevin C;
- Han, Bora;
- Liu, Shu-Hui;
- Shelton, David L
Publication type:
Article
Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy.
Published in:
PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0132282
By:
- Dorywalska, Magdalena;
- Strop, Pavel;
- Melton-Witt, Jody A.;
- Hasa-Moreno, Adela;
- Farias, Santiago E.;
- Galindo Casas, Meritxell;
- Delaria, Kathy;
- Lui, Victor;
- Poulsen, Kris;
- Sutton, Janette;
- Bolton, Gary;
- Zhou, Dahui;
- Moine, Ludivine;
- Dushin, Russell;
- Tran, Thomas-Toan;
- Liu, Shu-Hui;
- Rickert, Mathias;
- Foletti, Davide;
- Shelton, David L.;
- Pons, Jaume
Publication type:
Article
Off-the-shelf AlloCAR T™ cells targeting BCMA for the treatment of multiple myeloma.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e24, doi. 10.1016/j.clml.2019.09.035
By:
- Sommer, Cesar;
- Bentley, Trevor;
- Sutton, Janette;
- Heyen, Jonathan;
- Valton, Julien;
- Ni, Yajin;
- Justewicz, Dominic;
- Van Blarcom, Thomas;
- Smith, Julianne;
- Leonard, Mark;
- Sasu, Barbra
Publication type:
Article

Found: 3

Site-specific conjugation improves therapeutic index of antibody drug conjugates with high drug loading.

Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy.

Off-the-shelf AlloCAR T™ cells targeting BCMA for the treatment of multiple myeloma.