Works by Sutherland, Calum

Results: 38

Correction: Glycogen Synthase Kinase-3 regulates IGFBP-1 gene transcription through the Thymine-rich Insulin Response Element.

Published in:

2024

By:

Finlay, David;
Patel, Satish;
Dickson, Lorna M.;
Shpiro, Natalia;
Marquez, Rodolfo;
Rhodes, Chris J.;
Sutherland, Calum

Publication type:

Correction Notice

Neuronal deletion of GSK3β increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2.

Published in:

BMC Biology, 2014, v. 12, n. 1, p. 1, doi. 10.1186/1741-7007-12-47

By:

Liz, Márcia A.;
Mar, Fernando M.;
Santos, Telma E.;
Pimentel, Helena I.;
Marques, Ana M.;
Morgado, Marlene M.;
Vieira, Sílvia;
Sousa, Vera F.;
Pemble, Hayley;
Wittmann, Torsten;
Sutherland, Calum;
Woodgett, James R.;
Sousa, Mónica M.

Publication type:

Article

Elraglusib (formerly 9-ING-41) possesses potent anti-lymphoma properties which cannot be attributed to GSK3 inhibition.

Published in:

Cell Communication & Signaling, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12964-023-01147-8

By:

Coats, Josh T.;
Tauro, Sudhir;
Sutherland, Calum

Publication type:

Article

Leptin and insulin stimulation of signalling pathways in arcuate nucleus neurones: PI3K dependent actin reorganization and K<sub>ATP</sub> channel activation.

Published in:

BMC Neuroscience, 2004, v. 5, p. 1, doi. 10.1186/1471-2202-5-54

By:

Mirshamsi, Shirin;
Laidlaw, Hilary A.;
Ke Ning;
Anderson, Erin;
Burgess, Laura A.;
Gray, Alexander;
Sutherland, Calum;
Ashford, Michael L. J.

Publication type:

Article

What Are the bona fide GSK3 Substrates?

Published in:

2011

By:

Sutherland, Calum

Publication type:

Journal Article

What Are the bona fide GSK3 Substrates?

Published in:

International Journal of Alzheimer's Disease, 2011, v. 2011, p. 1, doi. 10.4061/2011/505607

By:

Sutherland, Calum

Publication type:

Article

Dual regulation of transcription factor Nrf2 by Keap1 and by the combined actions of β-TrCP and GSK-3.

Published in:

Biochemical Society Transactions, 2015, v. 43, n. 4, p. 611, doi. 10.1042/BST20150011

By:

Hayes, John D.;
Chowdhry, Sudhir;
Dinkova-Kostova, Albena T.;
Sutherland, Calum

Publication type:

Article

Glycogen Synthase Kinase-3 regulates IGFBP-1 gene transcription through the Thymine-rich Insulin Response Element.

Published in:

BMC Molecular Biology, 2004, v. 5, p. 15, doi. 10.1186/1471-2199-5-15

By:

Finlay, David;
Patel, Satish;
Dickson, Lorna M.;
Shpiro, Natalia;
Marquez, Rodolfo;
Rhodes, Chris J.;
Sutherland, Calum

Publication type:

Article

Heat Shock Factor 1 Is a Substrate for p38 Mitogen-Activated Protein Kinases.

Published in:

Molecular & Cellular Biology, 2016, v. 36, n. 18, p. 2403, doi. 10.1128/MCB.00292-16

By:

Naidu, Sharadha Dayalan;
Sutherland, Calum;
Ying Zhang;
Risco, Ana;
de la Vega, Laureano;
Caunt, Christopher J.;
Hastie, C. James;
Lamont, Douglas J.;
Torrente, Laura;
Chowdhry, Sudhir;
Benjamin, Ivor J.;
Keyse, Stephen M.;
Cuenda, Ana;
Dinkova-Kostova, Albena T.

Publication type:

Article

CNP/cGMP signaling regulates axon branching and growth by modulating microtubule polymerization.

Published in:

Developmental Neurobiology (19328451), 2013, v. 73, n. 9, p. 673, doi. 10.1002/dneu.22078

By:

Xia, Caihong;
Nguyen, Minh;
Garrison, Amy K.;
Zhao, Zhen;
Wang, Zheng;
Sutherland, Calum;
Ma, Le

Publication type:

Article

Proinsulin is stable at room temperature for 24 hours in EDTA: A clinical laboratory analysis (adAPT 3).

Published in:

PLoS ONE, 2017, v. 12, n. 4, p. 1, doi. 10.1371/journal.pone.0171716

By:

Davidson, Jane;
McDonald, Timothy;
Sutherland, Calum;
Mostazir, Mohammod;
VanAalten, Lidy;
Wilkin, Terence

Publication type:

Article

New developments for prevention of type 1 diabetes: a paradigm shift?

Published in:

2019

By:

Schofield, Christopher J;
Sutherland, Calum

Publication type:

Editorial

CRMP2 Hyperphosphorylation is Characteristic of Alzheimer's Disease and not a Feature Common to Other Neurodegenerative Diseases.

Published in:

Journal of Alzheimer's Disease, 2011, v. 27, n. 3, p. 615, doi. 10.3233/JAD-2011-110617

By:

Williamson, Ritchie;
van Aalten, Lidy;
Mann, David M.A.;
Platt, Bettina;
Plattner, Florian;
Bedford, Lynn;
Mayer, John;
Howlett, David;
Usardi, Alessia;
Sutherland, Calum;
Cole, Adam R.

Publication type:

Article

A systematic review of evidence that environmental contaminant exposure impedes weight loss and glycemic control during calorie‐restricted diets in humans.

Published in:

Obesity Reviews, 2025, v. 26, n. 5, p. 1, doi. 10.1111/obr.13886

By:

Bennett, Kimberley Ann;
Sutherland, Calum;
Savage, Anne Louise

Publication type:

Article

Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles.

Published in:

Nature Neuroscience, 2010, v. 13, n. 7, p. 845, doi. 10.1038/nn.2571

By:

Clayton, Emma L.;
Sue, Nancy;
Smillie, Karen J,;
O'Leary, Timothy;
Bache, Nicolai;
Cheung, Giselle;
Cole, Adam R.;
Wyllie, David J.;
Sutherland, Calum;
Robinson, Phillip J.;
Cousin, Michael A.

Publication type:

Article

The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver.

Published in:

Nature Communications, 2014, v. 5, n. 8, p. 4535, doi. 10.1038/ncomms5535

By:

Patel, Kashyap;
Foretz, Marc;
Marion, Allison;
Campbell, David G.;
Gourlay, Robert;
Boudaba, Nadia;
Tournier, Emilie;
Titchenell, Paul;
Peggie, Mark;
Deak, Maria;
Wan, Min;
Kaestner, Klaus H.;
Göransson, Olga;
Viollet, Benoit;
Gray, Nathanael S.;
Birnbaum, Morris J.;
Sutherland, Calum;
Sakamoto, Kei

Publication type:

Article

The genetic association of the transcription factor NPAT with glycemic response to metformin involves regulation of fuel selection.

Published in:

PLoS ONE, 2021, v. 16, n. 7, p. 1, doi. 10.1371/journal.pone.0253533

By:

Chen, Changwei;
Gallagher, Jennifer R.;
Tarlton, Jamie;
van Aalten, Lidy;
Bray, Susan E.;
Ashford, Michael L. J.;
McCrimmon, Rory J.;
Pearson, Ewan R.;
McNeilly, Alison D.;
Sutherland, Calum

Publication type:

Article

Obesity-Induced Insulin Resistance in Human Skeletal Muscle Is Characterised by Defective Activation of p42/p44 MAP Kinase.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0056928

By:

Ruiz-Alcaraz, Antonio J.;
Lipina, Christopher;
Petrie, John R.;
Murphy, Michael J.;
Morris, Andrew D.;
Sutherland, Calum;
Cuthbertson, Daniel J.

Publication type:

Article

Recruitment, Retainment, and Biomarkers of Response; A Pilot Trial of Lithium in Humans With Mild Cognitive Impairment.

Published in:

Frontiers in Molecular Neuroscience, 2019, p. N.PAG, doi. 10.3389/fnmol.2019.00163

By:

Duthie, Ashleigh;
van Aalten, Lidy;
MacDonald, Cara;
McNeilly, Alison;
Gallagher, Jennifer;
Geddes, John;
Lovestone, Simon;
Sutherland, Calum

Publication type:

Article

GSK3β Regulates Myelin-Dependent Axon Outgrowth Inhibition through CRMP4.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 16, p. 5635, doi. 10.1523/JNEUROSCI.6154-09.2010

By:

Alabed, Yazan Z.;
Pool, Madeline;
Tone, Stephan Ong;
Sutherland, Calum;
Fournier, Alyson E.

Publication type:

Article

Phosphorylation of the N-terminus of Syntaxin-16 controls interaction with mVps45 and GLUT4 trafficking in adipocytes.

Published in:

PeerJ, 2023, p. 1, doi. 10.7717/peerj.15630

By:

Bremner, Shaun K.;
Berends, Rebecca;
Kaupisch, Alexandra;
Roccisana, Jennifer;
Sutherland, Calum;
Bryant, Nia J.;
Gould, Gwyn W.

Publication type:

Article

Reducing Glut2 throughout the body does not result in cognitive behaviour differences in aged male mice.

Published in:

BMC Research Notes, 2020, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13104-020-05276-y

By:

Morrice, Nicola;
van Aalten, Lidy;
McNeilly, Alison;
McCrimmon, Rory J.;
Pearson, Ewan R.;
Langston, Rosamund;
Sutherland, Calum

Publication type:

Article

Different mechanisms are used by insulin to repress three genes that contain a homologous thymine-rich insulin response element

Published in:

FEBS Letters, 2003, v. 549, n. 1-3, p. 72, doi. 10.1016/S0014-5793(03)00774-9

By:

Patel, Satish;
Lipina, Christopher;
Sutherland, Calum

Publication type:

Article

Zhou et al. reply.

Published in:

2012

By:

Zhou, Kaixin;
Bellenguez, Celine;
Sutherland, Calum;
Hardie, Grahame;
Palmer, Colin;
Donnelly, Peter;
Pearson, Ewan

Publication type:

Letter

Hypertension fails to disrupt white matter integrity in young or aged Fisher (F44) Cyp1a1Ren2 transgenic rats.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2015, v. 35, n. 2, p. 188, doi. 10.1038/jcbfm.2014.201

By:

Holland, Philip R;
Pannozzo, Mercede A;
Bastin, Mark E;
McNeilly, Allison D;
Ferguson, Karen J;
Caughey, Sarah;
Jansen, Maurits A;
Merrifield, Gavin D;
Marshall, Ian;
Mullins, John J;
Wardlaw, Joanna M;
Sutherland, Calum;
Horsburgh, Karen

Publication type:

Article

Phosphorylation of a splice variant of collapsin response mediator protein 2 in the nucleus of tumour cells links cyclin dependent kinase-5 to oncogenesis.

Published in:

2015

By:

Grant, Nicola J.;
Coates, Philip J.;
Woods, Yvonne L.;
Bray, Susan E.;
Morrice, Nicholas A.;
Hastie, C. James;
Lamont, Douglas J.;
Carey, Francis A.;
Sutherland, Calum

Publication type:

journal article

Mutation of the PDK1 PH Domain Inhibits Protein Kinase B/Akt, Leading to Small Size and Insulin Resistance.

Published in:

Molecular & Cellular Biology, 2008, v. 28, n. 10, p. 15, doi. 10.1128/MCB.02032-07

By:

Bayascas, Jose R.;
Wullschleger, Stephan;
Sakamoto, Kei;
García-Martínez, Juan M.;
Clacher, Carol;
Komander, David;
Van Aalten, Daan M. F.;
Boini, Krishna M.;
Lang, Florian;
Lipina, Christopher;
Logie, Lisa;
Sutherland, Calum;
Chudek, John A.;
Van Diepen, Janna A.;
Voshol, Peter J.;
Lucocq, John M.;
Alessi, Dario R.

Publication type:

Article

Implementation of point-of-care HbA1C instruments into community pharmacies: Initial development of a pathway for robust community testing.

Published in:

Annals of Clinical Biochemistry, 2024, v. 61, n. 4, p. 273, doi. 10.1177/00045632231219380

By:

Radley, Andrew;
Beer, Lewis;
Rushdi, Danya;
Close, Hazel;
McBurney, Stephen;
Mackenzie, Adrian;
Gourlay, Anna;
Barnett, Anna;
Grant, Alison;
Greig, Neil;
Dow, Ellie;
Sutherland, Calum

Publication type:

Article

Characterization of a Protein Kinase B Inhibitor In Vitro and in Insulin-Treated Liver Cells.

Published in:

Diabetes, 2007, v. 56, n. 9, p. 2218, doi. 10.2337/db07-0343

By:

Logie, Lisa;
Ruiz-Alcaraz, Antonio J.;
Keane, Michael;
Woods, Yvonne L.;
Bain, Jennifer;
Marquez, Rudolfo;
Alessi, Dario R.;
Sutherland, Calum

Publication type:

Article

5-Aminoimidazole-4-Carboxamide 1-β-D-Ribofuranoside Acutely Stimulates Skeletal Muscle 2-Deoxyglucose Uptake in Healthy Men.

Published in:

Diabetes, 2007, v. 56, n. 8, p. 2078, doi. 10.2337/db06-1716

By:

Cuthbertson, Daniel J.;
Babraj, John A.;
Mustard, Kirsteen J. W.;
Towler, Mhairi C.;
Green, Kevin A.;
Wackerhage, Henning;
Leese, Graeme P.;
Baar, Keith;
Thomason-Hughes, Michaela;
Sutherland, Calum;
Hardie, D. Grahame;
Rennie, Michael J.

Publication type:

Article

Aicar Acutely Stimulates Deoxyglucose Uptake in Men with Type 2 Diabetes.

Published in:

Diabetes, 2007, v. 56, p. A401

By:

Cuthbertson, Daniel;
Babraj, John A.;
Sutherland, Calum;
Rennie, Michael J.

Publication type:

Article

Aicar Acutely Stimulates Skeletal Muscle Deoxyglucose Uptake in Healthy Men.

Published in:

Diabetes, 2007, v. 56, p. A400

By:

Babraj, John A.;
Sutherland, Calum;
Hardie, Gramme;
Rennie, Michael J.;
Cuthbertson, Daniel J.

Publication type:

Article

Inhibition of GSK-3 selectively reduces glucose-6-phosphatase and phosphatase and phosphoenolypyruvate carboxykinase gene expression.

Published in:

2001

By:

Lochhead, Pamela A.;
Coghlan, Matthew;
Rice, Simon Q.J.;
Sutherland, Calum;
Lochhead, P A;
Coghlan, M;
Rice, S Q;
Sutherland, C

Publication type:

journal article

5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase.

Published in:

2000

By:

Lochhead, Pamela A.;
Salt, Ian P.;
Walker, Kay S.;
Hardie, D. Grahame;
Sutherland, Calum;
Lochhead, P A;
Salt, I P;
Walker, K S;
Hardie, D G;
Sutherland, C

Publication type:

journal article

Oxidative and chemical stress mimic insulin by selectively inhibiting the expression of phosphoenolpyruvate carboxykinase in hepatoma cells.

Published in:

1997

By:

Sutherland, Calum;
Tebbey, Paul W.;
Granner, Daryl K.;
Sutherland, C;
Tebbey, P W;
Granner, D K

Publication type:

journal article

Evidence that glycogen synthase kinase-3 isoforms have distinct substrate preference in the brain M. P. M. Soutar et al. GSK3 isoforms phosphorylate substrates differentially.

Published in:

Journal of Neurochemistry, 2010, v. 115, n. 4, p. 974, doi. 10.1111/j.1471-4159.2010.06988.x

By:

Soutar, Marc P. M.;
Woo-Yang Kim;
Williamson, Ritchie;
Peggie, Mark;
Hastie, Charles James;
McLauchlan, Hilary;
Snider, William D.;
Gordon-Weeks, Phillip R.;
Sutherland, Calum

Publication type:

Article

Collapsin response mediator protein-2 hyperphosphorylation is an early event in Alzheimer’s disease progression.

Published in:

Journal of Neurochemistry, 2007, v. 103, n. 3, p. 1132, doi. 10.1111/j.1471-4159.2007.04829.x

By:

Cole, Adam R.;
Noble, Wendy;
Aalten, Lidy van;
Plattner, Florian;
Meimaridou, Rena;
Hogan, Dale;
Taylor, Margaret;
LaFrancois, John;
Gunn-Moore, Frank;
Verkhratsky, Alex;
Oddo, Salvatore;
LaFerla, Frank;
Giese, K. Peter;
Dineley, Kelly T.;
Duff, Karen;
Richardson, Jill C.;
Shi Du Yan;
Hanger, Diane P.;
Allan, Stuart M.;
Sutherland, Calum

Publication type:

Article

The aminoguanidine carboxylate BVT.12777 activates ATP-sensitive K<sup>+</sup> channels in the rat insulinoma cell line, CRI-G1.

Published in:

BMC Pharmacology, 2004, v. 4, p. 1, doi. 10.1186/1471-2210-4-17

By:

Kinsella, Jackie M.;
Laidlaw, Hilary A.;
Tang, Teresa;
Harvey, Jenni;
Sutherland, Calum;
Ashford, Michael L. J.

Publication type:

Article