Works by Suthar, Mehul S.

Results: 39

A wild boar cathelicidin peptide derivative inhibits severe acute respiratory syndrome coronavirus-2 and its drifted variants.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-41850-7

By:

von Beck, Troy;
Navarrete, Karla;
Arce, Nicholas A.;
Gao, Mu;
Dale, Gordon A.;
Davis-Gardner, Meredith E.;
Floyd, Katharine;
Mena Hernandez, Luis;
Mullick, Nikita;
Vanderheiden, Abigail;
Skountzou, Ioanna;
Kuchipudi, Suresh V.;
Saravanan, Rathi;
Li, Renhao;
Skolnick, Jeffrey;
Suthar, Mehul S.;
Jacob, Joshy

Publication type:

Article

A wild boar cathelicidin peptide derivative inhibits severe acute respiratory syndrome coronavirus-2 and its drifted variants.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-41850-7

By:

von Beck, Troy;
Navarrete, Karla;
Arce, Nicholas A.;
Gao, Mu;
Dale, Gordon A.;
Davis-Gardner, Meredith E.;
Floyd, Katharine;
Mena Hernandez, Luis;
Mullick, Nikita;
Vanderheiden, Abigail;
Skountzou, Ioanna;
Kuchipudi, Suresh V.;
Saravanan, Rathi;
Li, Renhao;
Skolnick, Jeffrey;
Suthar, Mehul S.;
Jacob, Joshy

Publication type:

Article

Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses.

Published in:

Cellular Microbiology, 2009, v. 11, n. 6, p. 880, doi. 10.1111/j.1462-5822.2009.01311.x

By:

Suthar, Mehul S.;
Gale Jr., Michael;
Owen, David M.

Publication type:

Article

Humoral Immune Responses Against Zika Virus Infection and the Importance of Preexisting Flavivirus Immunity.

Published in:

2017

By:

Priyamvada, Lalita;
Suthar, Mehul S.;
Ahmed, Rafi;
Wrammert, Jens

Publication type:

journal article

Timing of exposure is critical in a highly sensitive model of SARS-CoV-2 transmission.

Published in:

PLoS Pathogens, 2022, v. 18, n. 3, p. 1, doi. 10.1371/journal.ppat.1010181

By:

Ganti, Ketaki;
Ferreri, Lucas M.;
Lee, Chung-Young;
Bair, Camden R.;
Delima, Gabrielle K.;
Holmes, Kate E.;
Suthar, Mehul S.;
Lowen, Anice C.

Publication type:

Article

West Nile virus infection and immunity.

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 2, p. 115, doi. 10.1038/nrmicro2950

By:

Suthar, Mehul S.;
Diamond, Michael S.;
Gale Jr, Michael

Publication type:

Article

SARS-CoV-2 Viral Shedding and Rapid Antigen Test Performance -- Respiratory Virus Transmission Network, November 2022--May 2023.

Published in:

MMWR: Morbidity & Mortality Weekly Report, 2024, v. 73, n. 16, p. 365, doi. 10.15585/mmwr.mm7316a2

By:

Smith-Jeffcoat, Sarah E.;
Mellis, Alexandra M.;
Grijalva, Carlos G.;
Talbot, H. Keipp;
Schmitz, Jonathan;
Lutrick, Karen;
Ellingson, Katherine D.;
Stockwell, Melissa S.;
McLaren, Son H.;
Nguyen, Huong Q.;
Rao, Suchitra;
Asturias, Edwin J.;
Davis-Gardner, Meredith E.;
Suthar, Mehul S.;
Kirking, Hannah L.

Publication type:

Article

The amphibian peptide Yodha is virucidal for Zika and dengue viruses.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-80596-4

By:

Lee, Song Hee;
Kim, Eui Ho;
O'neal, Justin T.;
Dale, Gordon;
Holthausen, David J.;
Bowen, James R.;
Quicke, Kendra M.;
Skountzou, Ioanna;
Gopal, Shyla;
George, Sanil;
Wrammert, Jens;
Suthar, Mehul S.;
Jacob, Joshy

Publication type:

Article

Interferon‐induced transmembrane protein 3 (IFITM3) limits lethality of SARS‐CoV‐2 in mice.

Published in:

EMBO Reports, 2023, v. 24, n. 4, p. 1, doi. 10.15252/embr.202256660

By:

Kenney, Adam D;
Zani, Ashley;
Kawahara, Jeffrey;
Eddy, Adrian C;
Wang, Xiao‐Liang;
Mahesh, KC;
Lu, Mijia;
Thomas, Jeronay;
Kohlmeier, Jacob E;
Suthar, Mehul S;
Hemann, Emily A;
Li, Jianrong;
Peeples, Mark E;
Hall‐Stoodley, Luanne;
Forero, Adriana;
Cai, Chuanxi;
Ma, Jianjie;
Yount, Jacob S

Publication type:

Article

Dendritic cell-associated MAVS is required to control West Nile virus replication and ensuing humoral immune responses.

Published in:

PLoS ONE, 2019, v. 14, n. 6, p. 1, doi. 10.1371/journal.pone.0218928

By:

Roe, Kelsey;
Giordano, Daniela;
Young, Lucy B.;
Draves, Kevin E.;
Holder, Ursula;
Suthar, Mehul S.;
Jr.Gale, Michael;
Clark, Edward A.

Publication type:

Article

An inactivated NDV-HXP-S COVID-19 vaccine elicits a higher proportion of neutralizing antibodies in humans than mRNA vaccination.

Published in:

Science Translational Medicine, 2023, v. 15, n. 683, p. 1, doi. 10.1126/scitranslmed.abo2847

By:

Carreño, Juan Manuel;
Raskin, Ariel;
Singh, Gagandeep;
Tcheou, Johnstone;
Kawabata, Hisaaki;
Gleason, Charles;
Srivastava, Komal;
Vigdorovich, Vladimir;
Dambrauskas, Nicholas;
Gupta, Sneh Lata;
González Domínguez, Irene;
Martinez, Jose Luis;
Slamanig, Stefan;
Sather, D. Noah;
Raghunandan, Rama;
Wirachwong, Ponthip;
Muangnoicharoen, Sant;
Pitisuttithum, Punnee;
Wrammert, Jens;
Suthar, Mehul S.

Publication type:

Article

Strong T<sub>H</sub>1-biased CD4 T cell responses are associated with diminished SIV vaccine efficacy.

Published in:

Science Translational Medicine, 2019, v. 11, n. 519, p. 1, doi. 10.1126/scitranslmed.aav1800

By:

Chamcha, Venkateswarlu;
Reddy, Pradeep B. J.;
Kannanganat, Sunil;
Wilkins, Courtney;
Gangadhara, Sailaja;
Velu, Vijayakumar;
Green, Richard;
Law, G. Lynn;
Chang, Jean;
Bowen, James R.;
Kozlowski, Pamela A.;
Lifton, Michelle;
Santra, Sampa;
Legere, Traci;
Chea, Lynette S.;
Chennareddi, Lakshmi;
Yu, Tianwei;
Suthar, Mehul S.;
Silvestri, Guido;
Derdeyn, Cynthia A.

Publication type:

Article

AS03 adjuvant enhances the magnitude, persistence, and clonal breadth of memory B cell responses to a plant-based COVID-19 vaccine in humans.

Published in:

Science Immunology, 2024, v. 9, n. 94, p. 1, doi. 10.1126/sciimmunol.adi8039

By:

Grigoryan, Lilit;
Feng, Yupeng;
Bellusci, Lorenza;
Lai, Lilin;
Wali, Bushra;
Ellis, Madison;
Yuan, Meng;
Arunachalam, Prabhu S.;
Hu, Mengyun;
Kowli, Sangeeta;
Gupta, Sheena;
Maysel-Auslender, Sofia;
Maecker, Holden T.;
Samaha, Hady;
Rouphael, Nadine;
Wilson, Ian A.;
Moreno, Alberto C.;
Suthar, Mehul S.;
Khurana, Surender;
Pillet, Stéphane

Publication type:

Article

Measure and Countermeasure: Type I IFN (IFN-α/β) Antiviral Response against West Nile Virus.

Published in:

Journal of Innate Immunity, 2009, v. 1, n. 5, p. 435, doi. 10.1159/000226248

By:

Daffis, Stephane;
Suthar, Mehul S.;
Gale, Jr., Michael;
Diamond, Michael S.

Publication type:

Article

Immune responses and therapeutic challenges in paediatric patients with new‐onset acute myeloid leukaemia and concomitant COVID‐19.

Published in:

British Journal of Haematology, 2021, v. 194, n. 3, p. 549, doi. 10.1111/bjh.17517

By:

Patel, Pratik A.;
Lapp, Stacey A.;
Grubbs, Gabrielle;
Edara, Venkata V.;
Rostad, Christina A.;
Stokes, Claire L.;
Pauly, Melinda G.;
Anderson, Evan J.;
Piantadosi, Anne;
Suthar, Mehul S.;
Khurana, Surender;
Sabnis, Himalee S.

Publication type:

Article

The Innate Immune Playbook for Restricting West Nile Virus Infection.

Published in:

Viruses (1999-4915), 2013, v. 5, n. 11, p. 2643, doi. 10.3390/v5112643

By:

Quicke, Kendra M.;
Suthar, Mehul S.

Publication type:

Article

Original antigenic sin responses to Betacoronavirus spike proteins are observed in a mouse model, but are not apparent in children following SARS-CoV-2 infection.

Published in:

PLoS ONE, 2021, v. 16, n. 8, p. 1, doi. 10.1371/journal.pone.0256482

By:

Lapp, Stacey A.;
Edara, Venkata Viswanadh;
Lu, Austin;
Lai, Lilin;
Hussaini, Laila;
Chahroudi, Ann;
Anderson, Larry J.;
Suthar, Mehul S.;
Anderson, Evan J.;
Rostad, Christina A.

Publication type:

Article

Rapid Detection and Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Omicron Variant in a Returning Traveler.

Published in:

Clinical Infectious Diseases, 2022, v. 75, n. 1, p. e350, doi. 10.1093/cid/ciac032

By:

Sexton, Mary Elizabeth;
Waggoner, Jesse J;
Carmola, Ludy R;
Nguyen, Phuong Vi;
Wang, Ethan;
Khosravi, Dara;
Taz, Azmain;
Arthur, Robert A;
Patel, Mit;
Edara, Venkata Viswanadh;
Foster, Stephanie L;
Moore, Kathryn M;
Gagne, Matthew;
Roberts-Torres, Jesmine;
Henry, Amy R;
Godbole, Sucheta;
Douek, Daniel C;
Rouphael, Nadine;
Suthar, Mehul S;
Piantadosi, Anne

Publication type:

Article

Deficient IFN Signaling by Myeloid Cells Leads to MAVS-Dependent Virus-Induced Sepsis.

Published in:

PLoS Pathogens, 2014, v. 10, n. 4, p. 1, doi. 10.1371/journal.ppat.1004086

By:

Pinto, Amelia K.;
Ramos, Hilario J.;
Wu, Xiaobo;
Aggarwal, Shilpa;
Shrestha, Bimmi;
Gorman, Matthew;
Kim, Kristin Y.;
Suthar, Mehul S.;
Atkinson, John P.;
Gale Jr, Michael;
Diamond, Michael S.

Publication type:

Article

Innate Immune Sensing of Flaviviruses.

Published in:

PLoS Pathogens, 2013, v. 9, n. 9, p. 1, doi. 10.1371/journal.ppat.1003541

By:

Suthar, Mehul S.;
Aguirre, Sebastian;
Fernandez-Sesma, Ana

Publication type:

Article

A Systems Biology Approach Reveals that Tissue Tropism to West Nile Virus Is Regulated by Antiviral Genes and Innate Immune Cellular Processes.

Published in:

PLoS Pathogens, 2013, v. 9, n. 2, p. 1, doi. 10.1371/journal.ppat.1003168

By:

Suthar, Mehul S.;
Brassil, Margaret M.;
Blahnik, Gabriele;
McMillan, Aimee;
Ramos, Hilario J.;
Proll, Sean C.;
Belisle, Sarah E.;
Katze, Michael G.;
Gale Jr., Michael

Publication type:

Article

IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling.

Published in:

PLoS Pathogens, 2013, v. 9, n. 1, p. 1, doi. 10.1371/journal.ppat.1003118

By:

Lazear, Helen M.;
Lancaster, Alissa;
Wilkins, Courtney;
Suthar, Mehul S.;
Huang, Albert;
Vick, Sarah C.;
Clepper, Lisa;
Thackray, Larissa;
Brassil, Margaret M.;
Virgin, Herbert W.;
Nikolich-Zugich, Janko;
Moses, Ashlee V.;
Gale, Jr., Michael;
Früh, Klaus;
Diamond, Michael S.

Publication type:

Article

IL-1β Signaling Promotes CNS-Intrinsic Immune Control of West Nile Virus Infection.

Published in:

PLoS Pathogens, 2012, v. 8, n. 11, p. 1, doi. 10.1371/journal.ppat.1003039

By:

Ramos, Hilario J.;
Lanteri, Marion C.;
Blahnik, Gabriele;
Negash, Amina;
Suthar, Mehul S.;
Brassil, Margaret M.;
Sodhi, Khushbu;
Treuting, Piper M.;
Busch, Michael P.;
Norris, Philip J.;
Gale Jr., Michael

Publication type:

Article

Interferon Regulatory Factor-1 (IRF-1) Shapes Both Innate and CD8<sup>+</sup> T Cell Immune Responses against West Nile Virus Infection.

Published in:

PLoS Pathogens, 2011, v. 7, n. 9, p. 1, doi. 10.1371/journal.ppat.1002230

By:

Brien, James D.;
Daffis, Stephane;
Lazear, Helen M.;
Cho, Hyelim;
Suthar, Mehul S.;
Gale Jr., Michael;
Diamond, Michael S.

Publication type:

Article

Rabies Virus Infection Induces Type I Interferon Production in an IPS-1 Dependent Manner While Dendritic Cell Activation Relies on IFNAR Signaling.

Published in:

PLoS Pathogens, 2010, v. 6, n. 7, p. 1, doi. 10.1371/journal.ppat.1001016

By:

Faul, Elizabeth J.;
Wanjalla, Celestine N.;
Suthar, Mehul S.;
Gale Jr., Michael;
Wirblich, Christoph;
Schnell, Matthias J.

Publication type:

Article

IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity.

Published in:

PLoS Pathogens, 2010, v. 6, n. 2, p. 1, doi. 10.1371/journal.ppat.1000757

By:

Suthar, Mehul S.;
Ma, Daphne Y.;
Thomas, Sunil;
Lund, Jennifer M.;
Nu Zhang;
Daffis, Stephane;
Rudensky, Alexander Y.;
Bevan, Michael J.;
Clark, Edward A.;
Kaja, Murali-Krishna;
Diamond, Michael S.;
Gale Jr., Michael

Publication type:

Article

Induction of IFN-β and the Innate Antiviral Response in Myeloid Cells Occurs through an IPS-1-Dependent Signal That Does Not Require IRF-3 and IRF-7.

Published in:

PLoS Pathogens, 2009, v. 5, n. 10, p. 1, doi. 10.1371/journal.ppat.1000607

By:

Daffis, Stephane;
Suthar, Mehul S.;
Szretter, Kristy J.;
Gale Jr., Michael;
Diamond, Michael S.

Publication type:

Article

SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19808-4

By:

Zhang, Lizhou;
Jackson, Cody B.;
Mou, Huihui;
Ojha, Amrita;
Peng, Haiyong;
Quinlan, Brian D.;
Rangarajan, Erumbi S.;
Pan, Andi;
Vanderheiden, Abigail;
Suthar, Mehul S.;
Li, Wenhui;
Izard, Tina;
Rader, Christoph;
Farzan, Michael;
Choe, Hyeryun

Publication type:

Article

Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-19231-9

By:

Hurlburt, Nicholas K.;
Seydoux, Emilie;
Wan, Yu-Hsin;
Edara, Venkata Viswanadh;
Stuart, Andrew B.;
Feng, Junli;
Suthar, Mehul S.;
McGuire, Andrew T.;
Stamatatos, Leonidas;
Pancera, Marie

Publication type:

Article

Long-term alterations in brain and behavior after postnatal Zika virus infection in infant macaques.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16320-7

By:

Raper, Jessica;
Kovacs-Balint, Zsofia;
Mavigner, Maud;
Gumber, Sanjeev;
Burke, Mark W.;
Habib, Jakob;
Mattingly, Cameron;
Fair, Damien;
Earl, Eric;
Feczko, Eric;
Styner, Martin;
Jean, Sherrie M.;
Cohen, Joyce K.;
Suthar, Mehul S.;
Sanchez, Mar M.;
Alvarado, Maria C.;
Chahroudi, Ann

Publication type:

Article

Atovaquone and Pibrentasvir Inhibit the SARS-CoV-2 Endoribonuclease and Restrict Infection In Vitro but Not In Vivo.

Published in:

Viruses (1999-4915), 2023, v. 15, n. 9, p. 1841, doi. 10.3390/v15091841

By:

von Beck, Troy;
Mena Hernandez, Luis;
Zhou, Hongyi;
Floyd, Katharine;
Suthar, Mehul S.;
Skolnick, Jeffrey;
Jacob, Joshy

Publication type:

Article

Pre-Existing Dengue Immunity Drives a DENV-Biased Plasmablast Response in ZIKV-Infected Patient.

Published in:

Viruses (1999-4915), 2019, v. 11, n. 1, p. 19, doi. 10.3390/v11010019

By:

Bhaumik, Siddhartha K.;
Priyamvada, Lalita;
Kauffman, Robert C.;
Lai, Lilin;
Natrajan, Muktha S.;
Cho, Alice;
Rouphael, Nadine;
Suthar, Mehul S.;
Mulligan, Mark J.;
Wrammert, Jens

Publication type:

Article

Neutralizing Antibodies Against SARS-CoV-2 Variants After Infection and Vaccination.

Published in:

2021

By:

Edara, Venkata Viswanadh;
Hudson, William H.;
Xie, Xuping;
Ahmed, Rafi;
Suthar, Mehul S.

Publication type:

journal article

Divergence of variant antibodies following SARS-CoV-2 booster vaccines in myeloma and impact of hybrid immunity.

Published in:

NPJ Vaccines, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41541-024-00999-6

By:

Moreno, Alberto;
Manning, Kelly;
Azeem, Maryam I.;
Nooka, Ajay K.;
Ellis, Madison;
Manalo, Renee Julia;
Switchenko, Jeffrey M.;
Wali, Bushra;
Kaufman, Jonathan L.;
Hofmeister, Craig C.;
Joseph, Nisha S.;
Lonial, Sagar;
Dhodapkar, Kavita M.;
Dhodapkar, Madhav V.;
Suthar, Mehul S.

Publication type:

Article

Influenza Virus-like Particle-Based Hybrid Vaccine Containing RBD Induces Immunity against Influenza and SARS-CoV-2 Viruses.

Published in:

Vaccines, 2022, v. 10, n. 6, p. N.PAG, doi. 10.3390/vaccines10060944

By:

Bommireddy, Ramireddy;
Stone, Shannon;
Bhatnagar, Noopur;
Kumari, Pratima;
Munoz, Luis E.;
Oh, Judy;
Kim, Ki-Hye;
Berry, Jameson T. L.;
Jacobsen, Kristen M.;
Jaafar, Lahcen;
Naing, Swe-Htet;
Blackerby, Allison N.;
Gaag, Tori Van der;
Wright, Chloe N.;
Lai, Lilin;
Pack, Christopher D.;
Ramachandiran, Sampath;
Suthar, Mehul S.;
Kang, Sang-Moo;
Kumar, Mukesh

Publication type:

Article

Zika Virus Antagonizes Type I Interferon Responses during Infection of Human Dendritic Cells.

Published in:

PLoS Pathogens, 2017, v. 13, n. 2, p. 1, doi. 10.1371/journal.ppat.1006164

By:

Bowen, James R.;
Quicke, Kendra M.;
Maddur, Mohan S.;
O’Neal, Justin T.;
McDonald, Circe E.;
Fedorova, Nadia B.;
Puri, Vinita;
Shabman, Reed S.;
Pulendran, Bali;
Suthar, Mehul S.

Publication type:

Article

Mouse-adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge.

Published in:

PLoS Biology, 2021, v. 19, n. 11, p. 1, doi. 10.1371/journal.pbio.3001284

By:

Muruato, Antonio;
Vu, Michelle N.;
Johnson, Bryan A.;
Davis-Gardner, Meredith E.;
Vanderheiden, Abigail;
Lokugamage, Kumari;
Schindewolf, Craig;
Crocquet-Valdes, Patricia A.;
Langsjoen, Rose M.;
Plante, Jessica A.;
Plante, Kenneth S.;
Weaver, Scott C.;
Debbink, Kari;
Routh, Andrew L.;
Walker, David;
Suthar, Mehul S.;
Shi, Pei-Yong;
Xie, Xuping;
Menachery, Vineet D.

Publication type:

Article

Negative regulators of the RIG-I-like receptor signaling pathway.

Published in:

European Journal of Immunology, 2017, v. 47, n. 4, p. 615, doi. 10.1002/eji.201646484

By:

Quicke, Kendra M.;
Diamond, Michael S.;
Suthar, Mehul S.

Publication type:

Article

Mechanisms by which the cystic fibrosis transmembrane conductance regulator may influence SARS‐CoV‐2 infection and COVID‐19 disease severity.

Published in:

FASEB Journal, 2023, v. 37, n. 11, p. 1, doi. 10.1096/fj.202300077R

By:

Tedbury, Philip R.;
Manfredi, Candela;
Degenhardt, Frauke;
Conway, Joseph;
Horwath, Michael C.;
McCracken, Courtney;
Sorscher, Adam J.;
Moreau, Sandy;
Wright, Christine;
Edwards, Carolina;
Brewer, Jo;
Guarner, Jeannette;
de Wit, Emmie;
Williamson, Brandi N.;
Suthar, Mehul S.;
Ong, Yee T.;
Roback, John D.;
Alter, David N.;
Holter, Jan C.;
Karlsen, Tom H.

Publication type:

Article