Works matching AU Suter, Laura

Results: 31

Current Challenges and Controversies in Drug-Induced Liver Injury.

Published in:

Drug Safety, 2012, v. 35, n. 12, p. 1099, doi. 10.2165/11632970-000000000-00000

By:

Corsini, Alberto;
Ganey, Patricia;
Ju, Cynthia;
Kaplowitz, Neil;
Pessayre, Dominique;
Roth, Robert;
Watkins, Paul B.;
Albassam, Mudher;
Liu, Baolian;
Stancic, Saray;
Suter, Laura;
Bortolini, Michele

Publication type:

Article

In vitro to in vivo extrapolation and high-content imaging for simultaneous characterization of chemically induced liver steatosis and markers of hepatotoxicity.

Published in:

Archives of Toxicology, 2023, v. 97, n. 6, p. 1701, doi. 10.1007/s00204-023-03490-8

By:

Müller, Fabrice A.;
Stamou, Marianna;
Englert, Felix H.;
Frenzel, Ole;
Diedrich, Sabine;
Suter-Dick, Laura;
Wambaugh, John F.;
Sturla, Shana J.

Publication type:

Article

Novel Strategy to Assess the Neurotoxicity of Organic Solvents Such as Glycol Ethers: Protocol for Combining In Vitro and In Silico Methods With Human-Controlled Exposure Experiments.

Published in:

JMIR Research Protocols, 2024, v. 13, p. 1, doi. 10.2196/50300

By:

Hopf, Nancy B;
Suter-Dick, Laura;
Huwyler, Jörg;
Borgatta, Myriam;
Hegg, Lucie;
Pamies, David;
Paschoud, Hélène;
Puligilla, Ramya Deepthi;
Reale, Elena;
Werner, Sophie;
Zurich, Marie-Gabrielle

Publication type:

Article

Apical Medium Flow Influences the Morphology and Physiology of Human Proximal Tubular Cells in a Microphysiological System.

Published in:

Bioengineering (Basel), 2022, v. 9, n. 10, p. N.PAG, doi. 10.3390/bioengineering9100516

By:

Specioso, Gabriele;
Bovard, David;
Zanetti, Filippo;
Maranzano, Fabio;
Merg, Céline;
Sandoz, Antonin;
Titz, Bjoern;
Dalcanale, Federico;
Hoeng, Julia;
Renggli, Kasper;
Suter-Dick, Laura

Publication type:

Article

In Vitro Hepatic Metabolism Input Parameters Support Toxicokinetic Simulations for the Formation of Methoxy Propionic Acid From β‐Isomer Propylene Glycol Methyl Ether.

Published in:

Pharmacology Research & Perspectives, 2024, v. 12, n. 6, p. 1, doi. 10.1002/prp2.70037

By:

Werner, Sophie;
Hegg, Lucie;
Hopf, Nancy B.;
Borgatta, Myriam;
Suter‐Dick, Laura

Publication type:

Article

Methotrexate-Induced Liver Injury Is Associated with Oxidative Stress, Impaired Mitochondrial Respiration, and Endoplasmic Reticulum Stress In Vitro.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 23, p. 15116, doi. 10.3390/ijms232315116

By:

Schmidt, Saskia;
Messner, Catherine Jane;
Gaiser, Carine;
Hämmerli, Carina;
Suter-Dick, Laura

Publication type:

Article

Directional Submicrofiber Hydrogel Composite Scaffolds Supporting Neuron Differentiation and Enabling Neurite Alignment.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 19, p. 11525, doi. 10.3390/ijms231911525

By:

Mungenast, Lena;
Züger, Fabian;
Selvi, Jasmin;
Faia-Torres, Ana Bela;
Rühe, Jürgen;
Suter-Dick, Laura;
Gullo, Maurizio R.

Publication type:

Article

Identification of miR-199a-5p, miR-214-3p and miR-99b-5p as Fibrosis-Specific Extracellular Biomarkers and Promoters of HSC Activation.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 18, p. 9799, doi. 10.3390/ijms22189799

By:

Messner, Catherine Jane;
Schmidt, Saskia;
Özkul, Dilek;
Gaiser, Carine;
Terracciano, Luigi;
Krähenbühl, Stephan;
Suter-Dick, Laura

Publication type:

Article

Single Cell Gene Expression Analysis in a 3D Microtissue Liver Model Reveals Cell Type-Specific Responses to Pro-Fibrotic TGF-β1 Stimulation.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4372, doi. 10.3390/ijms22094372

By:

Messner, Catherine Jane;
Babrak, Lmar;
Titolo, Gaia;
Caj, Michaela;
Miho, Enkelejda;
Suter-Dick, Laura;
Ramadori, Giuliano;
Marin, Jose J.G.

Publication type:

Article

3D printed microfluidic modules: passive mixers and cells encapsulation in alginate.

Published in:

Current Directions in Biomedical Engineering, 2022, v. 8, n. 2, p. 27, doi. 10.1515/cdbme-2022-1008

By:

Dalcanale, Federico;
Caj, Michaela;
Schuler, Felix;
Ganeshanathan, Kireedan;
Suter-Dick, Laura

Publication type:

Article

Screening of Drug-Transporter Interactions in a 3D Microfluidic Renal Proximal Tubule on a Chip.

Published in:

AAPS Journal, 2018, v. 20, n. 5, p. 1, doi. 10.1208/s12248-018-0247-0

By:

Vriend, Jelle;
Nieskens, Tom T. G.;
Vormann, Marianne K.;
van den Berge, Bartholomeus T.;
van den Heuvel, Angelique;
Russel, Frans G. M.;
Suter-Dick, Laura;
Lanz, Henriëtte L.;
Vulto, Paul;
Masereeuw, Rosalinde;
Wilmer, Martijn J.

Publication type:

Article

Combining Extracellular miRNA Determination with Microfluidic 3D Cell Cultures for the Assessment of Nephrotoxicity: a Proof of Concept Study.

Published in:

AAPS Journal, 2018, v. 20, n. 5, p. 1, doi. 10.1208/s12248-018-0245-2

By:

Suter-Dick, Laura;
Mauch, L.;
Ramp, D.;
Caj, M.;
Vormann, M. K.;
Hutter, S.;
Lanz, H. L.;
Vriend, J.;
Masereeuw, R.;
Wilmer, M. J.

Publication type:

Article

Nephrotoxicity and Kidney Transport Assessment on 3D Perfused Proximal Tubules.

Published in:

AAPS Journal, 2018, v. 20, n. 5, p. 1, doi. 10.1208/s12248-018-0248-z

By:

Vormann, Marianne K.;
Gijzen, Linda;
Hutter, Simon;
Boot, Lisette;
Nicolas, Arnaud;
van den Heuvel, Angelique;
Vriend, Jelle;
Chee Ping Ng;
Nieskens, Tom T. G.;
van Duinen, Vincent;
de Wagenaar, Bjorn;
Masereeuw, Rosalinde;
Suter-Dick, Laura;
Trietsch, Sebastiaan J.;
Wilmer, Martijn;
Joore, Jos;
Vulto, Paul;
Lanz, Henriette L.

Publication type:

Article

Pro-fibrotic compounds induce stellate cell activation, ECM-remodelling and Nrf2 activation in a human 3D-multicellular model of liver fibrosis.

Published in:

PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0179995

By:

Prestigiacomo, Vincenzo;
Weston, Anna;
Messner, Simon;
Lampart, Franziska;
Suter-Dick, Laura

Publication type:

Article

Key Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation Plans.

Published in:

BioMed Research International, 2016, v. 2016, p. 1, doi. 10.1155/2016/9737920

By:

Atienzar, Franck A.;
Blomme, Eric A.;
Chen, Minjun;
Hewitt, Philip;
Kenna, J. Gerry;
Labbe, Gilles;
Moulin, Frederic;
Pognan, Francois;
Roth, Adrian B.;
Suter-Dick, Laura;
Ukairo, Okechukwu;
Weaver, Richard J.;
Will, Yvonne;
Dambach, Donna M.

Publication type:

Article

A Real-time Impedance-Based Screening Assay for Drug-Induced Vascular Leakage.

Published in:

Toxicological Sciences, 2014, v. 138, n. 2, p. 333, doi. 10.1093/toxsci/kft336

By:

Kustermann, Stefan;
Manigold, Tobias;
Ploix, Corinne;
Skubatz, Marion;
Heckel, Tobias;
Hinton, Heather;
Weiser, Thomas;
Singer, Thomas;
Suter, Laura;
Roth, Adrian

Publication type:

Article

Primary Endothelial Damage Is the Mechanism of Cardiotoxicity of Tubulin-Binding Drugs.

Published in:

Toxicological Sciences, 2010, v. 117, n. 1, p. 144, doi. 10.1093/toxsci/kfq189

By:

Mikaelian, Igor;
Buness, Andreas;
de Vera-Mudry, Maria-Cristina;
Kanwal, Charu;
Coluccio, Denise;
Rasmussen, Erik;
Char, Hing W.;
Carvajal, Valerie;
Hilton, Holly;
Funk, Juergen;
Hoflack, Jean-Christophe;
Fielden, Mark;
Herting, Frank;
Dunn, Michael;
Suter-Dick, Laura

Publication type:

Article

Gene Expression in Two Hepatic Cell Lines, Cultured Primary Hepatocytes, and Liver Slices Compared to the in Vivo Liver Gene Expression in Rats: Possible Implications for Toxicogenomics Use of in Vitro Systems.

Published in:

Toxicological Sciences, 2003, v. 73, n. 2, p. 386, doi. 10.1093/toxsci/kfg064

By:

Boess, Franziska;
Kamber, Markus;
Romer, Simona;
Gasser, Rodolfo;
Muller, Dieter;
Albertini, Silvio;
Suter, Laura

Publication type:

Article

Nrf2 protects stellate cells from Smad-dependent cell activation.

Published in:

PLoS ONE, 2018, v. 13, n. 7, p. 1, doi. 10.1371/journal.pone.0201044

By:

Prestigiacomo, Vincenzo;
Suter-Dick, Laura

Publication type:

Article

Gene expression-based in vivo and in vitro prediction of liver toxicity allows compound selection at an early stage of drug development.

Published in:

Journal of Biochemical & Molecular Toxicology, 2011, v. 25, n. 3, p. 183, doi. 10.1002/jbt.20375

By:

Roth, Adrian;
Boess, Franziska;
Landes, Christian;
Steiner, Guido;
Freichel, Christian;
Plancher, Jean-Marc;
Raab, Susanne;
de Vera Mudry, Cristina;
Weiser, Thomas;
Suter, Laura

Publication type:

Article

A Perfused In Vitro Human iPSC-Derived Blood–Brain Barrier Faithfully Mimics Transferrin Receptor-Mediated Transcytosis of Therapeutic Antibodies.

Published in:

Cellular & Molecular Neurobiology, 2023, v. 43, n. 8, p. 4173, doi. 10.1007/s10571-023-01404-x

By:

Burgio, Floriana;
Gaiser, Carine;
Brady, Kevin;
Gatta, Viviana;
Class, Reiner;
Schrage, Ramona;
Suter-Dick, Laura

Publication type:

Article

The rat liver mitochondrial proteins.

Published in:

Electrophoresis, 2002, v. 23, n. 2, p. 311, doi. 10.1002/1522-2683(200202)23:2<311::AID-ELPS311>3.0.CO;2-0

By:

Fountoulakis, Michael;
Berndt, Peter;
Langen, Hanno;
Suter, Laura

Publication type:

Article

Decreased translation of Dio3 mRNA is associated with drug-induced hepatotoxicity.

Published in:

Biochemical Journal, 2013, v. 453, n. 1, p. 71, doi. 10.1042/BJ20130049

By:

DUDEK, Kate M.;
SUTER, Laura;
DARRAS, Veerle M.;
MARCZYLO, Emma L.;
GANT, Timothy W.

Publication type:

Article

Identification of Metabolites, Clinical Chemistry Markers and Transcripts Associated with Hepatotoxicity.

Published in:

PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0097249

By:

Buness, Andreas;
Roth, Adrian;
Herrmann, Annika;
Schmitz, Oliver;
Kamp, Hennicke;
Busch, Kristina;
Suter, Laura

Publication type:

Article

Bioengineered 3D Human Kidney Tissue, a Platform for the Determination of Nephrotoxicity.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0059219

By:

DesRochers, Teresa M.;
Suter, Laura;
Roth, Adrian;
Kaplan, David L.

Publication type:

Article

How to Foster 'New Approach Methodology' Toxicologists.

Published in:

Alternatives to Laboratory Animals, 2022, v. 50, n. 1, p. 71, doi. 10.1177/02611929221078945

By:

Doktorova, Tatyana Y.;
Azzi, Pamela;
Hofer, Joelle;
Messner, Catherine J.;
Gaiser, Carine;
Werner, Sophie;
Singh, Pranika;
Hardy, Barry;
Suter-Dick, Laura;
Chesne, Christophe

Publication type:

Article

Gene Expression Analysis of the Hepatotoxicant Methapyrilene in Primary Rat Hepatocytes: An Interlaboratory Study.

Published in:

Environmental Health Perspectives, 2006, v. 114, n. 1, p. 92, doi. 10.1289/ehp.7915

By:

Beekman, Johanna M.;
Boess, Franziska;
Hildebrand, Heinrich;
Kalkuhl, Arno;
Suter, Laura

Publication type:

Article

Discriminating Different Classes of Toxicants by Transcript Profiling.

Published in:

Environmental Health Perspectives, 2004, v. 112, n. 12, p. 1236, doi. 10.1289/txg.7036

By:

Steiner, Guido;
Suter, Laura;
Boess, Franziska;
Gasser, Rodolfo;
de Vera, Maria Cristina;
Albertini, Silvio;
Ruepp, Stefan

Publication type:

Article

Coplanar embedding of multiple 3D cell models in hydrogel towards high-throughput micro-histology.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-13987-4

By:

Heub, Sarah;
Navaee, Fatemeh;
Migliozzi, Daniel;
Ledroit, Diane;
Boder-Pasche, Stéphanie;
Goldowsky, Jonas;
Vuille-Dit-Bille, Emilie;
Hofer, Joëlle;
Gaiser, Carine;
Revol, Vincent;
Suter-Dick, Laura;
Weder, Gilles

Publication type:

Article

Two-dimensional database of mouse liver proteins. An update.

Published in:

Electrophoresis, 2001, v. 22, n. 9, p. 1747, doi. 10.1002/1522-2683(200105)22:9<1747::AID-ELPS1747>3.0.CO;2-H

By:

Fountoulakis, Michael;
Juranville, Jean-François;
Berndt, Peter;
Langen, Hanno;
Suter, Laura

Publication type:

Article

Two-dimensional database of mouse liver proteins: Changes in hepatic protein levels following treatment with acetaminophen or its nontoxic regioisomer 3-acetamidophenol.

Published in:

Electrophoresis, 2000, v. 21, n. 11, p. 2148, doi. 10.1002/1522-2683(20000601)21:11<2148::AID-ELPS2148>3.0.CO;2-X

By:

Fountoulakis, Michael;
Berndt, Peter;
Boelsterli, Urs A.;
Crameri, Flavio;
Winter, Michael;
Albertini, Silvio;
Suter, Laura

Publication type:

Article