Works by Sulzer, David

Results: 100

Differential memory enrichment of cytotoxic CD4 T cells in Parkinson's disease patients reactive to α-synuclein.

Published in:

NPJ Parkinson's Disease, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41531-025-00981-6

By:

Freuchet, Antoine;
Johansson, Emil;
Frazier, April;
Litvan, Irene;
Goldman, Jennifer G.;
Alcalay, Roy N.;
Sulzer, David;
Lindestam Arlehamn, Cecilia S.;
Sette, Alessandro

Publication type:

Article

Autoimmunity in Parkinson's Disease: The Role of α-Synuclein-Specific T Cells.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00303

By:

Garretti, Francesca;
Agalliu, Dritan;
Lindestam Arlehamn, Cecilia S.;
Sette, Alessandro;
Sulzer, David

Publication type:

Article

Behavioral phenotyping and dopamine dynamics in mice with conditional deletion of the glutamate transporter GLT-1 in neurons: resistance to the acute locomotor effects of amphetamine.

Published in:

Psychopharmacology, 2018, v. 235, n. 5, p. 1371, doi. 10.1007/s00213-018-4848-1

By:

Fischer, Kathryn D.;
Houston, Alex C. W.;
Desai, Rajeev I.;
Doyle, Michelle R.;
Bergman, Jack;
Mian, Maha;
Mannix, Rebekah;
Sulzer, David L.;
Choi, Se Joon;
Mosharov, Eugene V.;
Hodgson, Nathaniel W.;
Bechtholt, Anita;
Miczek, Klaus A.;
Rosenberg, Paul A.

Publication type:

Article

Norepinephrine release in the cerebellum contributes to aversive learning.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40548-8

By:

Stanley, Adrien T.;
Post, Michael R.;
Lacefield, Clay;
Sulzer, David;
Miniaci, Maria Concetta

Publication type:

Article

Atomic C 6 dispersion coefficients: a four-component relativistic Kohn–Sham study.

Published in:

Molecular Physics, 2012, v. 110, n. 19/20, p. 2535, doi. 10.1080/00268976.2012.709283

By:

Sulzer, David;
Norman, Patrick;
Saue, Trond

Publication type:

Article

AGAP1/AP-3-dependent endocytic recycling of M<sub>5</sub> muscarinic receptors promotes dopamine release.

Published in:

EMBO Journal, 2010, v. 29, n. 16, p. 2813, doi. 10.1038/emboj.2010.154

By:

Bendor, Jacob;
Lizardi-Ortiz, José E.;
Westphalen, Robert I.;
Brandstetter, Markus;
Hemmings Jr., Hugh C.;
Sulzer, David;
Flajolet, Marc;
Greengard, Paul

Publication type:

Article

Direct Pathway Neurons in the Mouse Ventral Striatum Are Active During Goal-Directed Action but Not Reward Consumption During Operant Conditioning.

Published in:

Biomedicines, 2024, v. 12, n. 12, p. 2755, doi. 10.3390/biomedicines12122755

By:

Cataldi, Stefano;
Lacefield, Clay;
Shashaank, N;
Sulzer, David

Publication type:

Article

Subcellular proteomics of dopamine neurons in the mouse brain.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.70921

By:

Hobson, Benjamin D.;
Se Joon Choi;
Mosharov, Eugene V.;
Soni, Rajesh K.;
Sulzer, David;
Sims, Peter A.

Publication type:

Article

The TCR repertoire of α-synuclein-specific T cells in Parkinson's disease is surprisingly diverse.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-79726-9

By:

Singhania, Akul;
Pham, John;
Dhanwani, Rekha;
Frazier, April;
Rezende Dutra, Juliana;
Marder, Karen S.;
Phillips, Elizabeth;
Mallal, Simon;
Amara, Amy W.;
Standaert, David G.;
Sulzer, David;
Peters, Bjoern;
Sette, Alessandro;
Lindestam Arlehamn, Cecilia S.

Publication type:

Article

Designing a norepinephrine optical tracer for imaging individual noradrenergic synapses and their activity in vivo.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05075-x

By:

Dunn, Matthew;
Henke, Adam;
Clark, Samuel;
Kovalyova, Yekaterina;
Kempadoo, Kimberly A.;
Karpowicz, Richard J.;
Kandel, Eric R.;
Sulzer, David;
Sames, Dalibor

Publication type:

Article

α-Synuclein Overexpression in PC12 and Chromaffin Cells Impairs Catecholamine Release by Interfering with a Late Step in Exocytosis.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 46, p. 24, doi. 10.1523/JNEUROSCI.3821-06.2006

By:

Larsen, Kristin E.;
Schmitz, Yvonne;
Troyer, Matthew D.;
Mosharov, Eugene;
Dietrich, Paula;
Quazi, Abrar Z.;
Savalle, Magali;
Nemani, Venu;
Chaudhry, Farrukh A.;
Edwards, Robert H.;
Stefanis, Leonidas;
Sulzer, David

Publication type:

Article

α-Synuclein Overexpression Increases Cytosolic Catecholamine Concentration.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 36, p. 9304, doi. 10.1523/JNEUROSCI.0519-06.2006

By:

Mosharov, Eugene V.;
Staal, Roland G. W.;
Bove, Jordi;
Prou, Delphine;
Hananiya, Anthonia;
Markov, Dmitriy;
Poulsen, Nathan;
Larsen, Kristin E.;
Moore, Candace M. H.;
Troyer, Matthew D.;
Edwards, Robert H.;
Przedborski, Serge;
Sulzer, David

Publication type:

Article

Regulation of the Development of Mesencephalic Dopaminergic Systems by the Selective Expression of Glial Cell Line-Derived Neurotrophic Factor in Their Targets.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 12, p. 3136, doi. 10.1523/JNEUROSCI.4506-03.2004

By:

Kholodilov, Nikolai;
Yarygina, Olga;
Oo, Tinmarla Frances;
Hui Zhang;
Sulzer, David;
Dauer, William;
Burke, Robert E.

Publication type:

Article

Dopamine Neurons Mediate a Fast Excitatory Signal via Their Glutamatergic Synapses.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 4, p. 972, doi. 10.1523/JNEUROSCI.4317-03.2004

By:

Nao Chuhma, Rolf-Detlef;
Hui Zhang;
Masson, Justine;
Xiaoxi Zhuang;
Sulzer, David;
Hen, René;
Rayport, Stephen

Publication type:

Article

Glutamate Spillover in the Striatum Depresses Dopaminergic Transmission by Activating Group I Metabotropic Glutamate Receptors.

Published in:

Journal of Neuroscience, 2003, v. 23, n. 33, p. 10585, doi. 10.1523/JNEUROSCI.23-33-10585.2003

By:

Zhang, Hui;
Sulzer, David

Publication type:

Article

Interpreting the role of the striatum during multiple phases of motor learning.

Published in:

FEBS Journal, 2022, v. 289, n. 8, p. 2263, doi. 10.1111/febs.15908

By:

Cataldi, Stefano;
Stanley, Adrien T.;
Miniaci, Maria Concetta;
Sulzer, David

Publication type:

Article

Involvement of Autophagy in Levodopa‐Induced Dyskinesia.

Published in:

Movement Disorders, 2021, v. 36, n. 5, p. 1137, doi. 10.1002/mds.28480

By:

Feyder, Michael;
Plewnia, Carina;
Lieberman, Ori J.;
Spigolon, Giada;
Piccin, Alessandro;
Urbina, Lidia;
Dehay, Benjamin;
Li, Qin;
Nilsson, Per;
Altun, Mikael;
Santini, Emanuela;
Sulzer, David;
Bezard, Erwan;
Borgkvist, Anders;
Fisone, Gilberto

Publication type:

Article

Inflammation in Experimental Models of α‐Synucleinopathies.

Published in:

Movement Disorders, 2021, v. 36, n. 1, p. 37, doi. 10.1002/mds.28264

By:

Harms, Ashley S.;
Kordower, Jeffrey H.;
Sette, Alessandro;
Lindestam Arlehamn, Cecilia S.;
Sulzer, David;
Mach, Robert H.

Publication type:

Article

In memoriam: Robert E. Burke, MD, 1949-2018.

Published in:

2019

By:

Fahn, Stanley;
Sulzer, David;
Kang, Un Jung;
Bressman, Susan

Publication type:

journal article

Presynaptic effects of levodopa and their possible role in dyskinesia.

Published in:

Movement Disorders, 2015, v. 30, n. 1, p. 45, doi. 10.1002/mds.26103

By:

Mosharov, Eugene V.;
Borgkvist, Anders;
Sulzer, David

Publication type:

Article

ApoE4 upregulates the activity of mitochondria-associated ER membranes.

Published in:

EMBO Reports, 2016, v. 17, n. 1, p. 27, doi. 10.15252/embr.201540614

By:

Tambini, Marc D;
Pera, Marta;
Kanter, Ellen;
Yang, Hua;
Guardia‐Laguarta, Cristina;
Holtzman, David;
Sulzer, David;
Area‐Gomez, Estela;
Schon, Eric A

Publication type:

Article

Mice transgenic for exon 1 of the Huntington's disease gene display reduced striatal sensitivity to neurotoxicity induced by dopamine and 6-hydroxydopamine.

Published in:

European Journal of Neuroscience, 2001, v. 14, n. 9, p. 1425, doi. 10.1046/j.0953-816X.2001.01765.x

By:

Petersén, Åsa;
Hansson, Oskar;
Puschban, Zoe;
Sapp, Ellen;
Romero, Norma;
Castilho, Roger F.;
Sulzer, David;
Rice, Margaret;
DiFiglia, Marian;
Przedborski, Serge;
Brundin, Patrik

Publication type:

Article

Dopamine, Oxidative Stress and Protein–Quinone Modifications in Parkinson's and Other Neurodegenerative Diseases.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 20, p. 6512, doi. 10.1002/anie.201811122

By:

Monzani, Enrico;
Nicolis, Stefania;
Dell'Acqua, Simone;
Capucciati, Andrea;
Bacchella, Chiara;
Zucca, Fabio A.;
Mosharov, Eugene V.;
Sulzer, David;
Zecca, Luigi;
Casella, Luigi

Publication type:

Article

NeuO: a Fluorescent Chemical Probe for Live Neuron Labeling.

Published in:

Angewandte Chemie International Edition, 2015, v. 54, n. 8, p. 2442, doi. 10.1002/anie.201408614

By:

Er, Jun Cheng;
Leong, Cheryl;
Teoh, Chai Lean;
Yuan, Qiang;
Merchant, Paolomi;
Dunn, Matthew;
Sulzer, David;
Sames, Dalibor;
Bhinge, Akshay;
Kim, Dongyoon;
Kim, Seong-Min;
Yoon, Myung-Han;
Stanton, Lawrence W.;
Je, Shawn H.;
Yun, Seong-Wook;
Chang, Young-Tae

Publication type:

Article

Loss of VGLUT3 Produces Circadian-Dependent Hyperdopaminergia and Ameliorates Motor Dysfunction and L-Dopa-Mediated Dyskinesias in a Model of Parkinson's Disease.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 45, p. 14983, doi. 10.1523/JNEUROSCI.2124-15.2015

By:

Divito, Christopher B.;
Steece-Collier, Kathy;
Case, Daniel T.;
Williams, Sean-Paul G.;
Stancati, Jennifer A.;
Lianteng Zhi;
Rubio, Maria E.;
Sortwell, Caryl E.;
Collier, Timothy J.;
Sulzer, David;
Edwards, Robert H.;
Hui Zhang;
Seal, Rebecca P.

Publication type:

Article

M<sub>5</sub> Receptor Activation Produces Opposing Physiological Outcomes in Dopamine Neurons Depending on the Receptor's Location.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 9, p. 3253, doi. 10.1523/JNEUROSCI.4896-13.2014

By:

Foster, Daniel J.;
Gentry, Patrick R.;
Lizardi-Ortiz, Jose E.;
Bridges, Thomas M.;
Wood, Michael R.;
Niswender, Colleen M.;
Sulzer, David;
Lindsley, Craig W.;
Zixiu Xiang;
Conn, P. Jeffrey

Publication type:

Article

Glycine Transporter-1 Inhibition Promotes Striatal Axon Sprouting via NMDA Receptors in Dopamine Neurons.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 42, p. 16778, doi. 10.1523/JNEUROSCI.3041-12.2013

By:

Schmitz, Yvonne;
Castagna, Candace;
Mrejeru, Ana;
Lizardi-Ortiz, José E.;
Klein, Zoe;
Lindsley, Craig W.;
Sulzer, David

Publication type:

Article

ATF4 Protects Against Neuronal Death in Cellular Parkinson's Disease Models by Maintaining Levels of Parkin.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 6, p. 2398, doi. 10.1523/JNEUROSCI.2292-12.2013

By:

Xiaotian Sun;
Jin Liu;
Crary, John F.;
Malagelada, Cristina;
Sulzer, David;
Greene, Lloyd A.;
Levy, Oren A.

Publication type:

Article

Calcium currents regulate dopamine autoreceptors.

Published in:

Brain: A Journal of Neurology, 2014, v. 137, n. 8, p. 2113, doi. 10.1093/brain/awu150

By:

Borgkvist, Anders;
Mosharov, Eugene V.;
Sulzer, David

Publication type:

Article

α-synuclein and cytosolic dopamine: Stabilizing a bad situation.

Published in:

Nature Medicine, 2001, v. 7, n. 12, p. 1280, doi. 10.1038/nm1201-1280

By:

Sulzer, David

Publication type:

Article

Dopamin, oxidativer Stress und Protein‐Chinonmodifikationen bei Parkinson und anderen neurodegenerativen Erkrankungen.

Published in:

Angewandte Chemie, 2019, v. 131, n. 20, p. 6580, doi. 10.1002/ange.201811122

By:

Monzani, Enrico;
Nicolis, Stefania;
Dell'Acqua, Simone;
Capucciati, Andrea;
Bacchella, Chiara;
Zucca, Fabio A.;
Mosharov, Eugene V.;
Sulzer, David;
Zecca, Luigi;
Casella, Luigi

Publication type:

Article

NeuO: a Fluorescent Chemical Probe for Live Neuron Labeling.

Published in:

Angewandte Chemie, 2015, v. 127, n. 8, p. 2472, doi. 10.1002/ange.201408614

By:

Er, Jun Cheng;
Leong, Cheryl;
Teoh, Chai Lean;
Yuan, Qiang;
Merchant, Paolomi;
Dunn, Matthew;
Sulzer, David;
Sames, Dalibor;
Bhinge, Akshay;
Kim, Dongyoon;
Kim, Seong-Min;
Yoon, Myung-Han;
Stanton, Lawrence W.;
Je, Shawn H.;
Yun, Seong-Wook;
Chang, Young-Tae

Publication type:

Article

Neuronal vulnerability, pathogenesis, and Parkinson's disease.

Published in:

Movement Disorders, 2013, v. 28, n. 6, p. 715, doi. 10.1002/mds.25187

By:

Sulzer, David;
Surmeier, D. James

Publication type:

Article

Neuronal vulnerability, pathogenesis, and Parkinson's disease.

Published in:

Movement Disorders, 2013, v. 28, n. 1, p. 41, doi. 10.1002/mds.25095

By:

Sulzer, David;
Surmeier, D. James

Publication type:

Article

Clues to how alpha-synuclein damages neurons in Parkinson's disease.

Published in:

Movement Disorders, 2010, v. 25, n. S1, p. S27, doi. 10.1002/mds.22639

By:

Sulzer, David

Publication type:

Article

Neuronal MHC-I expression and its implications in synaptic function, axonal regeneration and Parkinson's and other brain diseases.

Published in:

Frontiers in Neuroanatomy, 2014, v. 8, p. 1, doi. 10.3389/fnana.2014.00114

By:

Cebrián, Carolina;
Loike, John D.;
Sulzer, David

Publication type:

Article

Coordinated Postnatal Maturation of Striatal Cholinergic Interneurons and Dopamine Release Dynamics in Mice.

Published in:

Journal of Neuroscience, 2021, v. 41, n. 16, p. 3597, doi. 10.1523/JNEUROSCI.0755-20.2021

By:

McGuirt, Avery F.;
Post, Michael R.;
Pigulevskiy, Irena;
Sulzer, David;
Lieberman, Ori J.

Publication type:

Article

Cytokine pathway disruption in a mouse model of schizophrenia induced by Munc18-1a overexpression in the brain.

Published in:

2014

By:

Gil-Pisa, Itziar;
Cebrián, Carolina;
Ortega, Jorge E;
Meana, J Javier;
Sulzer, David

Publication type:

journal article

Lingo-1 expression is increased in essential tremor cerebellum and is present in the basket cell pinceau.

Published in:

Acta Neuropathologica, 2013, v. 125, n. 6, p. 879, doi. 10.1007/s00401-013-1108-7

By:

Kuo, Sheng-Han;
Tang, Guomei;
Louis, Elan;
Ma, Karen;
Babji, Rachel;
Balatbat, Matthew;
Cortes, Etty;
Vonsattel, Jean-Paul;
Yamamoto, Ai;
Sulzer, David;
Faust, Phyllis

Publication type:

Article

SNAREs can promote complete Fusion and hemifusion as alternative outcomes.

Published in:

Journal of Cell Biology, 2005, v. 170, n. 2, p. 249, doi. 10.1083/jcb.200501093

By:

Giraudo, Claudio G.;
Chuan Hu;
Daoqi You;
Slovic, Avram M.;
Mosharov, Eugene V.;
Sulzer, David;
Melia, Thomas J.;
Rothman, James E.

Publication type:

Article

Stimulation-dependent regulation of the ph, volume and quantal size of bovine and rodent secretory vesicles.

Published in:

Journal of Physiology, 2002, v. 542, n. 2, p. 453, doi. 10.1113/jphysiol.2002.018630

By:

Pothos, Emmanuel N.;
Mosharov, Eugene;
Liu, Kuo-Peing;
Setlik, Wanda;
Haburcak, Marian;
Baldini, Giulia;
Gershon, Michael D.;
Tamir, Hadassah;
Sulzer, David

Publication type:

Article

Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice.

Published in:

Nature Neuroscience, 2005, v. 8, n. 11, p. 1586, doi. 10.1038/nn1562

By:

Paterlini, Marta;
Zakharenko, Stanislav S.;
Wen-Sung Lai;
Jie Qin;
Hui Zhang;
Mukai, Jun;
Westphal, Koen G. C.;
Olivier, Berend;
Sulzer, David;
Pavlidis, Paul;
Siegelbaum, Steven A.;
Karayiorgou, Maria;
Gogos, Joseph A.

Publication type:

Article

Frequency-dependent modulation of dopamine release by nicotine.

Published in:

Nature Neuroscience, 2004, v. 7, n. 6, p. 581, doi. 10.1038/nn1243

By:

Hui Zhang;
Sulzer, David

Publication type:

Article

Dopamine neurons release transmitter via a flickering fusion pore.

Published in:

Nature Neuroscience, 2004, v. 7, n. 4, p. 341, doi. 10.1038/nn1205

By:

Staal, Roland G. W.;
Mosharov, Eugene V.;
Sulzer, David

Publication type:

Article

Optogenetics enables functional analysis of human embryonic stem cell-derived grafts in a Parkinson's disease model.

Published in:

Nature Biotechnology, 2015, v. 33, n. 2, p. 204, doi. 10.1038/nbt.3124

By:

Steinbeck, Julius A;
Choi, Se Joon;
Mrejeru, Ana;
Ganat, Yosif;
Deisseroth, Karl;
Sulzer, David;
Mosharov, Eugene V;
Studer, Lorenz

Publication type:

Article

The pathology roadmap in Parkinson disease.

Published in:

Prion, 2013, v. 7, n. 1, p. 85, doi. 10.4161/pri.23582

By:

Surmeier, D. James;
Sulzer, David

Publication type:

Article

Presynaptic Regulation of Dopamine Transmission in Schizophrenia.

Published in:

Schizophrenia Bulletin, 2011, v. 37, n. 1, p. 108, doi. 10.1093/schbul/sbp010

By:

Lyon, Gholson J.;
Abi-Dargham, Anissa;
Moore, Holly;
Lieberman, Jeffrey A.;
Javitch, Jonathan A.;
Sulzer, David

Publication type:

Article

Alpha-synuclein research: defining strategic moves in the battle against Parkinson's disease.

Published in:

NPJ Parkinson's Disease, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41531-021-00203-9

By:

Oliveira, Luis M. A.;
Gasser, Thomas;
Edwards, Robert;
Zweckstetter, Markus;
Melki, Ronald;
Stefanis, Leonidas;
Lashuel, Hilal A.;
Sulzer, David;
Vekrellis, Kostas;
Halliday, Glenda M.;
Tomlinson, Julianna J.;
Schlossmacher, Michael;
Jensen, Poul Henning;
Schulze-Hentrich, Julia;
Riess, Olaf;
Hirst, Warren D.;
El-Agnaf, Omar;
Mollenhauer, Brit;
Lansbury, Peter;
Outeiro, Tiago F.

Publication type:

Article

Oleh Hornykiewicz, a giant in the understanding and treatment of Parkinson disease.

Published in:

2021

By:

Zecca, Luigi;
Pifl, Christian;
Fahn, Stanley;
Sulzer, David;
Fariello, Ruggero G.

Publication type:

Editorial

COVID-19 and possible links with Parkinson's disease and parkinsonism: from bench to bedside.

Published in:

NPJ Parkinson's Disease, 2020, v. 6, n. 1, p. N.PAG, doi. 10.1038/s41531-020-00123-0

By:

Sulzer, David;
Antonini, Angelo;
Leta, Valentina;
Nordvig, Anna;
Smeyne, Richard J.;
Goldman, James E.;
Al-Dalahmah, Osama;
Zecca, Luigi;
Sette, Alessandro;
Bubacco, Luigi;
Meucci, Olimpia;
Moro, Elena;
Harms, Ashley S.;
Xu, Yaqian;
Fahn, Stanley;
Ray Chaudhuri, K.

Publication type:

Article