Works matching AU Sulzer, David

Results: 102

Neuronal Presentation of Antigen and Its Possible Role in Parkinson's Disease.

Published in:

Journal of Parkinson's Disease, 2022, v. 12, p. S137, doi. 10.3233/JPD-223153

By:

Hobson, Benjamin D.;
Sulzer, David;
Bloem, Bastiaan R.;
Brundin, Patrik;
Tan, Eng King;
Harms, Ashley;
Lindestam Arlehamn, Cecilia;
Williams-Gray, Caroline

Publication type:

Article

NeuO: a Fluorescent Chemical Probe for Live Neuron Labeling.

Published in:

Angewandte Chemie, 2015, v. 127, n. 8, p. 2472, doi. 10.1002/ange.201408614

By:

Er, Jun Cheng;
Leong, Cheryl;
Teoh, Chai Lean;
Yuan, Qiang;
Merchant, Paolomi;
Dunn, Matthew;
Sulzer, David;
Sames, Dalibor;
Bhinge, Akshay;
Kim, Dongyoon;
Kim, Seong-Min;
Yoon, Myung-Han;
Stanton, Lawrence W.;
Je, Shawn H.;
Yun, Seong-Wook;
Chang, Young-Tae

Publication type:

Article

Stimulation-dependent regulation of the ph, volume and quantal size of bovine and rodent secretory vesicles.

Published in:

Journal of Physiology, 2002, v. 542, n. 2, p. 453, doi. 10.1113/jphysiol.2002.018630

By:

Pothos, Emmanuel N.;
Mosharov, Eugene;
Liu, Kuo-Peing;
Setlik, Wanda;
Haburcak, Marian;
Baldini, Giulia;
Gershon, Michael D.;
Tamir, Hadassah;
Sulzer, David

Publication type:

Article

Autoimmunity in Parkinson's Disease: The Role of α-Synuclein-Specific T Cells.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00303

By:

Garretti, Francesca;
Agalliu, Dritan;
Lindestam Arlehamn, Cecilia S.;
Sette, Alessandro;
Sulzer, David

Publication type:

Article

Roles for α-Synuclein in Gene Expression.

Published in:

Genes, 2021, v. 12, n. 8, p. 1166, doi. 10.3390/genes12081166

By:

Somayaji, Mahalakshmi;
Lanseur, Zina;
Choi, Se Joon;
Sulzer, David;
Mosharov, Eugene V.

Publication type:

Article

α-synuclein and cytosolic dopamine: Stabilizing a bad situation.

Published in:

Nature Medicine, 2001, v. 7, n. 12, p. 1280, doi. 10.1038/nm1201-1280

By:

Sulzer, David

Publication type:

Article

Methamphetamine Inhibits Antigen Processing, Presentation, and Phagocytosis.

Published in:

PLoS Pathogens, 2008, v. 4, n. 2, p. 0001, doi. 10.1371/journal.ppat.0040028

By:

Tallóczy, Zsolt;
Martinez, Jose;
Joset, Danielle;
Ray, Yonaton;
Gácser, Attila;
Toussi, Sima;
Mizushima, Noboru;
Nosanchuk, Josh;
Goldstein, Harris;
Loike, John;
Sulzer, David;
Santambrogio, Laura

Publication type:

Article

Presynaptic effects of levodopa and their possible role in dyskinesia.

Published in:

Movement Disorders, 2015, v. 30, n. 1, p. 45, doi. 10.1002/mds.26103

By:

Mosharov, Eugene V.;
Borgkvist, Anders;
Sulzer, David

Publication type:

Article

Neuronal vulnerability, pathogenesis, and Parkinson's disease.

Published in:

Movement Disorders, 2013, v. 28, n. 6, p. 715, doi. 10.1002/mds.25187

By:

Sulzer, David;
Surmeier, D. James

Publication type:

Article

Neuronal vulnerability, pathogenesis, and Parkinson's disease.

Published in:

Movement Disorders, 2013, v. 28, n. 1, p. 41, doi. 10.1002/mds.25095

By:

Sulzer, David;
Surmeier, D. James

Publication type:

Article

Clues to how alpha-synuclein damages neurons in Parkinson's disease.

Published in:

Movement Disorders, 2010, v. 25, n. S1, p. S27, doi. 10.1002/mds.22639

By:

Sulzer, David

Publication type:

Article

Lingo-1 expression is increased in essential tremor cerebellum and is present in the basket cell pinceau.

Published in:

Acta Neuropathologica, 2013, v. 125, n. 6, p. 879, doi. 10.1007/s00401-013-1108-7

By:

Kuo, Sheng-Han;
Tang, Guomei;
Louis, Elan;
Ma, Karen;
Babji, Rachel;
Balatbat, Matthew;
Cortes, Etty;
Vonsattel, Jean-Paul;
Yamamoto, Ai;
Sulzer, David;
Faust, Phyllis

Publication type:

Article

T cell responses towards PINK1 and α-synuclein are elevated in prodromal Parkinson's disease.

Published in:

NPJ Parkinson's Disease, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41531-025-01001-3

By:

Johansson, Emil;
Freuchet, Antoine;
Williams, Gregory P.;
Michealis, Tanner;
Frazier, April;
Litvan, Irene;
Goldman, Jennifer G.;
Alcalay, Roy N.;
Standaert, David G.;
Amara, Amy W.;
Stover, Natividad;
Fon, Edward A.;
Postuma, Ronald B.;
Sidney, John;
Sulzer, David;
Lindestam Arlehamn, Cecilia S.;
Sette, Alessandro

Publication type:

Article

Differential memory enrichment of cytotoxic CD4 T cells in Parkinson's disease patients reactive to α-synuclein.

Published in:

NPJ Parkinson's Disease, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41531-025-00981-6

By:

Freuchet, Antoine;
Johansson, Emil;
Frazier, April;
Litvan, Irene;
Goldman, Jennifer G.;
Alcalay, Roy N.;
Sulzer, David;
Lindestam Arlehamn, Cecilia S.;
Sette, Alessandro

Publication type:

Article

SNAREs can promote complete Fusion and hemifusion as alternative outcomes.

Published in:

Journal of Cell Biology, 2005, v. 170, n. 2, p. 249, doi. 10.1083/jcb.200501093

By:

Giraudo, Claudio G.;
Chuan Hu;
Daoqi You;
Slovic, Avram M.;
Mosharov, Eugene V.;
Sulzer, David;
Melia, Thomas J.;
Rothman, James E.

Publication type:

Article

Subcellular proteomics of dopamine neurons in the mouse brain.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.70921

By:

Hobson, Benjamin D.;
Se Joon Choi;
Mosharov, Eugene V.;
Soni, Rajesh K.;
Sulzer, David;
Sims, Peter A.

Publication type:

Article

Frequency-dependent modulation of dopamine release by nicotine.

Published in:

Nature Neuroscience, 2004, v. 7, n. 6, p. 581, doi. 10.1038/nn1243

By:

Hui Zhang;
Sulzer, David

Publication type:

Article

Dopamine neurons release transmitter via a flickering fusion pore.

Published in:

Nature Neuroscience, 2004, v. 7, n. 4, p. 341, doi. 10.1038/nn1205

By:

Staal, Roland G. W.;
Mosharov, Eugene V.;
Sulzer, David

Publication type:

Article

Atomic C 6 dispersion coefficients: a four-component relativistic Kohn–Sham study.

Published in:

Molecular Physics, 2012, v. 110, n. 19/20, p. 2535, doi. 10.1080/00268976.2012.709283

By:

Sulzer, David;
Norman, Patrick;
Saue, Trond

Publication type:

Article

Macroautophagy Abnormality in Essential Tremor.

Published in:

PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0053040

By:

Kuo, Sheng-Han;
Tang, Guomei;
Ma, Karen;
Babij, Rachel;
Cortes, Etty;
Vonsattel, Jean-Paul G.;
Faust, Phyllis L.;
Sulzer, David;
Louis, Elan D.

Publication type:

Article

Regulation of the Development of Mesencephalic Dopaminergic Systems by the Selective Expression of Glial Cell Line-Derived Neurotrophic Factor in Their Targets.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 12, p. 3136, doi. 10.1523/JNEUROSCI.4506-03.2004

By:

Kholodilov, Nikolai;
Yarygina, Olga;
Oo, Tinmarla Frances;
Hui Zhang;
Sulzer, David;
Dauer, William;
Burke, Robert E.

Publication type:

Article

Dopamine Neurons Mediate a Fast Excitatory Signal via Their Glutamatergic Synapses.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 4, p. 972, doi. 10.1523/JNEUROSCI.4317-03.2004

By:

Nao Chuhma, Rolf-Detlef;
Hui Zhang;
Masson, Justine;
Xiaoxi Zhuang;
Sulzer, David;
Hen, René;
Rayport, Stephen

Publication type:

Article

Glutamate Spillover in the Striatum Depresses Dopaminergic Transmission by Activating Group I Metabotropic Glutamate Receptors.

Published in:

Journal of Neuroscience, 2003, v. 23, n. 33, p. 10585, doi. 10.1523/JNEUROSCI.23-33-10585.2003

By:

Zhang, Hui;
Sulzer, David

Publication type:

Article

Behavioral phenotyping and dopamine dynamics in mice with conditional deletion of the glutamate transporter GLT-1 in neurons: resistance to the acute locomotor effects of amphetamine.

Published in:

Psychopharmacology, 2018, v. 235, n. 5, p. 1371, doi. 10.1007/s00213-018-4848-1

By:

Fischer, Kathryn D.;
Houston, Alex C. W.;
Desai, Rajeev I.;
Doyle, Michelle R.;
Bergman, Jack;
Mian, Maha;
Mannix, Rebekah;
Sulzer, David L.;
Choi, Se Joon;
Mosharov, Eugene V.;
Hodgson, Nathaniel W.;
Bechtholt, Anita;
Miczek, Klaus A.;
Rosenberg, Paul A.

Publication type:

Article

mTOR Suppresses Macroautophagy During Striatal Postnatal Development and Is Hyperactive in Mouse Models of Autism Spectrum Disorders.

Published in:

Frontiers in Cellular Neuroscience, 2020, p. 1, doi. 10.3389/fncel.2020.00070

By:

Lieberman, Ori J.;
Cartocci, Veronica;
Pigulevskiy, Irena;
Molinari, Maya;
Carbonell, Josep;
Broseta, Miguel Bellés;
Post, Michael R.;
Sulzer, David;
Borgkvist, Anders;
Santini, Emanuela

Publication type:

Article

Misfolded GBA/β-glucocerebrosidase impairs ER-quality control by chaperone-mediated autophagy in Parkinson disease.

Published in:

Autophagy, 2022, v. 18, n. 12, p. 3050, doi. 10.1080/15548627.2022.2071383

By:

Kuo, Sheng-Han;
Tasset, Inmaculada;
Cuervo, Ana Maria;
Sulzer, David

Publication type:

Article

Autophagic bias in the striatum.

Published in:

Autophagy, 2020, v. 16, n. 6, p. 1148, doi. 10.1080/15548627.2020.1743070

By:

Pigulevskiy, Irena;
Lieberman, Ori J.;
Sulzer, David

Publication type:

Article

Mitochondrial dysfunction and mitophagy defect triggered by heterozygous GBA mutations.

Published in:

Autophagy, 2019, v. 15, n. 1, p. 113, doi. 10.1080/15548627.2018.1509818

By:

Li, Hongyu;
Ham, Ahrom;
Ma, Thong Chi;
Kuo, Sheng-Han;
Kanter, Ellen;
Kim, Donghoon;
Ko, Han Seok;
Quan, Yi;
Sardi, Sergio Pablo;
Li, Aiqun;
Arancio, Ottavio;
Kang, Un Jung;
Sulzer, David;
Tang, Guomei

Publication type:

Article

Calcium currents regulate dopamine autoreceptors.

Published in:

Brain: A Journal of Neurology, 2014, v. 137, n. 8, p. 2113, doi. 10.1093/brain/awu150

By:

Borgkvist, Anders;
Mosharov, Eugene V.;
Sulzer, David

Publication type:

Article

Loss of VGLUT3 Produces Circadian-Dependent Hyperdopaminergia and Ameliorates Motor Dysfunction and L-Dopa-Mediated Dyskinesias in a Model of Parkinson's Disease.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 45, p. 14983, doi. 10.1523/JNEUROSCI.2124-15.2015

By:

Divito, Christopher B.;
Steece-Collier, Kathy;
Case, Daniel T.;
Williams, Sean-Paul G.;
Stancati, Jennifer A.;
Lianteng Zhi;
Rubio, Maria E.;
Sortwell, Caryl E.;
Collier, Timothy J.;
Sulzer, David;
Edwards, Robert H.;
Hui Zhang;
Seal, Rebecca P.

Publication type:

Article

M<sub>5</sub> Receptor Activation Produces Opposing Physiological Outcomes in Dopamine Neurons Depending on the Receptor's Location.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 9, p. 3253, doi. 10.1523/JNEUROSCI.4896-13.2014

By:

Foster, Daniel J.;
Gentry, Patrick R.;
Lizardi-Ortiz, Jose E.;
Bridges, Thomas M.;
Wood, Michael R.;
Niswender, Colleen M.;
Sulzer, David;
Lindsley, Craig W.;
Zixiu Xiang;
Conn, P. Jeffrey

Publication type:

Article

Glycine Transporter-1 Inhibition Promotes Striatal Axon Sprouting via NMDA Receptors in Dopamine Neurons.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 42, p. 16778, doi. 10.1523/JNEUROSCI.3041-12.2013

By:

Schmitz, Yvonne;
Castagna, Candace;
Mrejeru, Ana;
Lizardi-Ortiz, José E.;
Klein, Zoe;
Lindsley, Craig W.;
Sulzer, David

Publication type:

Article

ATF4 Protects Against Neuronal Death in Cellular Parkinson's Disease Models by Maintaining Levels of Parkin.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 6, p. 2398, doi. 10.1523/JNEUROSCI.2292-12.2013

By:

Xiaotian Sun;
Jin Liu;
Crary, John F.;
Malagelada, Cristina;
Sulzer, David;
Greene, Lloyd A.;
Levy, Oren A.

Publication type:

Article

Dual Control of Dopamine Synthesis and Release by Presynaptic and Postsynaptic Dopamine D2 Receptors.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 26, p. 9023, doi. 10.1523/JNEUROSCI.0918-12.2012

By:

Anzalone, Andrea;
Lizardi-Ortiz, José E.;
Ramos, Maria;
De Mei, Claudia;
Hopf, F. Woodward;
Iaccarino, Ciro;
Halbout, Briac;
Jacobsen, Jacob;
Kinoshita, Chisato;
Welter, Marc;
Caron, Marc G.;
Bonci, Antonello;
Sulzer, David;
Borrelli, Emiliana

Publication type:

Article

Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy.

Published in:

2008

By:

Martinez-Vicente, Marta;
Talloczy, Zsolt;
Kaushik, Susmita;
Massey, Ashish C.;
Mazzulli, Joseph;
Mosharov, Eugene V.;
Hodara, Roberto;
Fredenburg, Ross;
Du-Chu Wu;
Follenzi, Antonia;
Dauer, William;
Przedborski, Serge;
Ischiropoulos, Harry;
Lansbury, Peter T.;
Sulzer, David;
Cuervo, Ana Maria;
Wu, Du-Chu

Publication type:

journal article

Neuromelanin of the Human Substantia Nigra: An Update.

Published in:

Neurotoxicity Research, 2014, v. 25, n. 1, p. 13, doi. 10.1007/s12640-013-9435-y

By:

Zucca, Fabio;
Basso, Emy;
Cupaioli, Francesca;
Ferrari, Emanuele;
Sulzer, David;
Casella, Luigi;
Zecca, Luigi

Publication type:

Article

Neuromelanin Activates Microglia and Induces Degeneration of Dopaminergic Neurons: Implications for Progression of Parkinson's Disease.

Published in:

Neurotoxicity Research, 2011, v. 19, n. 1, p. 63, doi. 10.1007/s12640-009-9140-z

By:

Zhang, Wei;
Phillips, Kester;
Wielgus, Albert;
Liu, Jie;
Albertini, Alberto;
Zucca, Fabio;
Faust, Rudolph;
Qian, Steven;
Miller, David;
Chignell, Colin;
Wilson, Belinda;
Jackson-Lewis, Vernice;
Przedborski, Serge;
Joset, Danielle;
Loike, John;
Hong, Jau-Shyong;
Sulzer, David;
Zecca, Luigi

Publication type:

Article

Interplay of LRRK2 with chaperone-mediated autophagy.

Published in:

Nature Neuroscience, 2013, v. 16, n. 4, p. 394, doi. 10.1038/nn.3350

By:

Orenstein, Samantha J;
Kuo, Sheng-Han;
Tasset, Inmaculada;
Arias, Esperanza;
Koga, Hiroshi;
Fernandez-Carasa, Irene;
Cortes, Etty;
Honig, Lawrence S;
Dauer, William;
Consiglio, Antonella;
Raya, Angel;
Sulzer, David;
Cuervo, Ana Maria

Publication type:

Article

Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease.

Published in:

Nature Neuroscience, 2010, v. 13, n. 5, p. 567, doi. 10.1038/nn.2528

By:

Martinez-Vicente, Marta;
Talloczy, Zsolt;
Wong, Esther;
Guomei Tang;
Koga, Hiroshi;
Kaushik, Susmita;
de Vries, Rosa;
Arias, Esperanza;
Harris, Spike;
Sulzer, David;
Cuervo, Ana Maria

Publication type:

Article

Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice.

Published in:

Nature Neuroscience, 2005, v. 8, n. 11, p. 1586, doi. 10.1038/nn1562

By:

Paterlini, Marta;
Zakharenko, Stanislav S.;
Wen-Sung Lai;
Jie Qin;
Hui Zhang;
Mukai, Jun;
Westphal, Koen G. C.;
Olivier, Berend;
Sulzer, David;
Pavlidis, Paul;
Siegelbaum, Steven A.;
Karayiorgou, Maria;
Gogos, Joseph A.

Publication type:

Article

Expanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration.

Published in:

Human Molecular Genetics, 2001, v. 10, n. 12, p. 1243, doi. 10.1093/hmg/10.12.1243

By:

Petersén, Åsa;
Larsen, Kristin E.;
Behr, Gerald G.;
Romero, Norma;
Przedborski, Serge;
Brundin, Patrik;
Sulzer, David

Publication type:

Article

Designing a norepinephrine optical tracer for imaging individual noradrenergic synapses and their activity in vivo.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05075-x

By:

Dunn, Matthew;
Henke, Adam;
Clark, Samuel;
Kovalyova, Yekaterina;
Kempadoo, Kimberly A.;
Karpowicz, Richard J.;
Kandel, Eric R.;
Sulzer, David;
Sames, Dalibor

Publication type:

Article

The absolute concentration of nigral neuromelanin, assayed by a new sensitive method, increases throughout the life and is dramatically decreased in Parkinson’s disease

Published in:

FEBS Letters, 2002, v. 510, n. 3, p. 216, doi. 10.1016/S0014-5793(01)03269-0

By:

Zecca, Luigi;
Fariello, Ruggero;
Riederer, Peter;
Sulzer, David;
Gatti, Alberto;
Tampellini, Davide

Publication type:

Article

Interpreting the role of the striatum during multiple phases of motor learning.

Published in:

FEBS Journal, 2022, v. 289, n. 8, p. 2263, doi. 10.1111/febs.15908

By:

Cataldi, Stefano;
Stanley, Adrien T.;
Miniaci, Maria Concetta;
Sulzer, David

Publication type:

Article

ApoE4 upregulates the activity of mitochondria-associated ER membranes.

Published in:

EMBO Reports, 2016, v. 17, n. 1, p. 27, doi. 10.15252/embr.201540614

By:

Tambini, Marc D;
Pera, Marta;
Kanter, Ellen;
Yang, Hua;
Guardia‐Laguarta, Cristina;
Holtzman, David;
Sulzer, David;
Area‐Gomez, Estela;
Schon, Eric A

Publication type:

Article

Oleh Hornykiewicz, a giant in the understanding and treatment of Parkinson disease.

Published in:

2021

By:

Zecca, Luigi;
Pifl, Christian;
Fahn, Stanley;
Sulzer, David;
Fariello, Ruggero G.

Publication type:

Editorial

COVID-19 and possible links with Parkinson's disease and parkinsonism: from bench to bedside.

Published in:

NPJ Parkinson's Disease, 2020, v. 6, n. 1, p. N.PAG, doi. 10.1038/s41531-020-00123-0

By:

Sulzer, David;
Antonini, Angelo;
Leta, Valentina;
Nordvig, Anna;
Smeyne, Richard J.;
Goldman, James E.;
Al-Dalahmah, Osama;
Zecca, Luigi;
Sette, Alessandro;
Bubacco, Luigi;
Meucci, Olimpia;
Moro, Elena;
Harms, Ashley S.;
Xu, Yaqian;
Fahn, Stanley;
Ray Chaudhuri, K.

Publication type:

Article

Neuromelanin organelles are specialized autolysosomes that accumulate undegraded proteins and lipids in aging human brain and are likely involved in Parkinson's disease.

Published in:

NPJ Parkinson's Disease, 2018, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41531-018-0050-8

By:

Zucca, Fabio A.;
Vanna, Renzo;
Cupaioli, Francesca A.;
Bellei, Chiara;
De Palma, Antonella;
Di Silvestre, Dario;
Mauri, Pierluigi;
Grassi, Sara;
Prinetti, Alessandro;
Casella, Luigi;
Sulzer, David;
Zecca, Luigi

Publication type:

Article

Neuromelanin detection by magnetic resonance imaging (MRI) and its promise as a biomarker for Parkinson's disease.

Published in:

NPJ Parkinson's Disease, 2018, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41531-018-0047-3

By:

Sulzer, David;
Cassidy, Clifford;
Horga, Guillermo;
Kang, Un Jung;
Fahn, Stanley;
Casella, Luigi;
Pezzoli, Gianni;
Langley, Jason;
Hu, Xiaoping P.;
Zucca, Fabio A.;
Isaias, Ioannis U.;
Zecca, Luigi

Publication type:

Article

The TCR repertoire of α-synuclein-specific T cells in Parkinson's disease is surprisingly diverse.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-79726-9

By:

Singhania, Akul;
Pham, John;
Dhanwani, Rekha;
Frazier, April;
Rezende Dutra, Juliana;
Marder, Karen S.;
Phillips, Elizabeth;
Mallal, Simon;
Amara, Amy W.;
Standaert, David G.;
Sulzer, David;
Peters, Bjoern;
Sette, Alessandro;
Lindestam Arlehamn, Cecilia S.

Publication type:

Article