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Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma.
Published in:
PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0057015
By:
- Manu, Kanjoormana Aryan;
- Shanmugam, Muthu K.;
- Ong, Tina H.;
- Subramaniam, Aruljothi;
- Siveen, Kodappully Sivaraman;
- Perumal, Ekambaram;
- Samy, Ramar Perumal;
- Bist, Pradeep;
- Lim, Lina H. K.;
- Kumar, Alan Prem;
- Hui, Kam M.;
- Sethi, Gautam
Publication type:
Article
Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3.
Published in:
British Journal of Pharmacology, 2013, v. 170, n. 4, p. 807, doi. 10.1111/bph.12302
By:
- Subramaniam, Aruljothi;
- Shanmugam, Muthu K;
- Ong, Tina H;
- Li, Feng;
- Perumal, Ekambaram;
- Chen, Luxi;
- Vali, Shireen;
- Abbasi, Taher;
- Kapoor, Shweta;
- Ahn, Kwang Seok;
- Kumar, Alan Prem;
- Hui, Kam M;
- Sethi, Gautam
Publication type:
Article
An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins.
Published in:
Apoptosis, 2013, v. 18, n. 10, p. 1175, doi. 10.1007/s10495-013-0851-5
By:
- Subramaniam, Aruljothi;
- Loo, Ser;
- Rajendran, Peramaiyan;
- Manu, Kanjoormana;
- Perumal, Ekambaram;
- Li, Feng;
- Shanmugam, Muthu;
- Siveen, Kodappully;
- Park, Joo-In;
- Ahn, Kwang;
- Hui, Kam;
- Kumar, Alan;
- Sethi, Gautam
Publication type:
Article
Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways.
Published in:
Apoptosis, 2011, v. 16, n. 10, p. 1, doi. 10.1007/s10495-011-0629-6
By:
- Kannaiyan, Radhamani;
- Manu, Kanjoormana Aryan;
- Chen, Luxi;
- Li, Feng;
- Rajendran, Peramaiyan;
- Subramaniam, Aruljothi;
- Lam, Paula;
- Kumar, Alan Prem;
- Sethi, Gautam
Publication type:
Article

Found: 4

Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma.

Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3.

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins.

Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways.