Works matching AU Sturis, Jeppe

Results: 38

GLP-1 derivative liraglutide in rats with Β-cell deficiencies: influence of metabolic state on Β cell dynamics.

Published in:

British Journal of Pharmacology, 2003, v. 140, n. 1, p. 123, doi. 10.1038/sj.bjp.0705397

By:

Sturis, Jeppe;
Gotfredsen, Carsten F.;
Romer, John;
Rolin, Bidda;
Ribel, Ulla;
Brand, Christian L.;
Wilken, Michael;
Wassermann, Karsten;
Deacon, Carolyn F.;
Carr, Richard D.;
Knudsen, Lotte Bjerre

Publication type:

Article

Enhanced disulphide bond stability contributes to the once-weekly profile of insulin icodec.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50477-9

By:

Hubálek, František;
Cramer, Christian N.;
Helleberg, Hans;
Johansson, Eva;
Nishimura, Erica;
Schluckebier, Gerd;
Steensgaard, Dorte Bjerre;
Sturis, Jeppe;
Kjeldsen, Thomas B.

Publication type:

Article

CHAOS AND CHAOTIC TRANSIENTS IN A FORCED MODEL OF THE ECONOMIC LONG WAVE: THE ROLE OF HOMOCLINIC BIFURCATION TO INFINITY.

Published in:

International Journal of Bifurcation & Chaos in Applied Sciences & Engineering, 1995, v. 5, n. 3, p. 741, doi. 10.1142/S0218127495000557

By:

STURIS, JEPPE;
BRØNS, MORTEN

Publication type:

Article

HOMOCLINIC BIFURCATION TO INFINITY IN A MODEL OF THE ECONOMIC LONG WAVE.

Published in:

International Journal of Bifurcation & Chaos in Applied Sciences & Engineering, 1992, v. 2, n. 1, p. 129, doi. 10.1142/S0218127492000124

By:

BRØNS, MORTEN;
STURIS, JEPPE

Publication type:

Article

Pharmacokinetics, pharmacodynamics, safety, and tolerability of a single-dose of NN2211, a long-acting glucagon-like peptide 1 derivative, in healthy male subjects.

Published in:

2002

By:

Elbrønd, Bodil;
Jakobsen, Grethe;
Larsen, Søren;
Agersø, Henrik;
Jensen, Lisbeth Bjerring;
Rolan, Paul;
Sturis, Jeppe;
Hatorp, Vibeke;
Zdravkovic, Milan;
Elbrønd, Bodil;
Larsen, Søren;
Agersø, Henrik

Publication type:

journal article

Repaglinide acutely amplifies pulsatile insulin secretion by augmentation of burst mass with no effect on burst frequency.

Published in:

2000

By:

Juhl, Claus B.;
Porksen, Niels;
Hollingdal, Malene;
Sturis, Jeppe;
Pincus, Steven;
Veldhuis, Johannes D.;
Dejgaard, Anders;
Schmitz, Ole;
Juhl, C B;
Pørksen, N;
Hollingdal, M;
Sturis, J;
Pincus, S;
Veldhuis, J D;
Dejgaard, A;
Schmitz, O

Publication type:

journal article

Alterations in the Patterns of Insulin Secretion Before and After Diagnosis of IDDM.

Published in:

Diabetes Care, 1995, v. 18, n. 4, p. 568, doi. 10.2337/diacare.18.4.568

By:

O'Meara, Niall M.;
Sturis, Jeppe;
Herold, Kevan C.;
Ostrega, Diane M.;
Polonsky, Kenneth S.

Publication type:

Article

Hopf bifurcation analysis applied to predator-prey modeling.

Published in:

System Dynamics Review (Wiley), 1992, v. 8, n. 2, p. 179, doi. 10.1002/sdr.4260080206

By:

Gross, Peter;
Sturis, Jeppe

Publication type:

Article

Local and global bifurcations in a model of the economic long wave.

Published in:

System Dynamics Review (Wiley), 1991, v. 7, n. 1, p. 41, doi. 10.1002/sdr.4260070104

By:

Brøns, Morten;
Sturis, Jeppe

Publication type:

Article

Bifurcation sequence in a simple model of migratory dynamics.

Published in:

System Dynamics Review (Wiley), 1988, v. 4, n. 1/2, p. 208, doi. 10.1002/sdr.4260040112

By:

Sturis, Jeppe;
Mosekilde, Erik

Publication type:

Article

Chaotic structures in generic management models: Pedagogical principles and examples.

Published in:

System Dynamics Review (Wiley), 1988, v. 4, n. 1/2, p. 218, doi. 10.1002/sdr.4260040113

By:

Andersen, David F.;
Sturis, Jeppe

Publication type:

Article

Elucidating the Mechanism of Absorption of Fast-Acting Insulin Aspart: The Role of Niacinamide.

Published in:

Pharmaceutical Research, 2019, v. 36, n. 3, p. 1, doi. 10.1007/s11095-019-2578-7

By:

Kildegaard, Jonas;
Buckley, Stephen T.;
Nielsen, Rasmus H.;
Povlsen, Gro K.;
Seested, Torben;
Ribel, Ulla;
Olsen, Helle B.;
Ludvigsen, Svend;
Jeppesen, Claus B.;
Refsgaard, Hanne H. F.;
Bendtsen, Kristian M.;
Kristensen, Niels R.;
Hostrup, Susanne;
Sturis, Jeppe

Publication type:

Article

Effects of Metformin on Insulin Secretion, Insulin Action, and Ovarian Steroidogenesis in Women with Polycystic Ovary Syndrome*.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1997, v. 82, n. 2, p. 524, doi. 10.1210/jcem.82.2.3722

By:

EHRMANN, DAVID A.;
CAVAGHAN, MELISSA K.;
IMPERIAL, JACQUELINE;
STURIS, JEPPE;
ROSENFIELD, ROBERT L.;
POLONSKY, KENNETH S.

Publication type:

Article

Probing the mechanism of reduced in vivo potency of insulin detemir.

Published in:

Expert Opinion on Drug Metabolism & Toxicology, 2023, v. 19, n. 4, p. 225, doi. 10.1080/17425255.2023.2219389

By:

Brand, Christian Lehn;
Sturis, Jeppe

Publication type:

Article

Pharmacological Inhibition of Hormone Sensitive Lipase (HSL) Improves Lipid and Glucose Homeostasis in the Obese Zucker Rat.

Published in:

Diabetes, 2007, v. 56, p. A357

By:

Fledelius, Christian;
Vinterby, Aase;
Damgaard, Jesper;
De Jong, Johannes C.;
Sturis, Jeppe;
Jacobsen, Poul

Publication type:

Article

Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islets.

Published in:

2004

By:

Maedler, Kathrin;
Størling, Joachim;
Sturis, Jeppe;
Zuellig, Richard A;
Spinas, Giatgen A;
Arkhammar, Per O G;
Mandrup-Poulsen, Thomas;
Donath, Marc Y

Publication type:

journal article

Glucose- and Interleukin-1β- Induced β-Cell Apoptosis Requires Ca2+ Influx and Extracellular Signal-Regulated Kinase (ERK) ½ Activation and Is Prevented by a Sulfonylurea Receptor 1/Inwardly Rectifying K+ Channel 6.2 (SUR/Kir6.2) Selective Potassium Channel Opener in Human Islets

Published in:

Diabetes, 2004, v. 53, n. 7, p. 1706, doi. 10.2337/diabetes.53.7.1706

By:

Maedler, Kathrin;
Zuellig, Richard A.;
Spinas, Giatgen A.;
Donath, Marc Y.;
Sterling, Joachim;
Sturis, Jeppe;
Arkhammar, Per O. G.;
Mandrup-Poulsen, Thomas

Publication type:

Article

One week's treatment with the long-acting glucagon-like peptide 1 derivative liraglutide (NN2211) markedly improves 24-h glycemia and alpha- and beta-cell function and reduces endogenous glucose release in patients with type 2 diabetes.

Published in:

2004

By:

Degn, Kristine B.;
Juhl, Claus B.;
Sturis, Jeppe;
Jakobsen, Grethe;
Brock, Birgitte;
Chandramouli, Visvanathan;
Rungby, Joergen;
Landau, Bernard R.;
Schmitz, Ole

Publication type:

journal article

Improved beta-cell survival and reduced insulitis in a type 1 diabetic rat model after treatment with a beta-cell-selective K(ATP) channel opener.

Published in:

2004

By:

Skak, Kresten;
Gotfredsen, Carsten F;
Lundsgaard, Dorthe;
Hansen, John Bondo;
Sturis, Jeppe;
Markholst, Helle

Publication type:

journal article

Improved β-Cell Survival and Reduced Insulitis in a Type 1 Diabetic Rat Model After Treatment With a β-Cell-Selective K ATP Channel Opener.

Published in:

Diabetes, 2004, v. 53, n. 4, p. 1089, doi. 10.2337/diabetes.53.4.1089

By:

Skak, Kresten;
Gotfredsen, Carsten F.;
Lundsgaard, Dorthe;
Hansen, John Bondo;
Sturis, Jeppe;
Markholst, Helle

Publication type:

Article

NN414, a SUR1/Kir6.2-selective potassium channel opener, reduces blood glucose and improves glucose tolerance in the VDF Zucker rat.

Published in:

2003

By:

Carr, Richard D.;
Brand, Christian L.;
Bodvarsdottir, Thora B.;
Hansen, John B.;
Sturis, Jeppe

Publication type:

journal article

The GLP-1 derivative NN2211 restores beta-cell sensitivity to glucose in type 2 diabetic patients after a single dose.

Published in:

2003

By:

Chang, Annette M;
Jakobsen, Grethe;
Sturis, Jeppe;
Smith, Marla J;
Bloem, Cathie J;
An, Bob;
Galecki, Andrzej;
Halter, Jeffrey B

Publication type:

journal article

The GLP-1 Derivative NN2211 Restores β-Cell Sensitivity to Glucose in Type 2 Diabetic Patients After a Single Dose.

Published in:

Diabetes, 2003, v. 52, n. 7, p. 1786, doi. 10.2337/diabetes.52.7.1786

By:

Chang, Annette M.;
Jakobsen, Grethe;
Sturis, Jeppe;
Smith, Marla J.;
Bloem, Cathie J.;
An, Bob;
Galecki, Andrzej;
Halter, Jeffrey B.

Publication type:

Article

Bedtime administration of NN2211, a long-acting GLP-1 derivative, substantially reduces fasting and postprandial glycemia in type 2 diabetes.

Published in:

2002

By:

Juhl, Claus B.;
Hollingdal, Malene;
Sturis, Jeppe;
Jakobsen, Grethe;
Agerso, Henrik;
Veldhuis, Johannes;
Porksen, Niels;
Schmitz, Ole;
Agersø, Henrik;
Pørksen, Niels

Publication type:

journal article

Failure of physiological plasma glucose excursions to entrain high-frequency pulsatile insulin secretion in type 2 diabetes.

Published in:

2000

By:

Hollingdal, Malene;
Juhl, Claus B.;
Pincus, Steven M.;
Sturis, Jeppe;
Veldhuis, Johannes D.;
Polonsky, Kenneth S.;
Porksen, Niels;
Schmitz, Ole;
Hollingdal, M;
Juhl, C B;
Pincus, S M;
Sturis, J;
Veldhuis, J D;
Polonsky, K S;
Pørksen, N;
Schmitz, O

Publication type:

journal article

Changes in pancreatic islet glucokinase and hexokinase activities with increasing age, obesity, and the onset of diabetes.

Published in:

1997

By:

Cockburn, Brian N.;
Ostrega, Diane M.;
Sturis, Jeppe;
Kubstrup, Christian;
Polonsky, Kenneth S.;
Bell, Graeme I.;
Cockburn, B N;
Ostrega, D M;
Sturis, J;
Kubstrup, C;
Polonsky, K S;
Bell, G I

Publication type:

journal article

Altered Insulin Secretory Responses to Glucose in Diabetic and Nondiabetic Subjects With Mutations in the Diabetes Susceptibility Gene MODY3 on Chromosome 12.

Published in:

Diabetes, 1996, v. 45, n. 11, p. 1503, doi. 10.2337/diab.45.11.1503

By:

Byrne, Maria M.;
Sturis, Jeppe;
Menzel, Stephan;
Yamagata, Kazuya;
Fajans, Stefan S.;
Dronsfield, Mark J.;
Bain, Stephen C.;
Hattersley, Andrew T.;
Velho, Gilberto;
Froguel, Phillipe;
Bell, Graeme I.;
Polonsky, Kenneth S.

Publication type:

Article

Clinical phenotypes, insulin secretion, and insulin sensitivity in kindreds with maternally inherited diabetes and deafness due to mitochondrial tRNALeu(UUR) gene mutation.

Published in:

1996

By:

Velho, Gilberto;
Byrne, Maria M.;
Clément, Karine;
Sturis, Jeppe;
Pueyo, Maria E.;
Blanché, Hèlene;
Vionnet, Nathalie;
Fiet, Jean;
Passa, Philippe;
Robert, Jean-Jacques;
Polonsky, Kenneth S.;
Froguel, Philippe;
Velho, G;
Byrne, M M;
Clément, K;
Sturis, J;
Pueyo, M E;
Blanché, H;
Vionnet, N;
Fiet, J

Publication type:

journal article

Evolution of β-Cell Dysfunction in the Male Zucker Diabetic Fatty Rat.

Published in:

Diabetes, 1995, v. 44, n. 12, p. 1447, doi. 10.2337/diab.44.12.1447

By:

Tokuyama, Yoshiharu;
Sturis, Jeppe;
DePaoli, Alex M.;
Takeda, Jun;
Stoffel, Markus;
Jiping Tang;
Xiaohong Sun;
Polonsky, Kenneth S.;
Bell, Graeme I.

Publication type:

Article

Comparison of the pharmacokinetics of three concentrations of insulin aspart during continuous subcutaneous insulin infusion ( CSII) in a pig model.

Published in:

Journal of Pharmacy & Pharmacology, 2013, v. 65, n. 2, p. 230, doi. 10.1111/j.2042-7158.2012.01596.x

By:

Petersen, Signe Beck;
Nielsen, Flemming Seier;
Ribel, Ulla;
Sturis, Jeppe;
Skyggebjerg, Ole

Publication type:

Article

Altered insulin secretory responses to glucose in subjects with a mutation in the MODY1 gene on chromosome 20.

Published in:

1995

By:

Byrne, Maria M.;
Sturis, Jeppe;
Fajans, Stefan S.;
Ortiz, F. Javier;
Stoltz, Anjanette;
Stoffel, Markus;
Smith, Marla J.;
Bell, Graeme I.;
Halter, Jeffrey B.;
Polonsky, Kenneth S.;
Byrne, M M;
Sturis, J;
Fajans, S S;
Ortiz, F J;
Stoltz, A;
Stoffel, M;
Smith, M J;
Bell, G I;
Halter, J B;
Polonsky, K S

Publication type:

journal article

Defects in insulin secretion and action in women with a history of gestational diabetes.

Published in:

1995

By:

Ryan, Edmond A.;
Imes, Sharleen;
Dating Liu;
McManus, Ruth;
Finegood, Diane T.;
Polonsky, Kenneth S.;
Sturis, Jeppe;
Ryan, E A;
Imes, S;
Liu, D;
McManus, R;
Finegood, D T;
Polonsky, K S;
Sturis, J

Publication type:

journal article

Compensation in Pancreatic β-Cell Function in Subjects With Glucokinase Mutations.

Published in:

Diabetes, 1994, v. 43, n. 5, p. 718, doi. 10.2337/diab.43.5.718

By:

Sturis, Jeppe;
Kurland, Irwin J.;
Byrne, Maria M.;
Mosekilde, Erik;
Froguel, Philippe;
Pilkis, Simon J.;
Bell, Graeme I.;
Polonsky, Kenneth S.

Publication type:

Article

Abnormal insulin secretion, not insulin resistance, is the genetic or primary defect of MODY in the RW pedigree.

Published in:

1994

By:

Herman, William H.;
Fajans, Stefan S.;
Ortiz, Francisco J.;
Smith, Marla J.;
Sturis, Jeppe;
Bell, Graeme I.;
Polonsky, Kenneth S.;
Halter, Jeffrey B.;
Herman, W H;
Fajans, S S;
Ortiz, F J;
Smith, M J;
Sturis, J;
Bell, G I;
Polonsky, K S;
Halter, J B

Publication type:

journal article

Oscillatory insulin secretion after pancreas transplant.

Published in:

1993

By:

O'Meara, Niall M.;
Sturis, Jeppe;
Blackman, John D.;
Byrne, Maria M.;
Jaspan, Jonathan B.;
Roland, Dianne C.;
Thistlethwaite, J. Richard;
Polonsky, Kenneth S.;
O'Meara, N M;
Sturis, J;
Blackman, J D;
Byrne, M M;
Jaspan, J B;
Roland, D C;
Thistlethwaite, J R;
Polonsky, K S

Publication type:

journal article

Insulin secretory profiles and C-peptide clearance kinetics at 6 months and 2 years after kidney-pancreas transplantation.

Published in:

1992

By:

Blackman, John D.;
Polonsky, Kenneth S.;
Jaspan, Jonathan B.;
Sturis, Jeppe;
Van Cauter, Eve;
Thistlethwaite, J. Richard;
Blackman, J D;
Polonsky, K S;
Jaspan, J B;
Sturis, J;
Van Cauter, E;
Thistlethwaite, J R

Publication type:

journal article

Hypoglycemic thresholds for cognitive dysfunction in IDDM.

Published in:

1992

By:

Blackman, John D.;
Towle, Vernon L.;
Sturis, Jeppe;
Lewis, Gary F.;
Spire, Jean-Paul;
Polonsky, Kenneth S.;
Blackman, J D;
Towle, V L;
Sturis, J;
Lewis, G F;
Spire, J P;
Polonsky, K S

Publication type:

journal article

Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance.

Published in:

1992

By:

Van Cauter, Eve;
Mestrez, Fabienne;
Sturis, Jeppe;
Polonsky, Kenneth S.;
Van Cauter, E;
Mestrez, F;
Sturis, J;
Polonsky, K S

Publication type:

journal article