Works by Stuehr, Dennis

Results: 38

Inducible nitric oxide synthase: role of the N-terminal ß-hairpin hook and pterin-binding segment in dimerization and tetrahydrobiopterin interaction.

Published in:

EMBO Journal, 1999, v. 18, n. 22, p. 6260, doi. 10.1093/emboj/18.22.6260

By:

Ghosh, Dipak K.;
Crane, Brian R.;
Ghosh, Sanjay;
Wolan, Dennis;
Gachhui, Ratan;
Crooks, Carol;
Presta, Anthony;
Tainer, John A.;
Getzoff, Elizabeth D.;
Stuehr, Dennis J.

Publication type:

Article

N-terminal domain swapping and metal ion binding in nitric oxide synthase dimerization.

Published in:

EMBO Journal, 1999, v. 18, n. 22, p. 6271, doi. 10.1093/emboj/18.22.6271

By:

Crane, Brian R.;
Rosenfeld, Robin J.;
Arvai, Andrew S.;
Ghosh, Dipak K.;
Ghosh, Sanjav;
Tainer, John A.;
Stuehr, Dennis J.;
Getzoff, Elizabeth D.

Publication type:

Article

Regional variations in allergen‐induced airway inflammation correspond to changes in soluble guanylyl cyclase heme and expression of heme oxygenase‐1.

Published in:

FASEB Journal, 2024, v. 38, n. 6, p. 1, doi. 10.1096/fj.202301626RRR

By:

Sumi, Mamta P.;
Westcott, Rosemary;
Stuehr, Eric;
Ghosh, Chaitali;
Stuehr, Dennis J.;
Ghosh, Arnab

Publication type:

Article

GAPDH is involved in the heme-maturation of myoglobin and hemoglobin.

Published in:

FASEB Journal, 2022, v. 36, n. 2, p. 1, doi. 10.1096/fj.202101237RR

By:

Tupta, Blair;
Stuehr, Eric;
Sumi, Mamta P.;
Sweeny, Elizabeth A.;
Smith, Brandon;
Stuehr, Dennis J.;
Ghosh, Arnab

Publication type:

Article

Soluble Guanylate Cyclase Agonists Induce Bronchodilation in Human Small Airways.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2020, v. 62, n. 1, p. 43, doi. 10.1165/rcmb.2019-0001OC

By:

Koziol-White, Cynthia J.;
Ghosh, Arnab;
Sandner, Peter;
Erzurum, Serpil E.;
Stuehr, Dennis J.;
Panettieri Jr., Reynold A.

Publication type:

Article

Soluble Guanylate Cyclase Agonists Induce Bronchodilation in Human Small Airways.

Published in:

2020

By:

Koziol-White, Cynthia J.;
Ghosh, Arnab;
Sandner, Peter;
Erzurum, Serpil E.;
Stuehr, Dennis J.;
Panettieri Jr., Reynold A.

Publication type:

Chart/Diagram/Graph

Excretory/secretory products from plerocercoids of Spirometra erinacei reduce iNOS and chemokine mRNA levels in peritoneal macrophages stimulated with cytokines and/or LPS.

Published in:

Parasite Immunology, 1997, v. 19, n. 7, p. 325, doi. 10.1046/j.1365-3024.1997.d01-215.x

By:

FUKUMOTO, SOJI;
HIRAI, KAZUMITSU;
TANIHATA, TAKEO;
OHMORI, YOSHIHIRO;
STUEHR, DENNIS J.;
HAMILTON, THOMAS A.

Publication type:

Article

A natural heme deficiency exists in biology that allows nitric oxide to control heme protein functions by regulating cellular heme distribution.

Published in:

BioEssays, 2023, v. 45, n. 8, p. 1, doi. 10.1002/bies.202300055

By:

Stuehr, Dennis J.;
Biswas, Pranjal;
Dai, Yue;
Ghosh, Arnab;
Islam, Sidra;
Jayaram, Dhanya Thamaraparambil

Publication type:

Article

Thermodynamic characterization of five key kinetic parameters that define neuronal nitric oxide synthase catalysis.

Published in:

FEBS Journal, 2013, v. 280, n. 18, p. 4439, doi. 10.1111/febs.12404

By:

Haque, Mohammad Mahfuzul;
Tejero, Jesús;
Bayachou, Mekki;
Wang, Zhi ‐ Qiang;
Fadlalla, Mohammed;
Stuehr, Dennis J.

Publication type:

Article

A kinetic model linking protein conformational motions, interflavin electron transfer and electron flux through a dual-flavin enzyme - simulating the reductase activity of the endothelial and neuronal nitric oxide synthase flavoprotein domains.

Published in:

FEBS Journal, 2011, v. 278, n. 21, p. 4055, doi. 10.1111/j.1742-4658.2011.08310.x

By:

Haque, Mohammad M.;
Kenney, Claire;
Tejero, Jesús;
Stuehr, Dennis J.

Publication type:

Article

NO synthase isoforms specifically modify peroxynitrite reactivity.

Published in:

FEBS Journal, 2010, v. 277, n. 19, p. 3963, doi. 10.1111/j.1742-4658.2010.07786.x

By:

Maréchal, Amandine;
Mattioli, Tony A.;
Stuehr, Dennis J.;
Santolini, Jérôme

Publication type:

Article

Fast ferrous heme–NO oxidation in nitric oxide synthases.

Published in:

FEBS Journal, 2009, v. 276, n. 16, p. 4505, doi. 10.1111/j.1742-4658.2009.07157.x

By:

Tejero, Jesús;
Santolini, Jérôme;
Stuehr, Dennis J.

Publication type:

Article

Structural and mechanistic aspects of flavoproteins: electron transfer through the nitric oxide synthase flavoprotein domain.

Published in:

FEBS Journal, 2009, v. 276, n. 15, p. 3959, doi. 10.1111/j.1742-4658.2009.07120.x

By:

Stuehr, Dennis J.;
Tejero, Jesús;
Haque, Mohammad M.

Publication type:

Article

Reactivity of the heme–dioxygen complex of the inducible nitric oxide synthase in the presence of alternative substrates.

Published in:

FEBS Journal, 2006, v. 273, n. 1, p. 180, doi. 10.1111/j.1742-4658.2005.05056.x

By:

Lefèvre-Groboillot, David;
Boucher, Jean-Luc;
Mansuy, Daniel;
Stuehr, Dennis J.

Publication type:

Article

Relationship between the structure of guanidines and N-hydroxyguanidines, their binding to inducible nitric oxide synthase (iNOS) and their iNOS-catalysed oxidation to NO.

Published in:

FEBS Journal, 2005, v. 272, n. 12, p. 3172, doi. 10.1111/j.1742-4658.2005.04736.x

By:

Lefèvre-Groboillot, David;
Boucher, Jean-Luc;
Stuehr, Dennis J.;
Mansuy, Daniel

Publication type:

Article

Heme delivery to heme oxygenase-2 involves glyceraldehyde-3-phosphate dehydrogenase.

Published in:

Biological Chemistry, 2022, v. 403, n. 11/12, p. 1043, doi. 10.1515/hsz-2022-0230

By:

Dai, Yue;
Fleischhacker, Angela S.;
Liu, Liu;
Fayad, Sara;
Gunawan, Amanda L.;
Stuehr, Dennis J.;
Ragsdale, Stephen W.

Publication type:

Article

New roles for GAPDH, Hsp90, and NO in regulating heme allocation and hemeprotein function in mammals.

Published in:

Biological Chemistry, 2022, v. 403, n. 11/12, p. 1005, doi. 10.1515/hsz-2022-0197

By:

Stuehr, Dennis J.;
Dai, Yue;
Biswas, Pranjal;
Sweeny, Elizabeth A.;
Ghosh, Arnab

Publication type:

Article

14-3-3 in Thoracic Aortic Aneurysms: Identification of a Novel Autoantigen in Large Vessel Vasculitis.

Published in:

Arthritis & Rheumatology, 2015, v. 67, n. 7, p. 1913, doi. 10.1002/art.39130

By:

Chakravarti, Ritu;
Gupta, Karishma;
Swain, Mamuni;
Willard, Belinda;
Scholtz, Jaclyn;
Svensson, Lars G.;
Roselli, Eric E.;
Pettersson, Gosta;
Johnston, Douglas R.;
Soltesz, Edward G.;
Yamashita, Michifumi;
Stuehr, Dennis;
Daly, Thomas M.;
Hoffman, Gary S.

Publication type:

Article

Inactivation of soluble guanylyl cyclase in living cells proceeds without loss of haem and involves heterodimer dissociation as a common step.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 11, p. 2505, doi. 10.1111/bph.15527

By:

Dai, Yue;
Stuehr, Dennis J.

Publication type:

Article

Nitric oxide synthase enzymology in the 20 years after the Nobel Prize.

Published in:

2019

By:

Stuehr, Dennis J;
Haque, Mohammad Mahfuzul

Publication type:

journal article

Abnormalities in nitric oxide and its derivatives in lung cancer.

Published in:

2005

By:

Masri, Fares A.;
Comhair, Suzy A. A.;
Koeck, Thomas;
Weiling Xu;
Janocha, Allison;
Ghosh, Sudakshina;
Dweik, Raed A.;
Golish, Joseph;
Kinter, Michael;
Stuehr, Dennis J.;
Erzurum, Serpil C.;
Aulak, Kulwant S.;
Xu, Weiling

Publication type:

journal article

Mechanisms driving heme insertion into apo-sGC during its maturation in cells.

Published in:

2013

By:

Stuehr, Dennis;
Ghosh, Arnab;
Sarkar, Anindya;
Dai, Yue

Publication type:

Abstract

Tyk2 Tyrosine Kinase Expression Is Required for the Maintenance of Mitochondrial Respiration in Primary Pro-B Lymphocytes.

Published in:

Molecular & Cellular Biology, 2006, v. 26, n. 22, p. 30, doi. 10.1128/MCB.00497-06

By:

Potla, Ramesh;
Koeck, Thomas;
Wegrzyn, Joanna;
Cherukuri, Srujana;
Shimoda, Kazuya;
Baker, Darren P.;
Wolfman, Janice;
Planchon, Sarah M.;
Esposito, Christine;
Hoit, Brian;
Dulak, Jozef;
Wolfman, Alan;
Stuehr, Dennis;
Larner, Andrew C.

Publication type:

Article

Does Endothelium-Derived Nitric Oxide Have a Rolein Cytokine-Induced Hypotension?

Published in:

JNCI: Journal of the National Cancer Institute, 1990, v. 82, n. 9, p. 726

By:

Nathan, Carl F.;
Stuehr, Dennis J.

Publication type:

Article

Nitric oxide alters hyaluronan deposition by airway smooth muscle cells.

Published in:

PLoS ONE, 2018, v. 13, n. 7, p. 1, doi. 10.1371/journal.pone.0200074

By:

Majors, Alana K.;
Chakravarti, Ritu;
Ruple, Lisa M.;
Leahy, Rachel;
Stuehr, Dennis J.;
Lauer, Mark;
Erzurum, Serpil C.;
Janocha, Allison;
Aronica, Mark A.

Publication type:

Article

The exchanged EF-hands in calmodulin and troponin C chimeras impair the Ca<sup>2+</sup>-induced hydrophobicity and alter the interaction with Orai1: a spectroscopic, thermodynamic and kinetic study.

Published in:

BMC Biochemistry, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12858-015-0036-7

By:

Jensen, Drake;
Reynolds, Nicole;
Ya-Ping Yang;
Shubha Shakya;
Zhi-Qiang Wang;
Stuehr, Dennis J.;
Chin-Chuan Wei

Publication type:

Article

Myoglobin maturation is driven by the hsp90 chaperone machinery and by soluble guanylyl cyclase.

Published in:

FASEB Journal, 2019, v. 33, n. 9, p. 9885, doi. 10.1096/fj.201802793RR

By:

Ghosh, Arnab;
Yue Dai;
Biswas, Pranjal;
Stuehr, Dennis J.

Publication type:

Article

Pick a ska or reggae beat? Rates of conformational switching in multi‐domain flavoproteins and their relationship to electron flux through the enzymes (768.8).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.768.8

By:

Haque, Mohammad;
Bayachou, Mekki;
Im, Sang‐Choul;
Pearl, May;
Waskell, Lucy;
Stuehr, Dennis

Publication type:

Article

Green Tea Polyphenols Decrease Enzyme Activity of Nitric Oxide Synthase.

Published in:

FASEB Journal, 2013, v. 27, p. 790.14, doi. 10.1096/fasebj.27.1_supplement.790.14

By:

Wang, Zhiqiang Molly;
Tidrick, Conner L;
Haque, Mahfuzul;
Stuehr, Dennis J.

Publication type:

Article

Hsp90 interacts with inducible NO synthase client protein in its heme-free state and then drives heme insertion by an ATP-dependent process.

Published in:

FASEB Journal, 2011, v. 25, n. 6, p. 2049, doi. 10.1096/fj.10-180554

By:

Ghosh, Arnab;
Chawla-Sarkar, Mamta;
Stuehr, Dennis J.

Publication type:

Article

Dissecting structural and electronic effects in inducible nitric oxide synthase.

Published in:

Biochemical Journal, 2015, v. 467, n. 1, p. 153, doi. 10.1042/BJ20141319

By:

Hannibal, Luciana;
Page, Richard C.;
Haque, Mohammad Mahfuzul;
Bolisetty, Karthik;
Zhihao Yu;
Misra, Saurav;
Stuehr, Dennis J.

Publication type:

Article

Charge-pairing interactions control the conformational setpoint and motions of the FMN domain in neuronal nitric oxide synthase.

Published in:

Biochemical Journal, 2013, v. 450, n. 3, p. 607, doi. 10.1042/BJ20121488

By:

HAQUE, Mohammad Mahfuzul;
BAYACHOU, Mekki;
FADLALLA, Mohammed A.;
DURRA, Deborah;
STUEHR, Dennis J.

Publication type:

Article

Tetrahydrobiopterin in nitric oxide synthase.

Published in:

IUBMB Life, 2013, v. 65, n. 4, p. 358, doi. 10.1002/iub.1136

By:

Tejero, Jesús;
Stuehr, Dennis

Publication type:

Article

Occurrence, structure, and evolution of nitric oxide synthase-like proteins in the plant kingdom.

Published in:

Science Signaling, 2016, v. 9, n. 417, p. 1, doi. 10.1126/scisignal.aad4403

By:

Jeandroz, Sylvain;
Wipf, Daniel;
Stuehr, Dennis J.;
Lamattina, Lorenzo;
Melkonian, Michael;
Zhijian Tian;
Ying Zhu;
Carpenter, Eric J.;
Gane Ka-Shu Wong;
Wendehenne, David

Publication type:

Article

Metal binding and conformational studies of the calcium binding domain of NADPH oxidase 5 reveal its similarity and difference to calmodulin.

Published in:

Journal of Biomolecular Structure & Dynamics, 2020, v. 38, n. 8, p. 2352, doi. 10.1080/07391102.2019.1633409

By:

Wei, Chin-Chuan;
Fabry, Emily;
Hay, Evan;
Lloyd, Laura;
Kaufman, Nichole;
Yang, Ya-Ping;
Stuehr, Dennis J.

Publication type:

Article

Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.

Published in:

Nature Chemical Biology, 2008, v. 4, n. 11, p. 700, doi. 10.1038/nchembio.115

By:

Garcin, Elsa D.;
Arvai, Andrew S.;
Rosenfeld, Robin J.;
Kroeger, Matt D.;
Crane, Brian R.;
Andersson, Gunilla;
Andrews, Glen;
Hamley, Peter J.;
Mallinder, Philip R.;
Nicholls, David J.;
St-Gallay, Stephen A.;
Tinker, Alan C.;
Gensmantel, Nigel P.;
Mete, Antonio;
Cheshire, David R.;
Connolly, Stephen;
Stuehr, Dennis J.;
Åberg, Anders;
Wallace, Alan V.;
Tainer, John A.

Publication type:

Article

Tetrahydrobiopterin redox cycling in nitric oxide synthase: evidence supports a through-heme electron delivery.

Published in:

FEBS Journal, 2016, v. 283, n. 24, p. 4491, doi. 10.1111/febs.13933

By:

Ramasamy, Somasundaram;
Haque, Mohammad Mahfuzul;
Gangoda, Mahinda;
Stuehr, Dennis J.

Publication type:

Article

Distinct conformational behaviors of four mammalian dual-flavin reductases (cytochrome P450 reductase, methionine synthase reductase, neuronal nitric oxide synthase, endothelial nitric oxide synthase) determine their unique catalytic profiles.

Published in:

FEBS Journal, 2014, v. 281, n. 23, p. 5325, doi. 10.1111/febs.13073

By:

Haque, Mohammad M.;
Bayachou, Mekki;
Tejero, Jesus;
Kenney, Claire T.;
Pearl, Naw M.;
Im, Sang‐Choul;
Waskell, Lucy;
Stuehr, Dennis J.

Publication type:

Article