Works matching AU Studer, Lorenz

Results: 74

Derivation of Multipotent Mesenchymal Precursors from Human Embryonic Stem Cells.

Published in:

PLoS Medicine, 2005, v. 2, n. 6, p. 0554, doi. 10.1371/journal.pmed.0020161

By:

Barberi, Tiziano;
Willis, Lucy M.;
Socci, Nicholas D.;
Studer, Lorenz

Publication type:

Article

Pluripotent stem cells in regenerative medicine: challenges and recent progress.

Published in:

Nature Reviews Genetics, 2014, v. 15, n. 2, p. 82, doi. 10.1038/nrg3563

By:

Tabar, Viviane;
Studer, Lorenz

Publication type:

Article

Sustained Epigenetic Reactivation in Fragile X Neurons with an RNA-Binding Small Molecule.

Published in:

Genes, 2025, v. 16, n. 3, p. 278, doi. 10.3390/genes16030278

By:

Kam, Christina W.;
Dumelie, Jason G.;
Ciceri, Gabriele;
Yang, Wang-Yong;
Disney, Matthew D.;
Studer, Lorenz;
Jaffrey, Samie R.

Publication type:

Article

Therapeutic cloning in individual parkinsonian mice.

Published in:

Nature Medicine, 2008, v. 14, n. 4, p. 379, doi. 10.1038/nm1732

By:

Tabar, Viviane;
Tomishima, Mark;
Panagiotakos, Georgia;
Wakayama, Sayaka;
Menon, Jayanthi;
Chan, Bill;
Mizutani, Eiji;
Al-Shamy, George;
Ohta, Hiroshi;
Wakayama, Teruhiko;
Studer, Lorenz

Publication type:

Article

Derivation of engraftable skeletal myoblasts from human embryonic stem cells.

Published in:

Nature Medicine, 2007, v. 13, n. 5, p. 642, doi. 10.1038/nm1533

By:

Barberi, Tiziano;
Bradbury, Michelle;
Dincer, Zehra;
Panagiotakos, Georgia;
Socci, Nicholas D;
Studer, Lorenz

Publication type:

Article

The SATB1‐MIR22‐GBA axis mediates glucocerebroside accumulation inducing a cellular senescence‐like phenotype in dopaminergic neurons.

Published in:

Aging Cell, 2024, v. 23, n. 4, p. 1, doi. 10.1111/acel.14077

By:

Russo, Taylor;
Kolisnyk, Benjamin;
B. S., Aswathy;
Plessis‐Belair, Jonathan;
Kim, Tae Wan;
Martin, Jacqueline;
Ni, Jason;
Pearson, Jordan A.;
Park, Emily J.;
Sher, Roger B.;
Studer, Lorenz;
Riessland, Markus

Publication type:

Article

Reply to “Survival of expanded dopaminergic precursors is critical for clinical trials”.

Published in:

Nature Neuroscience, 1998, v. 1, n. 7, p. 537, doi. 10.1038/2774

By:

Studer, Lorenz;
Tabar, Viviane;
McKay, Ronald

Publication type:

Article

Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats.

Published in:

Nature Neuroscience, 1998, v. 1, n. 4, p. 290, doi. 10.1038/1105

By:

Studer, Lorenz;
Tabar, Viviane;
McKay, Ron

Publication type:

Article

Author Correction: Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia.

Published in:

2021

By:

Ajiro, Masahiko;
Awaya, Tomonari;
Kim, Young Jin;
Iida, Kei;
Denawa, Masatsugu;
Tanaka, Nobuo;
Kurosawa, Ryo;
Matsushima, Shingo;
Shibata, Saiko;
Sakamoto, Tetsunori;
Studer, Lorenz;
Krainer, Adrian R.;
Hagiwara, Masatoshi

Publication type:

Correction Notice

Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25326-8

By:

Diener, Johanna;
Baggiolini, Arianna;
Pernebrink, Mattias;
Dalcher, Damian;
Lerra, Luigi;
Cheng, Phil F.;
Varum, Sandra;
Häusel, Jessica;
Stierli, Salome;
Treier, Mathias;
Studer, Lorenz;
Basler, Konrad;
Levesque, Mitchell P.;
Dummer, Reinhard;
Santoro, Raffaella;
Cantù, Claudio;
Sommer, Lukas

Publication type:

Article

Targeting Homologous Recombination in Notch-Driven C. elegans Stem Cell and Human Tumors.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0127862

By:

Deng, Xinzhu;
Michaelson, David;
Tchieu, Jason;
Cheng, Jin;
Rothenstein, Diana;
Feldman, Regina;
Lee, Sang-gyu;
Fuller, John;
Haimovitz-Friedman, Adriana;
Studer, Lorenz;
Powell, Simon;
Fuks, Zvi;
Hubbard, E. Jane Albert;
Kolesnick, Richard

Publication type:

Article

ZFX Controls the Self-Renewal of Human Embryonic Stem Cells.

Published in:

PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0042302

By:

Harel, Sivan;
Tu, Edmund Y.;
Weisberg, Stuart;
Esquilin, Manuel;
Chambers, Stuart M.;
Liu, Becky;
Carson, Christian T.;
Studer, Lorenz;
Reizis, Boris;
Tomishima, Mark J.;
Wei-Chun Chin

Publication type:

Article

Maturation of Spinal Motor Neurons Derived from Human Embryonic Stem Cells.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0040154

By:

Takazawa, Tomonori;
Croft, Gist F.;
Amoroso, Mackenzie W.;
Studer, Lorenz;
Wichterle, Hynek;
MacDermott, Amy B.

Publication type:

Article

Enhanced In Vitro Midbrain Dopamine Neuron Differentiation, Dopaminergic Function, Neurite Outgrowth, and 1-Methyl-4-Phenylpyridium Resistance in Mouse Embryonic Stem Cells Overexpressing Bcl-XL.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 4, p. 843, doi. 10.1523/JNEUROSCI.3977-03.2004

By:

Jae-Won Shim, Edward R.;
Hyun-Chul Koh, Edward R.;
Mi-Yoon Chang;
Eun Roh, Edward R.;
Cha-Yong Choi;
Oh, Young J.;
Hyeon Son, Young J.;
Yong-Sung Lee;
Studer, Lorenz;
Sang-Hun Lee

Publication type:

Article

Acquisition of in vitro and in vivo functionality of Nurr1-induced dopamine neurons.

Published in:

FASEB Journal, 2006, v. 20, n. 14, p. 2553, doi. 10.1096/fj.06-6159fje

By:

Chang-Hwan Park;
Jin Sun Kang;
Yeon Ho Shin;
Mi-Yoon Chang;
Seungsoo Chung;
Hyun-Chul Koh;
Mei Hong Zhu;
Seog Bae Oh;
Yong-Sung Lee;
Panagiotakos, Georgia;
Tabar, Vivian;
Studer, Lorenz;
Sang-Hun Lee

Publication type:

Article

Enhancement of Polysialic Acid Expression Improves Function of Embryonic Stem-Derived Dopamine Neuron Grafts in Parkinsonian Mice.

Published in:

Stem Cells Translational Medicine, 2014, v. 3, n. 1, p. 108, doi. 10.5966/sctm.2013-0084

By:

BATTISTA, DANIELA;
GANAT, YOSIF;
EL MAAROUF, ABDERRAHMAN;
STUDER, LORENZ;
URS RUTISHAUSER

Publication type:

Article

Lipid droplets are a metabolic vulnerability in melanoma.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38831-9

By:

Lumaquin-Yin, Dianne;
Montal, Emily;
Johns, Eleanor;
Baggiolini, Arianna;
Huang, Ting-Hsiang;
Ma, Yilun;
LaPlante, Charlotte;
Suresh, Shruthy;
Studer, Lorenz;
White, Richard M.

Publication type:

Article

Transient inhibition of p53 enhances prime editing and cytosine base-editing efficiencies in human pluripotent stem cells.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34045-7

By:

Li, Mu;
Zhong, Aaron;
Wu, Youjun;
Sidharta, Mega;
Beaury, Michael;
Zhao, Xiaolan;
Studer, Lorenz;
Zhou, Ting

Publication type:

Article

Genipin rescues developmental and degenerative defects in familial dysautonomia models and accelerates axon regeneration.

Published in:

Science Translational Medicine, 2024, v. 16, n. 774, p. 1, doi. 10.1126/scitranslmed.adq2418

By:

Saito-Diaz, Kenyi;
Dietrich, Paula;
Saini, Tripti;
Rashid, Md Mamunur;
Wu, Hsueh-Fu;
Ishan, Mohamed;
Sun, Xin;
Bedillion, Sydney;
Patel, Archie Jayesh;
Prudden, Anthony Robert;
Wzientek, Camryn Gale;
Knight, Trinity Nora;
Chen, Ya-Wen;
Boons, Geert-Jan;
Chen, Shuibing;
Studer, Lorenz;
Tiemeyer, Michael;
Xu, Bingqian;
Dragatsis, Ioannis;
Liu, Hong-Xiang

Publication type:

Article

Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinsons disease.

Published in:

Brain: A Journal of Neurology, 2008, v. 131, n. 8, p. 2127, doi. 10.1093/brain/awn144

By:

Rosario Sanchez-Pernaute;
Hyojin Lee;
Michaela Patterson;
Casper Reske-Nielsen;
Takahito Yoshizaki;
Kai C. Sonntag;
Lorenz Studer;
Ole Isacson

Publication type:

Article

Retinoic Acid-Mediated Regulation of GLI3 Enables Efficient Motoneuron Derivation from Human ESCs in the Absence of Extrinsic SHH Activation.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 33, p. 11462, doi. 10.1523/JNEUROSCI.3046-14.2015

By:

Calder, Elizabeth L.;
Tchieu, Jason;
Steinbeck, Julius A.;
Edmund Tu;
Keros, Sotirios;
Shui-Wang Ying;
Jaiswal, Manoj K.;
Cornacchia, Daniela;
Goldstein, Peter A.;
Tabar, Viviane;
Studer, Lorenz

Publication type:

Article

Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 8, p. 2928, doi. 10.1172/JCI58767

By:

Ganat, Yosif M.;
Calder, Elizabeth L.;
Kriks, Sonja;
Nelander, Jenny;
Tu, Edmund Y.;
Jia, Fan;
Battista, Daniela;
Harrison, Neil;
Parmar, Malin;
Tomishima, Mark J.;
Rutishauser, Urs;
Studer, Lorenz

Publication type:

Article

Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 7, p. 1, doi. 10.1172/JCI58767

By:

Ganat, Yosif M.;
Calder, Elizabeth L.;
Kriks, Sonja;
Nelander, Jenny;
Tu, Edmund Y.;
Jia, Fan;
Battista, Daniela;
Harrison, Neil;
Parmar, Malin;
Tomishima, Mark J.;
Rutishauser, Urs;
Studer, Lorenz

Publication type:

Article

Too much Sonic, too few neurons.

Published in:

Nature Neuroscience, 2009, v. 12, n. 2, p. 107, doi. 10.1038/nn0209-107

By:

Fasano, Christopher A;
Studer, Lorenz

Publication type:

Article

A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07201-1

By:

Zhou, Ting;
Kim, Tae Wan;
Chong, Chi Nok;
Tan, Lei;
Amin, Sadaf;
Sadat Badieyan, Zohreh;
Mukherjee, Suranjit;
Ghazizadeh, Zaniar;
Zeng, Hui;
Guo, Min;
Crespo, Miguel;
Zhang, Tuo;
Kenyon, Reyn;
Robinson, Christopher L.;
Apostolou, Effie;
Wang, Hui;
Xiang, Jenny Zhaoying;
Evans, Todd;
Studer, Lorenz;
Chen, Shuibing

Publication type:

Article

IPSCs put to the test.

Published in:

2011

By:

Kim, Hyesoo;
Studer, Lorenz

Publication type:

Opinion

Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells.

Published in:

Nature Biotechnology, 2011, v. 29, n. 1, p. 73, doi. 10.1038/nbt.1717

By:

Papapetrou, Eirini P.;
Lee, Gabsang;
Malani, Nirav;
Setty, Manu;
Riviere, Isabelle;
Tirunagari, Laxmi M. S.;
Kadota, Kyuichi;
Roth, Shoshannah L.;
Giardina, Patricia;
Viale, Agnes;
Leslie, Christina;
Bushman, Frederic D.;
Studer, Lorenz;
Sadelain, Michel

Publication type:

Article

Expansion and maintenance of human embryonic stem cell–derived endothelial cells by TGFβ inhibition is Id1 dependent.

Published in:

Nature Biotechnology, 2010, v. 28, n. 2, p. 161, doi. 10.1038/nbt.1605

By:

James, Daylon;
Hyung-song Nam;
Seandel, Marco;
Nolan, Daniel;
Janovitz, Tyler;
Tomishima, Mark;
Studer, Lorenz;
Lee, Gabsang;
Lyden, David;
Benezra, Robert;
Zaninovic, Nikica;
Rosenwaks, Zev;
Rabbany, Sina Y.;
Rafii, Shahin

Publication type:

Article

Corrigendum: Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling.

Published in:

2009

By:

Chambers, Stuart M;
Fasano, Christopher A;
Papapetrou, Eirini P;
Tomishima, Mark;
Sadelain, Michel;
Studer, Lorenz

Publication type:

Correction Notice

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling.

Published in:

2009

By:

Chambers, Stuart M;
Fasano, Christopher A;
Papapetrou, Eirini P;
Tomishima, Mark;
Sadelain, Michel;
Studer, Lorenz

Publication type:

Letter

Corrigendum: Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells.

Published in:

2008

By:

Lee, Gabsang;
Kim, Hyesoo;
Elkabetz, Yechiel;
Al Shamy, George;
Panagiotakos, Georgia;
Barberi, Tiziano;
Tabar, Viviane;
Studer, Lorenz

Publication type:

Correction Notice

Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells.

Published in:

Nature Biotechnology, 2007, v. 25, n. 12, p. 1468, doi. 10.1038/nbt1365

By:

Gabsang Lee;
Hyesoo Kim;
Elkabetz, Yechiel;
Al Shamy, George;
Panagiotakos, Georgia;
Barberi, Tiziano;
Tabar, Viviane;
Studer, Lorenz

Publication type:

Article

Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain.

Published in:

Nature Biotechnology, 2005, v. 23, n. 5, p. 601, doi. 10.1038/nbt1088

By:

Tabar, Viviane;
Panagiotakos, Georgia;
Greenberg, Edward D;
Chan, Bill K;
Sadelain, Michel;
Gutin, Philip H;
Studer, Lorenz

Publication type:

Article

Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice.

Published in:

Nature Biotechnology, 2003, v. 21, n. 10, p. 1200, doi. 10.1038/nbt870

By:

Barberi, Tiziano;
Klivenyi, Peter;
Calingasan, Noel Y.;
Hyojin Lee, Noel Y.;
Kawamata, Hibiki;
Loonam, Kathleen;
Perrier, Anselme L.;
Bruses, Juan;
Rubio, Maria E.;
Topf, Norbert;
Tabar, Viviane;
Harrison, Neil L.;
Beal, M. Flint;
Moore, Malcolm A.S.;
Studer, Lorenz

Publication type:

Article

Stem cells with brainpower.

Published in:

Nature Biotechnology, 2001, v. 19, n. 12, p. 1117, doi. 10.1038/nbt1201-1117

By:

Studer, Lorenz

Publication type:

Article

Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells.

Published in:

Nature Biotechnology, 2000, v. 18, n. 6, p. 675, doi. 10.1038/76536

By:

Lee, Sang-Hun;
Lumelsky, Nadya;
Studer, Lorenz;
Auerbach, Jonathan M.;
McKay, Ron D.

Publication type:

Article

Evaluation of Developmental Toxicants and Signaling Pathways in a Functional Test Based on the Migration of Human Neural Crest Cells.

Published in:

Environmental Health Perspectives, 2012, v. 120, n. 8, p. 1116, doi. 10.1289/ehp.1104489

By:

Zimmer, Bastian;
Lee, Gabsang;
Balmer, Nina V.;
Meganathan, Kesavan;
Sachinidis, Agapios;
Studer, Lorenz;
Leist, Marcel

Publication type:

Article

Single-Molecule Analysis Reveals Changes in the DNA Replication Program for the POU5F1 Locus upon Human Embryonic Stem Cell Differentiation.

Published in:

Molecular & Cellular Biology, 2010, v. 30, n. 18, p. 12, doi. 10.1128/MCB.00380-10

By:

Schultz, Sherri S.;
Desbordes, Sabrina C.;
Zhuo Du;
Kosiyatrakul, Settapong;
Lipchina, Inna;
Studer, Lorenz;
Schildkraut, Carl L.

Publication type:

Article

Comparison of the Effects of the Neurotrophins on the Morphological Structure of Dopaminergic Neurons in Cultures of Rat Substantia Nigra.

Published in:

European Journal of Neuroscience, 1995, v. 7, n. 2, p. 223, doi. 10.1111/j.1460-9568.1995.tb01058.x

By:

Studer, Lorenz;
Spenger, Christian;
Seiler, Rolf W.;
Altar, C. Anthony;
Lindsay, Ronald M.;
Hyman, Carolyn

Publication type:

Article

The expanding role of miR-302-367 in pluripotency and reprogramming.

Published in:

Cell Cycle, 2012, v. 11, n. 8, p. 1517, doi. 10.4161/cc.19846

By:

Lipchina, Inna;
Studer, Lorenz;
Betel, Doron

Publication type:

Article

Dopaminergic neuronal differentiation from rat embryonic neural precursors by Nurr1 overexpression.

Published in:

Journal of Neurochemistry, 2003, v. 85, n. 6, p. 1443, doi. 10.1046/j.1471-4159.2003.01780.x

By:

Kim, Ju-Yeon;
Koh, Hyun Chul;
Lee, Ji-Yeon;
Chang, Mi-Yoon;
Kim, You-Chan;
Chung, Hee-Yong;
Son, Hyeon;
Lee, Yong-Sung;
Studer, Lorenz;
McKay, Ron;
Lee, Sang-Hun

Publication type:

Article

Recurrent chromosomal imbalances provide selective advantage to human embryonic stem cells under enhanced replicative stress conditions.

Published in:

Genes, Chromosomes & Cancer, 2021, v. 60, n. 4, p. 272, doi. 10.1002/gcc.22931

By:

Mus, Liselot M.;
Van Haver, Stéphane;
Popovic, Mina;
Trypsteen, Wim;
Lefever, Steve;
Zeltner, Nadja;
Ogando, Yudelca;
Jacobs, Eva Z.;
Denecker, Geertrui;
Sanders, Ellen;
Van Neste, Christophe;
Vanhauwaert, Suzanne;
Decaesteker, Bieke;
Deforce, Dieter;
Van Nieuwerburgh, Filip;
Mestdagh, Pieter;
Vandesompele, Jo;
Menten, Björn;
De Preter, Katleen;
Studer, Lorenz

Publication type:

Article

Robust and inducible genome editing via an all-in-one prime editor in human pluripotent stem cells.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-55104-1

By:

Wu, Youjun;
Zhong, Aaron;
Sidharta, Mega;
Kim, Tae Wan;
Ramirez, Bernny;
Persily, Benjamin;
Studer, Lorenz;
Zhou, Ting

Publication type:

Article

Suppression of ferroptosis by vitamin A or radical-trapping antioxidants is essential for neuronal development.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51996-1

By:

Tschuck, Juliane;
Padmanabhan Nair, Vidya;
Galhoz, Ana;
Zaratiegui, Carole;
Tai, Hin-Man;
Ciceri, Gabriele;
Rothenaigner, Ina;
Tchieu, Jason;
Stockwell, Brent R.;
Studer, Lorenz;
Cabianca, Daphne S.;
Menden, Michael P.;
Vincendeau, Michelle;
Hadian, Kamyar

Publication type:

Article

Transplanted dopamine neurons derived from primate ES cells preferentially innervate DARPP-32 striatal progenitors within the graft.

Published in:

European Journal of Neuroscience, 2006, v. 24, n. 7, p. 1885, doi. 10.1111/j.1460-9568.2006.05093.x

By:

Ferrari, Daniela;
Sanchez‐Pernaute, Rosario;
Lee, Hyojin;
Studer, Lorenz;
Isacson, Ole

Publication type:

Article

Optical bioluminescence imaging of human ES cell progeny in the rodent CNS.

Published in:

Journal of Neurochemistry, 2007, v. 102, n. 6, p. 2029, doi. 10.1111/j.1471-4159.2007.04681.x

By:

Bradbury, Michelle S.;
Panagiotakos, Georgia;
Chan, Bill K.;
Tomishima, Mark;
Zanzonico, Pat;
Vider, Jelena;
Ponomarev, Vladimir;
Studer, Lorenz;
Tabar, Viviane

Publication type:

Article

Induced pluripotent stem cell technology for the study of human disease.

Published in:

2010

By:

Lee, Gabsang;
Studer, Lorenz

Publication type:

Opinion

Transcriptional program of bone morphogenetic protein-2-induced epithelial and smooth muscle differentiation of pluripotent human embryonal carcinoma cells.

Published in:

Functional & Integrative Genomics, 2005, v. 5, n. 2, p. 59, doi. 10.1007/s10142-005-0132-7

By:

Chadalavada, Rajendrakumar S. V.;
Houldsworth, Jane;
Olshen, Adam B.;
Bosl, George J.;
Studer, Lorenz;
Chaganti, R. S. K.

Publication type:

Article

Deciphering human cell-autonomous anti-HSV-1 immunity in the central nervous system.

Published in:

Frontiers in Immunology, 2015, p. 1, doi. 10.3389/fimmu.2015.00208

By:

Lafaille, Fabien G.;
Ciancanelli, Michael J.;
Studer, Lorenz;
Smith, Gregory;
Notarangelo, Luigi;
Casanova, Jean-Laurent;
Zhang, Shen-Ying

Publication type:

Article

MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration.

Published in:

Nature Communications, 2014, v. 5, n. 4, p. 3633, doi. 10.1038/ncomms4633

By:

Cebrián, Carolina;
Zucca, Fabio A.;
Mauri, Pierluigi;
Steinbeck, Julius A.;
Studer, Lorenz;
Scherzer, Clemens R.;
Kanter, Ellen;
Budhu, Sadna;
Mandelbaum, Jonathan;
Vonsattel, Jean P.;
Zecca, Luigi;
Loike, John D.;
Sulzer, David

Publication type:

Article