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Testing Efficacy of Administration of the Antiaging Drug Rapamycin in a Nonhuman Primate, the Common Marmoset.
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- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2015, v. 70, n. 5, p. 577, doi. 10.1093/gerona/glu101
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- Publication type:
- Article
Rapamycin Extends Life Span in Apc<sup>Min/+</sup> Colon Cancer FAP Model.
- Published in:
- 2021
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- Publication type:
- journal article
Determinants of buildup of the toxic dopamine metabolite DOPAL in Parkinson's disease.
- Published in:
- Journal of Neurochemistry, 2013, v. 126, n. 5, p. 591, doi. 10.1111/jnc.12345
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- Publication type:
- Article
Evolutionary conservation of an atypical glucocorticoid-responsive element in the human tyrosine hydroxylase gene.
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- Journal of Neurochemistry, 2013, v. 126, n. 1, p. 19, doi. 10.1111/jnc.12294
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- Publication type:
- Article
Glutathione peroxidase 4 protects cortical neurons from oxidative injury and amyloid toxicity.
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- Journal of Neuroscience Research, 2006, v. 84, n. 1, p. 202, doi. 10.1002/jnr.20868
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- Publication type:
- Article
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
- Published in:
- Nature, 2009, v. 460, n. 7253, p. 392, doi. 10.1038/nature08221
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- Publication type:
- Article
Impaired aldehyde detoxification exacerbates motor deficits in an alpha‐synuclein mouse model of Parkinson's disease.
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- Brain & Behavior, 2023, v. 13, n. 9, p. 1, doi. 10.1002/brb3.3150
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- Publication type:
- Article
Evidence for retrograde degeneration of epinephrine neurons in Alzheimer's disease.
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- Annals of Neurology, 1988, v. 24, n. 4, p. 532, doi. 10.1002/ana.410240409
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- Publication type:
- Article
Transcriptional and Posttranscriptional Control of Tyrosine Hydroxylase Gene Expression During Persistent Stimulation of Pituitary Adenylate Cyclase-Activating Polypeptide Receptors on PC12 Cells: Regulation by Protein Kinase A-Dependent and Protein Kinase A-Independent Pathways
- Published in:
- Journal of Neurochemistry, 1998, v. 71, n. 2, p. 478, doi. 10.1046/j.1471-4159.1998.71020478.x
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- Publication type:
- Article
Prostaglandin H Synthetase-Mediated Metabolism of Dopamine: Implication for Parkinson's Disease.
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- Journal of Neurochemistry, 1995, v. 64, n. 4, p. 1645, doi. 10.1046/j.1471-4159.1995.64041645.x
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- Publication type:
- Article
Vasoactive Intestinal Polypeptide-Related Peptides Modulate Tyrosine Hydroxylase Gene Expression in PC12 Cells Through Multiple Adenylate Cyclase-Coupled Receptors.
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- Journal of Neurochemistry, 1993, v. 60, n. 3, p. 1018, doi. 10.1111/j.1471-4159.1993.tb03250.x
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- Publication type:
- Article
High-Affinity Uptake of Neurotransmitters in Rat Neostriatum: Effects of Aging.
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- Journal of Neurochemistry, 1984, v. 43, n. 6, p. 1766, doi. 10.1111/j.1471-4159.1984.tb06108.x
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- Publication type:
- Article
Development of primary osteoarthritis during aging in genetically diverse UM-HET3 mice.
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- Arthritis Research & Therapy, 2024, v. 26, n. 1, p. 1, doi. 10.1186/s13075-024-03349-y
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- Publication type:
- Article
Divergent tissue and sex effects of rapamycin on the proteasome-chaperone network of old mice.
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- Frontiers in Molecular Neuroscience, 2014, v. 7, p. 1, doi. 10.3389/fnmol.2014.00083
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- Publication type:
- Article
DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinson's disease.
- Published in:
- NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-023-00485-1
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- Publication type:
- Article
Evaluation of Resveratrol, Green Tea Extract, Curcumin, Oxaloacetic Acid, and Medium-Chain Triglyceride Oil on Life Span of Genetically Heterogeneous Mice.
- Published in:
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2013, v. 68, n. 1, p. 6, doi. 10.1093/gerona/gls070
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- Publication type:
- Article
Probing the Relationship Between Insulin Sensitivity and Longevity Using Genetically Modified Mice.
- Published in:
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2012, v. 67, n. 12, p. 1332, doi. 10.1093/gerona/gls199
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- Publication type:
- Article
Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice.
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- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2011, v. 66A, n. 2, p. 191, doi. 10.1093/gerona/glq178
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- Publication type:
- Article
The Role of mTOR Signaling in Controlling Mammalian Life Span: What a Fungicide Teaches Us About Longevity.
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- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2010, v. 65A, n. 6, p. 580, doi. 10.1093/gerona/glp212
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- Publication type:
- Article
Plasma Glucose and the Action of Calorie Restriction on Aging.
- Published in:
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2007, v. 62, n. 10, p. 1059, doi. 10.1093/gerona/62.10.1059
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- Publication type:
- Article
Housing Density Does Not Influence the Longevity Effect of Calorie Restriction.
- Published in:
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2005, v. 60, n. 12, p. 1510, doi. 10.1093/gerona/60.12.1510
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- Publication type:
- Article
Cognitive Dysfunction Precedes the Onset of Motor Symptoms in the MitoPark Mouse Model of Parkinson’s Disease.
- Published in:
- PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0071341
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- Publication type:
- Article
Neurodegeneration and Motor Dysfunction in Mice Lacking Cytosolic and Mitochondrial Aldehyde Dehydrogenases: Implications for Parkinson's Disease.
- Published in:
- PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031522
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- Publication type:
- Article
Inducing Autophagy by Rapamycin Before, but Not After, the Formation of Plaques and Tangles Ameliorates Cognitive Deficits.
- Published in:
- PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0025416
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- Publication type:
- Article
Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease.
- Published in:
- PLoS ONE, 2010, v. 5, n. 4, p. 1, doi. 10.1371/journal.pone.0009979
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- Publication type:
- Article
Rapamycin Reverses Elevated mTORC1 Signaling in Lamin A/C-Deficient Mice, Rescues Cardiac and Skeletal Muscle Function, and Extends Survival.
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- Science Translational Medicine, 2012, v. 4, n. 144, p. 1, doi. 10.1126/scitranslmed.3003802
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- Publication type:
- Article
WIN55,212-2, a cannabinoid receptor agonist, protects against nigrostriatal cell loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson’s disease.
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- European Journal of Neuroscience, 2009, v. 29, n. 11, p. 2177, doi. 10.1111/j.1460-9568.2009.06764.x
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- Publication type:
- Article
Changes in the gut microbiome and fermentation products concurrent with enhanced longevity in acarbose-treated mice.
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- BMC Microbiology, 2019, v. 19, n. 1, p. N.PAG, doi. 10.1186/s12866-019-1494-7
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- Publication type:
- Article
Dexamethasone Causes Hypertension in Rats Even Under Chemical Blockade of Peripheral Sympathetic Nerves.
- Published in:
- Frontiers in Neuroscience, 2019, v. 13, p. 1, doi. 10.3389/fnins.2019.01305
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- Publication type:
- Article
Regionally Selective Manifestations of Neostriatal Aging.
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- Annals of the New York Academy of Sciences, 1987, v. 515, n. 1, p. 161, doi. 10.1111/j.1749-6632.1988.tb32980.x
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- Publication type:
- Article
The Gehan test identifies life-extending compounds overlooked by the log-rank test in the NIA Interventions Testing Program: Metformin, Enalapril, caffeic acid phenethyl ester, green tea extract, and 17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride
- Published in:
- GeroScience, 2024, v. 46, n. 5, p. 4533, doi. 10.1007/s11357-024-01161-9
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- Publication type:
- Article
Castration reduces mortality and increases resilience in male mice: what is next?
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- GeroScience, 2024, v. 46, n. 2, p. 2787, doi. 10.1007/s11357-023-00973-5
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- Publication type:
- Article
Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used.
- Published in:
- GeroScience, 2024, v. 46, n. 1, p. 795, doi. 10.1007/s11357-023-01011-0
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- Publication type:
- Article
Long-term effects of canagliflozin treatment on the skeleton of aged UM-HET3 mice.
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- GeroScience, 2023, v. 45, n. 3, p. 1933, doi. 10.1007/s11357-023-00803-8
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- Publication type:
- Article
Canagliflozin retards age-related lesions in heart, kidney, liver, and adrenal gland in genetically heterogenous male mice.
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- GeroScience, 2023, v. 45, n. 1, p. 385, doi. 10.1007/s11357-022-00641-0
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- Publication type:
- Article
San Antonio Nathan Shock Center: your one-stop shop for aging research.
- Published in:
- GeroScience, 2021, v. 43, n. 5, p. 2105, doi. 10.1007/s11357-021-00417-y
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- Publication type:
- Article
Correction to: Hydrogen sulfide ameliorates aging-associated changes in the kidney.
- Published in:
- 2021
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- Publication type:
- Correction Notice
Hydrogen sulfide ameliorates aging-associated changes in the kidney.
- Published in:
- GeroScience, 2018, v. 40, n. 2, p. 163, doi. 10.1007/s11357-018-0018-y
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- Publication type:
- Article
Prepubertal castration eliminates sex differences in lifespan and growth trajectories in genetically heterogeneous mice.
- Published in:
- Aging Cell, 2023, v. 22, n. 8, p. 1, doi. 10.1111/acel.13891
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- Publication type:
- Article
Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice.
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- Aging Cell, 2022, v. 21, n. 12, p. 1, doi. 10.1111/acel.13724
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- Publication type:
- Article
17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex.
- Published in:
- Aging Cell, 2021, v. 20, n. 5, p. 1, doi. 10.1111/acel.13328
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- Publication type:
- Article
Rapamycin‐mediated mouse lifespan extension: Late‐life dosage regimes with sex‐specific effects.
- Published in:
- Aging Cell, 2020, v. 19, n. 11, p. 1, doi. 10.1111/acel.13269
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- Publication type:
- Article
Mobilization‐based transplantation of young‐donor hematopoietic stem cells extends lifespan in mice.
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- Aging Cell, 2020, v. 19, n. 3, p. 1, doi. 10.1111/acel.13110
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- Publication type:
- Article
Glycine supplementation extends lifespan of male and female mice.
- Published in:
- Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12953
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- Publication type:
- Article
Cardiolipin remodeling by ALCAT1 links mitochondrial dysfunction to Parkinson's diseases.
- Published in:
- Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12941
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- Publication type:
- Article
Genetically heterogeneous mice exhibit a female survival advantage that is age‐ and site‐specific: Results from a large multi‐site study.
- Published in:
- Aging Cell, 2019, v. 18, n. 3, p. 1, doi. 10.1111/acel.12905
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- Publication type:
- Article
Acarbose improves health and lifespan in aging HET3 mice.
- Published in:
- Aging Cell, 2019, v. 18, n. 2, p. N.PAG, doi. 10.1111/acel.12898
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- Publication type:
- Article
Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer.
- Published in:
- Aging Cell, 2016, v. 15, n. 5, p. 872, doi. 10.1111/acel.12496
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- Publication type:
- Article
Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males.
- Published in:
- Aging Cell, 2014, v. 13, n. 2, p. 273, doi. 10.1111/acel.12170
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- Publication type:
- Article
Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction.
- Published in:
- Aging Cell, 2014, v. 13, n. 3, p. 468, doi. 10.1111/acel.12194
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- Publication type:
- Article