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Safety and nonclinical and clinical pharmacokinetics of PC945, a novel inhaled triazole antifungal agent.
Published in:
Pharmacology Research & Perspectives, 2021, v. 9, n. 1, p. 1, doi. 10.1002/prp2.690
By:
- Cass, Lindsey;
- Murray, Alison;
- Davis, Amanda;
- Woodward, Kathy;
- Albayaty, Muna;
- Ito, Kazuhiro;
- Strong, Pete;
- Ayrton, John;
- Brindley, Charlie;
- Prosser, Jayne;
- Murray, John;
- French, Eddie;
- Haywood, Phillip;
- Wallis, Christopher;
- Rapeport, Garth
Publication type:
Article
Antifungal synergy of a topical triazole, PC945, with a systemic triazole against respiratory Aspergillus fumigatus infection.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-45890-w
By:
- Colley, Thomas;
- Sehra, Gurpreet;
- Daly, Leah;
- Kimura, Genki;
- Nakaoki, Takahiro;
- Nishimoto, Yuki;
- Kizawa, Yasuo;
- Strong, Pete;
- Rapeport, Garth;
- Ito, Kazuhiro
Publication type:
Article
Late therapeutic intervention with a respiratory syncytial virus L-protein polymerase inhibitor, PC786, on respiratory syncytial virus infection in human airway epithelium.
Published in:
2018
By:
- Brookes, Daniel W.;
- Coates, Matthew;
- Allen, Heather;
- Daly, Leah;
- Constant, Samuel;
- Huang, Song;
- Hows, Mark;
- Davis, Amanda;
- Cass, Lindsey;
- Ayrton, John;
- Knowles, Ian;
- Strong, Pete;
- Rapeport, Garth;
- Ito, Kazuhiro
Publication type:
journal article
PC945, a Novel Inhaled Antifungal Agent, for the Treatment of Respiratory Fungal Infections.
Published in:
Journal of Fungi, 2020, v. 6, n. 4, p. 1, doi. 10.3390/jof6040373
By:
- Murray, Alison;
- Cass, Lindsey;
- Kazuhiro Ito;
- Pagani, Nicole;
- Armstrong-James, Darius;
- Dalal, Paras;
- Reed, Anna;
- Strong, Pete
Publication type:
Article
Effects of intranasally dosed posaconazole on fungal load and biomarkers in Aspergillus fumigatus infected immunocompromised mice.
Published in:
Mycoses, 2017, v. 60, n. 11, p. 728, doi. 10.1111/myc.12653
By:
- Kimura, Genki;
- Nakaoki, Takahiro;
- Nishimoto, Yuki;
- Suzuki, Yuto;
- Rapeport, Garth;
- Strong, Pete;
- Ito, Kazuhiro;
- Kizawa, Yasuo
Publication type:
Article
Safety and Antiviral Effects of Nebulized PC786 in a Respiratory Syncytial Virus Challenge Study.
Published in:
Journal of Infectious Diseases, 2022, v. 225, n. 12, p. 2087, doi. 10.1093/infdis/jiaa716
By:
- DeVincenzo, John;
- Cass, Lindsey;
- Murray, Alison;
- Woodward, Kathy;
- Meals, Elizabeth;
- Coates, Matthew;
- Daly, Leah;
- Wheeler, Vicky;
- Mori, Julie;
- Brindley, Charlie;
- Davis, Amanda;
- McCurdy, Meabh;
- Ito, Kazuhiro;
- Murray, Bryan;
- Strong, Pete;
- Rapeport, Garth
Publication type:
Article
Anti-fungal activity of a novel triazole, PC1244, against emerging azole-resistant Aspergillus fumigatus and other species of Aspergillus.
Published in:
2019
By:
- Colley, Thomas;
- Sharma, Cheshta;
- Alanio, Alexandre;
- Kimura, Genki;
- Daly, Leah;
- Nakaoki, Takahiro;
- Nishimoto, Yuki;
- Bretagne, Stéphane;
- Kizawa, Yasuo;
- Strong, Pete;
- Rapeport, Garth;
- Ito, Kazuhiro;
- Meis, Jacques F;
- Chowdhary, Anuradha
Publication type:
journal article
In vitro antifungal activity of a novel topical triazole PC945 against emerging yeast Candida auris.
Published in:
2019
By:
- Rudramurthy, Shivaprakash M;
- Colley, Thomas;
- Abdolrasouli, Alireza;
- Ashman, Jed;
- Dhaliwal, Manpreet;
- Kaur, Harsimran;
- Armstrong-James, Darius;
- Strong, Pete;
- Rapeport, Garth;
- Schelenz, Silke;
- Ito, Kazuhiro;
- Chakrabarti, Arunaloke
Publication type:
journal article

Found: 8